CN103652900B - Fructus perillae, radish seed and radix scrophulariae chewable tablets and preparation method - Google Patents
Fructus perillae, radish seed and radix scrophulariae chewable tablets and preparation method Download PDFInfo
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Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/20—Agglomerating; Granulating; Tabletting
- A23P10/28—Tabletting; Making food bars by compression of a dry powdered mixture
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The invention discloses fructus perillae, radish seed and radix scrophulariae chewable tablets which comprise the following components in parts by weight: 8-12 parts of rhizoma dioscoreae, 1-3 parts of fructus perillae, 1-3 parts of radish seed, 3-7 parts of radix scrophulariae, 1-3 parts of microcrystalline cellulose, 1-3 parts of lyophilized powder of royal jelly, 0.002-0.004 part of beta-cyclodextrine, 8-12 parts of starch, 0.001-0.003 part of isorhamnetin, 0.01-0.03 part of xylitol, 0.01-0.03 part of mannitol, 0.01-0.03 part of hydroxymethyl cellulose and 0.01-0.03 part of magnesium stearate. The fructus perillae, radish seed and radix scrophulariae chewable tablets disclosed by the invention have the functions of relieving cough and asthma, guiding qi downward and dissolving phlegm, nourishing yin and clearing lung heat and enhancing immunity, and are suitable for pulmonary emphysema with symptoms such as cough and asthma and qi counterflow, excessive and viscous phlegm, white phlegm with bubbles, thoracic fullness with discomfort, red tongue and little fluid and the like.
Description
Technical field
The invention belongs to nutritional health food field, be specially a kind of perilla seed radish seed radix scrophulariae chewable tablets and preparation method.
Background technology
The pathogenesis of chronic obstructive emphysema is agnogenio so far, is commonly considered as multifactor formation, comprise the decline of self resistance, infection, smoking, atmosphere pollution, occupational dusts, pernicious gas suck for a long time, allergy, weather cataclysm etc.Pathogenesis comprises bronchitis makes tube chamber obstruction, inflammatory destruction bronchium cartilago parietalis, leucocyte and macrophage release protease infringement lung tissue and alveolar wall capillary pressurized blood for reducing.Chronic obstructive emphysema belongs to traditional Chinese medicine the lung-distension category.This disease is based on the dificiency of the lung due to protracted disease, at lung, continues in sick position, affects spleen, kidney, prolonged illness and the heart.Outer heresy violates lung repeatedly, for a long time the then deficiency syndrome of the lung, tuberculosis and spleen, cause deficiency of both lung and spleen, the turbid interior life of phlegm, tuberculosis and kidney, kidney qi is feeble and exhausted, failure of qi transforming fluid, body fluid the moon turns to water drink, and Lung Qi deficiency can not promote the operation of painstaking effort, and hyperamization row of a specified duration is unsmooth, raw in hemostasis, water drink, blood stasis turbid to phlegm interact, transform mutually eventually.Characteristic of disease many genus asthenia in origin and asthenia in superficiality, Acute Exacerbation Period relatively marks reality, and Stationary phase is partial to this void.Symptomatic treatment in acute condition in treatment, radical treatment in chronic case.In compound injection of red sage root and Clary injection, the red sage root is promoting blood circulation and removing blood stasis, and relieving restlessness is calmed the nerves; Dalbergia wood fragrance is pungent alters, and regulates the flow of vital energy and has one's ideas straightened out.Modern pharmacological research shows, the red sage root has hemangiectasis, anti-freezing, prevent thrombosis and the effect such as to stimulate circulation, obviously can reduce pulmonary artery pressure, increase coronary artery blood supply, strengthen cardiac contractility ability, energy scavenging free radicals, improves cell hypoxia situation simultaneously, promotes cell metabolism.Therapy of combing traditional Chinese and Western medicine can improve symptom significantly, Shorten the Treatment Process, improves cure rate, reduces case fatality rate; Stationary phase periodic administration can enhanced machine body immunity function, reduces infection rate, reduces attack times, and delays impairment of pulmonary function speed.Observed result shows, therapy of combing traditional Chinese and Western medicine chronic obstructive emphysema effect is better than simple western medicine treatment, clinic application and popularization.
