CN103585542B - Chinese medicinal pill for treating globus hysteriocus - Google Patents

Chinese medicinal pill for treating globus hysteriocus Download PDF

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CN103585542B
CN103585542B CN201310488668.0A CN201310488668A CN103585542B CN 103585542 B CN103585542 B CN 103585542B CN 201310488668 A CN201310488668 A CN 201310488668A CN 103585542 B CN103585542 B CN 103585542B
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fructus
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CN103585542A (en
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程广金
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Abstract

The invention discloses a Chinese medicinal pill for treating globus hysteriocus, and relates to the technical field of traditional Chinese medicines. The Chinese medicinal pill for treating globus hysteriocus is a medicament which is prepared from the following raw medicinal materials: 140-160 g of rhizoma cyperi, 140-160 g of tangerine peel, 30-50 g of processed rhizoma pinelliae, 140-160 g of bitter orange, 110-130 g of magnolia officinalis rehdm 140-160 g of costus root, 80-100 g of cardamom, 110-130 g of perillaseed, 140-160 g of Chinese magnoliavine fruit, 140-160 g of green tangerine peel and 290-310 g of massa medicata fermentata fujianensis. The selected and used Chinese herbal medicines conform to the regulations of Chinese pharmacopoeia; according to the combination, the Chinese medicinal pill has the effects of promoting qi circulation, relieving depression, drying dampness and resolving phlegm, has an excellent treatment effect only on the globus hysteriocus, can be used for preventing the diseases from occurring, and has the characteristics of quick response, short treatment period, high cure rate and no toxic or side effect.

