CN103652556A - Radix astragali, couchgrass root and rhizoma dioscoreae chewable tablets and preparation method - Google Patents
Radix astragali, couchgrass root and rhizoma dioscoreae chewable tablets and preparation method Download PDFInfo
- Publication number
- CN103652556A CN103652556A CN201310665473.9A CN201310665473A CN103652556A CN 103652556 A CN103652556 A CN 103652556A CN 201310665473 A CN201310665473 A CN 201310665473A CN 103652556 A CN103652556 A CN 103652556A
- Authority
- CN
- China
- Prior art keywords
- chinese yam
- radix astragali
- chewable tablets
- lalang grass
- parts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000009636 Huang Qi Substances 0.000 title claims abstract description 36
- 239000007910 chewable tablet Substances 0.000 title claims abstract description 28
- 238000002360 preparation method Methods 0.000 title claims description 12
- 241000508725 Elymus repens Species 0.000 title abstract 4
- 239000001100 (2S)-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chroman-4-one Substances 0.000 claims abstract description 18
- 229920000168 Microcrystalline cellulose Polymers 0.000 claims abstract description 18
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 claims abstract description 18
- AIONOLUJZLIMTK-AWEZNQCLSA-N hesperetin Chemical compound C1=C(O)C(OC)=CC=C1[C@H]1OC2=CC(O)=CC(O)=C2C(=O)C1 AIONOLUJZLIMTK-AWEZNQCLSA-N 0.000 claims abstract description 18
- 229960001587 hesperetin Drugs 0.000 claims abstract description 18
- AIONOLUJZLIMTK-UHFFFAOYSA-N hesperetin Natural products C1=C(O)C(OC)=CC=C1C1OC2=CC(O)=CC(O)=C2C(=O)C1 AIONOLUJZLIMTK-UHFFFAOYSA-N 0.000 claims abstract description 18
- 235000010209 hesperetin Nutrition 0.000 claims abstract description 18
- FTODBIPDTXRIGS-UHFFFAOYSA-N homoeriodictyol Natural products C1=C(O)C(OC)=CC(C2OC3=CC(O)=CC(O)=C3C(=O)C2)=C1 FTODBIPDTXRIGS-UHFFFAOYSA-N 0.000 claims abstract description 18
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 claims abstract description 18
- 235000019813 microcrystalline cellulose Nutrition 0.000 claims abstract description 18
- 239000000811 xylitol Substances 0.000 claims abstract description 18
- 235000010447 xylitol Nutrition 0.000 claims abstract description 18
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 claims abstract description 18
- 229960002675 xylitol Drugs 0.000 claims abstract description 18
- 239000008108 microcrystalline cellulose Substances 0.000 claims abstract description 14
- 229940016286 microcrystalline cellulose Drugs 0.000 claims abstract description 14
- 229920002472 Starch Polymers 0.000 claims abstract description 13
- WHGYBXFWUBPSRW-FOUAGVGXSA-N beta-cyclodextrin Chemical compound OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)CO)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1CO WHGYBXFWUBPSRW-FOUAGVGXSA-N 0.000 claims abstract description 13
- 239000008107 starch Substances 0.000 claims abstract description 13
- 235000019698 starch Nutrition 0.000 claims abstract description 13
- 235000002722 Dioscorea batatas Nutrition 0.000 claims description 44
- 235000006536 Dioscorea esculenta Nutrition 0.000 claims description 44
- 240000001811 Dioscorea oppositifolia Species 0.000 claims description 44
- 235000003416 Dioscorea oppositifolia Nutrition 0.000 claims description 44
- 244000025254 Cannabis sativa Species 0.000 claims description 37
- 241001598107 Imperata Species 0.000 claims description 37
- 239000011812 mixed powder Substances 0.000 claims description 25
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 21
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 claims description 17
- 235000009508 confectionery Nutrition 0.000 claims description 17
- 239000000203 mixture Substances 0.000 claims description 17
- 239000002245 particle Substances 0.000 claims description 17
- 239000011122 softwood Substances 0.000 claims description 15
- 239000003826 tablet Substances 0.000 claims description 15
- WHGYBXFWUBPSRW-UHFFFAOYSA-N Cycloheptaamylose Natural products O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO WHGYBXFWUBPSRW-UHFFFAOYSA-N 0.000 claims description 12
- 102000004407 Lactalbumin Human genes 0.000 claims description 12
- 108090000942 Lactalbumin Proteins 0.000 claims description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 12
- 239000000843 powder Substances 0.000 claims description 10
- 230000001954 sterilising effect Effects 0.000 claims description 10
- 238000004659 sterilization and disinfection Methods 0.000 claims description 10
