CN103549939B - Close-contact ultrasonic coupling adaptive device for photoacoustic/thermoacoustic mammary gland imaging detection, and detection method of adaptive device - Google Patents
Close-contact ultrasonic coupling adaptive device for photoacoustic/thermoacoustic mammary gland imaging detection, and detection method of adaptive device Download PDFInfo
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Abstract
The invention relates to a close-contact ultrasonic coupling adaptive device for photoacoustic/thermoacoustic mammary gland imaging detection, and belongs to the technical field of photoacoustic/thermoacoustic imaging. The adaptive device comprises a detection cup, a coupling liquid spray device and an air pressure regulating device, wherein a to-be-detected breast is placed in the detection cup with the shape and the size corresponding to the breast; the coupling liquid spray device is connected with the detection cup, and can spray ultrasonic coupling liquid between the to-be-detected breast and the detection cup; and the air pressure regulating device is connected with the detection cup by an air guide tube, and inhales or deflates between the to-be-detected breast and the detection cup. The adaptive device has the advantages that the adaptive device is good in matching degree, safe, comfortable, easy to replace, and high in automation degree.
Description
Technical field
The present invention relates to optoacoustic/thermal acoustic imaging technical field, be specifically related to a kind of breast cancer device, particularly a kind of intimate contact ultrasonic coupling device and detection method thereof.The present invention can be assemblied in microwave thermal sound breast examination device and opto-acoustic imaging devices.
Background technology
Optoacoustic/the thermal acoustic imaging of pulse laser/microwave-excitation is a kind of novel Dynamic Non-Destruction Measurement closely risen during the decade, because it has safety and nondestructive, and high-contrast, the advantage such as high-resolution and high imaging depth and receive increasingly extensive concern.When certain material is subject to pulse laser/microwave exposure, material absorbing laser/microwave energy can cause transient temperature rise, if the pulsewidth of laser/microwave is enough narrow, thermal diffusion can not be there is in the energy absorbed within the pulse duration, now as adiabatic expansion can be regarded, heat energy will be converted into mechanical energy and radiate with hyperacoustic form, be optoacoustic/thermoacoustic effect.According to the equation of heat conduction and wave equation: the optoacoustic/hot acoustical signal of generation not only with excitaton source relating to parameters, also relevant with the electromagnetic absorption characteristic of material.When excitaton source is determined, ultrasonic signal is mainly derived from the inner absorption difference to laser/microwave of material.Actual for concrete application---breast tumor inspection, main component due to normal breast to be measured is fat, and the microwave absorption coefficient of fat is less, the continuous growth of malignant tumor tissue, more juicy, ion, capillary proliferation must be attended by, the electrolyte balance of inside tumor of these substance changes, causes electromagnetic strong absorption.Therefore the dielectric constant between tumor tissues and the breast normal to be measured based on fatty tissue and electrical conductivity differ greatly, all at about 10 times.Calculated by electromagnetism and learn, larger than normal breast to be measured about 6 times of the microwave absorption of tumor tissues.Equally due to the rapid amplification of cancerous cell, cause microvascularly sharply increasing, and the light of hemoglobin to specific band in blood has strong absorption.Therefore tumor tissues and the larger light absorption difference of fatty tissue is caused.These just provide theoretical basis and foundation for breast carcinoma microwave thermoacoustic imaging and photoacoustic imaging.Human breast interior lights/microwave absorption differential image can be provided by optoacoustic/thermal acoustic imaging system, accurately and intuitively reflect inside of human body situation, for scientific research provides abundant material and information.
The main difficulty that above-mentioned imaging system instrumentation faces has: research and development have high launching efficiency and high-resolution ultrashort pulse microwave source; Design high sensitivity ultrasound acquisition system and efficiently acoustical coupling device.The design mainly for be the ultrasonic coupling system of ultrasound acquisition system front end.Coupled system is mainly ultrasonicly coupled to supersonic sounding acquisition system efficiently by what excite, reduces the impact on excitaton source as far as possible simultaneously.In reality detects, because the ultrasonic signal amplitude of laser/microwave-excitation is very little, usually in mv level and following, the efficient coupling of such ultrasonic signal between different system seems particularly important, so in order to realize efficient coupling device, effective way be to reduce due to the different parts of instrument internal as far as possible between laser/microwave loss of producing of coupling and ultrasound wave loss.
