CN103623354A - Traditional Chinese medicinal preparation for treating retroperitoneal follicular dendritic cell sarcoma - Google Patents
Traditional Chinese medicinal preparation for treating retroperitoneal follicular dendritic cell sarcoma Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicinal preparation for treating retroperitoneal follicular dendritic cell sarcoma. The traditional Chinese medicinal preparation is prepared from the following raw materials in parts by weight: 15-30 parts of hedyotis diffusa, 15-30 parts of herba patriniae, 15-30 parts of fructus forsythiae, 15-30 parts of dandelion, 10-20 parts of rhizoma curcumae, 10-20 parts of salviae miltiorrhizae, 10-20 parts of curcuma aromatica, 10-20 parts of rhizoma corydalis, 5-30 parts of pleione bulbocodioides, 15-30 parts of oysters, 5-30 parts of selfheal, 15-30 parts of carapax trionycis, 12-20 parts of poria cocos, 12-20 parts of atractylodes macrocephala koidz, 12-25 parts of angelica sinensis, 12-25 parts of yams and 12-25 parts of medlars. According to the traditional Chinese medicinal preparation disclosed by the invention, the hedyotis diffusa, the herba patriniae, the fructus forsythiae and the dandelion can clear heat and detoxify; the rhizoma curcumae, the salviae miltiorrhizae, the curcuma aromatica and the rhizoma corydalis can activate blood circulation to dissipate blood stasis; the pleione bulbocodioides, the oysters, the selfheal and the carapax trionycis can soften hard lumps and dispel nodes; the poria cocos, the atractylodes macrocephala koidz, the angelica sinensis, the yams and the medlars can strengthen and consolidate body resistance, tonify spleen and eliminate dampness; a traditional Chinese physician thinks that the sarcoma is mostly resulted from damp phlegm coagulation and is suitable to be treated by tonifying the spleen, eliminating dampness, reducing phlegm and resolving masses, so that multiple medicines are mixed in the preparation; the effect of treating the retroperitoneal follicular dendritic cell sarcoma is outstanding.
Description
Technical field
The present invention relates to Chinese medicine technical field, be specifically related to a kind of Chinese medicine preparation for the treatment of Follicular Dendritic Cell Sarcoma after peritoneum.
Background technology
After peritoneum, Follicular Dendritic Cell Sarcoma is that a class morphology is the tumprigenicity propagation that presents follicular dendritic cell feature in fusiformis or oval-shaped cell and phenotype.Age distribution is extensive, and majority is adult, and gender is suitable.Tumor cell is generally expressed the phenotype of non-tumor follicular dendritic cell, and biological behaviour inertia, more as the sarcoma of low potential malignancy.In < < prescriptions worth thousand gold > >, record: " sarcoma is not treated, and that treats kills a person, double cautious ", pointed out that sarcoma grade malignancy is high, poor prognosis.Modern medicine be take radical excision as main to primary disease in treatment, is aided with Radiotherapy chemotherapy, but controls rear recurrence and the rate of transform is high, survival rate is low, and prognosis is severe, and 40%～50% case there will be local recurrence.There is the shortcomings such as cost is high, toxic and side effects large, weak curative effect in Drug therapy at present.Up to now not yet there is Follicular Dendritic Cell Sarcoma after treatment peritoneum to have the medicine of satisfactory effect both at home and abroad.
Summary of the invention
For above-mentioned prior art, the invention provides a kind of Chinese medicine preparation for the treatment of Follicular Dendritic Cell Sarcoma after peritoneum.