- 239000000084 colloidal system Substances 0.000 claims description 7
- 239000000706 filtrate Substances 0.000 claims description 7
- 238000000227 grinding Methods 0.000 claims description 7
- 239000000126 substance Substances 0.000 claims description 7
- 241000545442 Radix Species 0.000 claims description 5
- 235000004879 dioscorea Nutrition 0.000 claims description 5
- 238000001035 drying Methods 0.000 claims description 5
- IDGUHHHQCWSQLU-UHFFFAOYSA-N ethanol;hydrate Chemical compound O.CCO IDGUHHHQCWSQLU-UHFFFAOYSA-N 0.000 claims description 5
- 238000001914 filtration Methods 0.000 claims description 5
- 238000005469 granulation Methods 0.000 claims description 5
- 230000003179 granulation Effects 0.000 claims description 5
- 239000000314 lubricant Substances 0.000 claims description 5
- 239000000463 material Substances 0.000 claims description 5
- 238000002156 mixing Methods 0.000 claims description 5
- 238000012856 packing Methods 0.000 claims description 5
- 238000010298 pulverizing process Methods 0.000 claims description 5
- 239000000080 wetting agent Substances 0.000 claims description 5
- 210000004072 lung Anatomy 0.000 abstract description 12
- 208000006673 asthma Diseases 0.000 abstract description 3
- 230000002708 enhancing effect Effects 0.000 abstract description 3
- 230000036039 immunity Effects 0.000 abstract description 3
- 230000007812 deficiency Effects 0.000 abstract description 2
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 abstract 2
- 229920000858 Cyclodextrin Polymers 0.000 abstract 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 abstract 1
- 229930195725 Mannitol Natural products 0.000 abstract 1
- 108010046377 Whey Proteins Proteins 0.000 abstract 1
- 102000007544 Whey Proteins Human genes 0.000 abstract 1
- 239000001202 beta-cyclodextrine Substances 0.000 abstract 1
- 235000011175 beta-cyclodextrine Nutrition 0.000 abstract 1
- 229920003063 hydroxymethyl cellulose Polymers 0.000 abstract 1
- 229940031574 hydroxymethyl cellulose Drugs 0.000 abstract 1
- 235000019359 magnesium stearate Nutrition 0.000 abstract 1
- 239000000594 mannitol Substances 0.000 abstract 1
- 235000010355 mannitol Nutrition 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 235000021119 whey protein Nutrition 0.000 abstract 1
- 201000010099 disease Diseases 0.000 description 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 6
- 210000003734 kidney Anatomy 0.000 description 5
- 206010011224 Cough Diseases 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 230000029058 respiratory gaseous exchange Effects 0.000 description 2
- 206010006458 Bronchitis chronic Diseases 0.000 description 1
- 208000000059 Dyspnea Diseases 0.000 description 1
- 206010013975 Dyspnoeas Diseases 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 206010006451 bronchitis Diseases 0.000 description 1
- 208000007451 chronic bronchitis Diseases 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 235000013402 health food Nutrition 0.000 description 1
- 230000004630 mental health Effects 0.000 description 1
- KRTSDMXIXPKRQR-AATRIKPKSA-N monocrotophos Chemical compound CNC(=O)\C=C(/C)OP(=O)(OC)OC KRTSDMXIXPKRQR-AATRIKPKSA-N 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/30—Foods or foodstuffs containing additives; Preparation or treatment thereof containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/20—Agglomerating; Granulating; Tabletting
- A23P10/28—Tabletting; Making food bars by compression of a dry powdered mixture
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The invention discloses radix astragali, couchgrass root and rhizoma dioscoreae chewable tablets which comprise the following components in parts by weight: 3-9 parts of radix astragali, 3-9 parts of couchgrass root, 0.05-0.25 part of liquoric root, 3-7 parts of rhizoma dioscoreae, 1-3 parts of microcrystalline cellulose, 0.02-0.06 part of whey protein, 0.02-0.04 part of beta-cyclodextrine, 8-12 parts of starch, 0.001-0.003 part of hesperetin, 0.01-0.03 part of xylitol, 0.01-0.03 part of mannitol, 0.01-0.03 part of hydroxymethyl cellulose and 0.01-0.03 part of magnesium stearate. The radix astragali, couchgrass root and rhizoma dioscoreae chewable tablets disclosed by the invention have the functions of tonifying the lung, clearing heat and moistening dryness and enhancing immunity, and are suitable for asthma and worse asthma in winter caused by deficiency of lung qi and yin and lung qi failing in purification.