Description

A kind of Chinese medicine pill being used for the treatment of globus hystericus
Technical field
The present invention relates to field of Chinese herbal medicine technology, be specifically related to a kind of Chinese medicine pill being used for the treatment of globus hystericus.
Background technology
Globus hystericus is because long-term anxiety and rage, psychentonia or bend over the desk for a long time thinks hard the impairment of the spleen or stagnation of liver-QI and spleen, dysfunction of the spleen in transportation, retention of water-damp in the body, coagulates for expectorant is turbid, and stagnation of QI phlegm stagnancy is on chest and diaphragm.Clinical manifestation is close in the heart, blocks in pharynx if any foreign body, tell do not go out, pharynx not under, accompany dry pharynx, scorching hot, itching throat, pharyngalgia etc., a kind of symptom of tongue greasy, stringy and rolling pulse in vain more.Be similar to the class diseases such as the neurosis of modern medicine, pharyngitis.In being more common in, young women, the onset because of depressed emotion, its state of an illness and Nervous and Mental Factors have close ties.The main pathogenesis of primary disease is dysfunction of the spleen in transportation, stagnation of QI phlegm stagnancy.By dialectical in clinical, take promoting QI circulation for relieving depression, drying dampness to eliminate phlegm is method for the treatment of, have received good therapeutic effect.
Summary of the invention
It is high that technical problem to be solved by this invention is to provide a kind of cure rate, the safe and reliable Chinese medicine pill being used for the treatment of globus hystericus.
Technical problem to be solved by this invention realizes by the following technical solutions:
Be used for the treatment of a Chinese medicine pill for globus hystericus, be made up of the crude drug of following weight,
Rhizoma Cyperi 140-160 gram, Pericarpium Citri Reticulatae 140-160 gram, Rhizoma Pinelliae Preparata 30-50 gram, Fructus Aurantii 140-160 gram, CORTEX MAGNOLIAE OFFICINALIS from Sichuan of China 110-130 gram, Radix Aucklandiae 140-160 gram, Fructus Amomi 80-100 gram, Fructus Perillae 110-130 gram, Fructus Schisandrae Chinensis 140-160 gram, Pericarpium Citri Reticulatae Viride 140-160 gram, Massa Medicata Fermentata 290-310 gram.
The preferred weight of each crude drug is:
Rhizoma Cyperi 150 grams, Pericarpium Citri Reticulatae 150 grams, Rhizoma Pinelliae Preparata 40 grams, Fructus Aurantii 150 grams, CORTEX MAGNOLIAE OFFICINALIS from Sichuan of China 120 grams, the Radix Aucklandiae 150 grams, Fructus Amomi 90 grams, Fructus Perillae 120 grams, Fructus Schisandrae Chinensis 150 grams, 150 grams, Pericarpium Citri Reticulatae Viride, Massa Medicata Fermentata 300 grams.
Crude drug used by the present invention can be bought from common Chinese shop and obtain, and its specification meets national Chinese crude drug standard.
Another object of the present invention is to provide a kind of method preparing the present composition, comprises the steps,
1) each crude drug is taken by following weight: Rhizoma Cyperi 150 grams, Pericarpium Citri Reticulatae 150 grams, Rhizoma Pinelliae Preparata 40 grams, Fructus Aurantii 150 grams, CORTEX MAGNOLIAE OFFICINALIS from Sichuan of China 120 grams, the Radix Aucklandiae 150 grams, Fructus Amomi 90 grams, Fructus Perillae 120 grams, Fructus Schisandrae Chinensis 150 grams, 150 grams, Pericarpium Citri Reticulatae Viride, Massa Medicata Fermentata 300 grams;
2) by above-mentioned each taste crude drug pulverization, with Mel, group becomes ball, every ball 0.4-0.6 gram, as Semen phaseoli radiati size, and high-temperature sterilization.
1, pharmacology analysis:
Rhizoma Cyperi: treating the liver discomfort in the stomach, depression of QI, breast abdomen distending pain over the hypochondrium, phlegm retention feeling of fullness, menoxenia, bleeding not during menses.
Pericarpium Citri Reticulatae: cure mainly distension and fullness of the chest and abdomen, anorexia, vomiting hiccup, cough with copious phlegm.Also fish, Eriocheir sinensis poison is separated.
Rhizoma Pinelliae Preparata: drying dampness to eliminate phlegm.For abundant expectoration cough with asthma, phlegm retention vertigo and palpitation, dizziness due to wind-phlegm, syncope due to accumulation of phlegm is had a headache.
Fructus Aurantii: control chest and diaphragm expectorant stagnant, the feeling of stuffiness in chest, coerces swollen, food stagnation, eructation, vomiting, heavy after dysentery, proctoptosis, uterine prolapse.
CORTEX MAGNOLIAE OFFICINALIS from Sichuan of China: cure mainly dampness expectorant, the therapeutic method to keep the adverse QI flowing downwards is except full.For humidity hysteresis damaging the spleen and stomach, gastral cavity painful abdominal mass is vomited and diarrhoea, and stagnation of QI due to dyspepsia, abdominal distention constipation, phlegm retention is breathed with cough.
The Radix Aucklandiae: cure mainly the invasion by pathogenic cold stagnation of QI, chest and abdomen swelling and pain, vomiting, has loose bowels, dysentery tenesmus, colic of cold type.
Fructus Amomi: cure mainly stomachache painful abdominal mass swollen, anorexia dyspepsia, dysphagic vomiting, diarrhea due to cold pathogen cold-dysentery, pregnant fetal movement.
Fructus Perillae: control cough with dyspnea, phlegm dyspnea, the stagnation of QI, constipation.
Fructus Schisandrae Chinensis: control the deficiency of the lung and breath with cough, xerostomia is done thirsty, spontaneous perspiration, night sweat, impairment caused by overstrain weakness and emaciation, emission, chronic diarrhea chronic dysentery.
Pericarpium Citri Reticulatae Viride: cure mainly breast side of body gastralgia, hernia, food stagnation, swelling of the breast, nodule in the breast, chronic malaria addiction block.
Massa Medicata Fermentata: cure mainly the feeling of stuffiness in chest of getting ill from overeating, abdomen boils vomiting and diarrhoea, dysentery, headache due to common cold, and children's hinders hungry mistake and satisfies.
2, usage and consumption:
Instruction: every day 20-30 gram, sooner or later sub-service 7 days is a course for the treatment of.
3, the present composition has carried out a large amount of clinical trials of a large amount of animal acute toxicity tests, long-term toxicity test for animals and disease therapy, drops into the use link of disease therapy provide science and objective foundation to this medicine.Its test method and result of the test are distinguished as follows:
1) animal acute toxicity test is carried out to pill prepared by the present invention:
Medicine: the crude drug used by the present invention is bought from common Chinese shop and obtained, and its specification meets national Chinese crude drug standard.
Experimental animal: white mice, body weight is at about 50g, and male and female Stochastic choice, is bought by market.
Method and result: get white mice 30, hungry 20 hours, feeding 50ml by filling with several times every every day, feeding one week continuously, observing 10 days, and mice is movable normal, non-toxic reaction, without dead.Show that oral liquid is without acute toxicity, clinical medicine dose safety.
2) long-term toxicity test for animals is carried out to pill prepared by the present invention:
Experimental animal: rat, body weight is at 120-130g, and male and female Stochastic choice, is bought by market.
