CN103608661B - 用于样本照明的方法、系统和装置 - Google Patents

用于样本照明的方法、系统和装置 Download PDF

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Publication number
CN103608661B
CN103608661B CN201280021684.2A CN201280021684A CN103608661B CN 103608661 B CN103608661 B CN 103608661B CN 201280021684 A CN201280021684 A CN 201280021684A CN 103608661 B CN103608661 B CN 103608661B
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China
Prior art keywords
array
light
light sources
test
light source
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CN201280021684.2A
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English (en)
Chinese (zh)
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CN103608661A (zh
Inventor
F.克鲁夫卡
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Siemens Healthcare Diagnostics Inc
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Siemens Healthcare Diagnostics Inc
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J1/00—Photometry, e.g. photographic exposure meter
    • G01J1/42—Photometry, e.g. photographic exposure meter using electric radiation detectors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02—Details
    • G01J3/10—Arrangements of light sources specially adapted for spectrometry or colorimetry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum
    • G01J3/42—Absorption spectrometry; Double beam spectrometry; Flicker spectrometry; Reflection spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N2021/6417—Spectrofluorimetric devices
    • G01N2021/6419—Excitation at two or more wavelengths
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N2021/6417—Spectrofluorimetric devices
    • G01N2021/6421—Measuring at two or more wavelengths
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N2021/6463—Optics
    • G01N2021/6478—Special lenses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/062—LED's
    • G01N2201/0627—Use of several LED's for spectral resolution

Landscapes

  • Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • General Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
CN201280021684.2A 2011-05-04 2012-05-03 用于样本照明的方法、系统和装置 Active CN103608661B (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201161482307P 2011-05-04 2011-05-04
US61/482307 2011-05-04
US61/482,307 2011-05-04
PCT/US2012/036246 WO2012151358A2 (en) 2011-05-04 2012-05-03 Methods, systems, and apparatus for sample illumination

Publications (2)

Publication Number Publication Date
CN103608661A CN103608661A (zh) 2014-02-26
CN103608661B true CN103608661B (zh) 2017-07-11

Family

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Family Applications (1)

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CN201280021684.2A Active CN103608661B (zh) 2011-05-04 2012-05-03 用于样本照明的方法、系统和装置

Country Status (6)

Country Link
US (1) US9395240B2 (enExample)
EP (1) EP2681534B1 (enExample)
JP (1) JP6069303B2 (enExample)
CN (1) CN103608661B (enExample)
ES (1) ES2895959T3 (enExample)
WO (1) WO2012151358A2 (enExample)

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EP2605001A1 (en) * 2011-12-15 2013-06-19 Hain Lifescience GmbH A device and method for optically measuring fluorescence of nucleic acids in test samples and use of the device and method
CN103197056B (zh) * 2013-03-26 2014-12-31 山东博科生物产业有限公司 一种酶标仪
JP6261945B2 (ja) * 2013-10-29 2018-01-17 東芝メディカルシステムズ株式会社 自動分析装置
US20180003635A1 (en) * 2015-01-20 2018-01-04 Hyris Limited Detector for measuring fluorescence in a liquid sample
EP3141887A1 (de) 2015-09-09 2017-03-15 Siemens Healthcare Diagnostics Products GmbH Verfahren zum betreiben eines photometers
US10724945B2 (en) 2016-04-19 2020-07-28 Cascade Technologies Holdings Limited Laser detection system and method
US10180393B2 (en) 2016-04-20 2019-01-15 Cascade Technologies Holdings Limited Sample cell
EP3257584A1 (de) 2016-06-14 2017-12-20 Siemens Healthcare Diagnostics Products GmbH Verfahren zur positionierung von fluidvolumina in leitungen
GB201700905D0 (en) 2017-01-19 2017-03-08 Cascade Tech Holdings Ltd Close-Coupled Analyser
JP6856559B2 (ja) * 2018-01-23 2021-04-07 浜松ホトニクス株式会社 光測定装置及び光測定方法
JP7360008B2 (ja) * 2019-03-22 2023-10-12 日亜化学工業株式会社 精子の運動能力を増加させる方法及び装置
CN110542686A (zh) * 2019-09-30 2019-12-06 广东牧玛生命科技有限公司 一种多功能分析仪器
JP7462039B2 (ja) * 2019-10-31 2024-04-04 シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレイテッド 試料容器を特性評価するための前景照明の較正を提供する方法および装置
JP7465963B2 (ja) 2019-10-31 2024-04-11 シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレイテッド 試料および／または試料容器の特性評価のための背景照明の較正を提供する方法および装置
US20210208134A1 (en) * 2020-01-03 2021-07-08 Louay Khaled Fakhro Systems and methods of optically determining analyte concentrations

Citations (3)

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JP2000258341A (ja) * 1999-03-08 2000-09-22 Aloka Co Ltd 吸光度測定装置
FR2928220A1 (fr) * 2008-03-03 2009-09-04 F A R E Soc Par Actions Simpli Detecteur de fumee compact
CN101776599A (zh) * 2003-08-14 2010-07-14 塞通诺米/St有限责任公司 用于粒子分类系统的光学检测器

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AU2003243281A1 (en) * 2002-05-17 2003-12-02 Applera Corporation Optical instrument includung excitation source
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JP2000258341A (ja) * 1999-03-08 2000-09-22 Aloka Co Ltd 吸光度測定装置
CN101776599A (zh) * 2003-08-14 2010-07-14 塞通诺米/St有限责任公司 用于粒子分类系统的光学检测器
FR2928220A1 (fr) * 2008-03-03 2009-09-04 F A R E Soc Par Actions Simpli Detecteur de fumee compact

Also Published As

Publication number Publication date
JP6069303B2 (ja) 2017-02-01
WO2012151358A3 (en) 2013-12-12
US20140203173A1 (en) 2014-07-24
WO2012151358A2 (en) 2012-11-08
EP2681534A4 (en) 2015-01-07
EP2681534B1 (en) 2021-08-11
US9395240B2 (en) 2016-07-19
ES2895959T3 (es) 2022-02-23
JP2014517275A (ja) 2014-07-17
EP2681534A2 (en) 2014-01-08
CN103608661A (zh) 2014-02-26

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