Description
Technical field
The invention belongs to nutritional health food field, be specially a kind of Radix Astragali lalang grass rhizome Chinese yam chewable tablets and preparation method.
Background technology
Motherland's medical science is thought, the lung being the dominator of QI, the kidney being the root of QI; The lung governing exhalation, kidney governing inspiration.With the passing of time many lungs kidney is all sick to cough the disease of breathing heavily, and above has phlegm heat in lung, under have the deficiency of the kidney yin, control when kidney tonifying clearing lung-heat, strengthening vital QI to eliminate pathogenic factors.Chronic bronchitis, bronchial astehma belong to motherland's medical science cough, dyspnea, heavy breathing card category, are common clinical, frequently-occurring disease.Illness multiterminal, the interpretation of the cause, onset and process of an illness is complicated, prolonging mistake of a specified duration controls, often cause that lung is opened, palpitaition, oedema and occur many critical change diseases, because such disease causes very large impact to people's physical and mental health, though treat at present this type of disease, have multi-medicament, but for various reasons, still the medicine of weary special efficacy, therefore the treatment of this type of disease is always paid attention to by doctor, and dietotherapy is the best method of bringing for a long time auxiliaring effect.
Summary of the invention
For above-mentioned situation, technical problem solved by the invention is to provide Radix Astragali lalang grass rhizome Chinese yam chewable tablets and the preparation method of a kind of help lungs, clearing heat and moistening dryness, enhancing immunity, to solve the problem proposing in above-mentioned background technology.
For achieving the above object, the invention provides following technical scheme:
A Radix Astragali lalang grass rhizome Chinese yam chewable tablets, comprises following weight portion composition: Radix Astragali 3-9 part, lalang grass rhizome 3-9 part, Radix Glycyrrhizae 0.05-0.25 part, Chinese yam 3-7 part, microcrystalline cellulose 1-3 part, lactalbumin 0.02-0.06 part, cycloheptaamylose 0.02-0.04 part, starch 8-12 part, hesperetin 0.001-0.003 part, xylitol 0.01-0.03 part, sweet mellow wine 0.01-0.03 part, CMC 0.01-0.03 part, dolomol 0.01-0.03 part.
As preferably, described a kind of Radix Astragali lalang grass rhizome Chinese yam chewable tablets, comprises following weight portion composition: 6 parts of the Radixs Astragali, 6 parts of lalang grass rhizomes, 0.15 part, Radix Glycyrrhizae, 5 parts of Chinese yams, 2 parts of microcrystalline celluloses, 0.04 part of lactalbumin, 0.03 part of cycloheptaamylose, 10 parts of starch, 0.002 part of hesperetin, 0.02 part of xylitol, 0.02 part, sweet mellow wine, 0.02 part of CMC, 0.02 part of dolomol.
A preparation method for Radix Astragali lalang grass rhizome Chinese yam chewable tablets, comprises the following steps:
(1) get fresh Chinese yam and clean peeling, put into 0.2% citric acid solution and soak 10-30min, again clean, drain surface moisture, put into beater and pull an oar, then with colloid mill, first roughly grind 1-2 time, and then fine grinding 1-2 time, defibrination temperature is controlled between 40-50 ℃ of scope, and dry substance concentration is controlled to 9-11%, Chinese yam pulp particle degree is controlled between 600-800um, standby;
(2) get the Radix Astragali, lalang grass rhizome, Radix Glycyrrhizae and add 3-10 times of water gaging and decoct 1-5 time, each 1-3 hour, collecting decoction, filtration, filtrate is concentrated into the thick paste that within the scope of 50-90 ℃, relative density is 1.10-1.25, standby;
(3) get microcrystalline cellulose, cycloheptaamylose, hesperetin, xylitol, sweet mellow wine, CMC, dolomol and pulverize respectively, cross respectively 120 mesh sieves standby;
(4) thick paste in the Chinese yam in step (1), step (2) and starch are placed in to mixer mixing 10-30 minute, above-mentioned mixed powder being placed in to micronizer pulverizes again, be ground into the Ultramicro-powder of 3-6 μ m, to above-mentioned Ultramicro-powder, add beta-schardinger dextrin-, hesperetin, and fully mix, obtain mixed powder A;
(5) microcrystalline cellulose after above-mentioned pulverizing, xylitol, sweet mellow wine, CMC mixed and stirred with the mixed powder A in lactalbumin, step (4), obtaining mixed powder B;
(6) the mixed powder B in step (5) is slowly added to the ethanol water of wetting agent 95%, adjust humidity of materials, make softwood, the soft durometer standard of softwood can be agglomerating for pinching with hand, and light pressure fallen apart, and the softwood making carried out in comminutor to granulation, cross 20 mesh sieves, obtain wet grain;
(7) wet grain is placed in to temperature and is dried at the drying box of 50-65 ℃, be dried to its water content below 5%, then be placed in airtight container temperature is cooled to 18-23 ℃, obtain dried particles;
(8) in dried particles, add dolomol as lubricant, mix, be placed in tablet press machine compressing tablet;
(9) tablet of compacting adopts microwave sterilization, and the temperature of microwave is within the scope of 92-95 ℃, and sterilization time is 3-8 minute, finally adopts lucifuge packing, obtains Radix Astragali lalang grass rhizome Chinese yam chewable tablets.