Method and result: get rat 20, be divided into 2 groups, often organize 10, wherein the 1st group as administration group, 40-50ml is fed by filling with several times every every day, 2nd group of diet as a control group, once a day, continuous irrigation is fed 90 days, survey body weight, 24 hours sacrificed by decapitation after last administration, survey blood, routine urinalysis, liver function, renal function, core, the internal organs such as kidney, the change of tissues observed form, observe the effect of dosage, observe diet, movable change, experiment proves that administration group compares without significant change with matched group, equal non-toxic reaction, a kind of safe drugs.
4, diagnostic criteria
1) clinical diagnosis: close in the heart, blocks if any foreign body in pharynx, tell do not go out, pharynx not under, accompany dry pharynx, scorching hot, itching throat, pharyngalgia, tongue is the symptom such as greasy, stringy and rolling pulse in vain more.
2) in order to verify clinical efficacy, this prescription is tried out in Affiliated Hospital of Chinese medicine institute first of Anhui Province respectively, and random selecting is 50 routine globus hystericus patients wherein.
3) Therapeutic Method: take pill 20-30 gram of the present invention every day, sub-service sooner or later.
4) efficacy determination:
Recovery from illness: every symptom all disappears, and without sense of discomfort, does not affect orthobiosis and work;
Effective: every symptom disappears substantially, after treatment, symptom obviously alleviates, and does not affect daily life and work;
Effective: related symptoms and sign are improved, but unstable condition, there is recurrence after drug withdrawal;
Invalid: to treat rear symptom, sign compared with before treatment without any change;
Concrete therapeutic outcome is see table 1.
Table 1
Number of cases Recovery from illness Effective Effectively Invalid Effective percentage (%)
50 20 20 8 2 96
5, points for attention:
1. diet should be light, gives up alcohol and pungent, raw and cold, greasy food.
2. child, women breast-feeding their children, elderly and infirm should take under doctor instructs.
3. driver, work high above the ground person are cautious use of.
4. strictly take by usage and dosage, this medicine should not be taken for a long time in a large number.
5. pair this medicine and alcohol intolerance person forbidding, allergic constitution person be cautious use of.
6. prohibit the use when this property of drug changes.
7. please this medicine is placed on the place that child can not contact.
8. as used other medicines, please Ref Dr or pharmacist before using this medicine.
The invention has the beneficial effects as follows: the Chinese herbal medicine selected by the present invention all meets Pharmacopoeia of the People's Republic of China regulation, there is according to compatibility the present invention effect of promoting QI circulation for relieving depression, drying dampness to eliminate phlegm, only there is good therapeutical effect to globus hystericus, and the generation of primary disease can be prevented, instant effect, short treating period, cure rate be high, have no side effect.
Detailed description of the invention
The technological means realized to make the present invention, creation characteristic, reaching object and effect is easy to understand, below in conjunction with specific embodiment, setting forth the present invention further.
Embodiment 1
Take each crude drug: Radix Angelicae Sinensis 12 grams, Radix Paeoniae Alba 15 grams, Rhizoma Chuanxiong 12 grams, Radix Bupleuri 12 grams, Rhizoma Cyperi 12 grams, Herba Schizonepetae 12 grams, Radix Saposhnikoviae 12 grams, 6 grams, Radix Glycyrrhizae, Radix Scutellariae 15 grams, Fructus Viticis 12 grams, 3, Rhizoma Zingiberis Recens.
By above-mentioned each taste crude drug pulverization, with Mel, group becomes ball, every ball 0.4-0.6 gram, as Semen phaseoli radiati size, and high-temperature sterilization.
Embodiment 2
Each crude drug is taken: Radix Angelicae Sinensis 13 grams, Radix Paeoniae Alba 16 grams, Rhizoma Chuanxiong 13 grams, Radix Bupleuri 13 grams, Rhizoma Cyperi 13 grams, Herba Schizonepetae 13 grams, Radix Saposhnikoviae 13 grams, 7 grams, Radix Glycyrrhizae, Radix Scutellariae 16 grams, Fructus Viticis 13 grams, 4, Rhizoma Zingiberis Recens by following parts by weight.
By above-mentioned each taste crude drug pulverization, with Mel, group becomes ball, every ball 0.4-0.6 gram, as Semen phaseoli radiati size, and high-temperature sterilization.
Embodiment 3
Each crude drug is taken: Radix Angelicae Sinensis 11 grams, Radix Paeoniae Alba 14 grams, Rhizoma Chuanxiong 11 grams, Radix Bupleuri 11 grams, Rhizoma Cyperi 11 grams, Herba Schizonepetae 11 grams, Radix Saposhnikoviae 11 grams, 5 grams, Radix Glycyrrhizae, Radix Scutellariae 14 grams, Fructus Viticis 11 grams, 2, Rhizoma Zingiberis Recens by following parts by weight.
By above-mentioned each taste crude drug pulverization, with Mel, group becomes ball, every ball 0.4-0.6 gram, as Semen phaseoli radiati size, and high-temperature sterilization.
Model case:
Case 1
For so-and-so, female, 30 years old, company worker, people from Jieshou City, Anhui Province.Conscious pharyngeally have foreign body sensation, tell do not go out, pharynx not under, more than xerostomia, itching throat half a year; Every inspection is all without organic disease; Multi-treatment has not yet fully recovered, and in November, 2011 examines here, and after 2 courses for the treatment of of oral Drug therapy of the present invention, symptom all disappears.Follow up a case by regular visits to and do not recur for 1 year.
Case 2
Lee so-and-so, female, 25 years old, company personnel, Dai Qiao people from town, Jieshou City, Anhui Province.In June, 2010, because of pharyngeal discomfort, companion's breast side of body feeling of distension and oppression, examines as globus hystericus at local hospital; Oral drug therapy is heavy time light during the state of an illness; Conscious exacerbation of symptoms over nearly one month; In December, 2010 examines here, and after the course for the treatment of of oral administration Drug therapy of the present invention, symptom all disappears.Follow up a case by regular visits to and do not recur for 1 year.
Case 3
Time so-and-so, man, 35 years old, peasant, Dai Qiao people from town, Jieshou City, Anhui Province.Because domestic problem is gloomy for a long time, obviously feel in August, 2010 pharynx in as thing block, tell do not go out, pharynx not under, with dryness of the mouth and throat; Examine as globus hystericus in institute of traditional Chinese medicine of county, and treat more than ten skies, symptom is improved not yet.JIUYUE examines here, and after the course for the treatment of of oral Drug therapy of the present invention, symptom all disappears, and whole body is without any discomfort.Follow up a case by regular visits to and do not recur for 1 year.
More than show and describe ultimate principle of the present invention and principal character and advantage of the present invention.The technical staff of the industry should understand; the present invention is not restricted to the described embodiments; what describe in above-described embodiment and description just illustrates principle of the present invention; without departing from the spirit and scope of the present invention; the present invention also has various changes and modifications, and these changes and improvements all fall in the claimed scope of the invention.Application claims protection domain is defined by appending claims and equivalent thereof.