Microwave is as electromagnetic wave, and its propagation law meets as follows: Helmholtz fluctuation equation
Wherein E is electric field intensity, and electromagnetic wave propagation rule is exactly the dielectric constant u of research medium in fact
0with pcrmeability ε
0the Changing Pattern of these two parameter temporal, space and frequency.
Electromagnetic wave loss mainly comprises reflection loss and absorption loss.Absorption loss is decided by attenuation quotient, and its numerical value is directly proportional to the square root of conductivityσ and pcrmeability, is inversely proportional to the square root of dielectric constant, and reflection loss depends mainly on the natural impedance difference of transmission medium both sides, and the larger reflection of difference is larger.Natural impedance equals the square root of pcrmeability and dielectric constant ratio.The metallic conductor that dielectric constant is very little will be the good reflector of microwave, be unfavorable for penetrating of microwave, will consider light loss equally, answer the material that selective light permeability is high.As transparent modified epoxy resin just all has good penetrance to light/microwave.
Pulse laser/microwave is organized transient absorption after coupling device, because thermoelastic effect produces ultrasonic.The ultrasonic echo signal as detection system, realizes ultrasonic Min. loss decay, is the key technology that optoacoustic/thermal acoustic imaging needs to solve.Ultrasonic losses comprises reflection loss and absorption loss.Reflection loss depends mainly on the acoustic impedance Z of medium, when ultrasound wave is from acoustic impedance Z
1medium vertical incidence acoustic impedance Z
2medium, its sound intensity reflection coefficient of medium interface r that two kinds of acoustic impedance Z are different is:
From above formula: the acoustic impedance Z difference on both sides, interface is larger, and reflection loss is larger, as on air-soft tissue interface, sound intensity reflection coefficient reaches 0.99.And our medical ultrasonic probe takes to be close to skin usually, the method for smearing ultrasonic coupling liquid carrys out the transitionality coupling that air-out realizes acoustic impedance, close with skin with the acoustic impedance of contact skin, reduces ultrasonic losses with this.
Absorption loss depends mainly on the acoustic attenuation constant of material.Acoustic attenuation constant is relevant with propagated ultrasonic frequency, and the acoustic attenuation constant of different acoustic window materials has very large difference at different frequencies, and frequency is higher, and acoustic attenuation constant is larger.Conventional acoustic window material is mainly used in the ultrasonic probe matching layer (silicone rubber, epoxy resin) of the sound absorber (polyurethane) of military submarine and industry, medical use, and the former has good underwater sound entrant sound effect, but its material is flexible material.The latter can meet the demands in hardness, but the ultrasonic dominant frequency excited 5MHz(due to material is near 5MHz) ULTRASONIC ABSORPTION loss is excessive, can not meet our requirement.In conjunction with actual demand, there is Gao Guang/electromagnetic wave and penetrate efficiency and ultrasonic coupling efficiency, and have the material of certain degree of hardness to be the coupling material being applicable to optoacoustic/thermal acoustic imaging.
There is not the ultrasonic coupling adaptive device being exclusively used in mammary gland optoacoustic/thermal acoustic imaging and detecting in prior art, and when detecting, laminating defective tightness, affects Detection results.
Summary of the invention
For the technical problem existed in prior art, the object of the invention is: a kind of human breast structure that adapts to is provided, can effectively, close-coupled electromagnetic wave and hyperacoustic intimate contact ultrasonic coupling adaptive device of detecting for mammary gland optoacoustic/thermal acoustic imaging and detection method thereof.
In order to achieve the above object, the present invention adopts following technical scheme:
For the intimate contact ultrasonic coupling adaptive device that mammary gland optoacoustic/thermal acoustic imaging detects, comprise and detect cup, coupling liquid liquid-jet device and barometric control unit; Breast to be measured is placed in the corresponding detection cup of shape, size; Coupling liquid liquid-jet device connects with detection cup and at breast to be measured with detect between cup and spray into ultrasonic coupling liquid; Barometric control unit connects with detection cup and at breast to be measured with detect air-breathing or venting between cup.After adopting this structure, detect cup can to fit very well whole breast to be measured, breast to be measured is not yielding or displacement in testing process, simultaneously under the dual function of ultrasonic coupling liquid and negative pressure, realize the close contact detecting cup and breast to be measured, the hot acoustic pressure that such breast tissue is launched can penetrate cup preferably and couplant outside cup is transferred to detector of sound, improves sound detection efficiency.