The present invention is achieved by the following technical solutions:
Treating a Chinese medicine preparation for Follicular Dendritic Cell Sarcoma after peritoneum, is that the crude drug by following weight portion is prepared from: 15～30 parts of Herba Hedyotidis Diffusaes, 15～30 parts of Herba Patriniae, 15～30 parts of Fructus Forsythiaes, 15～30 parts of Herba Taraxacis, 10～20 parts of Rhizoma Curcumae, 10～20 parts of Radix Salviae Miltiorrhizaes, 10～20 parts of Radix Curcumaes, 10～20 parts of Rhizoma Corydalis, 5～30 parts of Pseudobulbus Cremastrae Seu Pleioness, 15～30 parts of Concha Ostreaes, 5～30 parts of Spica Prunellaes, 15～30 parts of Carapax Trionycis, 12～20 parts, Poria, 12～20 parts of the Rhizoma Atractylodis Macrocephalaes, 12～25 parts of Radix Angelicae Sinensis, 12～25 parts of Rhizoma Dioscoreaes, 12～25 parts of Fructus Lycii.
Preferably, be that crude drug by following weight portion is prepared from: 25 parts of Herba Hedyotidis Diffusaes, 22 parts of Herba Patriniae, 23 parts of Fructus Forsythiaes, 22 parts of Herba Taraxacis, 20 parts of Rhizoma Curcumae, 18 parts of Radix Salviae Miltiorrhizaes, 16 parts of Radix Curcumaes, 16 parts of Rhizoma Corydalis, 25 parts of Pseudobulbus Cremastrae Seu Pleioness, 22 parts of Concha Ostreaes, 20 parts of Spica Prunellaes, 16 parts of Carapax Trionycis, 18 parts, Poria, 16 parts of the Rhizoma Atractylodis Macrocephalaes, 22 parts of Radix Angelicae Sinensis, 22 parts of Rhizoma Dioscoreaes, 20 parts of Fructus Lycii.
Described a kind of preparation method for the treatment of the Chinese medicine preparation of Follicular Dendritic Cell Sarcoma after peritoneum, step is as follows:
(1) get Herba Hedyotidis Diffusae, Herba Patriniae, Fructus Forsythiae, Herba Taraxaci, Poria, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis, Rhizoma Dioscoreae, Fructus Lycii nine taste medical materials, pulverize, mix, conventional water boiling and extraction 2～4 hours, filters to get filtrate, simmer down to thick paste, and proportion is 1.25～1.32, standby;
(2) get Rhizoma Curcumae, Radix Salviae Miltiorrhizae, Radix Curcumae, Rhizoma Corydalis, Pseudobulbus Cremastrae Seu Pleiones, Spica Prunellae Six-element medical material, pulverize, mix, conventional water boiling and extraction 2～4 hours, filters to get filtrate, simmer down to thick paste, and proportion is 1.25～1.32, standby;
(3) get Concha Ostreae, Carapax Trionycis, pulverize, the alcohol reflux that is 50～75% by volumetric concentration 1～3 hour, reclaims ethanol and obtains medicinal liquid, simmer down to thick paste, and proportion is 1.25～1.32, standby;
(4) above-mentioned three kinds of thick pastes are mixed, mix, obtain;
Or: above-mentioned three kinds of thick pastes are mixed, mix, add appropriate amount of starch or dextrin, after vacuum drying or spraying are dry, add suitable conventional adjuvant to granulate, granulation agent, obtains;
Or: above-mentioned three kinds of thick pastes are mixed, mix, make ball shape, obtain.
Described step (1) (2) (3) is only form of presentation, there is no the difference of sequencing.
The property of medicine is analyzed:
Herba Hedyotidis Diffusae: its Chinese patent medicine bitter in the mouth, light, cold in nature.Main effect is heat-clearing and toxic substances removing, medicinal powder for relieving pain knot, promoting urination to remove dampness.Outstanding kind treatment all kinds inflammation.In clinical practice, if find, Herba Hedyotidis Diffusae compatibility is proper, can treat various diseases.
Herba Patriniae: pungent, bitter, cool.Enter stomach, large intestine, Liver Channel.Heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus, blood circulation promoting competent silt.For acute appendicitis, lung abscess and sore and toxic, the breast abdomen pain due to the excess-heat stasis of blood is stagnant, the diseases such as the stagnant stomachache of the stasis of blood in puerperal.