In described step (1), get fresh Chinese yam and clean peeling, put into 0.2% citric acid solution and soak 10min, again clean, drain surface moisture, put into beater and pull an oar, then with colloid mill, first roughly grind 2 times, and then fine grinding 1 time, defibrination temperature is controlled between 45 ℃ of scopes, and dry substance concentration is controlled to 9%, and Chinese yam pulp particle degree is controlled at 700um.
In described step (2), get the Radix Astragali, lalang grass rhizome, Radix Glycyrrhizae and add 10 times of water gagings and decoct 2 times, each 1 hour, collecting decoction, filtered, and filtrate is concentrated into the thick paste that within the scope of 85 ℃, relative density is 1.25.
Every described of chewable tablets is 0.6g-3.5g.
In sum, beneficial effect of the present invention:
The present invention has help lungs, clearing heat and moistening dryness, enhancing immunity.Be applicable to due to lung qi Yin bivacuity, lung qi obstruction asthma more than, winter more so.
The specific embodiment
Below in conjunction with the embodiment of the present invention, the technical scheme in the embodiment of the present invention is clearly and completely described, obviously, described embodiment is only the present invention's part embodiment, rather than whole embodiment.Embodiment based in the present invention, those of ordinary skills, not making the every other embodiment obtaining under creative work prerequisite, belong to the scope of protection of the invention.
Embodiment 1
A Radix Astragali lalang grass rhizome Chinese yam chewable tablets, comprises following weight portion composition: 3 parts of the Radixs Astragali, 3 parts of lalang grass rhizomes, 0.05 part, Radix Glycyrrhizae, 3 parts of Chinese yams, 1 part of microcrystalline cellulose, 0.02 part of lactalbumin, 0.02 part of cycloheptaamylose, 8 parts of starch, 0.001 part of hesperetin, 0.01 part of xylitol, 0.01 part, sweet mellow wine, 0.01 part of CMC, 0.01 part of dolomol.
A preparation method for Radix Astragali lalang grass rhizome Chinese yam chewable tablets, comprises the following steps:
(1) get fresh Chinese yam and clean peeling, put into 0.2% citric acid solution and soak 10-30min, again clean, drain surface moisture, put into beater and pull an oar, then with colloid mill, first roughly grind 1-2 time, and then fine grinding 1-2 time, defibrination temperature is controlled between 40-50 ℃ of scope, and dry substance concentration is controlled to 9-11%, Chinese yam pulp particle degree is controlled between 600-800um, standby;
(2) get the Radix Astragali, lalang grass rhizome, Radix Glycyrrhizae and add 3-10 times of water gaging and decoct 1-5 time, each 1-3 hour, collecting decoction, filtration, filtrate is concentrated into the thick paste that within the scope of 50-90 ℃, relative density is 1.10-1.25, standby;
(3) get microcrystalline cellulose, cycloheptaamylose, hesperetin, xylitol, sweet mellow wine, CMC, dolomol and pulverize respectively, cross respectively 120 mesh sieves standby;
(4) thick paste in the Chinese yam in step (1), step (2) and starch are placed in to mixer mixing 10-30 minute, above-mentioned mixed powder being placed in to micronizer pulverizes again, be ground into the Ultramicro-powder of 3-6 μ m, to above-mentioned Ultramicro-powder, add beta-schardinger dextrin-, hesperetin, and fully mix, obtain mixed powder A;
(5) microcrystalline cellulose after above-mentioned pulverizing, xylitol, sweet mellow wine, CMC mixed and stirred with the mixed powder A in lactalbumin, step (4), obtaining mixed powder B;
(6) the mixed powder B in step (5) is slowly added to the ethanol water of wetting agent 95%, adjust humidity of materials, make softwood, the soft durometer standard of softwood can be agglomerating for pinching with hand, and light pressure fallen apart, and the softwood making carried out in comminutor to granulation, cross 20 mesh sieves, obtain wet grain;
(7) wet grain is placed in to temperature and is dried at the drying box of 50-65 ℃, be dried to its water content below 5%, then be placed in airtight container temperature is cooled to 18-23 ℃, obtain dried particles;
(8) in dried particles, add dolomol as lubricant, mix, be placed in tablet press machine compressing tablet;
(9) tablet of compacting adopts microwave sterilization, and the temperature of microwave is within the scope of 92-95 ℃, and sterilization time is 3-8 minute, finally adopts lucifuge packing, obtains Radix Astragali lalang grass rhizome Chinese yam chewable tablets.