Detection cup support breast to be measured is adopted to carry out ultrasonic coupling; Described detection cup comprises cup and cup tail; Cup is and udder shape to be measured, bowl structure that size is corresponding, and cup is fixedly connected with cup tail; Cup tail is connected by airway with coupling liquid liquid-jet device or barometric control unit, and cup tail and airway are that detachable-type sealed is connected.After adopting this structure, the cup of different size (containing height and diameter) can be made in advance, to adapt to different udder shapes, applied range; Simultaneously cup tail adopts with airway that being threaded spins coordinates, and replacing facilitates.Cup tail and cup screw tighten the complete bowl assembling structure of rear formation, and breast to be measured is held in effect.
The material of cup and cup tail is modified epoxy.After adopting this structure, the acoustic impedance of this material and tissue relatively, can obtain best Detection results.Wherein, a kind of commercially available polymeric material of modification, its attenuation quotient under the supersonic frequency of 5MHz is 3.64dB/cm, and hardness reaches shore 83D, and acoustic impedance is about 1.43 × 10
5/ (g/cm
2.s), this material is mainly used in ultrasonic probe now.Cup and cup tail adopt modified epoxy material, can reach best ultrasonic coupling effect.
Barometric control unit comprises: the air pump completing air-breathing or deflating action; Control the barostat of air pump action; Real-Time Monitoring detects atmospheric pressure value in cup, and testing result is transferred to the air pressure acquisition sensor of barostat.After adopting this structure, effectively to detection cup and breast evacuation to be measured, can ensure that it fits tightly.Barostat is a miniature processing system, can control air pump action according to setup parameter and air pressure acquisition sensor signal.Air pump effect comes air-breathing or venting according to barostat instruction, realizes breast and fit tightly with detection cup, do not have the air gap.
Coupling liquid liquid-jet device comprises device for atomizing liquid, liquid containing bottle and conduit; Device for atomizing liquid is connected with liquid containing bottle by conduit, and ultrasonic coupling liquid is contained in liquid containing bottle.After adopting this structure, conveniently can spray ultrasonic coupling liquid between detection cup and breast to be measured, ensure that it fits tightly.
Coupling liquid liquid-jet device and barometric control unit integrated setting; Air pump connects with device for atomizing liquid and realizes hydrojet action of exitting; After detection cup connects an airway, connecting with coupling liquid liquid-jet device or barometric control unit by changing the interface connected with the airway other end, realizing venting hydrojet or aspiratory action.After adopting this structure, structure is simplified, easy to operate.Coupling liquid is medical supersonic coupling liquid, and its effect strengthens ultrasonic permeability, realizes tissue and mates with the acoustic impedance between modified epoxy, and contributes to squeezing away the air between breast to be measured and detection cup.
The intimate contact ultrasonic coupling adaptive device detected for mammary gland optoacoustic/thermal acoustic imaging and annular array checkout gear with the use of; Annular array checkout gear comprises polynary annular array detector, pulse laser/microwave source, precision displacement platform and coupling slot; Polynary annular array detector rings around the periphery detecting cup, and passes through precision displacement platform upper and lower translation; Pulse laser/microwave source is positioned at and detects immediately below cup and towards detection cup emission pulse laser/microwave; Mineral oil is filled, in the upper end of pulse laser/microwave source, polynary annular array detector and detection cup being immersed in coupling slot.After adopting this structure, breast tissue is connected with cup by ultrasonic coupling liquid, and cup has isolated mineral oil and breast tissue simultaneously, achieves safety and sanitation, detects easily, can carry out Precision measurement and location to breast tissue.
The intimate contact ultrasonic coupling adaptive device detected for mammary gland optoacoustic/thermal acoustic imaging also comprises a detection platform; Detect the opening up of cup to be fixed in the installing port that detection platform is offered.After adopting this structure, human body only needs prostrate in detection platform, is placed on by breast and detects in cup, and without the need to doctor's manual scanning breast to be measured, testing result is reliable, and testing process human body sensory is comfortable.
The opening detecting cup arranges sealing ring, and when breast to be measured is placed in detection cup, sealing ring is close to breast to be measured and is detected cup.After adopting this structure, ensure breast to be measured further and detect fitting tightly of cup.
