CN103585262A - Sophora alopecuroides L alkaloid preparation for preventing and curing livestock ectoparasite disease - Google Patents
Sophora alopecuroides L alkaloid preparation for preventing and curing livestock ectoparasite disease Download PDFInfo
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- CN103585262A CN103585262A CN201310403876.6A CN201310403876A CN103585262A CN 103585262 A CN103585262 A CN 103585262A CN 201310403876 A CN201310403876 A CN 201310403876A CN 103585262 A CN103585262 A CN 103585262A
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Abstract
The invention relates to a Sophora alopecuroides L alkaloid preparation for preventing and curing livestock ectoparasite disease. The external insecticidal acaricide provided by the invention can kill Psoroptes cuniculi after being diluted for 300-400 times, the cure rate can reach 100%, and the effective residual period of the drug can be kept for more than 7 days.
Description
Technical field
The invention belongs to field of veterinary, in particular to a kind of Sophora alopecuroides alkali preparation of preventing and treating ectozoa of domestic animals disease.
Background technology
Ectozoa of domestic animals disease is to parasitize by acaricide, itch mite, louse, Ticks etc. the chronic parasitic dermatosis that domestic animal body surface causes, infected animal be take skin, and violent pruritus, depilation, eczematoid dermatitis occur is main clinic symptoms, the infectiousness with height, often cause in a short time that domestic animal jumpbogroup infects, causing ill domestic animal depilation, poor growth, fodder grass rate of returns when low, serious, to cause its death, is one of Major Diseases of aquaculture.
This disease of past mainly relies on chemical insecticide to carry out such as organophosphorus insecticide, organochlorine insecticide, organonitrogenous insecticide etc. of outer bath treatment, although their insecticidal powers are strong, has residual hazard, has a strong impact on livestock products quality, is detrimental to health.Now by plant source Biocidal acaricide, replaced gradually.Because plant source biology is in natural, with environmentally compatible, can in environment, degrade or metabolism is simple native compound, an its active ingredient carbon containing, hydrogen, three kinds of elements of oxygen, the end product of clearing up in environment is carbon dioxide and water, this in chemosynthesis external insecticidal/acaricidal agent extremely difficulty reach.Chemosynthesis insecticidal/acaricidal agent is the foreign substance of environment substantially, is often difficult for clearing up rapidly in environment, is detained even lastingly.In the production of pollution-free food, Organic food, clearly regulation can be used the plant source biological insecticides as matrine.In recent years along with the raising of people's living standard, the increase of health perception, pollution-free food, Organic food is more and more subject to people's favor, researchs and develops green organic Pesticides and veterinary drugs efficient, nontoxic, noresidue and has caused domestic and international expert's great attention.At present existing evidence Alkaloids From Sophora Alopecuroides L has stronger toxic action to various plants insect and ectozoa of domestic animals.
Herba Sophorae alopecuroidis is distributed widely in the ground such as the Inner Mongol, Ningxia, Gansu, Xinjiang in NORTHWEST CHINA area.Producing region, whole nation area is about more than 180 ten thousand hm
2, wild resource distribution area is wide, and reserves are large, and population advantage is outstanding, awaits comprehensive development and utilization.Herba Sophorae alopecuroidis containing many breed organisms alkali such as: aloperine (Aloperine), sophoridine (Sopho radine), sophoramine (Sophoram in), sophocarpine (Sophocarpine), matrine (M at rine), oxymatrine (O xymat rine) etc. they to ectozoa of domestic animals all have in various degree stomach kill, repellent action, and safety, noresidue are that organic beef and mutton is produced the plant source Biocidal acaricide raw material that must use.Yet existing Alkaloids From Sophora Alopecuroides L can't meet the demand of actual production for the toxic action of ectozoa of domestic animals, the result of use that how further to improve Alkaloids From Sophora Alopecuroides L is this area technical problem urgently to be resolved hurrily.
Summary of the invention
For above-mentioned situation, the object of this invention is to provide a kind of efficient control ectozoa of domestic animals suffering of illness bean or pea alkaloid formulations, in order to realize object of the present invention, intend adopting following technical scheme:
One aspect of the present invention relates to a kind of Sophora alopecuroides alkali preparation of preventing and treating ectozoa of domestic animals disease, and described preparation contains Herba Sophorae alopecuroidis total alkali 4-6 weight portion, sodium lauryl sulphate 4-6 weight portion, dehydrated alcohol 0.8-1.2 weight portion, and distilled water is appropriate.
In a preferred embodiment of the present invention, described preparation contains or does not contain other composition.
In another aspect of this invention, also relate to described preparation and kill the application in the medicine of psoroptes cuniculi in preparation.
After external insecticidal/acaricidal agent 300-400 of the present invention doubly dilutes, can kill psoroptes cuniculi, cure rate can reach 100%, and the effective residual period of medicine on animal body can maintain more than 7 days.