Summary of the invention
For above-mentioned situation, technical problem solved by the invention is to provide a kind of relieve coughing Zhichuan, pleasant dissolving phlegm, the perilla seed radish seed radix scrophulariae chewable tablets of enriching yin clearing lung-heat, develop immunitypty and preparation method, to solve the problem proposed in above-mentioned background technology.
For achieving the above object, the invention provides following technical scheme:
A kind of perilla seed radish seed radix scrophulariae chewable tablets, comprises following parts by weight ingredient: Chinese yam 8-12 part, perilla seed 1-3 part, radish seed 1-3 part, radix scrophulariae 3-7 part, microcrystalline cellulose 1-3 part, royal jelly freeze-dried powder 1-3 part, cycloheptaamylose 0.002-0.004 part, starch 8-12 part, Isorhamnetin 0.001-0.003 part, xylitol 0.01-0.03 part, sweet mellow wine 0.01-0.03 part, CMC 0.01-0.03 part, dolomol 0.01-0.03 part.
As preferably, described a kind of perilla seed radish seed radix scrophulariae chewable tablets, comprises following parts by weight ingredient: Chinese yam 10 parts, perilla seed 2 parts, radish seed 2 parts, radix scrophulariae 5 parts, microcrystalline cellulose 2 parts, royal jelly freeze-dried powder 2 parts, cycloheptaamylose 0.003 part, starch 10 parts, Isorhamnetin 0.002 part, xylitol 0.02 part, 0.02 part, sweet mellow wine, CMC 0.02 part, dolomol 0.02 part.
A preparation method for perilla seed radish seed radix scrophulariae chewable tablets, comprises the following steps:
(1) get fresh Chinese yam to clean, peeling is cleaned, put into stainless steel cylinder, add the water of raw material 3-6 times weight, within the scope of 30-50 DEG C, add 0.5% vitamin C colour protecting liquid soak 3-5 hour, adopt air drier again, hot blast temperature 70-75 DEG C, moisture is not had to Chinese yam surface, then this Chinese yam is passed through colloid mill, colloid mill operation condition is: the gap of adjustment colloid mill stator and rotor is 400-600 μm, colloid mill flow be 0.7-1 ton/hour, obtain Chinese yam wet-milling, carry out drying again, temperature is within the scope of 70-80 DEG C, dry 1-5 hour, obtain yam flour for subsequent use,
(2) raw material perilla seed is got, radish seed, radix scrophulariae is cleaned, boiling 1-3 time, filter, each water add quality be the 3-10 of material quality doubly, decocting time is 1-5 hour, merging filtrate, be concentrated into the clear cream that relative density within the scope of 50-100 DEG C is 1.00-1.50, add described clear paste volume 1-5 ethanol doubly, abundant stirring, leave standstill 4-20 hour, get supernatant, add butanone extraction 1-6 time, each butanone add volume be the 1-10 of the clear paste volume be extracted doubly, combining extraction liquid, reclaiming butanone and being concentrated into relative density within the scope of 50-100 DEG C is the thick paste of 1.00-1.50, above-mentioned thick paste is dry, pulverize and screening, obtain extract powder,
(3) get microcrystalline cellulose, cycloheptaamylose, Isorhamnetin, xylitol, sweet mellow wine, CMC, dolomol pulverize respectively, cross 120 mesh sieves respectively for subsequent use;
(4) extract powder in the yam flour in step (1), step (2) and starch are placed in mixer mixing 10-30 minute, again above-mentioned mixed powder is placed in micronizer to pulverize, be ground into the Ultramicro-powder of 5-8 μm, beta-schardinger dextrin-, Isorhamnetin is added to above-mentioned Ultramicro-powder, and fully mix, obtain mixed powder A;
(5) microcrystalline cellulose after above-mentioned pulverizing, xylitol, sweet mellow wine, CMC mixed with the mixed powder A in royal jelly freeze-dried powder, step (4) and stir, obtaining mixed powder B;
(6) the mixed powder B in step (5) is slowly added the ethanol water of wetting agent 80%, adjustment humidity of materials, makes softwood, the soft durometer standard of softwood can be agglomerating for pinching with hand, and light pressure is then fallen apart, and obtained softwood is carried out in comminutor granulation, cross 20 mesh sieves, obtain wet grain;
(7) wet grain is placed in temperature and carries out drying at the drying box of 50-65 DEG C, be dried to its water content below 5%, then be placed in airtight container temperature is cooled to 18-23 DEG C, obtain dried particles;
(8) in dried particles, add dolomol as lubricant, mix, be placed in tablet press machine compressing tablet;
(9) tablet suppressed adopts microwave sterilization, and the temperature of microwave is within the scope of 92-95 DEG C, and sterilization time is 3-8 minute, finally adopts lucifuge packaging, obtains perilla seed radish seed radix scrophulariae chewable tablets.