Fructus Forsythiae: bitter in the mouth, is slightly cold.Return lung, the heart, gallbladder meridian.Heat-clearing and toxic substances removing, cures mainly calentura from the beginning of, anemopyretic cold, and heating is vexed, laryngopharynx swelling and pain, acute nephritis etc.
Herba Taraxaci: sweet, micro-hardship, cold.Heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation.Enter spleen, stomach, kidney three warps.There are the effects such as diuresis, cathartic, jaundice eliminating subcutaneous ulcer, function of gallbladder promoting.
Rhizoma Curcumae: pungent, bitter, temperature.Return liver, spleen channel.Removing blood stasis, promoting the circulation of QI to relieve pain.For lump in the abdomen mass in the abdomen, blood stasis amenorrhea, food stagnation distending pain etc.
Radix Salviae Miltiorrhizae: bitter in the mouth, cold nature.Energy blood circulation promoting and blood stasis dispelling, removing heat from blood, calms the nerves.For menoxenia due to blood stasis, dysmenorrhea, amenorrhea, the stagnant stomachache of the stasis of blood in puerperal; Angina pectoris, atherosclerosis; Chronic hepatitis, liver cirrhosis, abdominal masses or tumor; Chronic cardiopulmonary disease, bronchial asthma; Blood failing to tonify the heart or heart-fire are partially high, palpitation and restlessness, vexed insomnia.
Radix Curcumae: pungent, bitter, cold.Return liver, the heart, lung meridian.Promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, the removing heat from blood that clears away heart-fire, promoting the function of the gallbladder to alleviate jaundice.
Rhizoma Corydalis: warm in nature, acrid in the mouth, hardship.Enter the heart, liver, spleen channel, have invigorate blood circulation, the effect of circulation of qi promoting, pain relieving.Its analgesic effect is remarkable, and site of action is extensive, and lasting and avirulence.
Pseudobulbus Cremastrae Seu Pleiones: bitter, micro-pungent, cool.Dispersing swelling and dissipating binds, reduces phlegm, heat-clearing and toxic substances removing.
Concha Ostreae: salty, be slightly cold; Return liver, gallbladder, kidney channel.Hard masses softening and resolving.By the sucutaneous nodule of controlling phlegm-fire pent-up, scrofula, goiter etc.
Spica Prunellae: bitter, acrid, cold.Enter liver, gallbladder meridian.Mass dissipating and swelling eliminating: control scrofula, goiter, acute mastitis and swell and ache.
Carapax Trionycis: salty, cold.Return liver, kidney channel.Nourishing YIN for suppressing the hyperactive YANG, hard masses softening and resolving, brings down a fever except steaming.For fever due to yin deficiency, consumptive fever hectic fever due to YIN-deficiency, stirring-up of pathogenic wind in the interior resulting from deficiency, amenorrhea ， WEIJIA, chronic malaria malaria with splenomegaly.
Poria: in the carcinoma such as the clinical conventional treatment esophageal carcinoma, gastric cancer, hepatocarcinoma, nasopharyngeal carcinoma, carcinoma of tongue, breast carcinoma, bladder cancer, pulmonary carcinoma, ulcer melanoma, belong in insufficiency of the spleen leading to overabundance of dampness, phlegm retention stop, damp and hot heap soil or fertilizer over and around the roots knot person.
The Rhizoma Atractylodis Macrocephalae: bitter, sweet, temperature.Return spleen, stomach warp.Air making-up and spleen enlivening, dampness diuretic, hidroschesis, antiabortive.
