CN204995443U - A optoacoustic integration probe for breast cancer detection - Google Patents
A optoacoustic integration probe for breast cancer detection Download PDFInfo
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- CN204995443U CN204995443U CN201520752690.6U CN201520752690U CN204995443U CN 204995443 U CN204995443 U CN 204995443U CN 201520752690 U CN201520752690 U CN 201520752690U CN 204995443 U CN204995443 U CN 204995443U
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- 239000000523 sample Substances 0.000 title claims abstract description 36
- 238000001514 detection method Methods 0.000 title claims abstract description 12
- 206010006187 Breast cancer Diseases 0.000 title claims abstract description 10
- 208000026310 Breast neoplasm Diseases 0.000 title claims abstract description 10
- 230000010354 integration Effects 0.000 title abstract 2
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- 230000008878 coupling Effects 0.000 claims abstract description 19
- 238000010168 coupling process Methods 0.000 claims abstract description 19
- 238000005859 coupling reaction Methods 0.000 claims abstract description 19
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- Ultra Sonic Daignosis Equipment (AREA)
- Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
Abstract
The utility model discloses an optoacoustic integration probe for breast cancer detection, it relates to optoacoustic tomographic image field, one end and many first array receipt type ultrasonic transducer of the positive and negative electrode lead cable of ultrasonic transducer are connected, the other end of the positive and negative electrode lead cable of ultrasonic transducer assembles into a branch ofly with the one end of one fen multi beam optic fibre in the department of central authorities of probe, and set up in the fixed protection tube of optical fiber cable, optical fiber cable is fixed, and the afterbody at the probe shell is installed to the protection tube, the front end of probe shell is provided with the probe light inlet window, both sides equal spraying except that the laser projecting window of probe light inlet window has extinction black paint layer. It combines be in the same place through radiating light source, ultrasonic coupling and array supersound receiving transducer, not only can realize the many first optoacoustics to the photoacoustic imaging of the large tracts of land that biological tissue is quick, convenient, can also satisfy the many first array optoacoustics of broadband of printing opacity and entrant sound simultaneously, and solved the low decay output of laser and the supersound is highly sensitive and the input of high bandwidth.
Description
technical field:
This utility model relates to a kind of optoacoustic integrated probe for breast cancer detection, belongs to photoacoustic tomography technical field.
background technology:
When with certain absorber of photoirradiation, absorber absorbing light energy and produce temperature rise, gradient of temperature causes the volume dilational of absorber, and produce ultrasound wave, this phenomenon is called optoacoustic effect.At the seventies, optoacoustic effect is used to spectral investigation, defines optoacoustic spectroscopy.Be introduced into imaging in biological tissues field in the eighties optoacoustic effect, define the photoacoustic tomography technology of biological tissue.Photoacoustic imaging technology combines the advantage organized pure optical imagery He organize pure ultra sonic imaging, due to tissue to ultrasonic decay and scattering much smaller than tissue to the decay of light and scattering, detect ultrasound wave with broad band ultrasonic probe to replace detecting scattered photon in optical imagery, again in conjunction with the high-contrast of tumor tissues and normal structure, therefore photoacoustic imaging can produce the high-resolution tissue image of high contrast.The method has a lot of advantages relative to other formation method: compared with NMR (Nuclear Magnetic Resonance)-imaging, and its imaging cost is much lower; It does not have radiation compared with X-ray method; Its imaging depth will be firmly got many compared with OCT, reaches about 10mm to 20mm; By the laser irradiation biological tissue of specific wavelength, photoacoustic method can also realize function imaging.
Although photoacoustic imaging technology has lot of advantages, but also there are some technical difficulties and hinder its application in Clinical detection and diagnosis, these difficulties mainly comprise the following aspects: one, the restriction of data acquisition time: photoacoustic imaging technology mainly adopts single ultrasonic transducer to adopt the mode of rotation sweep or point by point scanning to gather photoacoustic signal in the world at present, its imaging has higher picture contrast and resolution, but this several mode data acquisition time is long, dozens of minutes is generally needed not arrive several hours not etc., two, the bandwidth of the probe of photoacoustic imaging, sensitivity, the isoparametric restriction of resolution, because the complex array do not designed for photoacoustic imaging specially is at present popped one's head in, the complex array probe of present use is also the multiple linear array probe for B ultrasonic imaging directly bought, when designing with respect to the intensity of ultrasound emission, so present ultrasonic probe all adopts piezoceramic material, and acoustic design designs as transceiver transducer, cause the bandwidth of probe narrower, therefore resolution is not high, and photoacoustic imaging receives only ultrasonic and does not need transmitting ultrasonic, so the PVDF material of high bandwidth or composite piezoelectric ceramics can be adopted to pop one's head according to the requirement design complex array of receiving transducer, three, imaging device is complicated, operation inconvenience, current photoacoustic imaging system is separated LASER Light Source, probe substantially with ultrasonic coupling agent, adopt laser vertical radiation, pop one's head at side reception photoacoustic signal, adopt water as ultrasonic coupling agent, the pattern of this separation was both not suitable for clinical manipulation, also made the position of detection be restricted.
summary of the invention:
For the problems referred to above, the technical problems to be solved in the utility model is to provide a kind of optoacoustic integrated probe for breast cancer detection.
