CN1035802C

CN1035802C - Constipation medicine "shenshenwan"

Info

Publication number: CN1035802C
Application number: CN 92107607
Authority: CN
Inventors: 张思佳; 常越萍; 王宁; 徐德宝
Original assignee: NANJING HOSPITAL AIR FORCE PLA
Current assignee: NANJING HOSPITAL AIR FORCE PLA
Priority date: 1992-06-15
Filing date: 1992-06-15
Publication date: 1997-09-10
Anticipated expiration: 2007-06-15
Also published as: CN1076618A

Abstract

The present invention provides a formula for 'Shenshen' pills capable of curing constipation and a preparation method. The formula for 'Shenshen' pills changes the traditional formula taking cathartic as a main part; after heterophylly falsestarwort roots, mulberry fruits, polygonatum, peach seeds, tuber fleeceflower roots, etc. are pulverized and mixed, the mixture is blended with honey to prepare the pills. The formula for 'Shenshen' pills collect the methods of supplementing Qi, nourishing Yin, nourishing blood, moisturizing intestine, promoting the dispersion function of the lung and dredging viscera, invigorating the kidney and moistening dryness into one dosage, mainly carries out supplementing, and has a peculiar curative effect on curing atonic constipation. The effective rate reaches 98% in clinic, the cure rate reaches 32%, no side effect is generated after people take the pill for a long term, and the pill is accompanied with the efficiency of body building.

Description

Constipation medicine "shenshenwan"

The present invention relates to compound Chinese medicinal preparation, particularly a kind of " shenshenwan " prescription and preparation method for the treatment of constipation.

Current, aged tendency of population has become worldwide problem.Old people's chronic disease will increase as the sickness rate of cardiovascular disease, diabetes, malignant tumor, brain and organ of locomotion degenerative disorders, and these senile disease is usually with constipation.Constipation brings very big misery and harm for old people's body and mind, and when the old people exerted oneself defecation, cerebral blood flow lowered, and can faint, and the hyperpietic can cause cerebrovascular accident, and myocardial infarction can be died suddenly ...

Treatment constipation both at home and abroad at present, except that psychology and Diet Therapy, Drug therapy mainly is the various dissimilar cathartics of utilization.Though can treat acute and chronic constipation as anthraquinone class medicine, because of containing tannic acid astriction is arranged, can produce the secondary constipation; As white oil,, take the absorption that can influence vitamin A, O, K, phosphorus and calcium for a long time in the emollient cathartic owing to hinder the absorption of liposoluble substance; The Chinese medicine that has, fierce as Folium Sennae, DACHENGQI TANG diarrhea inducing, the old people can not tolerate; The clinical normal discovery of Fructus Cannabis Bolus can produce drug resistance behind the clothes for a long time.The saline cathartic that has can cause electrolyte disturbance, and the former capital should not be taken for a long time, and said medicine can only respite to the treatment constipation and can not cure.

The objective of the invention is to overcome the deficiency of said medicine, a kind of good effect is provided, long-term use without side effects can be cured constipation and have concurrently and necessarily be kept fit the prescription and the preparation method of new drug-" shenshenwan " that act on.

Main points of the present invention are to become " rushing down " to be " benefit ", select Radix Pseudostellariae (or Radix Codonopsis, the Radix Astragali, Radix Panacis Quinquefolii) 2～10% for use, Rhizoma Polygonati Odorati (or Herba Dendrobii, pollen, the Radix Rehmanniae) 9～30%, Fructus Mori (or Fructus Ligustri Lucidi) 4.5～15%, Radix Glehniae (or Bulbus Lilii) 0～15%, Radix Asparagi (or Radix Ophiopogonis) 0～10%, Semen Armeniacae Amarum (or Semen Pruni) 2～10%, Radix Polygoni Multiflori 6～20%, Radix Angelicae Sinensis 0～15%, Semen Persicae (or Fructus Cannabis) 0～10%, Fructus Lycii 0～10%, Herba Cistanches 4.5～15%, Semen Cuscutae 0～15%, Fructus Aurantii Immaturus 5～15%, Natrii Sulfas 2～10%.More than Radix Pseudostellariae, Rhizoma Polygonati Odorati, Fructus Mori are monarch in the prescription, supplementing QI and nourishing YIN, the kidney invigorating key spleen; Be aided with Radix Adenophorae (Radix Glehniae), Radix Asparagi, Semen Armeniacae Amarum lung moistening, promote the production of body fluid, the Radix Polygoni Multiflori, Radix Angelicae Sinensis, Semen Persicae nourishing blood and promoting blood circulation, loosening bowel to relieve constipation in order to large intestine; Assistant is moisturized with Fructus Lycii, Herba Cistanches, Semen Cuscutae the kidney invigorating and essence nourishing, warming YANG, the Fructus Aurantii Immaturus intestinal stasis relieving of regulating the flow of vital energy; Natrii Sulfas is messenger drug hard masses softening and resolving simply, through ailing place.Preparation method can clean Chinese medicine, uniform mixing after the weighing, pulverize separately, makes honeyed pill with the Mel fusion; Also Radix Pseudostellariae, Radix Glehniae, Radix Asparagi, Fructus Aurantii Immaturus, Radix Angelicae Sinensis, Radix Polygoni Multiflori, Semen Armeniacae Amarum, Semen Persicae and mirabilite powder can be broken into fine powder, all the other medicines of respectively distinguishing the flavor of decoct with water, and decocting liquid concentrates and adds Mel makes concentrated little general ball with above-mentioned fine powder fusion again.In the prescription, Radix Pseudostellariae, Rhizoma Polygonati Odorati, Fructus Mori, Semen Armeniacae Amarum, Radix Polygoni Multiflori, Herba Cistanches, Fructus Aurantii Immaturus and Natrii Sulfas eight flavors are basic medicine, and all the other each flavors can add as one sees fit, to increase effect.