Radix Angelicae Sinensis: sweet in the mouth; Pungent; Bitter; Warm in nature.Return liver; The heart; Spleen channel.Cure mainly all cards of blood deficiency; Menoxenia; Amenorrhea; Dysmenorrhea; Lump in the abdomen knot is poly-; Metrorrhagia; Asthenia cold abdominalgia; Flaccidity syndrome and arthralgia syndrome; Numbness of the skin; Dryness of the intestine dyschezia; Heavy after bloody dysentery; Ulcer sores; Injury from falling down.
Rhizoma Dioscoreae: sweet, flat.Strengthening the spleen and stomach, lung benefiting kidney, tonify deficiency are won.Control anorexia and loose stool, asthenia, breath with cough, frequent micturition, leukorrhagia, quench one's thirst.
Fructus Lycii: sweet, flat.Nourishing the liver, nourishing kidney, lung moistening.
In this preparation, Herba Hedyotidis Diffusae, Herba Patriniae, Fructus Forsythiae, Herba Taraxaci can heat-clearing and toxic substances removing, Rhizoma Curcumae, Radix Salviae Miltiorrhizae, Radix Curcumae, Rhizoma Corydalis can blood circulation promoting and blood stasis dispelling, Pseudobulbus Cremastrae Seu Pleiones, Concha Ostreae, Spica Prunellae, Carapax Trionycis can hard masses softening and resolving, Poria, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis, Rhizoma Dioscoreae, Fructus Lycii strengthening the body resistance, invigorating the spleen to clear away damp pathogen, and the traditional Chinese medical science thinks, sarcoma is many because of due to damp-phlegm condenses, control suitable invigorating the spleen to clear away damp pathogen, dissipating phlegm and resolving masses, so in this formula, all medicine compatibilities, after treatment peritoneum, Follicular Dendritic Cell Sarcoma effect is remarkable.
The material that makes up a prescription in the present invention is all used natural Chinese herbal medicine, and material is easily got, and formula and preparation method are simple, prepare consumption cost cheap, take therapeutic effect good, and drug price is cheap.
The specific embodiment
Below in conjunction with embodiment, the present invention is further illustrated.
Embodiment 1: a kind of Chinese medicine preparation for the treatment of Follicular Dendritic Cell Sarcoma after peritoneum
Formula is: 25 grams of Herba Hedyotidis Diffusaes, 22 grams of Herba Patriniae, 23 grams of Fructus Forsythiaes, 22 grams of Herba Taraxacis, 20 grams of Rhizoma Curcumae, 18 grams of Radix Salviae Miltiorrhizaes, 16 grams of Radix Curcumaes, 16 grams of Rhizoma Corydalis, 25 grams of Pseudobulbus Cremastrae Seu Pleioness, 22 grams of Concha Ostreaes, 20 grams of Spica Prunellaes, 16 grams of Carapax Trionycis, 18 grams, Poria, 16 grams of the Rhizoma Atractylodis Macrocephalaes, 22 grams of Radix Angelicae Sinensis, 22 grams of Rhizoma Dioscoreaes, 20 grams of Fructus Lycii.
Preparation method is: (1) gets Herba Hedyotidis Diffusae, Herba Patriniae, Fructus Forsythiae, Herba Taraxaci, Poria, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis, Rhizoma Dioscoreae, Fructus Lycii nine taste medical materials, pulverizes, and mixes, conventional water boiling and extraction 3 hours, filters to get filtrate, simmer down to thick paste, proportion is 1.25～1.32, standby;
(2) get Rhizoma Curcumae, Radix Salviae Miltiorrhizae, Radix Curcumae, Rhizoma Corydalis, Pseudobulbus Cremastrae Seu Pleiones, Spica Prunellae Six-element medical material, pulverize, mix, conventional water boiling and extraction 3 hours, filters to get filtrate, simmer down to thick paste, and proportion is 1.25～1.32, standby;
(3) get Concha Ostreae, Carapax Trionycis, pulverize, the alcohol reflux that is 50～75% by volumetric concentration 1.5 hours, reclaims ethanol and obtains medicinal liquid, simmer down to thick paste, and proportion is 1.25～1.32, standby;
(4) above-mentioned three kinds of thick pastes are mixed, mix, obtain.
