CN101904982B - Traditional Chinese medicine combination used for treating chronic eczema by treating lungs and preparation thereof - Google Patents
Traditional Chinese medicine combination used for treating chronic eczema by treating lungs and preparation thereof Download PDFInfo
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Abstract
The invention provides a traditional Chinese medicine combination used for treating chronic eczema by treating lungs and a preparation thereof, belonging to the field of traditional Chinese medicines. The traditional Chinese medicine combination takes radix polygonati officinalis and asparagus as main components and fructus cannabis, lily, folium mori and ginseng as accessory components, so that the efficacies of all the components generate synergia to play the functions of dispersing wind heat of lung, skin and hair and relaxing bowel so as to eliminate toxicity, nourishing Yin and clearing heat so as to nourish the lung, benefiting vital energy so as to nourish the lung and treating the lung and the skin together, thereby achieving the purpose of treating the chronic eczema. Clinical tests prove that the traditional Chinese medicine combination of the invention has good therapeutic effect for the chronic eczema; and researches find that the traditional Chinese medicine combination of the invention has explicit remission and therapeutic effect for skin and appearance progeria, acne, rosacea, chloasma, freckle, chronic facial recurrent dermatitis, ataxia telangiectasia, pityriasis simplex, psoriasis, acute eczema, xerosis cutis syndrome, excessive heat problem of five facial sense organs and the like.
Description
Technical field
The invention belongs to the field of Chinese medicines, relate to a kind of being used for, relate in particular to a kind of Chinese medicine composition and preparation thereof for the treatment of chronic eczema by the foster lung of lung heat clearing by controlling the Chinese medicine composition and the preparation thereof of lung treatment chronic eczema.
Background technology
Chronic eczema is a kind of allergic skin disease that is caused by internal and external factor.Chronic eczema is many by the transformation that shows effect repeatedly of acute eczema, subacute eczema.The primary disease course of disease is touching, and is heavy when light during the state of an illness, the constant moon or several years, even many decades is not healed.Its clinical manifestation is that illing skin soaks into plumpness, and rough surface is kermesinus or companion's pigmentation, and skin lesion mostly is the limitation speckle, is common in brothers, shank, the fossa cubitalis, breast, pudendum, anus etc. and locates clear-cut margin.The course of disease is chronic, is several months or several years, also can be because of the stimulation acute attack.
Interior-deficiency is the basis of chronic eczema morbidity.There are many names of disease to refer to eczema in fact in the TCM Document, are included among skin ulcer, tinea, the wind.All belong to the primary disease scope as acute eczema, eczema of ear, eczema of scrotum, atopic eczema etc.The argumentation of " multiple arteries and veins too then makes us Sheng Re and pain in the skin, is contamination " is just arranged in " element ask beautiful machine really hide an opinion piece of writing ".The record of symptom and method of treatment is arranged in " Medical Treasures of the Golden Chamber carbuncle sore acute appendicitis contamination abnormal pulse card is also controlled ", as " acute eczema, the Rhizoma Coptidis powder master it." it is generally acknowledged, chronic eczema many because of blood-deficiency and wind-dry, damp and hot accumulate long-pending due to.
Ancient Chinese medicine doctor proposes, the theory of " lung governing skin and hair ", " fur person, lung close also ", " having outside the Zhu Neibi Xingqi ".The dermopathic medicine of being put down in writing in the Gu doctor mat of motherland's medical science of treatment is mostly gone into lung meridian, as Radix Asparagi, Bulbus Lilii, the Radix Angelicae Dahuricae etc.In conjunction with modern cytobiology, fetology, immunology scheduling theory, observe clinically that lung lesion and dermatosis influence each other, dermatosis is controlled from the lung opinion, has embodied the organic conception of the traditional Chinese medical science.