Embodiment 2
A Radix Astragali lalang grass rhizome Chinese yam chewable tablets, comprises following weight portion composition: 6 parts of the Radixs Astragali, 6 parts of lalang grass rhizomes, 0.15 part, Radix Glycyrrhizae, 5 parts of Chinese yams, 2 parts of microcrystalline celluloses, 0.04 part of lactalbumin, 0.03 part of cycloheptaamylose, 10 parts of starch, 0.002 part of hesperetin, 0.02 part of xylitol, 0.02 part, sweet mellow wine, 0.02 part of CMC, 0.02 part of dolomol.
A preparation method for Radix Astragali lalang grass rhizome Chinese yam chewable tablets, comprises the following steps:
(1) get fresh Chinese yam and clean peeling, put into 0.2% citric acid solution and soak 10-30min, again clean, drain surface moisture, put into beater and pull an oar, then with colloid mill, first roughly grind 1-2 time, and then fine grinding 1-2 time, defibrination temperature is controlled between 40-50 ℃ of scope, and dry substance concentration is controlled to 9-11%, Chinese yam pulp particle degree is controlled between 600-800um, standby;
(2) get the Radix Astragali, lalang grass rhizome, Radix Glycyrrhizae and add 3-10 times of water gaging and decoct 1-5 time, each 1-3 hour, collecting decoction, filtration, filtrate is concentrated into the thick paste that within the scope of 50-90 ℃, relative density is 1.10-1.25, standby;
(3) get microcrystalline cellulose, cycloheptaamylose, hesperetin, xylitol, sweet mellow wine, CMC, dolomol and pulverize respectively, cross respectively 120 mesh sieves standby;
(4) thick paste in the Chinese yam in step (1), step (2) and starch are placed in to mixer mixing 10-30 minute, above-mentioned mixed powder being placed in to micronizer pulverizes again, be ground into the Ultramicro-powder of 3-6 μ m, to above-mentioned Ultramicro-powder, add beta-schardinger dextrin-, hesperetin, and fully mix, obtain mixed powder A;
(5) microcrystalline cellulose after above-mentioned pulverizing, xylitol, sweet mellow wine, CMC mixed and stirred with the mixed powder A in lactalbumin, step (4), obtaining mixed powder B;
(6) the mixed powder B in step (5) is slowly added to the ethanol water of wetting agent 95%, adjust humidity of materials, make softwood, the soft durometer standard of softwood can be agglomerating for pinching with hand, and light pressure fallen apart, and the softwood making carried out in comminutor to granulation, cross 20 mesh sieves, obtain wet grain;
(7) wet grain is placed in to temperature and is dried at the drying box of 50-65 ℃, be dried to its water content below 5%, then be placed in airtight container temperature is cooled to 18-23 ℃, obtain dried particles;
(8) in dried particles, add dolomol as lubricant, mix, be placed in tablet press machine compressing tablet;
(9) tablet of compacting adopts microwave sterilization, and the temperature of microwave is within the scope of 92-95 ℃, and sterilization time is 3-8 minute, finally adopts lucifuge packing, obtains Radix Astragali lalang grass rhizome Chinese yam chewable tablets.
Embodiment 3
A Radix Astragali lalang grass rhizome Chinese yam chewable tablets, comprises following weight portion composition: 9 parts of the Radixs Astragali, 9 parts of lalang grass rhizomes, 0.25 part, Radix Glycyrrhizae, 7 parts of Chinese yams, 3 parts of microcrystalline celluloses, 0.06 part of lactalbumin, 0.04 part of cycloheptaamylose, 12 parts of starch, 0.003 part of hesperetin, 0.03 part of xylitol, 0.03 part, sweet mellow wine, 0.03 part of CMC, 0.03 part of dolomol.
