CN103536788A - 一种治疗毛发红糠疹的中药 - Google Patents
一种治疗毛发红糠疹的中药 Download PDFInfo
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Abstract
本发明涉及一种治疗毛发红糠疹的中药，由以下重量配比的药材制备而成：百部还魂12份、阿魏侧耳9份、阿尔太多榔菊14份、凹朴皮10份、暗鳞鳞毛蕨12份、盾叶薯蓣12份、安徽刺黄柏14份、阿育魏实15份、绣线菊15份、雾水葛10份、波缘楤木8份、芭茅10份、杧果12份、毛冬瓜14份、骆驼蓬12份、黄水枝12份。临床实验证明，本发明能够安全有效治疗毛发红糠疹。
Description
技术领域
本发明涉及一种中药，具体涉及一种治疗毛发红糠疹的中药。
背景技术
毛发红糠疹是一种慢性炎症性皮肤病。表现为毛囊性坚硬的尖形小丘疹，中央有黑色角栓，常密集成片，表面伴糠状鳞屑。该病病因不明，症状轻，病程迁延；成人时期发病者可能与维甲醇结合蛋白缺陷、低血浆维生素A或甲状腺功能障碍等有关(获得性型)，发病较快，可发展为红皮病。最显著组织病理特征是表皮角化过度及毛囊性角质栓，栓内有一根毛发。毛囊口附近有点状角化不全，颗粒层稍增厚，棘层不规则肥厚，可有基底细胞液化变化。
对于毛发红糠疹目前尚缺少公认安全有效的治疗药物。
本发明中药所涉及药材的研究现状如下：
百部还魂【来源】为三白草科植物裸蒴的全草或叶。【功能主治】敷跌打损伤，全株治乳疮；叶治蜈蚣咬伤。
阿魏侧耳【来源】为白蘑科真菌阿魏侧耳的子实体。采收和储藏：采收子实体，除去杂质，晒干。【功能主治】行气；消积；杀虫。主胃痛；食积；虫积。
阿尔太多榔菊【来源】菊科阿尔太多榔菊Doronicum altaicum Pallas[Cremanthodium calotum Diels]，以全草入药。【功能主治】祛痰止咳，宽胸利气。主治痰喘咳嗽。
凹朴皮【来源】为木兰科植物鹅掌楸和北美鹅掌楸的树皮。【功能主治】祛风除湿；散寒止咳。主风湿痹痛；风寒咳嗽。
暗鳞鳞毛蕨【来源】药材基源：为鳞鳞毛蕨科植物暗鳞鳞毛蕨的根茎。【功能主治】凉血止血；驱虫。主功能性子宫出血；蛔虫病。
盾叶薯蓣【来源】薯蓣科薯蓣属植物盾叶薯蓣Dioscorea zingiberensis C.H.Wright，以根状茎入药。春秋采挖，去净泥土，晒干。【功能主治】解毒消肿。用于痈疖早期未破溃，皮肤急性化脓性感染，软组织损伤，蜂螫虫咬。
安徽刺黄柏【来源】为小檗科植物安徽小檗的茎枝。【功能主治】清热燥湿；泻火解毒。主湿热痢疾；泄泻；黄疸；淋浊；带下；疮疡；咽喉肿痛；目赤肿痛
阿育魏实【来源】伞形科阿育魏实Trachyspermum ammi(L.)Sprague，以种子入药。【功能主治】祛风除湿，理气开胃，止痛。主治风湿疼痛，胃寒腹痛，消化不良，泌尿系结石。
绣线菊【来源】蔷薇科绣线菊属植物光叶绣线菊，以根及嫩叶入药。全年采根，洗净晒干；嫩叶夏季采。【功能主治】清热解毒。用于目赤肿痛，头痛，牙痛，肺热咳嗽；外用治创伤出血。
雾水葛【来源】荨麻科雾水葛属植物雾水葛Pouzolzia zeylanica(L.)Benn.，以全草入药。全年可采，洗净晒干或鲜用。【功能主治】清热利湿，解毒排脓。用于痢疾，肠炎，尿路感染；外用治疖肿，乳腺炎。
波缘楤木【来源】为五加科植物波缘楤木的根。夏、秋季采挖、除去杂质、洗净，鲜用或晒干。【功能主治】活血化瘀；通经止痛；祛风除湿。主跌打损伤；骨折；痞块；经闭；痛经；劳伤疼痛；风湿痛。
芭茅【来源】为禾本科植物芭茅的茎。夏、秋季采收，切段晒干。【功能主治】清热通淋；祛风和湿。主热淋；石淋；白浊；带下；风湿痹痛。
