CN103536690A - Traditional Chinese medicine oral liquid for reducing blood pressure - Google Patents
Traditional Chinese medicine oral liquid for reducing blood pressure Download PDFInfo
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Abstract
The invention discloses traditional Chinese medicine oral liquid for reducing the blood pressure, which is prepared from the following raw materials in parts by weight: 20-25 parts of radix astragali, 15-20 parts of fructus corni, 15-20 parts of semen plantaginis, 10-15 parts of fructus gardeniae, 10-15 parts of folium ginkgo, 10-15 parts of fructus schisandrae chinensis, 10-15 parts of fructus rubi, 10-15 parts of rhizoma atractylodis macrocephalae, 10-15 parts of fructus crataegi, 5-10 parts of radix codonopsis, 5-10 parts of flos sophorae, 5-10 parts of herba cistanche, 5-10 parts of radix angelicae pubescentis and 5-10 parts of angelica sinensis. The traditional Chinese medicine oral liquid disclosed by the invention is mainly used for calming the liver and suppressing yang and removing stasis and activating blood while taking care of the heart, liver, spleen and kidney and strengthening the spleen and clearing damp, and clinically realizes a perfect curative effect on the hypertensives.
Description
Technical field
The present invention relates to a kind of Chinese patent medicine, relate in particular to a kind of Chinese medicine oral liquid of blood pressure lowering.
Background technology
Hypertension is a kind of global common chronic disease, is also the topmost risk factor of cardiovascular and cerebrovascular disease, and apoplexy, myocardial infarction, heart failure and chronic kidney disease are its major complications, is the principal disease of harm humans health.Hypertension rate raises with age growth; Women's prevalence before climacteric, a little less than male, but raises rapidly after climacteric, even higher than male; High latitude cold district prevalence is higher than the warm area of low latitudes, and high altitude localities is higher than low altitude area; Relevant with dietary habit, salt and saturated fat are taken in higher, and mean blood pressure level and prevalence are also higher.Population of China hypertension is popular two relatively outstanding features: from south to the north, Prevalence of Hypertension is and increases progressively trend.The blood pressure level that reduces hyperpietic, can obviously reduce apoplexy and the events of heart attack, significantly improves patient's life quality, effectively reduces disease burden.
The antihypertensive Western medicine kind of current clinical use is more, but generally needs multi-medicament drug combination just can reach good blood pressure lowering effect, and still has some patients to conventional depressor unsatisfactory curative effect, or can not apply because of its side effect.And also have on the market the Chinese Traditional Medicines of a lot of blood pressure lowerings, but curative effect is unsatisfactory, can only when treatment, play the effect of auxiliary western medicine.
Summary of the invention
The object of the invention is to for above-mentioned technical problem, a kind of Chinese medicine oral liquid of evident in efficacy, blood pressure lowering that single drug is effective is provided.
For achieving the above object, the technical solution adopted in the present invention is: a kind of Chinese medicine oral liquid of blood pressure lowering, by the crude drug of following weight portion, made: Radix Astragali 20-25 part, Fructus Corni 15-20 part, Semen Plantaginis 15-20 part, Fructus Gardeniae 10-15 part, Folium Ginkgo 10-15 part, Fructus Schisandrae Chinensis 10-15 part, Fructus Rubi 10-15 part, Rhizoma Atractylodis Macrocephalae 10-15 part, Fructus Crataegi 10-15 part, Radix Codonopsis 5-10 part, Flos Sophorae 5-10 part, Herba Cistanches 5-10 part, Radix Angelicae Pubescentis 5-10 part, Radix Angelicae Sinensis 5-10 part.