A preparation method for Radix Astragali lalang grass rhizome Chinese yam chewable tablets, comprises the following steps:
(1) get fresh Chinese yam and clean peeling, put into 0.2% citric acid solution and soak 10-30min, again clean, drain surface moisture, put into beater and pull an oar, then with colloid mill, first roughly grind 1-2 time, and then fine grinding 1-2 time, defibrination temperature is controlled between 40-50 ℃ of scope, and dry substance concentration is controlled to 9-11%, Chinese yam pulp particle degree is controlled between 600-800um, standby;
(2) get the Radix Astragali, lalang grass rhizome, Radix Glycyrrhizae and add 3-10 times of water gaging and decoct 1-5 time, each 1-3 hour, collecting decoction, filtration, filtrate is concentrated into the thick paste that within the scope of 50-90 ℃, relative density is 1.10-1.25, standby;
(3) get microcrystalline cellulose, cycloheptaamylose, hesperetin, xylitol, sweet mellow wine, CMC, dolomol and pulverize respectively, cross respectively 120 mesh sieves standby;
(4) thick paste in the Chinese yam in step (1), step (2) and starch are placed in to mixer mixing 10-30 minute, above-mentioned mixed powder being placed in to micronizer pulverizes again, be ground into the Ultramicro-powder of 3-6 μ m, to above-mentioned Ultramicro-powder, add beta-schardinger dextrin-, hesperetin, and fully mix, obtain mixed powder A;
(5) microcrystalline cellulose after above-mentioned pulverizing, xylitol, sweet mellow wine, CMC mixed and stirred with the mixed powder A in lactalbumin, step (4), obtaining mixed powder B;
(6) the mixed powder B in step (5) is slowly added to the ethanol water of wetting agent 95%, adjust humidity of materials, make softwood, the soft durometer standard of softwood can be agglomerating for pinching with hand, and light pressure fallen apart, and the softwood making carried out in comminutor to granulation, cross 20 mesh sieves, obtain wet grain;
(7) wet grain is placed in to temperature and is dried at the drying box of 50-65 ℃, be dried to its water content below 5%, then be placed in airtight container temperature is cooled to 18-23 ℃, obtain dried particles;
(8) in dried particles, add dolomol as lubricant, mix, be placed in tablet press machine compressing tablet;
(9) tablet of compacting adopts microwave sterilization, and the temperature of microwave is within the scope of 92-95 ℃, and sterilization time is 3-8 minute, finally adopts lucifuge packing, obtains Radix Astragali lalang grass rhizome Chinese yam chewable tablets.
To those skilled in the art, obviously the invention is not restricted to the details of above-mentioned one exemplary embodiment, and in the situation that not deviating from spirit of the present invention or essential characteristic, can realize the present invention with other concrete form.Therefore, no matter from which point, all should regard embodiment as exemplary, and be nonrestrictive, scope of the present invention is limited by claims rather than above-mentioned explanation, is therefore intended to include in the present invention dropping on the implication that is equal to important document of claim and all changes in scope.
In addition, be to be understood that, although this description is described according to embodiment, but not each embodiment only comprises an independently technical scheme, this narrating mode of description is only for clarity sake, those skilled in the art should make description as a whole, and the technical scheme in each embodiment also can, through appropriately combined, form other embodiments that it will be appreciated by those skilled in the art that.
Claims (6)
1. a Radix Astragali lalang grass rhizome Chinese yam chewable tablets, is characterized in that: comprise following weight portion composition: Radix Astragali 3-9 part, lalang grass rhizome 3-9 part, Radix Glycyrrhizae 0.05-0.25 part, Chinese yam 3-7 part, microcrystalline cellulose 1-3 part, lactalbumin 0.02-0.06 part, cycloheptaamylose 0.02-0.04 part, starch 8-12 part, hesperetin 0.001-0.003 part, xylitol 0.01-0.03 part, sweet mellow wine 0.01-0.03 part, CMC 0.01-0.03 part, dolomol 0.01-0.03 part.
2. a kind of Radix Astragali lalang grass rhizome Chinese yam chewable tablets according to claim 1, is characterized in that: comprise following weight portion composition: 6 parts of the Radixs Astragali, 6 parts of lalang grass rhizomes, 0.15 part, Radix Glycyrrhizae, 5 parts of Chinese yams, 2 parts of microcrystalline celluloses, 0.04 part of lactalbumin, 0.03 part of cycloheptaamylose, 10 parts of starch, 0.002 part of hesperetin, 0.02 part of xylitol, 0.02 part, sweet mellow wine, 0.02 part of CMC, 0.02 part of dolomol.