Embodiment 2: a kind of Chinese medicine preparation for the treatment of Follicular Dendritic Cell Sarcoma after peritoneum
Formula is: 15 grams of Herba Hedyotidis Diffusaes, 15 grams of Herba Patriniae, 15 grams of Fructus Forsythiaes, 15 grams of Herba Taraxacis, 10 grams of Rhizoma Curcumae, 10 grams of Radix Salviae Miltiorrhizaes, 10 grams of Radix Curcumaes, 10 grams of Rhizoma Corydalis, 5 grams of Pseudobulbus Cremastrae Seu Pleioness, 15 grams of Concha Ostreaes, 5 grams of Spica Prunellaes, 15 grams of Carapax Trionycis, 12 grams, Poria, 12 grams of the Rhizoma Atractylodis Macrocephalaes, 12 grams of Radix Angelicae Sinensis, 12 grams of Rhizoma Dioscoreaes, 12 grams of Fructus Lycii.
Preparation method is: (1) gets Herba Hedyotidis Diffusae, Herba Patriniae, Fructus Forsythiae, Herba Taraxaci, Poria, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis, Rhizoma Dioscoreae, Fructus Lycii nine taste medical materials, pulverizes, and mixes, conventional water boiling and extraction 2 hours, filters to get filtrate, simmer down to thick paste, proportion is 1.25～1.32, standby;
(2) get Rhizoma Curcumae, Radix Salviae Miltiorrhizae, Radix Curcumae, Rhizoma Corydalis, Pseudobulbus Cremastrae Seu Pleiones, Spica Prunellae Six-element medical material, pulverize, mix, conventional water boiling and extraction 2 hours, filters to get filtrate, simmer down to thick paste, and proportion is 1.25～1.32, standby;
(3) get Concha Ostreae, Carapax Trionycis, pulverize, the alcohol reflux that is 50～75% by volumetric concentration 1 hour, reclaims ethanol and obtains medicinal liquid, simmer down to thick paste, and proportion is 1.25～1.32, standby;
(4) above-mentioned three kinds of thick pastes are mixed, mix, add appropriate amount of starch or dextrin, after vacuum drying or spraying are dry, add suitable conventional adjuvant to granulate, granulation agent, obtains.
Embodiment 3: a kind of Chinese medicine preparation for the treatment of Follicular Dendritic Cell Sarcoma after peritoneum
Formula is: 30 grams of Herba Hedyotidis Diffusaes, 30 grams of Herba Patriniae, 30 grams of Fructus Forsythiaes, 30 grams of Herba Taraxacis, 20 grams of Rhizoma Curcumae, 20 grams of Radix Salviae Miltiorrhizaes, 20 grams of Radix Curcumaes, 20 grams of Rhizoma Corydalis, 30 grams of Pseudobulbus Cremastrae Seu Pleioness, 30 grams of Concha Ostreaes, 30 grams of Spica Prunellaes, 30 grams of Carapax Trionycis, 20 grams, Poria, 20 grams of the Rhizoma Atractylodis Macrocephalaes, 25 grams of Radix Angelicae Sinensis, 25 grams of Rhizoma Dioscoreaes, 25 grams of Fructus Lycii.
Preparation method is: (1) gets Herba Hedyotidis Diffusae, Herba Patriniae, Fructus Forsythiae, Herba Taraxaci, Poria, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis, Rhizoma Dioscoreae, Fructus Lycii nine taste medical materials, pulverizes, and mixes, conventional water boiling and extraction 4 hours, filters to get filtrate, simmer down to thick paste, proportion is 1.25～1.32, standby;
(2) get Rhizoma Curcumae, Radix Salviae Miltiorrhizae, Radix Curcumae, Rhizoma Corydalis, Pseudobulbus Cremastrae Seu Pleiones, Spica Prunellae Six-element medical material, pulverize, mix, conventional water boiling and extraction 4 hours, filters to get filtrate, simmer down to thick paste, and proportion is 1.25～1.32, standby;
(3) get Concha Ostreae, Carapax Trionycis, pulverize, the alcohol reflux that is 50～75% by volumetric concentration 3 hours, reclaims ethanol and obtains medicinal liquid, simmer down to thick paste, and proportion is 1.25～1.32, standby;
(4) above-mentioned three kinds of thick pastes are mixed, mix, make ball shape, obtain.
