CN1370594A - Chinese mediicne for treating women's menalgia, pelvic infection and vaginitis - Google Patents

Abstract

The Chinese medicine is prepared with rose mallow, spatholobus stem, tassel flower, Herba Hedyotis Diffusae, downy rosemyrtle root and other Chinese medicinal materials and is in tablet, capsule, granule, oral liquid and other forms. It has the functions of clearing away, diuresis, diminishing inflammation, killing bacteria, dispersing blood clots, etc. and is used to treat women's menoxenia, menalgia, pelvic infection, vaginitis and other women's inflammatinos with high curative effect.

Description

A kind of treatment dysmenorrhes, pelvic inflammatory disease, colpitic Chinese medicine

Technical field:

The present invention relates to a kind of medicine for the treatment of gynaecopathia, especially a kind of treatment dysmenorrhes, pelvic inflammatory disease, colpitic Chinese medicine.

Background technology:

Women's all one's life, menoxenia, dysmenorrhea, the inflammation of various urogenital systems such as vaginitis, pelvic inflammatory disease, endometritis, adnexitis etc. are frequently-occurring disease and commonly encountered diseases, common is women's leukorrhagia.At present, on the medicine of this class disease of treatment, effectively Chinese medicine is less, is with the treatment of Western medicine antibiotics clinically substantially, clinical findings, and with this type of gynaecopathia of western medicine, not only weak curative effect, easily recurrence, and also side effect is big.Particularly in order to diseases such as the dysmenorrhea that tackles the women, leukorrhagia, the more little or basic inefficacy of curative effect.Thereby, very undesirable on the medical market at present with the various genitourinary system inflammations and the inferior effect of TONGJINGDAI of Western medicine antibiotic therapy gynecological, there is not specific Chinese patent medicine again.Clinically make decoction oral with the Chinese physician with disease foreign side, inconvenience.

Summary of the invention:

Purpose of the present invention, to inherit the medical heritage of motherland exactly, utilize Chinese herbal medicine resource advantage all over the mountains and plains, develop the Chinese medicine of a kind of specially good effect, safety, convenience, inexpensive, pure natural, under the TONGJINGDAI in order to the treatment women, vaginitis, pelvic inflammatory disease, endometritis, commonly encountered diseases frequently-occurring diseases such as adnexitis remedy defectives such as the Western medicine toxic and side effects is big.

The present invention is that to select Chinese herbal medicine for use be raw material, through repeated screening, develop.Dosage form is made generally in sugar coated tablet, also can be made into capsule, electuary etc.The proportioning of its material component is:

Folium Malloti Apeltae 3～18 weight portion Radix Urenae Lobataes 2～20 weight portion Caulis Spatholobis 3～50 weight portions

Herba Duchesneae Indicae 2～30 weight portion Herba Thlaspiss 1.5～15 weight portions

Herba Hedyotidis Diffusae 3～20 weight portion Radix Rhodomyrtis 2.5～25 weight portions

Technological process:

Take by weighing above-mentioned medical material section or section, put and extract in the pot, add 60% ethanol that is about 8 times of amounts of medical material, heating and refluxing extraction 1.5～2.5 hours.Emit extracting solution, add 60% ethanol be about 8 times of amounts of medical material again, heating and refluxing extraction 1.5 hours is emitted extracting solution, and extracted twice liquid merges, filtered and recycled ethanol, and concentrating and making relative density is 13 fluid extract, standby.

Get the fluid extract portion, add the starch of three deals, the dextrin of a deal, mix homogeneously, moistening with 80% an amount of ethanol, make soft material, granulate again (14 mesh sieve), in 70～80 ℃ of oven dry, with 16 mesh sieve granulate, tabletting (is used the 10mm drift, every heavy 0.5 gram), sugar coating, packing, outer package, it is qualified to inspect by ready samples, gets finished product.

Advantage of the present invention:

1, efficient.Chinese medicine of the present invention is in order to diseases such as treatment women dysmenorrhoea leukorrhagia, pelvic inflammatory disease, vaginitis, endometritis, adnexitis, and cure rate is up to about 90%.

2, safety, convenience.Chinese medicine of the present invention has no side effect, and drug safety is made the tablet transportation, takes care of, carries, takes all very convenient.

3, pure natural.The present invention all adopts medical herbs, and pure natural has been avoided the Western medicine synthetic side effect of industrial chemicals.

