CN103596960B - 6,7-二氢咪唑并[2,1-b][1,3]噁嗪杀菌剂 - Google Patents

6,7-二氢咪唑并[2,1-b][1,3]噁嗪杀菌剂 Download PDF

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Publication number
CN103596960B
CN103596960B CN201280029213.6A CN201280029213A CN103596960B CN 103596960 B CN103596960 B CN 103596960B CN 201280029213 A CN201280029213 A CN 201280029213A CN 103596960 B CN103596960 B CN 103596960B
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China
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reference example
group
piperazine
compound
diyl
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Expired - Fee Related
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CN201280029213.6A
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Chinese (zh)
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CN103596960A (zh
Inventor
川野芳和
原口佳和
佐佐木博文
植松幸崇
壶内英继
矢田裕美
清水洋
小桥穗
小桥一穗
系谷元宏
田井国宪
竹村勋
林美佳世
桥诘博之
松叶未贵
中村出
陈修浩
松本真
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Otsuka Pharmaceutical Co Ltd
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Otsuka Pharmaceutical Co Ltd
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CN201280029213.6A 2011-04-15 2012-04-13 6,7-二氢咪唑并[2,1-b][1,3]噁嗪杀菌剂 Expired - Fee Related CN103596960B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161476003P 2011-04-15 2011-04-15
US61/476,003 2011-04-15
PCT/JP2012/060645 WO2012141338A1 (en) 2011-04-15 2012-04-13 6,7 - dihydroimidazo [2, 1 - b] [1, 3] oxazine bactericides

Publications (2)

Publication Number Publication Date
CN103596960A CN103596960A (zh) 2014-02-19
CN103596960B true CN103596960B (zh) 2016-11-16

Family

ID=46168570

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201280029213.6A Expired - Fee Related CN103596960B (zh) 2011-04-15 2012-04-13 6,7-二氢咪唑并[2,1-b][1,3]噁嗪杀菌剂

Country Status (5)

Country Link
US (1) US9051333B2 (https=)
EP (1) EP2697232B1 (https=)
JP (1) JP5916739B2 (https=)
CN (1) CN103596960B (https=)
WO (1) WO2012141338A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI687409B (zh) 2014-08-28 2020-03-11 日商大塚製藥股份有限公司 稠合雜環化合物
CN105753817A (zh) * 2015-01-01 2016-07-13 成都贝斯凯瑞生物科技有限公司 一类取代氮杂环衍生物及其应用
CN107207532B (zh) * 2015-01-29 2019-07-30 南京明德新药研发股份有限公司 抗肺结核病的硝基咪唑衍生物
JP6905506B2 (ja) * 2016-02-26 2021-07-21 大塚製薬株式会社 ピペリジン誘導体
RU2657168C2 (ru) * 2016-04-29 2018-06-08 Общество с ограниченной ответственностью "Общество Сферического Кино" Программно-аппаратный комплекс для автоматической калибровки многопроекторных систем с возможностью воспроизводить контент в высоком разрешении с использованием средств шифрования и цифровой дистрибьюции, способ шифрования контента для использования в способе воспроизведения контента
WO2019128963A1 (zh) * 2017-12-26 2019-07-04 南京明德新药研发股份有限公司 抗肺结核病的硝基咪唑衍生物
WO2020144686A1 (en) * 2019-01-08 2020-07-16 B. G. Negev Technologies And Applications Ltd., At Ben-Gurion University Antimicrobial compounds and compositions comprising same
WO2020179859A1 (ja) 2019-03-06 2020-09-10 第一三共株式会社 ピロロピラゾール誘導体
CN110452188A (zh) * 2019-09-12 2019-11-15 蚌埠学院 一种伏硫西汀的制备方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101965353A (zh) * 2008-03-26 2011-02-02 全球结核病药物研发联盟 共价连接到取代苯基噁唑烷酮的双环硝基咪唑类
WO2011014776A1 (en) * 2009-07-31 2011-02-03 Global Alliance For Tb Drug Development Nitroimidazooxazine and nitroimidazooxazole analogues and their uses
WO2011014774A1 (en) * 2009-07-31 2011-02-03 Global Alliance For Tb Drug Development Nitroimidazooxazines and their uses in anti-tubercular therapy

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07330B2 (ja) 1991-07-06 1995-01-11 日精樹脂工業株式会社 駆動装置
US5668127A (en) 1995-06-26 1997-09-16 Pathogenesis Corporation Nitroimidazole antibacterial compounds and methods of use thereof
TWI347946B (en) 2002-10-11 2011-09-01 Otsuka Pharma Co Ltd 2,3-dihydro-6-nitroimidazo[2,1-b]oxazole compound
WO2005042542A1 (en) 2003-10-31 2005-05-12 Otsuka Pharmaceutical Co., Ltd. 2,3-dihydro-6-nitroimidazo (2,1-b) oxazole compounds for the treatment of tuberculosis
JP4761756B2 (ja) 2003-10-31 2011-08-31 大塚製薬株式会社 ２，３−ジヒドロイミダゾ［２，１−ｂ］オキサゾ−ル化合物

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101965353A (zh) * 2008-03-26 2011-02-02 全球结核病药物研发联盟 共价连接到取代苯基噁唑烷酮的双环硝基咪唑类
WO2011014776A1 (en) * 2009-07-31 2011-02-03 Global Alliance For Tb Drug Development Nitroimidazooxazine and nitroimidazooxazole analogues and their uses
WO2011014774A1 (en) * 2009-07-31 2011-02-03 Global Alliance For Tb Drug Development Nitroimidazooxazines and their uses in anti-tubercular therapy

Also Published As

Publication number Publication date
WO2012141338A1 (en) 2012-10-18
EP2697232A1 (en) 2014-02-19
CN103596960A (zh) 2014-02-19
US20140031342A1 (en) 2014-01-30
EP2697232B1 (en) 2016-05-18
JP5916739B2 (ja) 2016-05-11
JP2014510695A (ja) 2014-05-01
US9051333B2 (en) 2015-06-09

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