Claims (2)

1. one kind is used for the treatment of the Chinese medicine pill of globus hystericus, it is characterized in that, be made up of the crude drug of following weight: Rhizoma Cyperi 140-160 gram, Pericarpium Citri Reticulatae 140-160 gram, Rhizoma Pinelliae Preparata 30-50 gram, Fructus Aurantii 140-160 gram, CORTEX MAGNOLIAE OFFICINALIS from Sichuan of China 110-130 gram, Radix Aucklandiae 140-160 gram, Fructus Amomi 80-100 gram, Fructus Perillae 110-130 gram, Fructus Schisandrae Chinensis 140-160 gram, Pericarpium Citri Reticulatae Viride 140-160 gram, Massa Medicata Fermentata 290-310 gram; By above-mentioned each taste crude drug pulverization, with Mel, group becomes ball, every ball 0.4-0.6 gram, high-temperature sterilization.
2. a kind of Chinese medicine pill being used for the treatment of globus hystericus according to claim 1, it is characterized in that, be made up of the crude drug of following weight: Rhizoma Cyperi 150 grams, Pericarpium Citri Reticulatae 150 grams, Rhizoma Pinelliae Preparata 40 grams, Fructus Aurantii 150 grams, CORTEX MAGNOLIAE OFFICINALIS from Sichuan of China 120 grams, the Radix Aucklandiae 150 grams, Fructus Amomi 90 grams, Fructus Perillae 120 grams, Fructus Schisandrae Chinensis 150 grams, 150 grams, Pericarpium Citri Reticulatae Viride, Massa Medicata Fermentata 300 grams; By above-mentioned each taste crude drug pulverization, with Mel, group becomes ball, every ball 0.4-0.6 gram, high-temperature sterilization.
CN201310488668.0A 2013-10-18 2013-10-18 Chinese medicinal pill for treating globus hysteriocus Expired - Fee Related CN103585542B (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102716449A (en) * 2012-06-18 2012-10-10 天津开发区经经新优技术产品开发有限公司 Chinese patent drug and traditional Chinese medicine decoction capable of treating excessive-cold type stomachache effectively
CN103263632A (en) * 2013-04-18 2013-08-28 成都绿迪科技有限公司 Traditional Chinese medicine formula for treating phlegm-accumulating-type globus hystericus

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102716449A (en) * 2012-06-18 2012-10-10 天津开发区经经新优技术产品开发有限公司 Chinese patent drug and traditional Chinese medicine decoction capable of treating excessive-cold type stomachache effectively
CN103263632A (en) * 2013-04-18 2013-08-28 成都绿迪科技有限公司 Traditional Chinese medicine formula for treating phlegm-accumulating-type globus hystericus

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
梅核气汤治疗咽部神经官能症疗效观察与护理;喻海燕;《现代中西医结合杂志》;20000630;第9卷(第11期);1076 *

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