CN103598586A - Anti-oxidation health-care food and preparation method thereof - Google Patents
Anti-oxidation health-care food and preparation method thereof Download PDFInfo
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- CN103598586A CN103598586A CN201310584032.6A CN201310584032A CN103598586A CN 103598586 A CN103598586 A CN 103598586A CN 201310584032 A CN201310584032 A CN 201310584032A CN 103598586 A CN103598586 A CN 103598586A
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- preparation
- vitamin
- lycopene
- seed extract
- grape seed
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- 238000002360 preparation method Methods 0.000 title claims abstract description 8
- 230000003064 anti-oxidating effect Effects 0.000 title abstract description 6
- 235000013305 food Nutrition 0.000 title abstract description 6
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims abstract description 24
- 229930003427 Vitamin E Natural products 0.000 claims abstract description 12
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims abstract description 12
- 235000019165 vitamin E Nutrition 0.000 claims abstract description 12
- 229940046009 vitamin E Drugs 0.000 claims abstract description 12
- 239000011709 vitamin E Substances 0.000 claims abstract description 12
- UPYKUZBSLRQECL-UKMVMLAPSA-N Lycopene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1C(=C)CCCC1(C)C)C=CC=C(/C)C=CC2C(=C)CCCC2(C)C UPYKUZBSLRQECL-UKMVMLAPSA-N 0.000 claims abstract description 11
- JEVVKJMRZMXFBT-XWDZUXABSA-N Lycophyll Natural products OC/C(=C/CC/C(=C\C=C\C(=C/C=C/C(=C\C=C\C=C(/C=C/C=C(\C=C\C=C(/CC/C=C(/CO)\C)\C)/C)\C)/C)\C)/C)/C JEVVKJMRZMXFBT-XWDZUXABSA-N 0.000 claims abstract description 11
- 235000002532 grape seed extract Nutrition 0.000 claims abstract description 11
- 229940087603 grape seed extract Drugs 0.000 claims abstract description 11
- OAIJSZIZWZSQBC-GYZMGTAESA-N lycopene Chemical compound CC(C)=CCC\C(C)=C\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C=C(/C)CCC=C(C)C OAIJSZIZWZSQBC-GYZMGTAESA-N 0.000 claims abstract description 11
- 235000012661 lycopene Nutrition 0.000 claims abstract description 11
- 229960004999 lycopene Drugs 0.000 claims abstract description 11
- 239000001751 lycopene Substances 0.000 claims abstract description 11
- ZCIHMQAPACOQHT-ZGMPDRQDSA-N trans-isorenieratene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/c1c(C)ccc(C)c1C)C=CC=C(/C)C=Cc2c(C)ccc(C)c2C ZCIHMQAPACOQHT-ZGMPDRQDSA-N 0.000 claims abstract description 11
- 239000001717 vitis vinifera seed extract Substances 0.000 claims abstract description 11
- 239000002994 raw material Substances 0.000 claims abstract description 4
- 230000003179 granulation Effects 0.000 claims abstract description 3
- 238000005469 granulation Methods 0.000 claims abstract description 3
- 239000003963 antioxidant agent Substances 0.000 claims description 9
- 230000003078 antioxidant effect Effects 0.000 claims description 9
- 235000006708 antioxidants Nutrition 0.000 claims description 9
- 235000013376 functional food Nutrition 0.000 claims description 7
- 239000002245 particle Substances 0.000 claims description 7
- 239000000463 material Substances 0.000 claims description 6
- 239000007901 soft capsule Substances 0.000 claims description 5
- 239000000203 mixture Substances 0.000 claims description 4
- 239000002775 capsule Substances 0.000 claims description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 2
- 239000008188 pellet Substances 0.000 claims description 2
- 239000003826 tablet Substances 0.000 claims description 2
- 235000020985 whole grains Nutrition 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 6
- 230000003647 oxidation Effects 0.000 abstract description 4
- 238000007254 oxidation reaction Methods 0.000 abstract description 4
- 230000001681 protective effect Effects 0.000 abstract description 2
- 238000001035 drying Methods 0.000 abstract 1
- 150000003254 radicals Chemical class 0.000 description 6
- 239000008187 granular material Substances 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 230000005778 DNA damage Effects 0.000 description 2
- 231100000277 DNA damage Toxicity 0.000 description 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- 206010028980 Neoplasm Diseases 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 201000011510 cancer Diseases 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 244000241235 Citrullus lanatus Species 0.000 description 1
- 235000012828 Citrullus lanatus var citroides Nutrition 0.000 description 1