The lung skin is with root homology, coexistence common prosperity; Lung-heat lung poison spreads unchecked, the deficiency of both QI and YIN of lung; It is that skin is hindered that lung is hindered.Therefore, lungs are unbalance is the main root of chronic eczema.Modern medicine study proves, many dermatosiss, and as xerosis cutis, pimple, coarse, plump, desquamation, blue veins exposure, illing skin pigmentation etc., unbalance relevant with lungs all.Therefore, pneumonopathy can be controlled skin, and the skin disease can be controlled lung.
Chronic eczema is generally discussed and is controlled by wet, heat, wind, yet our research thinks that the lung qi Yin bivacuity is the basis of chronic eczema morbidity, and lung-heat lung poison is the basic of chronic eczema morbidity.Lung-heat lung poison works along both lines is rule of treatment so treatment is to set upright and to remove.
Summary of the invention
The purpose of this invention is to provide a kind of by controlling the Chinese medicine composition of lung treatment chronic eczema.
Another object of the present invention provides the preparation of this Chinese medicine composition.
The present invention is used for by controlling the Chinese medicine composition of lung treatment chronic eczema, is to be key component with Rhizoma Polygonati Odorati, Radix Asparagi, is aided with Fructus Cannabis, Bulbus Lilii, Folium Mori, Radix Ginseng, the oral preparations that is prepared into by the common process and the adjuvant of pharmaceutics.
In above-mentioned each medicine, Rhizoma Polygonati Odorati, sweet, be slightly cold, attach to the lung and stomach meridians nourishing YIN to relieve dryness, promoting the production of body fluid to quench thirst.Being generally used for lung stomach-Yin wound, cough caused by dryness-heat, dry throat and mouth, interior-heat quenches one's thirst.It not only can regulate immunity modern study, and has the function of scavenger interior free yl, slow down aging, anti-hypoxia, inhibition tumor, clinically can be used for treating chloasma usually, regulates skin water oil imbalance state etc.
Radix Asparagi, sweet, bitter, cold, return lung, kidney channel, nourishing YIN to relieve dryness, lung heat clearing are promoted the production of body fluid.Be generally used for that dryness of the lung dry cough, pertussis expectorant are sticking, dry throat and mouth, dryness of the intestine constipation.It not only can protect myocardial function and liver function modern study, and has antibacterial, the antitumor action of antiinflammatory, and ancients are with its product as longevity, and it has the ability of fabulous solution xerosis cutis problem through the clinical research proof for we.
Fructus Cannabis, sweet, flat, return spleen, stomach, large intestine channel, moisturize the laxation relieving constipation.Be generally used for blood deficiency and depleted fluid, dryness of the intestine constipation.Modern study confirms that Fructus Cannabis is major reason of " township of world's longevity " Guangxi crust horse area people's life-prolonging.In addition just because of it also has function of relaxing bowel, and motherland's medical science thinks that " the lung and the large intestine being interior-exteriorly related ", endogenous toxin go from large intestine, and lung-heat lung poison is from going, and skin care is from therein.
Bulbus Lilii, sweet, cold, GUIXIN, lung meridian, nourishing YIN to relieve dryness, clearing away heart-fire for tranquillization.Tradition is used for deficiency of YIN dry cough, sputum mixed with blood, fidgets due to deficiency palpitation with fear, insomnia and dreamful sleep, absentminded.It has antitumaous effect modern study, also has resisting fatigue, anoxia enduring, function of relieving cough and calming asthma, and through our long-term follow research, Bulbus Lilii has good nourishes rough skin, brightens the function of skin moistening.
Folium Mori, sweet, bitter, cold, return lung, Liver Channel, dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, liver heat removing and eyesight improving.It is dim-sighted that tradition is used for anemopyretic cold, lung-heat type cough, dizziness headache, conjunctival congestion.Prove that through clinical research Folium Mori can be treated the various skin disease that comprises chloasma.
