CN103550372B - Medicament for medical abortion - Google Patents
Medicament for medical abortion Download PDFInfo
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- CN103550372B CN103550372B CN201310560959.6A CN201310560959A CN103550372B CN 103550372 B CN103550372 B CN 103550372B CN 201310560959 A CN201310560959 A CN 201310560959A CN 103550372 B CN103550372 B CN 103550372B
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Abstract
The invention relates to a medicament for medical abortion. The medicament for medical abortion is prepared from the following raw materials in parts by weight: tiarella polyphylla, plum blossom, auriculate dichrocephala, sweet-scented osmanthus, blumea megacephala, kousa dogwood, dichocarpum auriculatum, potentilla kleiniana, porana flower, mung bean, purpleflower holly leaf, raphistemma pulchellum, nanocnide, pinfa raspberry root and leaf, orange blossom, earthworm, narrow-leaved lindernia, six-eared blumea, tortoise shell, locust flower, hemistepta lyrata and rhizoma panacis majoris. The medicament for medical abortion has the advantages of easily available raw materials and definite curative effect, and tests show that the effective rate is high and the cost is low.
Description
Technical field
The present invention relates to field of medicaments, relate in particular to a kind of medicament for drug induced abortion.
background technology
Mifepristone is a kind of acceptor levels gestation medicament, and itself and misoprostol successively compatibility are used energy termination of early pregnancy, is a mouthful front comparatively ideal antiearly pregnancy method.Although it is nearly 90% that abortion ratio reaches, the long still an open question that remains at present of vaginal hemorrhage time.
summary of the invention
The object of this invention is to provide a kind of medicament for drug induced abortion.
In order to realize object of the present invention, the invention provides a kind of medicament for drug induced abortion, it is to be made by the material of following weight parts: 6 parts of 3 parts of Herba tiarellae polyphyllaes, 8 parts, Flos Mume, 2 parts of Herba Dichrocephalae auriculataes, 7 parts of Flos Osmanthi Fragrantis, 2 parts of Herba Blumeae clarkei, 2 parts of Dendronenthamia japonica var.chinensis, 3 parts of sow grass, 2 parts of Herba potentillae kleinianae, 5 parts of Radix seu Herba Poranae Racemosaes, 8 parts, Semen phaseoli radiati, 8 parts of Ilex purpurea Hassk.[I.chinensis Sims, 6 parts of Caulis Stelmatocryptonis khasiani, 3 parts of Herba Nanocnides Japonicae, 6 parts of Radix seu Folium Rubi Pinfaensis, 7 parts of Citrus aurantium L. var. amara Engl.s, 5 parts of Pheretimas, 3 parts of Lindernia angustifolia (Benth.) Wettst.s, 2 parts of the Herba Blumeae Laciniataes, 2 parts of Carapax Et Plastrum Testudiniss, 7 parts of Flos Robiniae Pseudoacaciae, 3 parts of Herba Hemisteptae Lyrataies and Rhizoma Panacis Majoris.
Preferably, medicament of the present invention can be made tablet, dispersible tablet, decoction or powder.
In order to understand better the present invention, with reference to < < Chinese medicine voluminous dictionary > > second edition, being described as follows of some crude drug that use in the present invention:
In compositions of the present invention, Herba tiarellae polyphyllae, Flos Mume, Herba Dichrocephalae auriculatae, Flos Osmanthi Fragrantis, Herba Blumeae clarkei are monarch drug; Dendronenthamia japonica var.chinensis, sow grass, Herba potentillae kleinianae, Radix seu Herba Poranae Racemosae, Semen phaseoli radiati, Ilex purpurea Hassk.[I.chinensis Sims are ministerial drug; Caulis Stelmatocryptonis khasiani, Herba Nanocnides Japonicae, Radix seu Folium Rubi Pinfaensis, Citrus aurantium L. var. amara Engl., Pheretima are adjuvant drug; Lindernia angustifolia (Benth.) Wettst., the Herba Blumeae Laciniatae, Carapax Et Plastrum Testudinis, Flos Robiniae Pseudoacaciae, Herba Hemisteptae Lyratae and Rhizoma Panacis Majoris are for making medicine; Compositions of the present invention is brought into play drug effect best by monarch synergism.