The specific embodiment
Below in conjunction with the specific embodiment, the present invention is described in more detail.
Herba Sophorae alopecuroidis total alkali 5 weight portions, sodium lauryl sulphate 5 weight portions, dehydrated alcohol 1 weight portion, distilled water is added to 100 weight portions, in 40 ℃ of water-baths, 800r/min stirs 15min, after 24 hours, observe solution, solution still the effective content of clear and Herba Sophorae alopecuroidis total alkali without significant change.
Test drug:
The veterinary institute trial-production of plant source domestic animal external insecticidal/acaricidal agent Inner Mongol farming and animal husbandry academy of science.500 milliliters/bottle of specifications, effective ingredient 5%.
Worm demodicid mite is clean: the precious biological company limited in the Holy Land, Shandong produces.500 milliliters/bottle of specifications, effectively become.Divide content 25%, lot number 20110321
Test method:
By buying the ill rabbit coming, be divided into immediately 5 groups, 5 every group.1 group is test group, and 2 groups is matched group.1 group sprays treatment with 300 times of diluents of Herba Sophorae alopecuroidis total alkali plant source domestic animal external insecticidal/acaricidal agent; With worm demodicid mite, only treat for 2 groups, use by specification.Before treatment, should remove hard crust and dirt on affected part.7 days, 14 days viewing test results.As within 7 days, observed, find that there is the pain of itching, and to treat for the second time while finding acarid alive.
Result is judged:
+: there is the pain of itching, can find acarid alive.
±: the pain of itching obviously alleviates, and can find the acarid in half palsy
-: without itching pain, can not find the acarid of living.
Result of the test: see the following form
Conclusion:
(1) by above-mentioned test, can find out that take Herba Sophorae alopecuroidis total alkaloids is can to kill psoroptes cuniculi after the plant source domestic animal external insecticidal/acaricidal agent 300-400 of principal agent development doubly dilutes, cure rate can reach 100%.
(2) test 1 group, when within 7 days, observing, find no the pain animal that itches, 5 experimental animals all do not find acarid alive, illustrate with plant source domestic animal external 300 times of dilutions of insecticidal/acaricidal agent (167ppm) and spray, and the effective residual period of medicine on animal body can maintain more than 7 days
The above, be only the specific embodiment of the present invention, but protection scope of the present invention is not limited to this, and any variation of expecting without creative work or replacement, within all should being encompassed in protection scope of the present invention.Therefore, protection scope of the present invention should be as the criterion with the protection domain that claims were limited.
Claims (4)
1. the application of Herba Sophorae alopecuroidis total alkaloids in control ectozoa of domestic animals disease.
2. prevent and treat the Sophora alopecuroides alkali preparation of ectozoa of domestic animals disease, described preparation contains Herba Sophorae alopecuroidis total alkali 4-6 weight portion, sodium lauryl sulphate 4-6 weight portion, dehydrated alcohol 0.8-1.2 weight portion, and distilled water is appropriate.
3. Sophora alopecuroides alkali preparation according to claim 2, described preparation does not contain other composition.
4. the Sophora alopecuroides alkali preparation described in claim 2 or 3 is killed the application in the medicine of psoroptes cuniculi in preparation.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310403876.6A CN103585262A (en) | 2013-08-31 | 2013-08-31 | Sophora alopecuroides L alkaloid preparation for preventing and curing livestock ectoparasite disease |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310403876.6A CN103585262A (en) | 2013-08-31 | 2013-08-31 | Sophora alopecuroides L alkaloid preparation for preventing and curing livestock ectoparasite disease |
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| CN103585262A true CN103585262A (en) | 2014-02-19 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201310403876.6A Pending CN103585262A (en) | 2013-08-31 | 2013-08-31 | Sophora alopecuroides L alkaloid preparation for preventing and curing livestock ectoparasite disease |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1180074A (en) * | 1997-02-18 | 1998-04-29 | 山东农业大学 | Extraction of sophora alopecuroides extract and its composition |
| CN1650710A (en) * | 2005-02-18 | 2005-08-10 | 李建中 | Insecticide composition containing methylamino Avermectin and matrine |
-
2013
- 2013-08-31 CN CN201310403876.6A patent/CN103585262A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1180074A (en) * | 1997-02-18 | 1998-04-29 | 山东农业大学 | Extraction of sophora alopecuroides extract and its composition |
| CN1650710A (en) * | 2005-02-18 | 2005-08-10 | 李建中 | Insecticide composition containing methylamino Avermectin and matrine |
Non-Patent Citations (2)
| Title |
|---|
| 付明哲等: "中药对螨病的治疗作用及其机理研究进展", 《动物医学进展》 * |
| 罗万春等: "苦豆子生物碱对小菜蛾体内部分杀虫剂代谢酶活性的影响", 《昆虫学报》 * |
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Application publication date: 20140219 |