CN103602706B - Muc1和gm-csf双基因共表达重组载体及其制备方法和应用 - Google Patents
Muc1和gm-csf双基因共表达重组载体及其制备方法和应用 Download PDFInfo
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- CN103602706B CN103602706B CN201310611552.1A CN201310611552A CN103602706B CN 103602706 B CN103602706 B CN 103602706B CN 201310611552 A CN201310611552 A CN 201310611552A CN 103602706 B CN103602706 B CN 103602706B
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CN201310611552.1A CN103602706B (zh) | 2013-11-25 | 2013-11-25 | Muc1和gm-csf双基因共表达重组载体及其制备方法和应用 |
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CN103602706B true CN103602706B (zh) | 2015-07-15 |
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CN106811476B (zh) * | 2015-11-27 | 2019-09-27 | 清华大学 | 一种用于多元蛋白复合物表达的成套载体及其应用 |
Citations (5)
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WO2002026819A2 (en) * | 2000-09-26 | 2002-04-04 | Roger Williams Hospital | Recombinant bcg vaccines for the prevention and treatment of cancer |
EP1256354A1 (en) * | 2001-05-11 | 2002-11-13 | Schering Corporation | Methods for treating cancer |
CN1513556A (zh) * | 2003-02-19 | 2004-07-21 | 台桂香 | 重组人muc1-mbp融合蛋白抗肿瘤疫苗及生产工艺 |
WO2004092348A2 (en) * | 2003-04-15 | 2004-10-28 | Novartis Ag | Method for production of oncolytic adenoviruses |
CN101575607A (zh) * | 2009-04-28 | 2009-11-11 | 中国人民解放军第四军医大学 | 一种基于人muc1重复序列与gm-csf融合表达的重组卡介苗疫苗 |
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Patent Citations (5)
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WO2002026819A2 (en) * | 2000-09-26 | 2002-04-04 | Roger Williams Hospital | Recombinant bcg vaccines for the prevention and treatment of cancer |
EP1256354A1 (en) * | 2001-05-11 | 2002-11-13 | Schering Corporation | Methods for treating cancer |
CN1513556A (zh) * | 2003-02-19 | 2004-07-21 | 台桂香 | 重组人muc1-mbp融合蛋白抗肿瘤疫苗及生产工艺 |
WO2004092348A2 (en) * | 2003-04-15 | 2004-10-28 | Novartis Ag | Method for production of oncolytic adenoviruses |
CN101575607A (zh) * | 2009-04-28 | 2009-11-11 | 中国人民解放军第四军医大学 | 一种基于人muc1重复序列与gm-csf融合表达的重组卡介苗疫苗 |
Non-Patent Citations (7)
Title |
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Inhibitory effects of recombinant bacillus Calmette-Guérin vaccines coexpressing tandem repeats of MUC1 and GM-CSF on the growth of breast cancer;Yuan Shifang(;《China Medical Abstracts(Surgery)》;20120331;第21卷(第1期);6-7 * |
MUC1P/Y基因体外冲击树突状细胞诱导抗瘤免疫反应;尹志伟 等;《中国免疫学杂志》;20040731;第20卷(第7期);第461页摘要 * |
NM_000758;Javadi,M. 等;《GENBANK》;20130915;第5页 * |
NM_001018016;Goudarzi,H.等;《GENBANK》;20131103;第5页 * |
pIRES2-EGFP-mGM质粒的构建及其在GM-CSF基因修饰性肿瘤疫苗中的应用;马明全 等;《天津医科大学学报》;20070331;第13卷(第1期);65-68 * |
人MUC1与GM-CSF基因融合真核表达质粒的构建与表达;袁时芳 等;《细胞与分子免疫学杂志》;20070131;第23卷(第1期);第18页摘要,第23页右栏第1-2段,第23页右栏第2段 * |
人骨形态发生蛋白2和人成纤维细胞生长因子2双基因共表达腺病毒载体的构建及鉴定;郭伟韬 等;《中国组织工程研究与临床康复》;20100611;第14卷(第24期);第4402页摘要 * |
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Inventor after: Wei Dan Inventor after: Li Kui Inventor after: Cao Yulin Inventor after: Zuo Baile Inventor after: Li Bingnan Inventor after: Lian Jie Inventor after: Lin Juntang Inventor after: Feng Huigen Inventor before: Cao Yulin Inventor before: Zuo Baile Inventor before: Li Bingnan Inventor before: Lian Jie Inventor before: Lin Juntang Inventor before: Feng Huigen |
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