杧果【来源】漆树科杧果属植物杧果Mangifera indica L.，以果、果核、叶入药。全年采叶，夏秋采果，鲜用或晒干。【功能主治】果、果核：止咳，健胃，行气。用于咳嗽，食欲不振，睾丸炎，坏血病。叶：止痒。外用治湿疹瘙痒。
毛冬瓜【来源】猕猴桃科猕猴桃属植物毛花杨桃Actinidia eriantha Benth.，以根、根皮及叶入药。根全年可采，晒干；夏秋采叶，鲜用或晒干。【功能主治】抗癌，消肿解毒。根：用于胃癌、乳癌、食道癌、腹股沟淋巴结炎、疮疖、皮炎。根皮：外用治跌打损伤。叶：外用治乳腺炎。
骆驼蓬【来源】蒺藜科骆驼蓬属植物骆驼蓬Peganum harmala L.，以全草及种子入药。夏秋采全草，种子成熟时采，晒干或鲜用。【功能主治】宣肺止咳，祛风湿，解毒。子：咳嗽气喘。全草：外用治无名肿毒，风湿性关节炎。
黄水枝【来源】虎耳草科黄水枝属植物黄水枝Tiarella polyphylla D.Don，以全草入药。夏秋采集，晒干。【功能主治】清热解毒，活血祛瘀，消肿止痛。用于痈疖肿毒，跌打损伤，肝炎，咳嗽气喘。
发明内容
本发明旨在提供一种治疗毛发红糠疹的中药，通过选择合适的药材及其配比，达到安全有效治愈毛发红糠疹的目的。
为了达到上述目的，本发明采用以下技术方案：
一种治疗毛发红糠疹的中药，其特征在于，由以下重量配比的药材制备而成：百部还魂12份、阿魏侧耳9份、阿尔太多榔菊14份、凹朴皮10份、暗鳞鳞毛蕨12份、盾叶薯蓣12份、安徽刺黄柏14份、阿育魏实15份、绣线菊15份、雾水葛10份、波缘楤木8份、芭茅10份、杧果12份、毛冬瓜14份、骆驼蓬12份、黄水枝12份。
下面结合临床实验数据说明本发明的有益效果：
1、一般资料
发明人2009年11月-2011年12月间共收集115例毛发红糠疹的门诊患者，年龄19-45岁，病程7个月-3年。随机分为：治疗组85例，空白组30例。两组年龄、病情等资料无显著性差异，具有可比性。
2、试验方法
2.1治疗组口服本发明按照具体实施例1制得的胶囊，早晚各一次。疗程7天。
2.2空白组口服安慰剂胶囊，早晚各一次。疗程7天。
3、疗效标准与治疗结果
3.1疗效标准
痊愈：临床症状全部消失，试验室检查正常。好转：临床症状减轻，病情得到控制，实验室检查改善或正常。无效：临床症状无明显好转或加重。
3.2治疗统计结果见表1。
表1两组疗效比较
| 组别 | n | 痊愈 | 好转 | 无效 | 不良反应例 | 总有效率(％) |
| 治疗组 | 85 | 18(21.2％) | 42(49.4％) | 25(29.4％) | 0 | 70.6％ |
| 空白组 | 30 | 0 | 9(30％) | 21(70％) | 0 | 30％ |
可见，本发明制得的药物能够安全有效治毛发红糠疹。
具体实施方式
为了更好地理解和实施本发明，下面结合具体实施例进一步说明本发明。
具体实施例1
称取：百部还魂12克、阿魏侧耳9克、阿尔太多榔菊14克、凹朴皮10克、暗鳞鳞毛蕨12克、盾叶薯蓣12克、安徽刺黄柏14克、阿育魏实15克、绣线菊15克、雾水葛10克、波缘楤木8克、芭茅10克、杧果12克、毛冬瓜14克、骆驼蓬12克、黄水枝12克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，装入胶囊壳，即得符合正常成人1天用量的胶囊剂。
用于治疗毛发红糠疹。口服，每日分早晚两次服用。
具体实施例2