Embodiment 4: a kind of Chinese medicine preparation for the treatment of Follicular Dendritic Cell Sarcoma after peritoneum
Formula is: 20 grams of Herba Hedyotidis Diffusaes, 20 grams of Herba Patriniae, 20 grams of Fructus Forsythiaes, 20 grams of Herba Taraxacis, 15 grams of Rhizoma Curcumae, 14 grams of Radix Salviae Miltiorrhizaes, 13 grams of Radix Curcumaes, 14 grams of Rhizoma Corydalis, 15 grams of Pseudobulbus Cremastrae Seu Pleioness, 20 grams of Concha Ostreaes, 15 grams of Spica Prunellaes, 20 grams of Carapax Trionycis, 15 grams, Poria, 14 grams of the Rhizoma Atractylodis Macrocephalaes, 18 grams of Radix Angelicae Sinensis, 18 grams of Rhizoma Dioscoreaes, 16 grams of Fructus Lycii.
Preparation method is: (1) gets Herba Hedyotidis Diffusae, Herba Patriniae, Fructus Forsythiae, Herba Taraxaci, Poria, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis, Rhizoma Dioscoreae, Fructus Lycii nine taste medical materials, pulverizes, and mixes, conventional water boiling and extraction 3 hours, filters to get filtrate, simmer down to thick paste, proportion is 1.25～1.32, standby;
(2) get Rhizoma Curcumae, Radix Salviae Miltiorrhizae, Radix Curcumae, Rhizoma Corydalis, Pseudobulbus Cremastrae Seu Pleiones, Spica Prunellae Six-element medical material, pulverize, mix, conventional water boiling and extraction 3 hours, filters to get filtrate, simmer down to thick paste, and proportion is 1.25～1.32, standby;
(3) get Concha Ostreae, Carapax Trionycis, pulverize, the alcohol reflux that is 50～75% by volumetric concentration 1.5 hours, reclaims ethanol and obtains medicinal liquid, simmer down to thick paste, and proportion is 1.25～1.32, standby;
(4) above-mentioned three kinds of thick pastes are mixed, mix, add appropriate amount of starch or dextrin, after vacuum drying or spraying are dry, add suitable conventional adjuvant to granulate, granulation agent, obtains.
Embodiment 5: a kind of Chinese medicine preparation for the treatment of Follicular Dendritic Cell Sarcoma after peritoneum
Formula is: 28 grams of Herba Hedyotidis Diffusaes, 25 grams of Herba Patriniae, 25 grams of Fructus Forsythiaes, 26 grams of Herba Taraxacis, 18 grams of Rhizoma Curcumae, 20 grams of Radix Salviae Miltiorrhizaes, 18 grams of Radix Curcumaes, 20 grams of Rhizoma Corydalis, 28 grams of Pseudobulbus Cremastrae Seu Pleioness, 25 grams of Concha Ostreaes, 24 grams of Spica Prunellaes, 24 grams of Carapax Trionycis, 20 grams, Poria, 18 grams of the Rhizoma Atractylodis Macrocephalaes, 23 grams of Radix Angelicae Sinensis, 24 grams of Rhizoma Dioscoreaes, 23 grams of Fructus Lycii.