Raw material of the present invention is easy to get, determined curative effect, and high through evidence effective percentage, cost is low.
The specific embodiment
Below the invention will be further described for the description by the specific embodiment, but this is not limitation of the present invention, those skilled in the art are according to basic thought of the present invention, can make various modifications or improvement, but only otherwise depart from basic thought of the present invention, all within the scope of the present invention.
The preparation of embodiment 1 decoction of the present invention
Get 6 grams of 3 grams of Herba tiarellae polyphyllaes, 8 grams, Flos Mume, 2 grams of Herba Dichrocephalae auriculataes, 7 grams of Flos Osmanthi Fragrantis, 2 grams of Herba Blumeae clarkei, 2 grams of Dendronenthamia japonica var.chinensis, 3 grams of sow grass, 2 grams of Herba potentillae kleinianae, 5 grams of Radix seu Herba Poranae Racemosaes, 8 grams, Semen phaseoli radiati, 8 grams of Ilex purpurea Hassk.[I.chinensis Sims, 6 grams of Caulis Stelmatocryptonis khasiani, 3 grams of Herba Nanocnides Japonicae, 6 grams of Radix seu Folium Rubi Pinfaensis, 7 grams of Citrus aurantium L. var. amara Engl.s, 5 grams of Pheretimas, 3 grams of Lindernia angustifolia (Benth.) Wettst.s, 2 grams of the Herba Blumeae Laciniataes, 2 grams of Carapax Et Plastrum Testudiniss, 7 grams of Flos Robiniae Pseudoacaciae, 3 grams of Herba Hemisteptae Lyrataies and Rhizoma Panacis Majoris, add 8000 milliliters, water, under the condition of reflux, heat 4 hours.Filter, filtrate is decoction of the present invention.
Experimental example
1.1 physical data
The object of observation is women gestation 82 examples, age 20-41 year, and pregnant time 1-4 time, parity 0-2 time, menolipsis 35-49 days, all makes a definite diagnosis uterine pregnancy through B ultrasonic, and pregnant capsule diameter <3cm, without the contraindication of using mifepristone, misoprostol.Be divided into Chinese drug-treated group 42 examples, matched group 40 examples.Age between two groups, state of an illness there was no significant difference.
Matched group is in oral mifepristone 25mg (1) on an empty stomach in morning every day, and oral 25rn on an empty stomach again after 12 hours, serve on 3 days, and the 4th day morning be Given oral Misoprostol 600 μ g (3) on an empty stomach.The decoction making in the oral embodiment 1 of Chinese drug-treated group is treated, and wherein one day 2 times, each oral 100 milliliters, treats 4 days.
Efficacy determination: artificial abortion: after medication, in 6 hours, complete pregnant tissue is discharged, and B ultrasonic confirms in utero noresidue, without surgical intervention person; Incomplete abortion: after medication, in 6 hours, part pregnant tissue is discharged, B ultrasonic confirms in utero to have residual, implements clearing heat in the pericardium patient; Ineffective abortion: discharge without pregnant tissue in 6 hours after medication, B ultrasonic confirms to be in utero pregnant capsule, need stop with operation.Result following table 1.
Clinical efficacy comparison [n (%)] after table 1 liang group treatment
As can be seen here, Chinese drug-treated group artificial abortion rate 95.2%, matched group is 87.5%, two groups relatively there were significant differences (P<0.05), Chinese drug-treated group vaginal hemorrhage time <7 days, account for 85.7%, matched group is 37.5%, two group, and relatively there were significant differences (P<0.05).This shows, uses decoction of the present invention to improve artificial abortion rate, has obviously shortened the vaginal hemorrhage time after medicine stream.
Untoward reaction and toxic and side effects monitoring
By detect the patient of Chinese drug-treated group blood pressure, pulse, whether occur feeling sick, vomiting, dizzy clinical symptoms judge untoward reaction.Set human normal systolic pressure between 90-140mmHg, diastolic pressure is between 60-90mmHg, human normal pulse is 60-100 beat/min, during treating, measure the patient's of Chinese drug-treated group blood pressure, pulse, find that the blood pressure and pulse recording is all within normal range, the phenomenon that does not exceed normal interval occurs, and there is no to occur nauseating, vomiting, dizzy clinical symptoms.This illustrates that pharmaceutical composition of the present invention does not have obvious untoward reaction, and then proves that this medicine does not have obvious toxic and side effects for human body.