称取：百部还魂12克、阿魏侧耳9克、阿尔太多榔菊14克、凹朴皮10克、暗鳞鳞毛蕨12克、盾叶薯蓣12克、安徽刺黄柏14克、阿育魏实15克、绣线菊15克、雾水葛10克、波缘楤木8克、芭茅10克、杧果12克、毛冬瓜14克、骆驼蓬12克、黄水枝12克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，粉碎，即得符合正常成人1天用量的散剂。
用于治疗毛发红糠疹。口服，每日分早晚两次服用。
具体实施例3
称取：百部还魂12克、阿魏侧耳9克、阿尔太多榔菊14克、凹朴皮10克、暗鳞鳞毛蕨12克、盾叶薯蓣12克、安徽刺黄柏14克、阿育魏实15克、绣线菊15克、雾水葛10克、波缘楤木8克、芭茅10克、杧果12克、毛冬瓜14克、骆驼蓬12克、黄水枝12克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，再加入适量糊精和矫昧剂，按照本领域常规工艺制粒，包装，即可制得符合正常成人1天用量的颗粒剂。
用于治疗毛发红糠疹。口服，每日分早晚两次服用。
Claims (1)
1.一种治疗毛发红糠疹的中药，其特征在于，由以下重量配比的药材制备而成：百部还魂12份、阿魏侧耳9份、阿尔太多榔菊14份、凹朴皮10份、暗鳞鳞毛蕨12份、盾叶薯蓣12份、安徽刺黄柏14份、阿育魏实15份、绣线菊15份、雾水葛10份、波缘楤木8份、芭茅10份、杧果12份、毛冬瓜14份、骆驼蓬12份、黄水枝12份。
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104107253A (zh) * | 2014-06-30 | 2014-10-22 | 顾燕君 | 一种治疗毛发红糠疹的中药 |
| CN106389676A (zh) * | 2016-10-24 | 2017-02-15 | 张小林 | 一种治疗花斑糠疹的中药 |
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| 夏更德: "中药治疗毛发红糠疹", 《四川中医》, no. 2, 31 December 1991 (1991-12-31), pages 45 * |
| 张志礼著: "《跟名师学临床系列丛书.张志礼》", 30 June 2010, article "毛发红糠疹的中医药治疗体会", pages: 129-133 * |
| 杨瑾等: "毛发红糠疹中医治疗现状", 《北京中医药大学学报(中医临床版)》, vol. 13, no. 6, 30 November 2006 (2006-11-30), pages 45 - 46 * |
| 王萍主编: "《中医皮肤科主治医生748问》", 30 September 2010, article "中医如何治疗毛发红糠疹、当代医家如何对毛发红糠疹进行辨证分型治疗", pages: 528-529 - 531-532 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104107253A (zh) * | 2014-06-30 | 2014-10-22 | 顾燕君 | 一种治疗毛发红糠疹的中药 |
| CN104107253B (zh) * | 2014-06-30 | 2016-08-17 | 朱育盼 | 一种治疗毛发红糠疹的中药 |
| CN106389676A (zh) * | 2016-10-24 | 2017-02-15 | 张小林 | 一种治疗花斑糠疹的中药 |
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