For the detection method of the intimate contact ultrasonic coupling adaptive device that mammary gland optoacoustic/thermal acoustic imaging detects, comprise the steps: by coupling liquid liquid-jet device, ultrasonic coupling liquid to be sprayed between breast to be measured and detection cup, the gas between breast to be measured and detection cup is drawn again by barometric control unit, under the effect of negative pressure and ultrasonic coupling liquid, realize breast to be measured and detect the close contact of cup, finally by with the use of annular array checkout gear scan.Adopt in this way, ultrasonic coupling liquid and negative pressure dual function, ensure breast and detect fitting tightly of cup; Detect cup simultaneously and can ensure that breast is indeformable in testing process, be not shifted, can not Detection results be affected.
Generally speaking, tool of the present invention has the following advantages:
(1) in apparatus of the present invention, material therefor avirulence, and be applicable to optoacoustic, thermal acoustic imaging two kinds of breast imaging devices simultaneously, be a kind of safe multipurpose checkout gear.
(2) the present invention considers the individual variation of udder shape and udder size and actual detection, and adopt the solid coupled modes of body cup-shaped, in testing process, breast can not be out of shape and be shifted, and overcomes the problem that fluid coupling is easy to deformation and displacement.By the coupling cup of solid shape, easily realize tissue profile to be measured and size is fixed, facilitate the precise positioning of detection, there is novelty and the suitability widely.
(3) in the present invention, cup adopts special material, to light/microwave with ultrasonicly have high permeability, reaches combining closely of breast and cup by coupling liquid nebulizer and pneumatic shuttle.Tool novelty and high coupling efficiency.
(4) regulate cup internal gas pressure by barostat, person to be measured can detect in a kind of pleasant mode; Breast to be measured is stressed less in detection cup, and constriction is not obvious; When being taken out by breast, only need exit and remove vacuum state, whole testing process is felt without discomfort.
(5) apparatus of the present invention system bulk is little, lightweight, working stability, and continuous operating time is long, easy to use, and cost is low, and energy-output ratio is little; Huge impetus is had for the clinical practice realizing optoacoustic/thermal acoustic imaging technology.
(6) testing process automaticity is high.
(7) the present invention achieves the good sound transmission by ultrasonic coupling adaptive device, will organize simultaneously and isolate with mineral oil, and ensure the safety and sanitation of testing process.
Accompanying drawing explanation
Fig. 1 is the position view of the present invention in optoacoustic/hot sound detection system.
Fig. 2 is the partial enlarged drawing that the present invention detects cup.
Fig. 3 is overall structure schematic diagram of the present invention.
Wherein, 1 is shell, and 2 is detect cup, and 3 is polynary annular array detectors, 4 is coupling slots, and 5 is airways, and 6 is barometric control unit and coupling liquid liquid-jet device, and 7 is pulse laser/microwave sources, 8 is precision displacement platforms, and 9 is detection platform, and 10 is data control bus, 11 is acquisition control systems, and 12 is real-time display screens, and 13 is human bodies, 14 is breast to be measured, and 15 is sealing rings, and 16 is air pumps, 17 is barostats, and 18 is air pressure acquisition sensors, and 19 is interfaces.
Detailed description of the invention
Below in conjunction with the drawings and specific embodiments, the present invention will be further described in detail.
For the intimate contact ultrasonic coupling adaptive device that mammary gland optoacoustic/thermal acoustic imaging detects, comprise and detect cup, coupling liquid liquid-jet device, barometric control unit and detection platform.
Detect cup and comprise cup and cup tail, cup is the bowl structure corresponding to udder shape, is fixedly connected with by screw with cup tail, and the tail end of cup tail arranges thread segment so that change.In order to better mate the breast to be measured of different size, should design the cup of different size, it at least comprises and is not limited only to following several: 1, opening diameter 120mm, length 80mm; 2, opening diameter 100mm, length 60mm; 3, opening diameter 80mm, length 40mm.During use, select the detection cup of different model according to breast size to be measured, screw and can use.The material detecting cup is modified epoxy, and thickness is 1mm.The opening detecting cup arranges sealing ring, when breast to be measured is placed in detection cup, sealing ring is close to breast to be measured and is detected cup, the material of sealing ring is rubber, diameter is slightly less than the opening diameter (different with detection cup size difference) detecting cup, there is 0.5mm fillet, medical supersonic coupling liquid should be filled during use to keep excellent sealing effect.