Radix Ginseng, sweet, little hardship, flat is returned spleen, lung, heart channel, and strongly invigorating primordial QI, multiple arteries and veins take off admittedly, invigorating the spleen to benefit the lung, promote the production of body fluid, calm the nerves.Be generally used for that weak body and prostration, cold extremities faint pulse, insufficiency of the spleen lack of appetite, the deficiency of the lung are breathed with cough, lung Tianjin is thirsty, the empty win of prolonged illness, palpitation with fear insomnia, sexual impotence cold womb.Modern study is a lot, and it not only can improve multiple effects such as memory, endocrine regulation, resisting fatigue, adjusting immunity, anticancer, antiinflammatory, antiviral, and clear and definite delaying senility function is arranged.
With the passing of time the many delays of chronic eczema must consume gas the moon of lung, so should note supplementing QI and nourishing YIN.To mend its void, Bulbus Lilii, Radix Asparagi, Rhizoma Polygonati Odorati yin nourishing are with Sheng Qijin with Radix Ginseng lung benefiting gas in the present invention; Chronic eczema must have pyretic toxicity to be jammed in lung, so impel pyretic toxicity to go from large intestine with the Fructus Cannabis loosening bowel to relieve constipation, Folium Mori are evacuated pyretic toxicity and removed from skin.
The present invention is on medicine is formed, with Rhizoma Polygonati Odorati, Radix Asparagi is key component, is aided with Fructus Cannabis, Bulbus Lilii, Folium Mori, Radix Ginseng, collaborative wind heat of playing its thin lung fur altogether, loosening bowel to relieve constipation with toxin expelling, nourishing YIN and clearing away heat to support lung, QI invigorating lung moistening to support lung, the lung skin is ruled together, to reach the purpose of treatment chronic eczema.
By a large amount of tests and clinical summary, each crude drug of Chinese medicine composition of the present invention all has good effect to various face dermatosis in the scope of following weight portion:
Rhizoma Polygonati Odorati 10-50 part Radix Asparagi 10-50 part Fructus Cannabis 1-5 part
Bulbus Lilii 1-5 part Folium Mori 1-5 part Radix Ginseng 1-5 part.
The optimum ratio scope is as follows:
Rhizoma Polygonati Odorati 15-30 part Radix Asparagi 15-30 part Fructus Cannabis 2-3 part
Bulbus Lilii 4-5 part Folium Mori 2-3 part Radix Ginseng 1-3 part.
The present invention is used for by controlling the Chinese medicine composition of lung treatment chronic eczema, can adopt the common process and the adjuvant of pharmacy of Chinese materia medica to be prepared into various oral preparations, as electuary, tablet, capsule, pill (comprising the watered pill, honeyed pill, dragee, soft gelatin capsule, drop pill, enteric coated pill or drop pill etc.), oral solutions, medicinal tea etc.
A large amount of clinical researches prove that the present invention has good therapeutic effect to chronic eczema.Be clinical observation material below.
1, clinical data
The object of observation:
1. pruritus: be characterized in the persistence pruritus, relying on takes sb's mind off sth also can't solve, and when quieting down, pruritus can be aggravated, and forms the state of Secondary cases aggravation, persistence pruritus.Observe 20 examples, man, each 10 example of woman.
2. pleomorphism: the erythra that eczema shows is polymorphic, can be divided into former dermexanthesis and secondary rash.Pimple, blister etc. are arranged in the former dermexanthesis, erosion is arranged in the secondary rash, ooze out etc., former dermexanthesis and secondary rash take place in patient usually simultaneously.Observe 20 examples, man, each 10 example of woman.
3. delay property: eczema is outbreak repeatedly easily, delays another position from a position, and symptom is difficult for eliminating.Observe 20 examples, man, each 10 example of woman.
4. exudative: the erythra position has transudate.Observe 20 examples, man, each 10 example of woman.
5. general property: eczema can betide the arbitrary position of whole body.Observe 20 examples, man, each 10 example of woman.