Get fresh Chinese yam in described step (1) to clean, peeling is cleaned, put into stainless steel cylinder, add the water of raw material 3 times of weight, within the scope of 30-50 DEG C, add 0.5% vitamin C colour protecting liquid soak 3 hours, adopt air drier again, hot blast temperature 75 DEG C, does not have moisture to Chinese yam surface, then this Chinese yam is passed through colloid mill, colloid mill operation condition is: the gap of adjustment colloid mill stator and rotor is 500 μm, colloid mill flow is 0.7 ton/hour, obtains Chinese yam wet-milling, then carries out drying, temperature is under 80 DEG C of conditions dry 5 hours, obtains yam flour.
Raw material perilla seed is got in described step (2), radish seed, radix scrophulariae is cleaned, boiling 3 times, filter, each water add 5 times that quality is material quality, decocting time is 1 hour, merging filtrate, be concentrated into the clear cream that relative density under 55 DEG C of conditions is 1.50, add the ethanol of described clear paste volume 5 times, abundant stirring, leave standstill 20 hours, get supernatant, add butanone and extract 2 times, each butanone add 6 times that volume is the clear paste volume be extracted, combining extraction liquid, reclaiming butanone and being concentrated into relative density within the scope of 80 DEG C is the thick paste of 1.10, above-mentioned thick paste is dry, pulverize and screening, obtain extract powder.
The every sheet of described chewable tablets is 0.6g-3.5g.
In sum, beneficial effect of the present invention:
The present invention has relieve coughing Zhichuan, pleasant dissolving phlegm, enriching yin clearing lung-heat, develop immunitypty.Be applicable to emphysema see cough breathe inverse, phlegm is many and sticky, phlegm look has foam, fullness sensation in chest discomfort, red tongue with a little fluid etc. in vain.
Detailed description of the invention
Below in conjunction with the embodiment of the present invention, be clearly and completely described the technical scheme in the embodiment of the present invention, obviously, described embodiment is only the present invention's part embodiment, instead of whole embodiments.Based on the embodiment in the present invention, those of ordinary skill in the art, not making the every other embodiment obtained under creative work prerequisite, belong to the scope of protection of the invention.
Embodiment 1
A kind of perilla seed radish seed radix scrophulariae chewable tablets, comprises following parts by weight ingredient: Chinese yam 8 parts, perilla seed 1 part, radish seed 1 part, radix scrophulariae 3 parts, microcrystalline cellulose 1 part, royal jelly freeze-dried powder 1 part, cycloheptaamylose 0.002 part, starch 8 parts, Isorhamnetin 0.001 part, xylitol 0.01 part, 0.01 part, sweet mellow wine, CMC 0.01 part, dolomol 0.01 part.