3. a preparation method for Radix Astragali lalang grass rhizome Chinese yam chewable tablets, is characterized in that: comprise the following steps:
(1) get fresh Chinese yam and clean peeling, put into 0.2% citric acid solution and soak 10-30min, again clean, drain surface moisture, put into beater and pull an oar, then with colloid mill, first roughly grind 1-2 time, and then fine grinding 1-2 time, defibrination temperature is controlled between 40-50 ℃ of scope, and dry substance concentration is controlled to 9-11%, Chinese yam pulp particle degree is controlled between 600-800um, standby;
(2) get the Radix Astragali, lalang grass rhizome, Radix Glycyrrhizae and add 3-10 times of water gaging and decoct 1-5 time, each 1-3 hour, collecting decoction, filtration, filtrate is concentrated into the thick paste that within the scope of 50-90 ℃, relative density is 1.10-1.25, standby;
(3) get microcrystalline cellulose, cycloheptaamylose, hesperetin, xylitol, sweet mellow wine, CMC, dolomol and pulverize respectively, cross respectively 120 mesh sieves standby;
(4) thick paste in the Chinese yam in step (1), step (2) and starch are placed in to mixer mixing 10-30 minute, above-mentioned mixed powder being placed in to micronizer pulverizes again, be ground into the Ultramicro-powder of 3-6 μ m, to above-mentioned Ultramicro-powder, add beta-schardinger dextrin-, hesperetin, and fully mix, obtain mixed powder A;
(5) microcrystalline cellulose after above-mentioned pulverizing, xylitol, sweet mellow wine, CMC mixed and stirred with the mixed powder A in lactalbumin, step (4), obtaining mixed powder B;
(6) the mixed powder B in step (5) is slowly added to the ethanol water of wetting agent 95%, adjust humidity of materials, make softwood, the soft durometer standard of softwood can be agglomerating for pinching with hand, and light pressure fallen apart, and the softwood making carried out in comminutor to granulation, cross 20 mesh sieves, obtain wet grain;
(7) wet grain is placed in to temperature and is dried at the drying box of 50-65 ℃, be dried to its water content below 5%, then be placed in airtight container temperature is cooled to 18-23 ℃, obtain dried particles;
(8) in dried particles, add dolomol as lubricant, mix, be placed in tablet press machine compressing tablet;
(9) tablet of compacting adopts microwave sterilization, and the temperature of microwave is within the scope of 92-95 ℃, and sterilization time is 3-8 minute, finally adopts lucifuge packing, obtains Radix Astragali lalang grass rhizome Chinese yam chewable tablets.
4. the preparation method of a kind of Radix Astragali lalang grass rhizome Chinese yam chewable tablets according to claim 3, it is characterized in that: in described step (1), get fresh Chinese yam and clean peeling, put into 0.2% citric acid solution and soak 10min, again clean, drain surface moisture, putting into beater pulls an oar, then with colloid mill, first roughly grind 2 times, and then fine grinding 1 time, defibrination temperature is controlled between 45 ℃ of scopes, dry substance concentration is controlled to 9%, and Chinese yam pulp particle degree is controlled at 700um.
5. the preparation method of a kind of Radix Astragali lalang grass rhizome Chinese yam chewable tablets according to claim 3, it is characterized in that: in described step (2), get the Radix Astragali, lalang grass rhizome, Radix Glycyrrhizae and add 10 times of water gagings and decoct 2 times, each 1 hour, collecting decoction, filter, filtrate is concentrated into the thick paste that within the scope of 85 ℃, relative density is 1.25.