Embodiment 1 crosses 100 mesh sieves, mix homogeneously then with Radix Pseudostellariae 250g, Rhizoma Polygonati Odorati 750g, Fructus Mori 375g, Radix Glehniae 375g, Radix Asparagi 250g, Semen Armeniacae Amarum 250g, Radix Polygoni Multiflori 500g, Radix Angelicae Sinensis 375g, Semen Persicae 250g, Fructus Lycii 250g, Herba Cistanches 375g, Semen Cuscutae 375g, Fructus Aurantii Immaturus 375g, Natrii Sulfas 250g pulverize separately.With requirement Mel heating, remove floating foam and impurity again, refine in becoming in 20～30 minutes sweet; Add refined honey 100g by every 100g drug powder, be processed into big honeyed pills, the heavy 10g of every ball makes about 1000 of big honeyed pills altogether, is finished medicines with honeyed pill packing, sterilization, the medicine inspection of making at last.

Embodiment 2: get Radix Pseudostellariae 300g, Rhizoma Polygonati Odorati 950g, Fructus Mori 475g, Radix Glehniae 475g, Semen Armeniacae Amarum 300g, Semen Persicae 300g, Radix Polygoni Multiflori 650g, Fructus Lycii 300g, Herba Cistanches 475g, Fructus Aurantii Immaturus 475g, Natrii Sulfas 300g makes 1000 of the great honeyed pill of 10g by example 1 same step.

Embodiment 3: get Radix Pseudostellariae 400g, Rhizoma Polygonati Odorati 1200g, Fructus Mori 600g, Semen Armeniacae Amarum 400g, Radix Polygoni Multiflori 800g, Herba Cistanches 600g, Fructus Aurantii Immaturus 600g, Natrii Sulfas 400g make 1000 of the great honeyed pill of 10g by example 1 same step.

Embodiment 4: take by weighing each medicine by example 1, Radix Pseudostellariae, Radix Glehniae, Radix Asparagi, Fructus Aurantii Immaturus, Radix Angelicae Sinensis, Radix Polygoni Multiflori, Semen Armeniacae Amarum, Semen Persicae, mirabilite powder are broken into fine powder to 100 order, uniform mixing, all the other each medicines add water and did not have powder to decoct secondary, each 3 hours, the secondary decocting liquid merged, and filtered the back and was concentrated into proportion 1.20～1.50 with slow fire, press 4%～20% of concentrated solution weight and add refined honey, make little general ball with above-mentioned fine powder fusion then.

Embodiment 5: takes by weighing each medicine by example 2 Radix Pseudostellariae, Semen Armeniacae Amarum, Semen Persicae, Radix Polygoni Multiflori, Radix Glehniae, Fructus Aurantii Immaturus, mirabilite powder is broken into fine powder to 100 order, and uniform mixing, all the other each medicines decoct with water, and make little general ball by example 4 same steps.

Embodiment 6: takes by weighing each medicine by example 3, Radix Pseudostellariae, Semen Armeniacae Amarum, Radix Polygoni Multiflori, Fructus Aurantii Immaturus, mirabilite powder is broken into fine powder to 100 order, and uniform mixing, all the other each medicines decoct with water, and make little general ball by example 4 same steps.

The shenshenwan that utilizes prescription of the present invention to make, the medicine source is abundant, system Do simply, with supplementing qi and nourishing yin, enriching the blood and moisturizing the intestine, the logical internal organs of a surname's lung, kidney tonifying Moisturize all methods among potion, take benefit as usefulness. With domestic and international existing rushing down Medicine has relatively remedied the deficiency that they can only the respite symptom, and is right Treat senile constipation and have unique curative effect, clinical effective rate reaches 98%, healing reaches 32%, long-term use without side effects, and have concurrently Keep fit effect.

Claims

1, a kind of preparation method with reinforcement treatment constipation medicine shenshenwan is characterized in that:

Formula proportion is with Chinese medicine: Radix Pseudostellariae 2～10%, Rhizoma Polygonati Odorati 9～30%, Fructus Mori 4.5～15%, Semen Armeniacae Amarum 2～10%, Radix Polygoni Multiflori 6～20%, Herba Cistanches 4.5～15%, Fructus Aurantii Immaturus 5～15%, Natrii Sulfas 2～10%, Radix Glehniae 7.5%, Radix Asparagi 5%, Radix Angelicae Sinensis 7.5%, Semen Persicae 5%, Fructus Lycii 5%, Semen Cuscutae 7.5% are formed, preparation method is: all kinds of Chinese medicines are cleaned, after the weighing, pulverize separately becomes the fine powder mix homogeneously, and honey added in the medicated powder fusion and makes big honeyed pills during Mel heating was refined.

2, the preparation method of treatment constipation medicine shenshenwan according to claim 1, it is characterized in that: said medicine is crushed to 100 orders, and the raw honey heating refining time is 20～30 minutes, and the ratio that adds refined honey and medicated powder is 1: 1.