A preparation method for perilla seed radish seed radix scrophulariae chewable tablets, comprises the following steps:
(1) get fresh Chinese yam to clean, peeling is cleaned, put into stainless steel cylinder, add the water of raw material 3-6 times weight, within the scope of 30-50 DEG C, add 0.5% vitamin C colour protecting liquid soak 3-5 hour, adopt air drier again, hot blast temperature 70-75 DEG C, moisture is not had to Chinese yam surface, then this Chinese yam is passed through colloid mill, colloid mill operation condition is: the gap of adjustment colloid mill stator and rotor is 400-600 μm, colloid mill flow be 0.7-1 ton/hour, obtain Chinese yam wet-milling, carry out drying again, temperature is within the scope of 70-80 DEG C, dry 1-5 hour, obtain yam flour for subsequent use,
(2) raw material perilla seed is got, radish seed, radix scrophulariae is cleaned, boiling 1-3 time, filter, each water add quality be the 3-10 of material quality doubly, decocting time is 1-5 hour, merging filtrate, be concentrated into the clear cream that relative density within the scope of 50-100 DEG C is 1.00-1.50, add described clear paste volume 1-5 ethanol doubly, abundant stirring, leave standstill 4-20 hour, get supernatant, add butanone extraction 1-6 time, each butanone add volume be the 1-10 of the clear paste volume be extracted doubly, combining extraction liquid, reclaiming butanone and being concentrated into relative density within the scope of 50-100 DEG C is the thick paste of 1.00-1.50, above-mentioned thick paste is dry, pulverize and screening, obtain extract powder,
(3) get microcrystalline cellulose, cycloheptaamylose, Isorhamnetin, xylitol, sweet mellow wine, CMC, dolomol pulverize respectively, cross 120 mesh sieves respectively for subsequent use;
(4) extract powder in the yam flour in step (1), step (2) and starch are placed in mixer mixing 10-30 minute, again above-mentioned mixed powder is placed in micronizer to pulverize, be ground into the Ultramicro-powder of 5-8 μm, beta-schardinger dextrin-, Isorhamnetin is added to above-mentioned Ultramicro-powder, and fully mix, obtain mixed powder A;
(5) microcrystalline cellulose after above-mentioned pulverizing, xylitol, sweet mellow wine, CMC mixed with the mixed powder A in royal jelly freeze-dried powder, step (4) and stir, obtaining mixed powder B;
(6) the mixed powder B in step (5) is slowly added the ethanol water of wetting agent 80%, adjustment humidity of materials, makes softwood, the soft durometer standard of softwood can be agglomerating for pinching with hand, and light pressure is then fallen apart, and obtained softwood is carried out in comminutor granulation, cross 20 mesh sieves, obtain wet grain;
(7) wet grain is placed in temperature and carries out drying at the drying box of 50-65 DEG C, be dried to its water content below 5%, then be placed in airtight container temperature is cooled to 18-23 DEG C, obtain dried particles;
(8) in dried particles, add dolomol as lubricant, mix, be placed in tablet press machine compressing tablet;
(9) tablet suppressed adopts microwave sterilization, and the temperature of microwave is within the scope of 92-95 DEG C, and sterilization time is 3-8 minute, finally adopts lucifuge packaging, obtains perilla seed radish seed radix scrophulariae chewable tablets.By Chinese yam powder process in described step (1), specifically comprise the following steps:
Embodiment 2
A kind of perilla seed radish seed radix scrophulariae chewable tablets, comprises following parts by weight ingredient: Chinese yam 10 parts, perilla seed 2 parts, radish seed 2 parts, radix scrophulariae 5 parts, microcrystalline cellulose 2 parts, royal jelly freeze-dried powder 2 parts, cycloheptaamylose 0.003 part, starch 10 parts, Isorhamnetin 0.002 part, xylitol 0.02 part, 0.02 part, sweet mellow wine, CMC 0.02 part, dolomol 0.02 part.