Preferably: 23 parts of the Radixs Astragali, 17 parts of Fructus Corni, 17 parts of Semen Plantaginiss, 12 parts of Fructus Gardeniaes, 12 parts of Folium Ginkgos, 12 parts of Fructus Schisandrae Chinensis, 12 parts of Fructus Rubies, 12 parts of the Rhizoma Atractylodis Macrocephalaes, 12 parts of Fructus Crataegis, 7 parts of Radix Codonopsis, 7 parts, Flos Sophorae, 7 parts of Herba Cistanches, 7 parts of Radix Angelicae Pubescentiss, 7 parts of Radix Angelicae Sinensis.
The Chinese medicine oral liquid of blood pressure lowering of the present invention is made by following methods:
(1) take by weight each crude drug and mix, add the distilled water immersion of 10 times of weight after 5 hours, decoct twice, decoct for the first time 30 minutes, decoct for the second time 25 minutes;
(2) collecting decoction, filters, and is evaporated to every milliliter of decocting liquid and is equivalent to 1 gram of crude drug;
(3) in decocting liquid, add appropriate xylitol, sterilizing, packing, obtain oral liquid of the present invention.
The meridian distribution of property and flavor of above-mentioned medical material is as follows:
The Radix Astragali: sweet, temperature.Return lung, spleen channel.Can benefiting QI for strengthening the superficies, admittedly de-, the holder skin ulcer granulation promoting of arresting sweating, inducing diuresis to remove edema.Be used for the treatment of the deficiency of vital energy weak, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, carbuncle is difficult bursts, and burst and do not hold back for a long time, blood deficiency and yellow complexion, interior-heat is quenched one's thirst, chronic nephritis, albuminuria, diabetes etc.
Fructus Corni: sour, puckery, tepor.Return liver, kidney channel.Can liver and kidney tonifying, restrain astringent or styptic treatment for spontaneous sweating, controlling nocturnal emission with astringent drugs reducing urination, leukorrhagia stopping only collapses, hidroschesis, also has in addition promoting the production of body fluid to quench thirst.For soreness of waist and knee joint, dizziness and tinnitus, forgetful emission and spermatorrhea, enuresis frequent micturition, bleeding not during menses, menoxenia, profuse sweating collapse, interior-heat is quenched one's thirst.
Semen Plantaginis: sweet; Light; Cold nature.Return lung meridian; Liver Channel; Kidney channel; Urinary bladder channel.Clearing away heat and promoting diuresis; Eliminating dampness by diuresis antidiarrheal; Improving eyesight; Eliminate the phlegm.Cure mainly: main dysuria; Stranguria with turbid discharge leukorrhagia; Edema distension; Heat-damp in summer dysentery; Conjunctival congestion is hidden from view; Expectorant heat syndrome cough is breathed heavily.
Fructus Gardeniae: bitter, cold, nontoxic.GUIXIN warp; Liver Channel; Lung meridian; Stomach warp; Tri-jiao channel.Can pathogenic fire purging relieving restlessness; Clearing away heat-damp and promoting diuresis; Removing pathogenic heat from blood and toxic substance from the body.
Folium Ginkgo: mildly bitter flavor, property is flat.There is the beneficial heart, promoting blood circulation and stopping pain, astringe the lung relieving asthma, the effect of removing dampness antidiarrheal.
Fructus Schisandrae Chinensis: temperature; Sour, sweet; Return lung, the heart, kidney channel.Can restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.For chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous perspiration, night sweat, Tianjin wound is thirsty, the deficient pulse of losing heart, interior-heat is quenched one's thirst, palpitation and insomnia.
Fructus Rubi: sweet acid, flat.Return liver; Kidney channel.Can the liver and the kidney tonifying, controlling nocturnal emission with astringent drugs reducing urination, improving eyesight.
The Rhizoma Atractylodis Macrocephalae: bitter, sweet, temperature.Return spleen, stomach warp.Air making-up and spleen enlivening, dampness diuretic, hidroschesis, antiabortive.