Barometric control unit comprises: the air pump completing air-breathing or deflating action; Control the barostat of air pump action; Real-Time Monitoring detects atmospheric pressure value in cup, and testing result is transferred to the air pressure acquisition sensor of barostat.Coupling liquid liquid-jet device comprises device for atomizing liquid, liquid containing bottle and conduit; Device for atomizing liquid is connected with liquid containing bottle by conduit, and ultrasonic coupling liquid is contained in liquid containing bottle.Coupling liquid liquid-jet device and barometric control unit integrated setting; Air pump connects with device for atomizing liquid and realizes hydrojet action of exitting.After the cup tail of detection cup and airway screw thread spin, connecting with coupling liquid liquid-jet device or barometric control unit by changing the interface connected with the airway other end, realizing venting hydrojet or aspiratory action.
Detection platform offers installing port, detects cup and to be fixed in installing port and opening up.
The intimate contact ultrasonic coupling adaptive device detected for mammary gland optoacoustic/thermal acoustic imaging and annular array checkout gear with the use of.Annular array checkout gear comprises polynary annular array detector, pulse laser/microwave source, precision displacement platform and coupling slot.Polynary annular array detector rings around the periphery detecting cup, and realizes the scanning to breast to be measured by precision displacement platform upper and lower translation; Pulse laser/microwave source is positioned at and detects immediately below cup and to send pulse microwave to detection cup direction; Mineral oil is filled, in the upper end (i.e. the position of transmitted pulse microwave) of pulse laser/microwave source, polynary annular array detector and detection cup being immersed in the coupling slot that shell surrounds.
After barometric control unit and coupling liquid liquid-jet device integrated setting, connected with acquisition control system by data control bus, scanning result shows through real-time display screen.
During use, the detection cup that installation dimension is suitable, human body is prostrate in detection platform, and breast is placed on and detects in cup.Press switch key, extraction gas speed is set by knob, and setting air-breathing atmospheric pressure value.First by the venting jet mode of barostat, by air pump and device for atomizing liquid by ultrasonic coupling liquid even application on breast to be measured, then air-breathing mode is utilized to extract the gas detected in cup, under the combined effect of negative pressure and ultrasonic coupling liquid, realize the close contact of breast and cup, reach the object not having the air gap, effect is to greatest extent through laser/microwave and ultrasound.Next can carry out next step to detect.After pulse laser/microwave source (laser/microwave generator) sends pulse microwave, by mineral oil, detect cup and ultrasonic coupling liquid, irradiation on breast to be measured, because thermoacoustic effect inspires ultrasound wave, instant heating acoustical signal, ultrasonic signal spreads out of from organization internal, through ultrasonic coupling liquid, detect cup and mineral oil, after being received by polynary annular array detector, through Back end data process, reconstruct hot acoustic image, reflection pathological information.
Above-described embodiment is the present invention's preferably embodiment; but embodiments of the present invention are not restricted to the described embodiments; change, the modification done under other any does not deviate from spirit of the present invention and principle, substitute, combine, simplify; all should be the substitute mode of equivalence, be included within protection scope of the present invention.
Claims (9)
1. for the intimate contact ultrasonic coupling adaptive device that mammary gland optoacoustic/thermal acoustic imaging detects, it is characterized in that: comprise and detect cup, coupling liquid liquid-jet device and barometric control unit; Breast to be measured is placed in the corresponding detection cup of shape, size; Coupling liquid liquid-jet device connects with detection cup and at breast to be measured with detect between cup and spray into ultrasonic coupling liquid; Barometric control unit connects with detection cup and at breast to be measured with detect air-breathing or venting between cup;
Described barometric control unit comprises:
-complete the air pump of air-breathing or deflating action,
The barostat of-control air pump action,
-Real-Time Monitoring detects atmospheric pressure value in cup, and testing result is transferred to the air pressure acquisition sensor of barostat.
2. according to the intimate contact ultrasonic coupling adaptive device detected for mammary gland optoacoustic/thermal acoustic imaging according to claim 1, it is characterized in that: adopt detection cup support breast to be measured to carry out ultrasonic coupling; Described detection cup comprises cup and cup tail; Cup is and udder shape to be measured, bowl structure that size is corresponding, and cup is fixedly connected with cup tail; Cup tail is connected by airway with coupling liquid liquid-jet device or barometric control unit, and cup tail and airway are that detachable-type sealed is connected.