A preparation method for perilla seed radish seed radix scrophulariae chewable tablets, comprises the following steps:
(1) get fresh Chinese yam to clean, peeling is cleaned, put into stainless steel cylinder, add the water of raw material 3-6 times weight, within the scope of 30-50 DEG C, add 0.5% vitamin C colour protecting liquid soak 3-5 hour, adopt air drier again, hot blast temperature 70-75 DEG C, moisture is not had to Chinese yam surface, then this Chinese yam is passed through colloid mill, colloid mill operation condition is: the gap of adjustment colloid mill stator and rotor is 400-600 μm, colloid mill flow be 0.7-1 ton/hour, obtain Chinese yam wet-milling, carry out drying again, temperature is within the scope of 70-80 DEG C, dry 1-5 hour, obtain yam flour for subsequent use,
(2) raw material perilla seed is got, radish seed, radix scrophulariae is cleaned, boiling 1-3 time, filter, each water add quality be the 3-10 of material quality doubly, decocting time is 1-5 hour, merging filtrate, be concentrated into the clear cream that relative density within the scope of 50-100 DEG C is 1.00-1.50, add described clear paste volume 1-5 ethanol doubly, abundant stirring, leave standstill 4-20 hour, get supernatant, add butanone extraction 1-6 time, each butanone add volume be the 1-10 of the clear paste volume be extracted doubly, combining extraction liquid, reclaiming butanone and being concentrated into relative density within the scope of 50-100 DEG C is the thick paste of 1.00-1.50, above-mentioned thick paste is dry, pulverize and screening, obtain extract powder,
(3) get microcrystalline cellulose, cycloheptaamylose, Isorhamnetin, xylitol, sweet mellow wine, CMC, dolomol pulverize respectively, cross 120 mesh sieves respectively for subsequent use;
(4) extract powder in the yam flour in step (1), step (2) and starch are placed in mixer mixing 10-30 minute, again above-mentioned mixed powder is placed in micronizer to pulverize, be ground into the Ultramicro-powder of 5-8 μm, beta-schardinger dextrin-, Isorhamnetin is added to above-mentioned Ultramicro-powder, and fully mix, obtain mixed powder A;
(5) microcrystalline cellulose after above-mentioned pulverizing, xylitol, sweet mellow wine, CMC mixed with the mixed powder A in royal jelly freeze-dried powder, step (4) and stir, obtaining mixed powder B;
(6) the mixed powder B in step (5) is slowly added the ethanol water of wetting agent 80%, adjustment humidity of materials, makes softwood, the soft durometer standard of softwood can be agglomerating for pinching with hand, and light pressure is then fallen apart, and obtained softwood is carried out in comminutor granulation, cross 20 mesh sieves, obtain wet grain;
(7) wet grain is placed in temperature and carries out drying at the drying box of 50-65 DEG C, be dried to its water content below 5%, then be placed in airtight container temperature is cooled to 18-23 DEG C, obtain dried particles;
(8) in dried particles, add dolomol as lubricant, mix, be placed in tablet press machine compressing tablet;
(9) tablet suppressed adopts microwave sterilization, and the temperature of microwave is within the scope of 92-95 DEG C, and sterilization time is 3-8 minute, finally adopts lucifuge packaging, obtains perilla seed radish seed radix scrophulariae chewable tablets.
Embodiment 3
A kind of perilla seed radish seed radix scrophulariae chewable tablets, comprises following parts by weight ingredient: Chinese yam 12 parts, perilla seed 3 parts, radish seed 3 parts, radix scrophulariae 7 parts, microcrystalline cellulose 3 parts, royal jelly freeze-dried powder 3 parts, cycloheptaamylose 0.004 part, starch 12 parts, Isorhamnetin 0.003 part, xylitol 0.03 part, 0.03 part, sweet mellow wine, CMC 0.03 part, dolomol 0.03 part.