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 description 1
- 229940123457 Free radical scavenger Drugs 0.000 description 1
- 108010010803 Gelatin Proteins 0.000 description 1
- 206010058467 Lung neoplasm malignant Diseases 0.000 description 1
- 235000007688 Lycopersicon esculentum Nutrition 0.000 description 1
- 240000003768 Solanum lycopersicum Species 0.000 description 1
- 208000005718 Stomach Neoplasms Diseases 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000003026 anti-oxygenic effect Effects 0.000 description 1
- 230000003143 atherosclerotic effect Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 235000021466 carotenoid Nutrition 0.000 description 1
- 150000001747 carotenoids Chemical class 0.000 description 1
- 230000024245 cell differentiation Effects 0.000 description 1
- 230000010261 cell growth Effects 0.000 description 1
- 231100000433 cytotoxic Toxicity 0.000 description 1
- 230000001472 cytotoxic effect Effects 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000000378 dietary effect Effects 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 230000002526 effect on cardiovascular system Effects 0.000 description 1
- 206010017758 gastric cancer Diseases 0.000 description 1
- 210000001156 gastric mucosa Anatomy 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 239000008273 gelatin Substances 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 235000011852 gelatine desserts Nutrition 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 235000013402 health food Nutrition 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 230000003859 lipid peroxidation Effects 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 201000005202 lung cancer Diseases 0.000 description 1
- 208000020816 lung neoplasm Diseases 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- XKLJHFLUAHKGGU-UHFFFAOYSA-N nitrous amide Chemical compound ON=N XKLJHFLUAHKGGU-UHFFFAOYSA-N 0.000 description 1
- 239000005022 packaging material Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 239000002516 radical scavenger Substances 0.000 description 1
- 201000011549 stomach cancer Diseases 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Mycology (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Botany (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to an anti-oxidation health-care food and a preparation method thereof. The food is mainly prepared from the following raw materials in parts by weight: 0.01-1 part of lycopene, 0.1-2 parts of grape seed extract and 0.01-1 part of vitamin E through mixed granulation and drying, and has the effects of removing radicals in bodies and resisting oxidation, wherein vitamin E has a protective effect on the anti-oxidation effect of the grape seed extract and the lycopene, so that the anti-oxidation effect of the food can be further improved.
Description
Technical field
The present invention relates to a kind of health food, particularly relate to a kind of for oxidation-resisting health-care food and preparation method thereof.
Background technology
In the environment of modern high pollution, everyone must be in the face of the threat of free radical.Add that operating pressure is large, dietary structure is unbalanced, human body natural's oxidation resistance is damaged, and resistivity reduces, and free radical quantity constantly increases.In order to resist the infringement of radical pair health, nutritionist suggestion is antioxidant by food to adding free radical scavenger in body.
In body, all prove with experiment in vitro, the main active OPC of grape seed extract can be removed free radical, suppress lipid peroxidation and DNA damage that free radical too much causes, human mammary, lung and stomach cancer cell are had to cytotoxic effect, promote normal gastric mucosa Growth of Cells and survival.Lycopene is a kind of natural carotenoid being extensively present in the vegetables such as tomato, watermelon and fruit.In recent years research is found, its by the removing of the cancellation of singlet oxygen, free radical, blocking nitrosamine formation formation, Cell differentiation inducing activity, increase immunity, reduce DNA damage and the multiple modes of action such as impact on GJIC, the effect such as play cancer-resisting, angiocardiopathy preventing and delay senility.The diseases such as that vitamin E can effectively prevent is cardiovascular, atherosclerotic, cancer, its disease-resistant mechanism is relevant with its antioxygenic property.