4, prescription is concise, and medicine is selected, suits etiology and pathogenesis fully.

5, feed distribution is wide, obtains the simple no specific (special) requirements of processing easily.Existing herbal pharmaceutical brand-name computer tool equipment all can be produced, and technological process is uncomplicated, and raw material is many, the source is easy, and low, the comprehensive industrial cost of price is cheap, has the market competitiveness.

The specific embodiment:

The present invention selects for use 7 flavor Chinese herbal medicine to form altogether: Folium Malloti Apeltae, Radix Urenae Lobatae, Caulis Spatholobi, Herba Duchesneae Indicae, Radix Rhodomyrti, Herba Thlaspis, Herba Hedyotidis Diffusae.

Folium Malloti Apeltae (see Guangzhou air force compile " Chinese herbal medicine handbook 1969.12.1 commonly used)

Recognition feature: Euphorbiaceae Mallotus

Another name: the wild paulownia of Folium Malloti Apeltae flour halberd

1. shrub or dungarunga are high 2～5 meters, sprig, and petiole, blade back, inflorescence and fruit are all by white

Fine hair.

2. leaf alternate, wealthy oval, blade face bottle green, back side canescence.

3. spend little, spike; Give birth on the top or axil is given birth to.Fruit spheroidal has the soft thorn of feather.

Nature,taste and action: pained flat.The soothing liver-QI clearing heat and expelling damp of invigorating blood circulation

Radix Urenae Lobatae (see Guangzhou air force compile " Chinese herbal medicine handbook 1969.12.1 commonly used)

Recognition feature: the Malvaceae Herba urenae procumbentis belongs to

Another name: silly mother-in-law's Eight Diagrams Radix Clematidis Clarkeanae

1. upright branch undershrub, high about 1 meter, drape over one's shoulders pubescence less, the peel of stem multifilament.

2. leaf alternate, tool long handle, phyllopodium subcircular, palmate 3～5 shallow splitting, leaf tip oval or wealthy

Lanceolar, the irregular sawtooth in edge, 3～7 of veins.

3. spend cerise, five lobes, the likeness in form Flos persicae singly is born in axil, and fruit has agnail.

Nature,taste and action: sweet cold.Expelling wind and removing dampness heat-clearing and toxic substances removing promoting blood circulation to remove blood stasis Caulis Spatholobi (see Guangzhou air force compile " Chinese herbal medicine handbook 1969.12.1 commonly used) recognition feature: Sargentodoxaceae Saggentodoxa another name: mountain Caulis Sargentodoxae Caulis Sargentodoxae Caulis seu Radix Schisandrae Henryi

1. wooden big liana, reach 10 surplus rice, the stem brown, circle has striped, cross-section surface current is red

Color juice.

2. leaf alternate, finger-like three pin lobules, the oval lobule is given birth on the top, and middle arteries and veins deflection is inboard.

3. spend axil to give birth to, yellow or Huang Luse, fruit ovum shape Long Circle, the surface is by white lead.

Nature,taste and action; Pained.Empty the meridian dredging wind-damp dispelling Herba Duchesneae Indicae (see Guangzhou air force compile " the Chinese herbal medicine handbook 1969.12.1 commonly used) recognition feature of enriching blood: the Compositae Herba Duchesneae Indicae belongs to another name: the wild cabbage mustard of YEXIAHONG

1. annual upright draft, high 10～50 centimetres, adularescent is dredged hair.

2. phyllopodium gives birth to, the lyrate division, and blade tip multitude capitiform, the leaf egg shape lanceolar, what embrace phyllopodium

Base, the irregular sawtooth of leaf margin, blade back aubergine.

3. top repiece locusta, tool long handle, flower aubergine.

Nature,taste and action: bitter cool.Heat-clearing and toxic substances removing antiinflammatory diuretic Herba Thlaspis (see Guangzhou air force compile " Chinese herbal medicine handbook 1969.12.1 commonly used) recognition feature: Compositae herba thlaspis genus another name: Xi dish

1. annual herb is high about 60 centimetres, by pubescence.

2. leaf alternate, blade face green, the irregular sawtooth of leaf margin, the white fine hair of blade back.

3. umbel is given birth on the top.