6. the preparation method of a kind of Radix Astragali lalang grass rhizome Chinese yam chewable tablets according to claim 3, is characterized in that: every described of chewable tablets is 0.6g-3.5g.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310665473.9A CN103652556A (en) | 2013-12-11 | 2013-12-11 | Radix astragali, couchgrass root and rhizoma dioscoreae chewable tablets and preparation method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310665473.9A CN103652556A (en) | 2013-12-11 | 2013-12-11 | Radix astragali, couchgrass root and rhizoma dioscoreae chewable tablets and preparation method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103652556A true CN103652556A (en) | 2014-03-26 |
Family
ID=50292275
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310665473.9A Pending CN103652556A (en) | 2013-12-11 | 2013-12-11 | Radix astragali, couchgrass root and rhizoma dioscoreae chewable tablets and preparation method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103652556A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106727882A (en) * | 2016-11-30 | 2017-05-31 | 四川旭阳药业有限责任公司 | The method that microwave sterilization is carried out to the Radix Astragali |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1055877A (en) * | 1990-04-20 | 1991-11-06 | 国家医药管理局上海医药工业研究院 | The preparation method of Chinese medicine chewable tablet |
| CN1985946A (en) * | 2006-12-20 | 2007-06-27 | 北京润德康医药技术有限公司 | New preparing process for lung heat clearing and phlegm resolving preparation |
| CN101214014A (en) * | 2008-01-02 | 2008-07-09 | 南京农业大学 | Production technology of barley seedling powder and product thereof |
| CN102919437A (en) * | 2012-09-26 | 2013-02-13 | 厦门中药厂有限公司 | Health care composition for clearing lung and stomach and preparation method thereof |
-
2013
- 2013-12-11 CN CN201310665473.9A patent/CN103652556A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1055877A (en) * | 1990-04-20 | 1991-11-06 | 国家医药管理局上海医药工业研究院 | The preparation method of Chinese medicine chewable tablet |
| CN1985946A (en) * | 2006-12-20 | 2007-06-27 | 北京润德康医药技术有限公司 | New preparing process for lung heat clearing and phlegm resolving preparation |
| CN101214014A (en) * | 2008-01-02 | 2008-07-09 | 南京农业大学 | Production technology of barley seedling powder and product thereof |
| CN102919437A (en) * | 2012-09-26 | 2013-02-13 | 厦门中药厂有限公司 | Health care composition for clearing lung and stomach and preparation method thereof |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106727882A (en) * | 2016-11-30 | 2017-05-31 | 四川旭阳药业有限责任公司 | The method that microwave sterilization is carried out to the Radix Astragali |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103372169A (en) | Preparation for treating alcoholism and dispelling effects of alcohol | |
| CN104069333A (en) | Medicine for treating recurrent oral ulceration and preparation method thereof | |
| CN101518580A (en) | Pharmaceutical composition for clearing heat and releasing toxin as well as preparation method and application thereof | |
| CN103637202B (en) | Rhizoma dioscoreae-radix astragali-poria cocos chewable tablets and preparation method | |
| CN103652556A (en) | Radix astragali, couchgrass root and rhizoma dioscoreae chewable tablets and preparation method | |
| CN105379885A (en) | Moderate stomach-nourishing type ancient-prescription herbal tea | |
| CN103637045B (en) | Platycodon grandiflorum, radix polygonati officinalis and radix pseudostellariae chewable tablet and preparation method thereof | |
| CN103652904B (en) | Lily, bulbus fritillariae cirrhosae and rhizoma dioscoreae chewable tablets and preparation method | |
| CN103948133B (en) | Fevervine extract solution and preparation method thereof | |
| CN103652906B (en) | A kind of nourishing Yin and promoting production of body fluid radix rehmanniae recen chewable tablets and preparation method | |
| CN106616123A (en) | Health drink and making method thereof | |
| CN103652909A (en) | Chewable tablet containing dried orange peel, momordica grosvenori and Chinese yam and preparation method thereof | |
| CN103652900B (en) | Fructus perillae, radish seed and radix scrophulariae chewable tablets and preparation method | |
| CN106038988B (en) | It is a kind of for preventing and treating the natural plant extracts and its preparation of pneumoconiosis | |
| CN103637206A (en) | Yam chewable tablet for nourishing yin and clearing lung-heat and preparation method thereof | |
| CN103652558B (en) | A kind of GUANG Radix Notoginseng bletilla Chinese yam chewable tablet and preparation method | |
| CN104524256A (en) | Traditional Chinese medicine for treating viral pneumonia | |
| CN103652919B (en) | Fructus corni-lucid ganoderma-Chinese yam chewable tablet and preparation method thereof | |
| CN103461589A (en) | Food sleep-assisting tea granules for improving sleep | |
| CN103652902B (en) | Cordyceps sinensis, fructus lycii and Chinese yam chewing tablet and preparation method thereof | |
| CN108477394A (en) | A kind of prevention lamb infectiousness epidemic disease feed and preparation method thereof | |
| CN103637207A (en) | Chewable tablet of lilium brownie and radix asparagi and preparation method thereof | |
| CN1951494B (en) | Compound Chinese medicinal preparation for treating affection of external wind and cold and preparation method thereof | |
| CN1947779A (en) | Traditional Chinese medicine granules for treating infantile cough and its prepn. method | |
| CN1298377C (en) | Wheat seeding powder for preventing and treating insulin resisting syndrome and its preparation process |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C12 | Rejection of a patent application after its publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20140326 |