6. the chronic course of disease: the time heavy when light, Chang Fanfu is acute or subacute outbreak, during especially with psychentonia for very.Be confined to a certain position more, locate as hands, shank, the fossa cubitalis, scrotum, cysthus etc., the border is obvious, and inflammation is not outstanding.Observe 20 examples, man, each 10 example of woman.
Case is from during 1997～1999, and the age is between 17～59 years old.Have both above-mentioned various clinical symptoms.Inactive other Therapeutic Method during the treatment.Symptom and sign all disappear and with examine 1 year not the recidivist be recovery from illness, disappear 40% or more and with examining recurrence but more preceding alleviator for effectively, it is invalid disappearing below 40% and recurring the former.
2, Therapeutic Method
Capsule medicine of the present invention: every 0.5 gram, every day 3 times, each 5, serveing on 30 days is a course of treatment.1～2 course of treatment of patients with mild, 3～5 courses of treatment of moderate patient, 4～6 courses of treatment of severe patient treatment.Food such as fasting raw food, zest, seafood, wine and Wine, Carnis caprae seu ovis, Carnis Anseris domestica during the treatment.
3, therapeutic outcome
Whole statistics recovery from illness 78 examples account for 65%; Effective 31 examples account for 25.8%; Invalid 11 examples account for 9.2%.Wherein the female patient therapeutic effect is better than the male, and no matter its delay property chronic eczema effect of sex is the poorest.
4, medical record for example
Ma, woman, 22 years old, 1997-03-22 first visit.Chronic eczema arises from 17 years old, and the pimple and the papulovesicle of whole body point-like erythema and foxtail millet grain size, part are oozed and grown incrustation, stretching side with both shoulders, last back and upper arm, shank is play, and it is coarse that both shoulders portion and shank are stretched the side pachyderma, and scratch is obvious, the affected part acute pruritus is suffered untold misery.And plain easily diseases caused by exogenous pathogenic factor, lustreless complexion, Sleep hyperhidrosis, constipation with dry stool, fatigue and weak, the few tongue of red tongue.Card belongs to deficiency of both QI and YIN, scorchingly hot resistance lung.Control with supplementing QI and nourishing YIN the heat extraction poison of dispelling.Medicinal: lung lavage capsule (Rhizoma Polygonati Odorati 150g, Radix Ginseng 60g, Radix Asparagi 90g, Bulbus Lilii 150g, Folium Mori 120g, Fructus Cannabis 100g), grind to the powder altogether and adorn No. 0 capsule (every 0.5 gram), every day 3 times, each 5, it is ruddy beautiful to serve on recovery from illness half a year and skin of face gloss.
Clinical trial also finds, medicine of the present invention has clear and definite alleviation and therapeutical effect to skin appearance senilism disease, acne, rosacea, chloasma, freckle, chronic facial area recurrent dermatitis, telangiectasia, pityriasis simplex, psoriasis, acute eczema, xerosis cutis syndrome, the facial area face problem etc. of getting angry.
The specific embodiment
The preparation of embodiment 1, tablet medicine of the present invention
Prescription: in weight portion:
10 parts of Rhizoma Polygonati Odorati, 10 parts of Radix Asparagis, 1 part of Fructus Cannabis, 1 part of Bulbus Lilii, 1 part on Folium Mori, 1 part of Radix Ginseng.
Technology: the common process and the adjuvant that prepare tablet by pharmacy of Chinese materia medica are prepared into tablet.
The preparation of embodiment 2, capsule medicine of the present invention
Prescription: in weight portion:
15 parts of Rhizoma Polygonati Odorati, 15 parts of Radix Asparagis, 2 parts of Fructus Cannabiss, 3 parts of Bulbus Liliies, 1 part on Folium Mori, 1 part of Radix Ginseng.
Technology: the common process and the adjuvant that prepare capsule by pharmacy of Chinese materia medica are prepared into capsule.