Summary of the invention
The object of this invention is to provide a kind of antioxidant functional food and preparation method thereof, to remove interior free yl, play oxidation resistant effect.
Antioxidant functional food of the present invention is that the raw material with following portions by weight is prepared from:
0.1～2 part of 0.01～1 part of grape seed extract of lycopene
0.01～1 part of vitamin E.
The preparation method of antioxidant functional food of the present invention comprises the following steps:
1) lycopene of described parts by weight, grape seed extract, vitamin E are crossed to 60 mesh sieves, mix;
2) add auxiliary material, mix, with 70～99wt% alcohol granulation, dry, control pellet moisture < 3～5wt%, whole grain, obtains particle.
The present invention can, according to common process, further make above-mentioned particle the various regular dosage forms such as capsule, soft capsule, tablet.
Product of the present invention has the interior free yl of removing, oxidation resistant effect.Primary raw material grape seed extract, lycopene and the vitamin E using in the present invention has all been proved to be antioxidant safely and effectively; the present invention finds; three is combined; wherein vitamin E can also play a protective role to the antioxidation of other two kinds of materials, can further improve the antioxidation of product.
The specific embodiment
Embodiment 1
Get 0.015 part of lycopene, 0.2 part of grape seed extract, 0.05 part of vitamin E, crosses 60 mesh sieves, mixes, and adds appropriate amount of auxiliary materials, with 85% ethanolic solution, granulates, and particle is dried to moisture and is less than 5% at 60 ℃, and whole, direct tablet compressing is made tablet.
Embodiment 2
Get 0.02 part of lycopene, 0.3 part of grape seed extract, 0.08 part of vitamin E, crosses 60 mesh sieves, mixes, and adds appropriate amount of auxiliary materials, with 90% ethanolic solution, granulates, and particle is dried to moisture and is less than 5% at 60 ℃, whole, in incapsulating, makes capsule.
Embodiment 3
Get 0.05 part of lycopene, 0.5 part of grape seed extract, 0.08 part of vitamin E, crosses 60 mesh sieves, mixes, and adds appropriate amount of auxiliary materials, with 90% ethanolic solution, granulates, and particle is dried to moisture and is less than 5%, whole at 60 ℃.Using gelatin, glycerine as soft capsule packaging material, on soft capsule forming machine, prepare soft capsule.
Claims (3)
1. an antioxidant functional food is that the raw material with following portions by weight is prepared from:
0.1～2 part of 0.01～1 part of grape seed extract of lycopene
0.01～1 part of vitamin E.
2. the preparation method of claim 1 antioxidant functional food, comprises the following steps:
1) lycopene of described parts by weight, grape seed extract, vitamin E are crossed to 60 mesh sieves, mix;
2) add auxiliary material, mix, with 70～99wt% alcohol granulation, dry, control pellet moisture < 3～5wt%, whole grain, obtains particle.