Claims (1)
1. for a medicament for drug induced abortion, it is characterized in that it is to be made by the material of following weight parts: 6 parts of 3 parts of Herba tiarellae polyphyllaes, 8 parts, Flos Mume, 2 parts of Herba Dichrocephalae auriculataes, 7 parts of Flos Osmanthi Fragrantis, 2 parts of Herba Blumeae clarkei, 2 parts of Dendronenthamia japonica var.chinensis, 3 parts of sow grass, 2 parts of Herba potentillae kleinianae, 5 parts of Radix seu Herba Poranae Racemosaes, 8 parts, Semen phaseoli radiati, 8 parts of Ilex purpurea Hassk.[I.chinensis Sims, 6 parts of Caulis Stelmatocryptonis khasiani, 3 parts of Herba Nanocnides Japonicae, 6 parts of Radix seu Folium Rubi Pinfaensis, 7 parts of Citrus aurantium L. var. amara Engl.s, 5 parts of Pheretimas, 3 parts of Lindernia angustifolia (Benth.) Wettst.s, 2 parts of the Herba Blumeae Laciniataes, 2 parts of Carapax Et Plastrum Testudiniss, 7 parts of Flos Robiniae Pseudoacaciae, 3 parts of Herba Hemisteptae Lyrataies and Rhizoma Panacis Majoris.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310560959.6A CN103550372B (en) | 2013-11-12 | 2013-11-12 | Medicament for medical abortion |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310560959.6A CN103550372B (en) | 2013-11-12 | 2013-11-12 | Medicament for medical abortion |
Publications (2)
| Publication Number | Publication Date |
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| CN103550372A CN103550372A (en) | 2014-02-05 |
| CN103550372B true CN103550372B (en) | 2014-10-08 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201310560959.6A Expired - Fee Related CN103550372B (en) | 2013-11-12 | 2013-11-12 | Medicament for medical abortion |
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Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104758626B (en) * | 2015-04-28 | 2016-01-20 | 李良 | A kind of medicament for drug induced abortion |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1370594A (en) * | 2002-03-01 | 2002-09-25 | 庞耀贤 | Chinese mediicne for treating women's menalgia, pelvic infection and vaginitis |
| CN1439420A (en) * | 2003-03-19 | 2003-09-03 | 周荣生 | Oral Chinese medicinal contraceptive medicine |
| CN103349760A (en) * | 2013-07-31 | 2013-10-16 | 苏海英 | Medicine for treating colporrhagia after abortion |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100962587B1 (en) * | 2007-10-02 | 2010-06-11 | 동국대학교 산학협력단 | A method for fermentation of natural plants and herbal medicines, a fermented product prepared therefrom and a paharmaceutical composition, a cosmetic compositon and a food composition comprising the product |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1370594A (en) * | 2002-03-01 | 2002-09-25 | 庞耀贤 | Chinese mediicne for treating women's menalgia, pelvic infection and vaginitis |
| CN1439420A (en) * | 2003-03-19 | 2003-09-03 | 周荣生 | Oral Chinese medicinal contraceptive medicine |
| CN103349760A (en) * | 2013-07-31 | 2013-10-16 | 苏海英 | Medicine for treating colporrhagia after abortion |
Non-Patent Citations (6)
| Title |
|---|
| 中医辨证治疗药物流产后阴道出血90例;李开琼;《齐齐哈尔医学院学报》;20081231;第29卷(第13期);第1589页 * |
| 何华.生化汤加味治疗药流后出血65例.《光明中医》.2002,第17卷(第98期),第59-60页. |
| 古时的中草药避孕法;郭振东;《东方食疗与保健》;20060131(第1期);第50页 * |
| 李开琼.中医辨证治疗药物流产后阴道出血90例.《齐齐哈尔医学院学报》.2008,第29卷(第13期),第1589页. |
| 生化汤加味治疗药流后出血65例;何华;《光明中医》;20021231;第17卷(第98期);第59-60页 * |
| 郭振东.古时的中草药避孕法.《东方食疗与保健》.2006,(第1期),第50页. |
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| CN103550372A (en) | 2014-02-05 |
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