The preparation of embodiment 3, granules medicine of the present invention
Prescription: in weight portion:
30 parts of Rhizoma Polygonati Odorati, 20 parts of Radix Asparagis, 1 part of Fructus Cannabis, 5 parts of Bulbus Liliies, 5 parts on Folium Mori, 1 part of Radix Ginseng.
Technology: the common process and the adjuvant that prepare granule by pharmacy of Chinese materia medica are prepared into granule.
The preparation of embodiment 4, drop pill medicine of the present invention
Prescription: in weight portion:
50 parts of Rhizoma Polygonati Odorati, 20 parts of Radix Asparagis, 3 parts of Fructus Cannabiss, 4 parts of Bulbus Liliies, 5 parts on Folium Mori, 2 parts of Radix Ginsengs.
Technology: the common process and the adjuvant that prepare drop pill by pharmacy of Chinese materia medica are prepared into drop pill.
The preparation of embodiment 5, watered pill medicine of the present invention
Prescription: in weight portion:
40 parts of Rhizoma Polygonati Odorati, 10 parts of Radix Asparagis, 1 part of Fructus Cannabis, 5 parts of Bulbus Liliies, 5 parts on Folium Mori, 1 part of Radix Ginseng.
Technology: the common process and the adjuvant that prepare watered pill by pharmacy of Chinese materia medica are prepared into watered pill.
The preparation of embodiment 6, oral medicine liquid of the present invention
Prescription: in weight portion:
35 parts of Rhizoma Polygonati Odorati, 30 parts of Radix Asparagis, 1 part of Fructus Cannabis, 5 parts of Bulbus Liliies, 5 parts on Folium Mori, 3 parts of Radix Ginsengs.
Technology: the common process and the adjuvant that prepare oral liquid by pharmacy of Chinese materia medica are prepared into oral liquid.
The preparation of embodiment 7, medicinal tea medicine of the present invention
Prescription: in weight portion:
50 parts of Rhizoma Polygonati Odorati, 50 parts of Radix Asparagis, 1 part of Fructus Cannabis, 5 parts of Bulbus Liliies, 5 parts on Folium Mori, 5 parts of Radix Ginsengs.
Technology: the common process and the adjuvant that prepare medicinal tea by pharmaceutics are prepared into medicinal tea.
Claims (8)
1. one kind is used for by controlling the Chinese medicine composition of lung treatment chronic eczema, is the oral preparations that is prepared into by the common process and the adjuvant of pharmaceutics by following bulk drugs:
Rhizoma Polygonati Odorati 10-50 part Radix Asparagi 10-50 part Fructus Cannabis 1-5 part
Bulbus Lilii 1-5 part Folium Mori 1-5 part Radix Ginseng 1-5 part.
2. be used for according to claim 1 by controlling the Chinese medicine composition of lung treatment chronic eczema, it is characterized in that: described each raw material medicines in portions by weight is as follows:
Rhizoma Polygonati Odorati 15-30 part Radix Asparagi 15-30 part Fructus Cannabis 2-3 part
Bulbus Lilii 4-5 part Folium Mori 2-3 part Radix Ginseng 1-3 part.
3. be used for according to claim 1 by controlling the Chinese medicine composition of lung treatment chronic eczema, it is characterized in that: described preparation is a tablet.
4. be used for according to claim 1 by controlling the Chinese medicine composition of lung treatment chronic eczema, it is characterized in that: described preparation is a capsule.
5. be used for according to claim 1 by controlling the Chinese medicine composition of lung treatment chronic eczema, it is characterized in that: described preparation is a pill.
6. be used for according to claim 1 by controlling the Chinese medicine composition of lung treatment chronic eczema, it is characterized in that: described preparation is a granule.
7. be used for according to claim 1 by controlling the Chinese medicine composition of lung treatment chronic eczema, it is characterized in that: described preparation is a medicinal tea.
8. be used for according to claim 1 by controlling the Chinese medicine composition of lung treatment chronic eczema, it is characterized in that: described preparation is an oral liquid.
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