A kind of optoacoustic integrated probe for breast cancer detection of the present utility model, it comprises one point of multiple beams of optical fiber, optical total-reflection mirror, photon-phonon coupling material layer, complex array receiving type ultrasonic transducer, ultrasonic transducer positive and negative electrode leader cable, protecting tube fixed by fiber optic cables, probing shell, probe light inlet window, the pitch-dark layer of extinction, one point of multiple beams of optical fiber interval be fixed on the both sides holddown groove of probing shell inside, the optical fiber head of one point of multiple beams of optical fiber is vertically set on the minute surface of optical total-reflection mirror, the inside of probing shell is provided with photon-phonon coupling material layer, complex array receiving type ultrasonic transducer is arranged on the inside axis of probing shell, one end of ultrasonic transducer positive and negative electrode leader cable is connected with complex array receiving type ultrasonic transducer, the other end of ultrasonic transducer positive and negative electrode leader cable and one end of one point of multiple beams of optical fiber pool a branch of in the centre of popping one's head in, and be arranged on fiber optic cables and fix in protecting tube, the afterbody that protecting tube is arranged on probing shell fixed by fiber optic cables, the front end of probing shell is provided with probe light inlet window, the both sides of probe light inlet window are all coated with the pitch-dark layer of extinction except laser projections window.
As preferably, the other materials that described photon-phonon coupling material layer adopts acryl solid material or has a printing opacity entrant sound is made, the feature of acryl solid material is that the acoustic impedance of its acoustic impedance and human body is close, acoustic impedance coupling can be realized, and this material acoustic attenuation coefficient is little, ultrasonic low decay input can be realized.
As preferably, described complex array receiving type ultrasonic transducer is by the first matching layer, second matching layer, piezoelectric element, complex array receiving type ultrasonic transducer backing material forms, wherein piezoelectric element is the piezoelectric that under thickness vibration mode, electromechanical conversion coefficient is high, the acoustic impedance of acoustic impedance as far as possible with piezoelectric element used of complex array receiving type ultrasonic transducer backing material is close, acoustic attenuation coefficient is more than or equal to 80dB/cm, according to KLM modelling matching layer, it can be multiple structure, be generally two-layer, acoustic impedance is between piezoelectric element and acryl material, other processing technique is identical with general B ultrasonic array probe.
As preferably, described ultrasonic transducer positive and negative electrode leader cable is made up of piezoelectric element positive wire and piezoelectric element negative wire.
The beneficial effects of the utility model: it is by combining radiating light source, ultrasonic coupling and array ultrasonic receiving transducer, the polynary optoacoustic to biological tissue's large-area photoacoustic imaging fast, easily can not only be realized, can also meet the broadband complex array optoacoustic of printing opacity and entrant sound, the low decay solving laser exports the input with ultrasonic highly sensitive and high bandwidth simultaneously.
accompanying drawing illustrates:
For ease of illustrating, this utility model is described in detail by following concrete enforcement and accompanying drawing.
Fig. 1 is structural representation of the present utility model;
Fig. 2 is cross-sectional structure schematic diagram of the present utility model;
Fig. 3 is vertical section structure schematic diagram of the present utility model;
Fig. 4 is the distribution schematic diagram of light inlet window of popping one's head in this utility model.
1-mono-point of multiple beams of optical fiber; 2-optical total-reflection mirror; 3-photon-phonon coupling material layer; 4-complex array receiving type ultrasonic transducer; 4-1-first matching layer; 4-2-second matching layer; 4-3-piezoelectric element; 4-4-complex array receiving type ultrasonic transducer backing material; 5-ultrasonic transducer positive and negative electrode leader cable; 5-1-piezoelectric element positive wire; 5-2-piezoelectric element negative wire; Protecting tube fixed by 6-fiber optic cables; 7-probing shell; 8-pops one's head in light inlet window; The pitch-dark layer of 9-extinction.