Fructus Crataegi: appetite-stimulating indigestion-relieving, change stagnant removing food stagnancy, promoting blood circulation to remove blood stasis, the circulation of qi promoting of reducing phlegm.For carnivorous stagnant long-pending, lump in the abdomen, abdominal distention feeling of fullness, stasis blocking stomachache, phlegm retention, have loose bowels, discharging fresh blood stool etc.
Radix Codonopsis: property is flat, sweet in the mouth, micro-acid.Return spleen, lung meridian.Middle QI invigorating, spleen invigorating lung benefiting.For deficiency of the spleen and lung, the cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency cough, interior-heat is quenched one's thirst.
Flos Sophorae: bitter in the mouth; Cold nature.Return liver; Lung; The heart; Large intestine channel.Cooling blood for hemostasis; Liver heat removing and eyesight improving.Main discharging fresh blood stool; Hemorrhoid hematochezia; Dysentery; Hematuria; Stranguria with blood; Metrorrhagia; Spit blood; Epistaxis; Liver-heat headache; Conjunctival congestion and swelling pain; Carbuncle skin infection.Be used for having blood in stool, hemorrhoidal bleeding, dysentery, metrorrhagia, spits blood, epistaxis, liver-heat conjunctival congestion, has a headache dizzy.
Herba Cistanches: sweet in the mouth, salty, warm in nature.Energy kidney-replenishing, benefiting essence-blood, loosening bowel to relieve constipation.
Radix Angelicae Pubescentis: pungent, bitter, tepor.Return liver, kidney, urinary bladder channel.For wind prevailing over dampness; Dispersing cold for relieving pain.For anemofrigid-damp arthralgia; Lumbocrural pain; Few cloudy volt wind headache, headache toothache.
Radix Angelicae Sinensis: sweet in the mouth; Pungent; Bitter; Warm in nature.Return liver; The heart; Spleen channel.Enrich blood; Invigorate blood circulation; Menstruction regulating and pain relieving; Moisturize laxation.
The Chinese medicine oral liquid of a kind of blood pressure lowering provided by the present invention, take suppressing the hyperactive liver and subsiding YANG, promoting blood circulation by removing blood stasis as main, takes into account the heart, liver,spleen,kidney, and invigorating the spleen to clear away damp pathogen, has good curative effect to hyperpietic clinically.
Embodiment
Following examples are used for illustrating the present invention, but are not used for limiting the scope of the invention.Do not deviating from the present invention spirit and essential in the situation that, the modification that the inventive method, step or condition are done or replacement, all belong to scope of the present invention.
Embodiment 1
Take by weight following crude drug: 20 parts of the Radixs Astragali, 15 parts of Fructus Corni, 15 parts of Semen Plantaginiss, 10 parts of Fructus Gardeniaes, 10 parts of Folium Ginkgos, 10 parts of Fructus Schisandrae Chinensis, 10 parts of Fructus Rubies, 10 parts of the Rhizoma Atractylodis Macrocephalaes, 10 parts of Fructus Crataegis, 5 parts of Radix Codonopsis, 5 parts, Flos Sophorae, 5 parts of Herba Cistanches, 5 parts of Radix Angelicae Pubescentiss, 5 parts of Radix Angelicae Sinensis.
Make by the following method Chinese medicine oral liquid:
(1) take by weight each crude drug and mix, add the distilled water immersion of 10 times of weight after 5 hours, decoct twice, decoct for the first time 30 minutes, decoct for the second time 25 minutes;
(2) collecting decoction, filters, and is evaporated to every milliliter of decocting liquid and is equivalent to 1 gram of crude drug;
(3) in decocting liquid, add appropriate xylitol, sterilizing, packing, obtain oral liquid of the present invention.
Embodiment 2
Take by weight following crude drug: 25 parts of the Radixs Astragali, 20 parts of Fructus Corni, 20 parts of Semen Plantaginiss, 15 parts of Fructus Gardeniaes, 15 parts of Folium Ginkgos, 15 parts of Fructus Schisandrae Chinensis, 15 parts of Fructus Rubies, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts of Fructus Crataegis, 10 parts of Radix Codonopsis, 10 parts, Flos Sophorae, 10 parts of Herba Cistanches, 10 parts of Radix Angelicae Pubescentiss, 10 parts of Radix Angelicae Sinensis.