Nature,taste and action: bitter cool.Clearing away heat-damp and promoting diuresis blood circulation promoting and blood stasis dispelling Herba Hedyotidis Diffusae (see Guangzhou air force compile " Chinese herbal medicine handbook 1969.12.1 commonly used) recognition feature: Rubiaceae cerastium another name: the Herba Hedyotidis Diffusae JIAMENGCAO grass that looses

1. the humidogene draft of throwing oneself on the ground is about 25 centimetres, and stem has rib.

2. leaf is to life, and is linear, is about 1～3 centimetre, nearly stockless.

3. floral white, one or in pairs axil give birth to short handle.

4. fruit is little, is similar to Punica granatum L. outward.

Nature,taste and action: sweet cold.The heat-clearing and toxic substances removing diuresis of blood circulation promoting

Radix Rhodomyrti (see Guangzhou air force compile " Chinese herbal medicine handbook 1969.12.1 commonly used)

Recognition feature: Myrtaceae Myrtus

Another name: the mountain is twisted with the fingers the hilllock and is twisted with the fingers

1. shrub is high 1～2 meter, the close living pubescence of twig.

2. leaf is to life, and ellipse, base go out three arteries and veins, and the blade face is smooth, and the back of the body is by white undercoat.

3. spend aubergine, fruit is cup-shaped seemingly, ripe fruit aubergine, and it is sweet edible to distinguish the flavor of.

4. root, leaf puckery.

Nature,taste and action: sweet puckery flat.Astringent therapy dampness dispelling, collateral-activating blood-enriching tranquillizing

Dialectical opinion is controlled (principle, medical knowledge)

The women is if there is retention of damp-heat in the interior the place, multiple abscess chong channel conception vessel, and rich knot vessels of the uterus stays the stasis of blood and the blockage of menstruation that arrives is obstructed, and stagnation of QI and blood may bring about pain forms dysmenorrhea; Or because of damaged by excess of seven emotions, then water is wet does not transport for the impairment of the spleen, the then strongly fragrant and heat-transformation of impairing the liver, with wet rich knot, damp invasion of lower energizer and directly violate Three Yin Channels of Foot and uterus forms leukorrhagia, all diseases of pain over the perineum pruritus, all diseases of endometritis, pelvic inflammatory disease, adnexitis, vaginitis due to promptly women's urogenital system infects.The damp and hot stasis of blood knot of the cause of disease is controlled with clearing away heat-damp and promoting diuresis the painful pain relieving of dispelling.The present invention selects the bitter sweet cold of Folium Malloti Apeltae, Radix Urenae Lobatae, Herba Duchesneae Indicae for use, and it is hot and suffocating clearly that clearing away heat-damp and promoting diuresis, eliminating inflammation and expelling toxin make it part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels uterus, and water is wet gets profit, and pyretic toxicity must remove; And with Caulis Spatholobi, Herba Hedyotidis Diffusae, Herba Thlaspis, Radix Rhodomyrti blood circulation promoting and blood stasis dispelling, tonifying blood and regulating menstruation, thus clearing away heat-damp and promoting diuresis become altogether, stasis-dispelling and pain-killing, the good recipe of various inflammation such as treatment dysmenorrhes leukorrhagia, pelvic cavity, vagina, adnexa.

Embodiment:

Example 1

Weighting raw materials Folium Malloti Apeltae 3kg, Radix Urenae Lobatae 2kg, Caulis Spatholobi 5kg, Herba Duchesneae Indicae 3kg, Herba Hedyotidis Diffusae 3kg, Radix Rhodomyrti 2.5kg ， Herba Thlaspis 1.5kg.

With its section, put and extract in the pot, 60% the ethanol that adds about 180kg, heating and refluxing extraction 2 hours adds 60% ethanol of 180kg again, heating and refluxing extraction 1.5 hours, emit extracting solution, merge extracted twice liquid, filtered and recycled ethanol, concentrating and making relative density is 1.3 fluid extract 4.4kg, standby.

Get fluid extract, and add starch 13.2kg, dextrin 4.4kg, mix homogeneously, moistening with 80% ethanol of 350ml, make soft material, granulate (crossing 14 mesh sieves), in 70～80 ℃ of oven dry, with 16 mesh sieve granulate, tabletting (is used the 10mm drift, every heavy 0.5 gram), sugar coating, packing, outer package, it is qualified to inspect by ready samples, gets finished product.

Embodiment 2:

Take by weighing

Folium Malloti Apeltae 18kg, Radix Urenae Lobatae 20kg, Caulis Spatholobi 50kg, Herba Duchesneae Indicae 30kg ， Herba Thlaspis 15kg, Herba Hedyotidis Diffusae 30kg, Radix Rhodomyrti 2.5kg.