3. the preparation method of antioxidant functional food according to claim 2, is characterized in that described particle to make capsule, soft capsule or tablet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310584032.6A CN103598586A (en) | 2013-11-20 | 2013-11-20 | Anti-oxidation health-care food and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310584032.6A CN103598586A (en) | 2013-11-20 | 2013-11-20 | Anti-oxidation health-care food and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103598586A true CN103598586A (en) | 2014-02-26 |
Family
ID=50116900
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310584032.6A Pending CN103598586A (en) | 2013-11-20 | 2013-11-20 | Anti-oxidation health-care food and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103598586A (en) |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104824047A (en) * | 2015-04-03 | 2015-08-12 | 王屹萍 | Natural oxidation and radiation resistant sterilization material and preparation method thereof |
| CN105795242A (en) * | 2014-12-29 | 2016-07-27 | 伊启棒（天津）科技发展有限公司 | Liver-protection food |
| CN105795243A (en) * | 2014-12-29 | 2016-07-27 | 伊启棒（天津）科技发展有限公司 | Liver-protection food preparation method |
| CN105876435A (en) * | 2014-10-22 | 2016-08-24 | 会同县贤胜油业有限责任公司 | Anti-oxidizing composition soft capsule and preparation method thereof |
| CN106262897A (en) * | 2016-08-17 | 2017-01-04 | 佛山市夕泪饮料有限公司 | A kind of beverage |
| CN107125757A (en) * | 2017-04-10 | 2017-09-05 | 浙江新维士生物科技有限公司 | Functional food composite and oral products and preparation method thereof and their application |
| CN108618137A (en) * | 2018-07-18 | 2018-10-09 | 深圳极醇健康产业股份有限公司 | A kind of lycopene capsules and preparation method thereof |
| CN108887678A (en) * | 2018-07-18 | 2018-11-27 | 深圳极醇健康产业股份有限公司 | A kind of tomato red plain piece and preparation method thereof |
| CN112674336A (en) * | 2020-12-21 | 2021-04-20 | 石家庄以岭药业股份有限公司 | Antioxidant composition and antioxidant health food |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1618333A (en) * | 2004-12-09 | 2005-05-25 | 桂林莱茵生物制品有限公司 | Anti-oxidation health-care food, and its prodn. method |
| CN102511821A (en) * | 2011-12-30 | 2012-06-27 | 新疆医科大学 | Composite lipid-lowering soft capsule preparation prepared by lycopene and grapestone extracts and preparation method of composite lipid-lowering soft capsule preparation |
| CN103007252A (en) * | 2012-12-14 | 2013-04-03 | 广东长兴科技保健品有限公司 | Antioxidation health care product and preparation method thereof |
| CN103120798A (en) * | 2013-01-10 | 2013-05-29 | 施冬云 | Preparation method and application of phospholipid complex with anti-oxidative stress |
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-
2013
- 2013-11-20 CN CN201310584032.6A patent/CN103598586A/en active Pending
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| CN1618333A (en) * | 2004-12-09 | 2005-05-25 | 桂林莱茵生物制品有限公司 | Anti-oxidation health-care food, and its prodn. method |
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| CN103120798A (en) * | 2013-01-10 | 2013-05-29 | 施冬云 | Preparation method and application of phospholipid complex with anti-oxidative stress |
| CN103230015A (en) * | 2013-05-20 | 2013-08-07 | 李铁清 | Extract compound for delaying senility, improving immunity and preventing and resisting cancer |
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| Title |
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| 张俊刚: "葡萄籽提取物复合物对小鼠的抗氧化作用", 《医学动物防制》, vol. 27, no. 7, 31 July 2011 (2011-07-31), pages 609 - 610 * |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105876435A (en) * | 2014-10-22 | 2016-08-24 | 会同县贤胜油业有限责任公司 | Anti-oxidizing composition soft capsule and preparation method thereof |
| CN105795242A (en) * | 2014-12-29 | 2016-07-27 | 伊启棒（天津）科技发展有限公司 | Liver-protection food |
| CN105795243A (en) * | 2014-12-29 | 2016-07-27 | 伊启棒（天津）科技发展有限公司 | Liver-protection food preparation method |
| CN104824047A (en) * | 2015-04-03 | 2015-08-12 | 王屹萍 | Natural oxidation and radiation resistant sterilization material and preparation method thereof |
| CN106262897A (en) * | 2016-08-17 | 2017-01-04 | 佛山市夕泪饮料有限公司 | A kind of beverage |
| CN107125757A (en) * | 2017-04-10 | 2017-09-05 | 浙江新维士生物科技有限公司 | Functional food composite and oral products and preparation method thereof and their application |
| CN108618137A (en) * | 2018-07-18 | 2018-10-09 | 深圳极醇健康产业股份有限公司 | A kind of lycopene capsules and preparation method thereof |
| CN108887678A (en) * | 2018-07-18 | 2018-11-27 | 深圳极醇健康产业股份有限公司 | A kind of tomato red plain piece and preparation method thereof |
| CN112674336A (en) * | 2020-12-21 | 2021-04-20 | 石家庄以岭药业股份有限公司 | Antioxidant composition and antioxidant health food |
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Application publication date: 20140226 |