(1) take by weight each crude drug and mix, add the distilled water immersion of 10 times of weight after 5 hours, decoct twice, decoct for the first time 30 minutes, decoct for the second time 25 minutes;
(2) collecting decoction, filters, and is evaporated to every milliliter of decocting liquid and is equivalent to 1 gram of crude drug;
(3) in decocting liquid, add appropriate xylitol, sterilizing, packing, obtain oral liquid of the present invention.
Embodiment 3
Take by weight following crude drug: 23 parts of the Radixs Astragali, 17 parts of Fructus Corni, 17 parts of Semen Plantaginiss, 12 parts of Fructus Gardeniaes, 12 parts of Folium Ginkgos, 12 parts of Fructus Schisandrae Chinensis, 12 parts of Fructus Rubies, 12 parts of the Rhizoma Atractylodis Macrocephalaes, 12 parts of Fructus Crataegis, 7 parts of Radix Codonopsis, 7 parts, Flos Sophorae, 7 parts of Herba Cistanches, 7 parts of Radix Angelicae Pubescentiss, 7 parts of Radix Angelicae Sinensis.
(1) take by weight each crude drug and mix, add the distilled water immersion of 10 times of weight after 5 hours, decoct twice, decoct for the first time 30 minutes, decoct for the second time 25 minutes;
(2) collecting decoction, filters, and is evaporated to every milliliter of decocting liquid and is equivalent to 1 gram of crude drug;
(3) in decocting liquid, add appropriate xylitol, sterilizing, packing, obtain oral liquid of the present invention.
Clinical treatment:
Hyperpietic's 200 examples, male 110 examples wherein, female's 90 examples, age 55-75 year, are divided into 1 group of embodiment, 2 groups of embodiment, 3 groups of embodiment, matched group by medical order, every group of each 50 examples at random.
TCM syndrome diagnostic criteria is with reference to Ministry of Public Health < < new Chinese medicine Hypertension guideline of clinical investigations > >, the < < hypertension prevention and control guide > > that Evaluation of Diagnostic Criteria of Hypertension is formulated with reference to World Health Organization (WHO) and Chinese hypertension alliance.
1 group of embodiment every day the oral embodiment of the present invention 1 oral liquid, every day 2 times, each 30ml; 2 groups of embodiment every day the oral embodiment of the present invention 2 oral liquid, every day 2 times, each 30ml; 3 groups of embodiment every day the oral embodiment of the present invention 3 oral liquid, every day 2 times, each 30ml; Matched group is taken commercially available chrysanthemum publicly price-reduction tabletting, every day 2 times, each 10.
Criterion of therapeutical effect: the efficacy of antihypertensive treatment standard of formulating in the guideline of clinical investigations > > with reference to Ministry of Public Health < < new Chinese medicine Hypertension.Effective: (1) diastole pressure drop is low≤1.3kPa, and reach normal range; (2) though diastolic pressure does not drop to normally, Xia Jiang≤2.7kPa, must possess wherein 1.Effective: (1) diastolic pressure decline <1.3kPa, but reached normal range; (2) diastolic pressure is treated front decline 1.3-2.5kPa, but does not reach normal range; (3) systolic pressure is treated front decline≤4.0kPa, must possess wherein 1.Invalid: not reach above-mentioned standard.
Therapeutic effect is as table 1:
Table 1
As can be seen from Table 1, in clinical treatment, 3 embodiment of the present invention are to hyperpietic's curative effect all higher than commercially available depressor chrysanthemum publicly price-reduction tabletting, and wherein the oral liquid antihypertensive effect of embodiment 3 gained is best.