Be cut into segment and put into the extraction pot, the ethanol that adds 1600kg 60%, heating and refluxing extraction 2.5 hours, 60% ethanol that adds 160kg again, heating and refluxing extraction 1.5 hours is emitted extracting solution, merge extracted twice liquid, filtered and recycled ethanol, concentrating and making relative density is 1.3 fluid extract 45kg, standby.

Get fluid extract, and add starch 135kg, dextrin 45kg, mix homogeneously, moistening with 80% ethanol of 3000ml, make soft material, granulate (crossing 14 mesh sieves), in 70～80 ℃ of oven dry, with 16 mesh sieve granulate, tabletting (is used the 10mm drift, every heavy 0.5 gram), sugar coating, packing, outer package, it is qualified to inspect by ready samples, gets finished product.

The treatment clinical efficacy is given an example:

Case 1

Beam *, the woman 39 years old, lives new street, Shan Xin town, Xingye County, Guangxi No. 2.The patient examined on March 6th, 1999, readme through first three the sky begin and menstrual period the lower abdomen pain with tenderness, angina abdominis under the paroxysm, abdominal part is scorching hot, the waist distending pain, the time nausea and vomiting is arranged, be in a cold sweat, hands and feet coolness, dim red through color, matter is thick piece, and leukorrhagia is sticky and yellow at ordinary times, oliguria with reddish urine, slippery and rapid pulse.

Laboratory, other auxiliary examination:

One, the menses prostaglandin is measured

Can show unusually and increase＞435ng/L;

Two, auxiliary examination

The pelvic cavity gynecologial examination is no abnormal

Diagnosis: the mutual junction type dysmenorrhea of the damp and hot stasis of blood

Treatment: begin to take new drug of the present invention on March 7th, 1999, fry in shallow oil the decoction clothes, serve on three, from the pain relief of taking medicine on the 7th, clothes to 9 day do not have pain, abdominal part is scorching hot, waist is bloated, all card shapes of vomiting disappear, and are smooth and easy through row, the potion of taking medicine back every day, continuous clothes 10 days, this side observed 1 year, and every menstrual phase pain is extremely slight, and does not have caking, do not had leukorrhagia normally, through color, dysmenorrhea is cured.

Case 2;

Slowly * *, the woman 40 years old, lives north, Beiliu City, Guangxi boccaccio No. 32

The patient went to a doctor on May 12nd, 2000, the readme fever with aversion to cold, and hypogastralgia, tenderness, vaginal secretions increases, and yellow skin is thick, and is dirty smelly, frequent micturition, urgent micturition, causalgia, constipation, yellowish urine.

Check:

One, woman's inspection

Vaginal congest, secretions is many, is purulence, and trachelopanus is lifted pain obviously, and body of uterus is bigger, limitation of activity, tenderness, both sides, uterus tenderness is obvious.

Two, laboratory and other auxiliary examination

1, routine blood test: numeration of leukocyte obviously raises, and neutrophilic leukocyte obviously raises, and erythrocyte sedimentation rate is accelerated.

2, pathogen culture.The visible gonococcus of hemoculture, streptococcus.

3, B-type ultrasonography: inflammatory exudation is arranged in the pelvic cavity.

Diagnosis: acute pelvic inflammatory disease

Treatment: on May 13rd, 2000 began to take new drug of the present invention, make the decoction clothes, two doses of day clothes serve on 12, beginning cold and heat in second day from taking medicine must end, took medicine 6 days, stomachache is removed, and frequent micturition dysurea card shape disappears, take medicine to the 8th day transference cure, the woman examines, lab testing is normal, renews clothes and deals with problems arising from an accident for 8 doses, does not see recurrence to October calendar year 2001.

Claims (1)

1, a kind of treatment dysmenorrhes, pelvic inflammatory disease, colpitic Chinese medicine is characterized in that containing the following raw material of proportioning:

Folium Malloti Apeltae 3～18 weight portion Radix Urenae Lobataes 2～20 weight portion Caulis Spatholobis 3～50 weight portions

Herba Duchesneae Indicae 2～30 weight portion Herba Thlaspiss 1.5～15 weight portions

Herba Hedyotidis Diffusae 3～20 weight portion Radix Rhodomyrtis 2.5～25 weight portions.