Compound method is: (1) gets Herba Hedyotidis Diffusae, Herba Patriniae, Fructus Forsythiae, Herba Taraxaci, Poria, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis, Rhizoma Dioscoreae, Fructus Lycii nine taste medical materials, pulverizes, and mixes, conventional water boiling and extraction 4 hours, filters to get filtrate, simmer down to thick paste, proportion is 1.25～1.32, standby;
(2) get Rhizoma Curcumae, Radix Salviae Miltiorrhizae, Radix Curcumae, Rhizoma Corydalis, Pseudobulbus Cremastrae Seu Pleiones, Spica Prunellae Six-element medical material, pulverize, mix, conventional water boiling and extraction 4 hours, filters to get filtrate, simmer down to thick paste, and proportion is 1.25～1.32, standby;
(3) get Concha Ostreae, Carapax Trionycis, pulverize, the alcohol reflux that is 50～75% by volumetric concentration 3 hours, reclaims ethanol and obtains medicinal liquid, simmer down to thick paste, and proportion is 1.25～1.32, standby;
(4) above-mentioned three kinds of thick pastes are mixed, mix, make ball shape, obtain.
Clinical data:
Case selection: 60 routine patients, at 30～60 years old age, 45 years old mean age, all patients all meet the diagnostic criteria of Follicular Dendritic Cell Sarcoma after peritoneum, select at random 30 examples as test group, and remaining 30 examples is matched group.
Curative effect judging standard:
Cure: after treatment, tumor disappears, without recurrence.
Effective: after treatment, tumor section disappears or dwindles.
Invalid: tumor section does not dwindle, or continue to increase.
Therapeutic scheme:
1, oral Chinese medicine preparation for the treatment of group, 1 dose of every day (medicine prepared by the formula ratio of embodiment 1).Divide and sooner or later respectively take after mixing it with water once, 20d is a course for the treatment of.
2, after matched group carries out peritoneum, Follicular Dendritic Cell Sarcoma is peeled off operation.
3, interpretation of result: after 3 courses for the treatment of, treatment group is cured 10 examples, effective 16 examples, total effective rate is in 86.7%, 6～12 months following up a case by regular visits to, and does not find rebound phenomenon; Matched group is cured 12 examples, and effective 8 examples, in the following up a case by regular visits to of total effective rate 66.7%, 6～12 months, are found 4 routine Patients on Recurrences, and therefore, treatment group curative effect is obviously better than matched group, and medication has no side effect and irritated case occurs.
Claims (3)
1. a Chinese medicine preparation for the treatment of Follicular Dendritic Cell Sarcoma after peritoneum, it is characterized in that, be that the crude drug by following weight portion is prepared from: 15～30 parts of Herba Hedyotidis Diffusaes, 15～30 parts of Herba Patriniae, 15～30 parts of Fructus Forsythiaes, 15～30 parts of Herba Taraxacis, 10～20 parts of Rhizoma Curcumae, 10～20 parts of Radix Salviae Miltiorrhizaes, 10～20 parts of Radix Curcumaes, 10～20 parts of Rhizoma Corydalis, 5～30 parts of Pseudobulbus Cremastrae Seu Pleioness, 15～30 parts of Concha Ostreaes, 5～30 parts of Spica Prunellaes, 15～30 parts of Carapax Trionycis, 12～20 parts, Poria, 12～20 parts of the Rhizoma Atractylodis Macrocephalaes, 12～25 parts of Radix Angelicae Sinensis, 12～25 parts of Rhizoma Dioscoreaes, 12～25 parts of Fructus Lycii.