3., according to the intimate contact ultrasonic coupling adaptive device detected for mammary gland optoacoustic/thermal acoustic imaging according to claim 2, it is characterized in that: the material of described cup and cup tail is modified epoxy.
4., according to the intimate contact ultrasonic coupling adaptive device detected for mammary gland optoacoustic/thermal acoustic imaging according to claim 1, it is characterized in that: described coupling liquid liquid-jet device comprises device for atomizing liquid, liquid containing bottle and conduit; Device for atomizing liquid is connected with liquid containing bottle by conduit, and ultrasonic coupling liquid is contained in liquid containing bottle.
5., according to the intimate contact ultrasonic coupling adaptive device detected for mammary gland optoacoustic/thermal acoustic imaging according to claim 4, it is characterized in that: described coupling liquid liquid-jet device and barometric control unit integrated setting; Air pump connects with device for atomizing liquid and realizes hydrojet action of exitting; After detection cup connects an airway, connecting with coupling liquid liquid-jet device or barometric control unit by changing the interface connected with the airway other end, realizing venting hydrojet or aspiratory action.
6., according to the intimate contact ultrasonic coupling adaptive device detected for mammary gland optoacoustic/thermal acoustic imaging according to claim 1, it is characterized in that: it and annular array checkout gear with the use of; Annular array checkout gear comprises polynary annular array detector, pulse laser/microwave source, precision displacement platform and coupling slot; Polynary annular array detector rings around the periphery detecting cup, and passes through precision displacement platform upper and lower translation; Pulse laser/microwave source is positioned at and detects immediately below cup and towards detection cup emission pulse laser/microwave; Fill mineral oil in coupling slot, polynary annular array detector and detect in cup is immersed in, pulse laser/microwave source upwards Emission Lasers/microwave below coupling slot, laser/microwave penetration mineral oil uniform irradiation is on breast to be measured.
7., according to the intimate contact ultrasonic coupling adaptive device detected for mammary gland optoacoustic/thermal acoustic imaging according to claim 1, it is characterized in that: it also comprises a detection platform; Detect the opening up of cup to be fixed in the installing port that detection platform is offered.
8. according to the intimate contact ultrasonic coupling adaptive device detected for mammary gland optoacoustic/thermal acoustic imaging according to claim 1, it is characterized in that: the opening of described detection cup arranges sealing ring, when breast to be measured is placed in detection cup, sealing ring is close to breast to be measured and is detected cup.
9. according to the detection method of the intimate contact ultrasonic coupling adaptive device for mammary gland optoacoustic/thermal acoustic imaging detection according to claim 6, it is characterized in that: comprise the steps: by coupling liquid liquid-jet device, ultrasonic coupling liquid to be sprayed between breast to be measured and detection cup, the gas between breast to be measured and detection cup is drawn again by barometric control unit, under the effect of negative pressure and ultrasonic coupling liquid, realize breast to be measured and detect the close contact of cup, finally by with the use of annular array checkout gear scan.
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| CN105816203B (en) * | 2016-02-29 | 2018-08-14 | 周茂英 | A kind of obstetrics' observing and treating instrument |
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| CN106264614A (en) * | 2016-07-23 | 2017-01-04 | 深圳市前海安测信息技术有限公司 | Health detection all-in-one for mammary gland examination |
| CN107260202B (en) * | 2017-07-05 | 2021-01-15 | 山东省肿瘤防治研究院 | Mammary gland imaging dragging device for improving mammary gland imaging effect |
| CN107713990A (en) * | 2017-10-31 | 2018-02-23 | 华南师范大学 | A kind of thermoacoustic, optoacoustic, ultrasonic three mode tumor of breast detection means and method |
| CN110179461A (en) * | 2019-06-24 | 2019-08-30 | 深圳市太赫兹科技有限公司 | A kind of multi-channel portable Microwave Scanning Brian Imaging device and method |
| CN112971715B (en) * | 2021-01-28 | 2023-02-03 | 华南师范大学 | Imaging device and method for thermo-acoustic, photo-acoustic and ultrasonic collinear excitation and reception |
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