detailed description of the invention:
As Figure 1-Figure 4, this detailed description of the invention is by the following technical solutions: it comprises one point of multiple beams of optical fiber 1, optical total-reflection mirror 2, photon-phonon coupling material layer 3, complex array receiving type ultrasonic transducer 4, ultrasonic transducer positive and negative electrode leader cable 5, protecting tube 6 fixed by fiber optic cables, probing shell 7, probe light inlet window 8, the pitch-dark layer 9 of extinction, on the both sides holddown groove being fixed on probing shell 7 inside at one point of multiple beams of optical fiber 1 interval, the optical fiber head of one point of multiple beams of optical fiber 1 is vertically set on the minute surface of optical total-reflection mirror 2, the inside note of probing shell 7 is provided with photon-phonon coupling material layer 3, complex array receiving type ultrasonic transducer 4 is arranged on the inside axis of probing shell 7, one end of ultrasonic transducer positive and negative electrode leader cable 5 is connected with complex array receiving type ultrasonic transducer 4, the other end of ultrasonic transducer positive and negative electrode leader cable 5 and one end of one point of multiple beams of optical fiber 1 pool a branch of in the centre of popping one's head in, and be arranged on fiber optic cables and fix in protecting tube 6, the afterbody that protecting tube 6 is arranged on probing shell 7 fixed by fiber optic cables, the front end of probing shell 7 is provided with probe light inlet window 8, the both sides of probe light inlet window 8 are all coated with the pitch-dark layer 9 of extinction except laser projections window.
Wherein, the other materials that described photon-phonon coupling material layer 3 adopts acryl solid material or has a printing opacity entrant sound is made, the feature of acryl solid material is that the acoustic impedance of its acoustic impedance and human body is close, acoustic impedance coupling can be realized, and this material acoustic attenuation coefficient is little, ultrasonic low decay input can be realized, described complex array receiving type ultrasonic transducer 4 is by the first matching layer 4-1, second matching layer 4-2, piezoelectric element 4-3, complex array receiving type ultrasonic transducer backing material 4-4 forms, wherein piezoelectric element 4-3 is the piezoelectric that under thickness vibration mode, electromechanical conversion coefficient is high, the acoustic impedance of acoustic impedance as far as possible with piezoelectric element used of complex array receiving type ultrasonic transducer backing material 4-4 is close, acoustic attenuation coefficient is more than or equal to 80dB/cm, according to KLM modelling matching layer, it can be multiple structure, be generally two-layer, acoustic impedance is between piezoelectric element and acryl material, other processing technique is identical with general B ultrasonic array probe, described ultrasonic transducer positive and negative electrode leader cable 5 is made up of piezoelectric element positive wire 5-1 and piezoelectric element negative wire 5-2.
The photo-acoustic excitation source of this detailed description of the invention adopts multifiber transmission laser, optical fiber is equally spaced arranged vertically in probe both sides, by optical total-reflection mirror 2 by the vertical lower of laser beam reflection to complex array receiving type ultrasonic transducer 4, the distance between optical fiber equals the size of the hot spot of the vertical lower being incident on complex array receiving type ultrasonic transducer 4.
The manufacture method of this detailed description of the invention: a, making receiving type wide frequency band high sensitivity complex array ultrasonic transducer; B, be fixed on the both sides holddown groove of mould by equally spaced for one point of multiple beams of optical fiber 1, central axis complex array receiving type ultrasonic transducer 4 being placed in mould fixes; The mode of c, employing priming by vacuum, will be melted into liquid acryl material and inject mold slots; D, etc. natural cooling after 12 hours, put into freezing 4 hours of the freezer of subzero 20 degrees Celsius, take out and move back mould; F, light inlet window is sticked adhesive tape after, spray pitch-dark at coupling material outer surface, the width of optical transmission window and spot size are suitable, are positioned at the center of probe coupling surface; E, probe general assembly complete; Multifiber is adopted to form large-area uniform light field as radiating light source in this manufacture method, the low decay adopting the acryl material of printing opacity, entrant sound to realize laser as ultrasonic coupling material exports and ultrasonic low decay input, adopts the complex array receiving type transducer of the piezoelectrics such as the PVDF high polymer that electromechanical coupling factor is high, passband characteristic is good to carry out the acoustic-electric conversion of high sensitivity, wide bandwidth.
This detailed description of the invention is by combining radiating light source, ultrasonic coupling and array ultrasonic receiving transducer, the polynary optoacoustic to biological tissue's large-area photoacoustic imaging fast, easily can not only be realized, can also meet the broadband complex array optoacoustic of printing opacity and entrant sound, the low decay solving laser exports the input with ultrasonic highly sensitive and high bandwidth simultaneously.
More than show and describe ultimate principle of the present utility model and principal character and advantage of the present utility model.The technical staff of the industry should understand; this utility model is not restricted to the described embodiments; what describe in above-described embodiment and description just illustrates principle of the present utility model; under the prerequisite not departing from this utility model spirit and scope; this utility model also has various changes and modifications, and these changes and improvements all fall within the scope of claimed this utility model.The claimed scope of this utility model is defined by appending claims and equivalent thereof.