Claims (3)
1. a Chinese medicine oral liquid for blood pressure lowering, is characterized in that, by the crude drug of following weight portion, is made: Radix Astragali 20-25 part, Fructus Corni 15-20 part, Semen Plantaginis 15-20 part, Fructus Gardeniae 10-15 part, Folium Ginkgo 10-15 part, Fructus Schisandrae Chinensis 10-15 part, Fructus Rubi 10-15 part, Rhizoma Atractylodis Macrocephalae 10-15 part, Fructus Crataegi 10-15 part, Radix Codonopsis 5-10 part, Flos Sophorae 5-10 part, Herba Cistanches 5-10 part, Radix Angelicae Pubescentis 5-10 part, Radix Angelicae Sinensis 5-10 part.
2. according to the Chinese medicine oral liquid of a kind of blood pressure lowering claimed in claim 1, it is characterized in that, by the crude drug of following weight portion, made: 23 parts of the Radixs Astragali, 17 parts of Fructus Corni, 17 parts of Semen Plantaginiss, 12 parts of Fructus Gardeniaes, 12 parts of Folium Ginkgos, 12 parts of Fructus Schisandrae Chinensis, 12 parts of Fructus Rubies, 12 parts of the Rhizoma Atractylodis Macrocephalaes, 12 parts of Fructus Crataegis, 7 parts of Radix Codonopsis, 7 parts, Flos Sophorae, 7 parts of Herba Cistanches, 7 parts of Radix Angelicae Pubescentiss, 7 parts of Radix Angelicae Sinensis.
3. according to the preparation method of the Chinese medicine oral liquid of a kind of blood pressure lowering described in claim 1 or 2, it is characterized in that, make according to the following steps:
(1) take by weight each crude drug and mix, add the distilled water immersion of 10 times of weight after 5 hours, decoct twice, decoct for the first time 30 minutes, decoct for the second time 25 minutes;
(2) collecting decoction, filters, and is evaporated to every milliliter of decocting liquid and is equivalent to 1 gram of crude drug;
(3) in decocting liquid, add appropriate xylitol, sterilizing, packing, obtain oral liquid of the present invention.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310463394.XA CN103536690B (en) | 2013-10-08 | 2013-10-08 | Traditional Chinese medicine oral liquid for reducing blood pressure |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310463394.XA CN103536690B (en) | 2013-10-08 | 2013-10-08 | Traditional Chinese medicine oral liquid for reducing blood pressure |
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| Publication Number | Publication Date |
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Cited By (2)
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| CN104147381A (en) * | 2014-08-25 | 2014-11-19 | 王深涧 | Traditional Chinese medicine composition for treating hypertension and preparation method thereof |
| CN107158130A (en) * | 2017-05-13 | 2017-09-15 | 蚌埠永济堂医药有限公司 | A kind of Chinese patent drug for treating hypertension |
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Cited By (4)
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| CN104147381A (en) * | 2014-08-25 | 2014-11-19 | 王深涧 | Traditional Chinese medicine composition for treating hypertension and preparation method thereof |
| CN104147381B (en) * | 2014-08-25 | 2015-04-22 | 曹荣芳 | Traditional Chinese medicine composition for treating hypertension and preparation method thereof |
| CN107158130A (en) * | 2017-05-13 | 2017-09-15 | 蚌埠永济堂医药有限公司 | A kind of Chinese patent drug for treating hypertension |
| CN107158130B (en) * | 2017-05-13 | 2020-09-29 | 蚌埠永济堂医药有限公司 | Chinese patent medicine for treating hypertension |
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Effective date of registration: 20200727 Address after: 063000 No.136 Park Road, Fengrun District, Tangshan City, Hebei Province Patentee after: JINGZHONGSHAN SINOPHARM (TANGSHAN) Co.,Ltd. Address before: 546199 the Guangxi Zhuang Autonomous Region road Laibin City District No. 315 Patentee before: Qin Shu Ren |