A preparation method for perilla seed radish seed radix scrophulariae chewable tablets, comprises the following steps:
(1) get fresh Chinese yam to clean, peeling is cleaned, put into stainless steel cylinder, add the water of raw material 3-6 times weight, within the scope of 30-50 DEG C, add 0.5% vitamin C colour protecting liquid soak 3-5 hour, adopt air drier again, hot blast temperature 70-75 DEG C, moisture is not had to Chinese yam surface, then this Chinese yam is passed through colloid mill, colloid mill operation condition is: the gap of adjustment colloid mill stator and rotor is 400-600 μm, colloid mill flow be 0.7-1 ton/hour, obtain Chinese yam wet-milling, carry out drying again, temperature is within the scope of 70-80 DEG C, dry 1-5 hour, obtain yam flour for subsequent use,
(2) raw material perilla seed is got, radish seed, radix scrophulariae is cleaned, boiling 1-3 time, filter, each water add quality be the 3-10 of material quality doubly, decocting time is 1-5 hour, merging filtrate, be concentrated into the clear cream that relative density within the scope of 50-100 DEG C is 1.00-1.50, add described clear paste volume 1-5 ethanol doubly, abundant stirring, leave standstill 4-20 hour, get supernatant, add butanone extraction 1-6 time, each butanone add volume be the 1-10 of the clear paste volume be extracted doubly, combining extraction liquid, reclaiming butanone and being concentrated into relative density within the scope of 50-100 DEG C is the thick paste of 1.00-1.50, above-mentioned thick paste is dry, pulverize and screening, obtain extract powder,
(3) get microcrystalline cellulose, cycloheptaamylose, Isorhamnetin, xylitol, sweet mellow wine, CMC, dolomol pulverize respectively, cross 120 mesh sieves respectively for subsequent use;
(4) extract powder in the yam flour in step (1), step (2) and starch are placed in mixer mixing 10-30 minute, again above-mentioned mixed powder is placed in micronizer to pulverize, be ground into the Ultramicro-powder of 5-8 μm, beta-schardinger dextrin-, Isorhamnetin is added to above-mentioned Ultramicro-powder, and fully mix, obtain mixed powder A;
(5) microcrystalline cellulose after above-mentioned pulverizing, xylitol, sweet mellow wine, CMC mixed with the mixed powder A in royal jelly freeze-dried powder, step (4) and stir, obtaining mixed powder B;
(6) the mixed powder B in step (5) is slowly added the ethanol water of wetting agent 80%, adjustment humidity of materials, makes softwood, the soft durometer standard of softwood can be agglomerating for pinching with hand, and light pressure is then fallen apart, and obtained softwood is carried out in comminutor granulation, cross 20 mesh sieves, obtain wet grain;
(7) wet grain is placed in temperature and carries out drying at the drying box of 50-65 DEG C, be dried to its water content below 5%, then be placed in airtight container temperature is cooled to 18-23 DEG C, obtain dried particles;
(8) in dried particles, add dolomol as lubricant, mix, be placed in tablet press machine compressing tablet;
(9) tablet suppressed adopts microwave sterilization, and the temperature of microwave is within the scope of 92-95 DEG C, and sterilization time is 3-8 minute, finally adopts lucifuge packaging, obtains perilla seed radish seed radix scrophulariae chewable tablets.
To those skilled in the art, obviously the invention is not restricted to the details of above-mentioned one exemplary embodiment, and when not deviating from spirit of the present invention or essential characteristic, the present invention can be realized in other specific forms.Therefore, no matter from which point, all should embodiment be regarded as exemplary, and be nonrestrictive, scope of the present invention is limited by claims instead of above-mentioned explanation, and all changes be therefore intended in the implication of the equivalency by dropping on claim and scope are included in the present invention.
In addition, be to be understood that, although this description is described according to embodiment, but not each embodiment only comprises an independently technical scheme, this narrating mode of description is only for clarity sake, those skilled in the art should by description integrally, and the technical scheme in each embodiment also through appropriately combined, can form other embodiments that it will be appreciated by those skilled in the art that.