2. a kind of Chinese medicine preparation for the treatment of Follicular Dendritic Cell Sarcoma after peritoneum as claimed in claim 1, it is characterized in that, be that the crude drug by following weight portion is prepared from: 25 parts of Herba Hedyotidis Diffusaes, 22 parts of Herba Patriniae, 23 parts of Fructus Forsythiaes, 22 parts of Herba Taraxacis, 20 parts of Rhizoma Curcumae, 18 parts of Radix Salviae Miltiorrhizaes, 16 parts of Radix Curcumaes, 16 parts of Rhizoma Corydalis, 25 parts of Pseudobulbus Cremastrae Seu Pleioness, 22 parts of Concha Ostreaes, 20 parts of Spica Prunellaes, 16 parts of Carapax Trionycis, 18 parts, Poria, 16 parts of the Rhizoma Atractylodis Macrocephalaes, 22 parts of Radix Angelicae Sinensis, 22 parts of Rhizoma Dioscoreaes, 20 parts of Fructus Lycii.
3. a kind of preparation method for the treatment of the Chinese medicine preparation of Follicular Dendritic Cell Sarcoma after peritoneum claimed in claim 1, it is characterized in that, step is as follows: (1) gets Herba Hedyotidis Diffusae, Herba Patriniae, Fructus Forsythiae, Herba Taraxaci, Poria, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis, Rhizoma Dioscoreae, Fructus Lycii nine taste medical materials, pulverize, mix conventional water boiling and extraction 2～4 hours, filter to get filtrate, simmer down to thick paste, proportion is 1.25～1.32, standby;
(2) get Rhizoma Curcumae, Radix Salviae Miltiorrhizae, Radix Curcumae, Rhizoma Corydalis, Pseudobulbus Cremastrae Seu Pleiones, Spica Prunellae Six-element medical material, pulverize, mix, conventional water boiling and extraction 2～4 hours, filters to get filtrate, simmer down to thick paste, and proportion is 1.25～1.32, standby;
(3) get Concha Ostreae, Carapax Trionycis, pulverize, the alcohol reflux that is 50～75% by volumetric concentration 1～3 hour, reclaims ethanol and obtains medicinal liquid, simmer down to thick paste, and proportion is 1.25～1.32, standby;
(4) above-mentioned three kinds of thick pastes are mixed, mix, obtain;
Or: above-mentioned three kinds of thick pastes are mixed, mix, add appropriate amount of starch or dextrin, after vacuum drying or spraying are dry, add suitable conventional adjuvant to granulate, granulation agent, obtains;
Or: above-mentioned three kinds of thick pastes are mixed, mix, make ball shape, obtain;
Described step (1) (2) (3) is only form of presentation, there is no the difference of sequencing.
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| CN201310659831.5A CN103623354B (en) | 2013-12-09 | 2013-12-09 | Traditional Chinese medicinal preparation for treating retroperitoneal follicular dendritic cell sarcoma |
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| CN105456444A (en) * | 2015-12-03 | 2016-04-06 | 刘彩虹 | Chinese herbal preparation for treating melanoma and preparation method and application thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1679769A (en) * | 2005-01-04 | 2005-10-12 | 高和平 | Chinese medicine composition for treating cancer |
| CN101612360A (en) * | 2009-07-17 | 2009-12-30 | 肖嘉惠 | The medicine of treatment hepatitis, liver cirrhosis, hepatocarcinoma |
| CN102772745A (en) * | 2012-08-21 | 2012-11-14 | 卢速江 | Chinese medicinal preparation for treating cancer and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1679769A (en) * | 2005-01-04 | 2005-10-12 | 高和平 | Chinese medicine composition for treating cancer |
| CN101612360A (en) * | 2009-07-17 | 2009-12-30 | 肖嘉惠 | The medicine of treatment hepatitis, liver cirrhosis, hepatocarcinoma |
| CN102772745A (en) * | 2012-08-21 | 2012-11-14 | 卢速江 | Chinese medicinal preparation for treating cancer and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 张志远: "常见癌症与中药调治", 《辽宁中医杂志》, vol. 21, no. 6, 30 June 1994 (1994-06-30), pages 248 - 250 * |
Cited By (1)
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| CN105456444A (en) * | 2015-12-03 | 2016-04-06 | 刘彩虹 | Chinese herbal preparation for treating melanoma and preparation method and application thereof |
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