Claims (4)
1. the optoacoustic integrated probe for breast cancer detection, it is characterized in that: it comprises one point of multiple beams of optical fiber (1), optical total-reflection mirror (2), photon-phonon coupling material layer (3), complex array receiving type ultrasonic transducer (4), ultrasonic transducer positive and negative electrode leader cable (5), protecting tube (6) fixed by fiber optic cables, probing shell (7), probe light inlet window (8), the pitch-dark layer of extinction (9), on the both sides holddown groove being fixed on probing shell (7) inside at one point of multiple beams of optical fiber (1) interval, the optical fiber head of one point of multiple beams of optical fiber (1) is vertically set on the minute surface of optical total-reflection mirror (2), the inside of probing shell (7) is provided with photon-phonon coupling material layer (3), complex array receiving type ultrasonic transducer (4) is arranged on the inside axis of probing shell (7), one end of ultrasonic transducer positive and negative electrode leader cable (5) is connected with complex array receiving type ultrasonic transducer (4), the other end of ultrasonic transducer positive and negative electrode leader cable (5) and one end of one point of multiple beams of optical fiber (1) pool a branch of in the centre of popping one's head in, and be arranged on fiber optic cables and fix in protecting tube (6), the afterbody that protecting tube (6) is arranged on probing shell (7) fixed by fiber optic cables, the front end of probing shell (7) is provided with probe light inlet window (8), the both sides of probe light inlet window (8) are all coated with the pitch-dark layer of extinction (9) except laser projections window.
2. a kind of optoacoustic integrated probe for breast cancer detection according to claim 1, is characterized in that: described photon-phonon coupling material layer (3) adopts acryl solid material.
3. a kind of optoacoustic integrated probe for breast cancer detection according to claim 1, is characterized in that: described complex array receiving type ultrasonic transducer (4) is made up of the first matching layer (4-1), the second matching layer (4-2), piezoelectric element (4-3), complex array receiving type ultrasonic transducer backing material (4-4).
4. a kind of optoacoustic integrated probe for breast cancer detection according to claim 1, is characterized in that: described ultrasonic transducer positive and negative electrode leader cable (5) is made up of piezoelectric element positive wire (5-1) and piezoelectric element negative wire (5-2).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520752690.6U CN204995443U (en) | 2015-09-25 | 2015-09-25 | A optoacoustic integration probe for breast cancer detection |
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| CN201520752690.6U CN204995443U (en) | 2015-09-25 | 2015-09-25 | A optoacoustic integration probe for breast cancer detection |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106691390A (en) * | 2017-01-22 | 2017-05-24 | 中国科学院深圳先进技术研究院 | Photoacoustic probe and photoacoustic imaging system |
| CN107174208A (en) * | 2017-05-24 | 2017-09-19 | 哈尔滨工业大学（威海） | A kind of photoacoustic imaging system and method suitable for peripheral vascular imaging |
| CN109490257A (en) * | 2018-12-28 | 2019-03-19 | 浙江五相智能科技有限公司 | Optical dissolved oxygen sensor and its manufacturing method with the compensation of automatic salinity |
| CN112716529A (en) * | 2019-10-28 | 2021-04-30 | 深圳市理邦精密仪器股份有限公司 | Eyeball detection equipment and ultrasonic probe thereof |
-
2015
- 2015-09-25 CN CN201520752690.6U patent/CN204995443U/en not_active Expired - Fee Related
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106691390A (en) * | 2017-01-22 | 2017-05-24 | 中国科学院深圳先进技术研究院 | Photoacoustic probe and photoacoustic imaging system |
| CN107174208A (en) * | 2017-05-24 | 2017-09-19 | 哈尔滨工业大学（威海） | A kind of photoacoustic imaging system and method suitable for peripheral vascular imaging |
| CN109490257A (en) * | 2018-12-28 | 2019-03-19 | 浙江五相智能科技有限公司 | Optical dissolved oxygen sensor and its manufacturing method with the compensation of automatic salinity |
| CN112716529A (en) * | 2019-10-28 | 2021-04-30 | 深圳市理邦精密仪器股份有限公司 | Eyeball detection equipment and ultrasonic probe thereof |
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Effective date of registration: 20160415 Address after: 412008 Wenhua Road, Hunan, Zhuzhou Patentee after: Hunan University of Technology Address before: 412007 No. 1, No. 51, Taishan Road, Tianyuan District, Hunan, Zhuzhou, 502 Patentee before: Yang Diwu |
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Granted publication date: 20160127 Termination date: 20160925 |