Claims (1)
1. a preparation method for perilla seed radish seed radix scrophulariae chewable tablets, is characterized in that: comprise the following steps:
(1) get fresh Chinese yam to clean, peeling is cleaned, put into stainless steel cylinder, add the water of raw material 3 times of weight, within the scope of 30-50 DEG C, add 0.5% vitamin C colour protecting liquid soak 3 hours, adopt air drier again, hot blast temperature 75 DEG C, does not have moisture to Chinese yam surface, then this Chinese yam is passed through colloid mill, colloid mill operation condition is: the gap of adjustment colloid mill stator and rotor is 500 μm, colloid mill flow is 0.7 ton/hour, obtains Chinese yam wet-milling, then carries out drying, temperature is under 80 DEG C of conditions dry 5 hours, obtains yam flour;
(2) raw material perilla seed is got, radish seed, radix scrophulariae is cleaned, boiling 3 times, filter, each water add 5 times that quality is material quality, decocting time is 1 hour, merging filtrate, be concentrated into the clear cream that relative density under 55 DEG C of conditions is 1.50, add the ethanol of described clear paste volume 5 times, abundant stirring, leave standstill 20 hours, get supernatant, add butanone and extract 2 times, each butanone add 6 times that volume is the clear paste volume be extracted, combining extraction liquid, reclaiming butanone and being concentrated into relative density within the scope of 80 DEG C is the thick paste of 1.10, above-mentioned thick paste is dry, pulverize and screening, obtain extract powder,
(3) get microcrystalline cellulose, cycloheptaamylose, Isorhamnetin, xylitol, sweet mellow wine, CMC, dolomol pulverize respectively, cross 120 mesh sieves respectively for subsequent use;
(4) extract powder in the yam flour in step (1), step (2) and starch are placed in mixer mixing 10-30 minute, again above-mentioned mixed powder is placed in micronizer to pulverize, be ground into the Ultramicro-powder of 5-8 μm, beta-schardinger dextrin-, Isorhamnetin is added to above-mentioned Ultramicro-powder, and fully mix, obtain mixed powder A;
(5) microcrystalline cellulose after above-mentioned pulverizing, xylitol, sweet mellow wine, CMC mixed with the mixed powder A in royal jelly freeze-dried powder, step (4) and stir, obtaining mixed powder B;
(6) the mixed powder B in step (5) is slowly added the ethanol water of wetting agent 80%, adjustment humidity of materials, makes softwood, the soft durometer standard of softwood can be agglomerating for pinching with hand, and light pressure is then fallen apart, and obtained softwood is carried out in comminutor granulation, cross 20 mesh sieves, obtain wet grain;
(7) wet grain is placed in temperature and carries out drying at the drying box of 50-65 DEG C, be dried to its water content below 5%, then be placed in airtight container temperature is cooled to 18-23 DEG C, obtain dried particles;
(8) in dried particles, add dolomol as lubricant, mix, be placed in tablet press machine compressing tablet;
(9) tablet suppressed adopts microwave sterilization, and the temperature of microwave is within the scope of 92-95 DEG C, and sterilization time is 3-8 minute, finally adopts lucifuge packaging, obtains perilla seed radish seed radix scrophulariae chewable tablets.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1055877A (en) * | 1990-04-20 | 1991-11-06 | 国家医药管理局上海医药工业研究院 | The preparation method of Chinese medicine chewable tablet |
| CN101214014A (en) * | 2008-01-02 | 2008-07-09 | 南京农业大学 | Production technology of barley seedling powder and product thereof |
| CN102511753A (en) * | 2012-01-16 | 2012-06-27 | 南京农业大学 | Process for preparing brassica vegetable seedling powder chewable tablets and brassica vegetable seedling powder chewable tablet product |
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| CN1055877A (en) * | 1990-04-20 | 1991-11-06 | 国家医药管理局上海医药工业研究院 | The preparation method of Chinese medicine chewable tablet |
| CN101214014A (en) * | 2008-01-02 | 2008-07-09 | 南京农业大学 | Production technology of barley seedling powder and product thereof |
| CN102511753A (en) * | 2012-01-16 | 2012-06-27 | 南京农业大学 | Process for preparing brassica vegetable seedling powder chewable tablets and brassica vegetable seedling powder chewable tablet product |
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