CN103518749A - Biological mildew inhibitor and application thereof - Google Patents
Biological mildew inhibitor and application thereof Download PDFInfo
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- CN103518749A CN103518749A CN201310475600.9A CN201310475600A CN103518749A CN 103518749 A CN103518749 A CN 103518749A CN 201310475600 A CN201310475600 A CN 201310475600A CN 103518749 A CN103518749 A CN 103518749A
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- biological
- mould inhibitor
- natamycin
- mildew inhibitor
- inhibitor
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Abstract
A biological mildew inhibitor and application thereof relates to a mildew inhibitor and application thereof, and the biological mildew inhibitor mainly aims at solving the problems that conventional mildew inhibitors possess corrosion effect and cause color change and residual stains. The biological mildew inhibitor is composed of 0.2-2 g/L of natamycin, 0.2-10 g/L of cyclodextrin, 100-800 g/L of a hydrophilic solvent and the balance purified water. The biological mildew inhibitor is applicable to mildew resistance for clothes, furniture and wall spaces. Because of the purely-biological mildew inhibitor natamycin applied in the biological mildew inhibitor provided by the invention, the biological mildew inhibitor has extremely good mould-inhibiting effect, has no corrosion effect when sprayed on clothes, furniture and the like, and does not cause phenomena such as color change, residual stain and the like. The biological mildew inhibitor is applicable to the field of mildew inhibitors.
Description
Technical field
The present invention relates to mould inhibitor and application thereof, relate in particular to the application in the mildew-resistant such as clothing and furniture, metope as mould inhibitor of biological preservative natamycin.
Background technology
At plum rain season because the wetness of air is large, clothing, furniture, metope etc. are easy to grow mould, thereby cause the damage of clothing, the phenomenons such as furniture surface, metope variable color decortication, existing mould inhibitor can have corrosiveness to clothing, furniture etc. because it contains chemical composition, even can cause the phenomenons such as variable color and residual seal stain.
Natamycin (Natamycin) is a kind of 20 hexa-atomic polyene macrolide antibiotics that produced by a kind of Natal streptomycete (Streptomyces natalensis) fermentation, effectively suppressing and kill mould and saccharomycete, is a kind of safety, low toxicity, efficient, the antifungal antibiotic of wide spectrum and natural biological preservative.Compare with other antimicrobial product, natamycin is extremely low to the toxicity of mammalian cell, can be widely used in by fungus-caused disease.In June nineteen eighty-two, U.S. FDA official approval natamycin can be used as food preservative.In March, 1997, China Ministry of Public Health official approval natamycin was as food preservative.
Summary of the invention
The object of the invention is has corrosiveness and causes variable color and the problem of residual seal stain in order to solve existing mould inhibitor, and a kind of biological mould inhibitor and application thereof are provided.
A kind of biological mould inhibitor of the present invention is comprised of the pure water of natamycin 0.2～2g/L, cyclodextrin 0.2～10g/L, hydrophilic solvent 100～800g/L and surplus.
The biological mould inhibitor of the present invention is used for clothing, furniture and metope as mould inhibitor.
Described biological mould inhibitor general guide using method is as follows:
Biological mould inhibitor is directly sprayed onto on clothing, furniture, metope, can plays and kill mould and prevent the effect that mould grows.
The present invention comprises following beneficial effect:
1, in the present invention, natamycin plays mildew-resistant; Cyclodextrin is cosolvent, plays the effect that improves natamycin solvability; Hydrophilic solvent mainly plays a part to be sprayed onto volatilization fast on clothing at mould inhibitor, also plays the effect that improves natamycin solvability;
2, biological mould inhibitor is comprised of the mould inhibitor natamycin of pure biology, has the effect of extraordinary mould fungus inhibition, and being sprayed onto clothing, furniture etc. does not have corrosiveness above, can not cause the phenomenons such as variable color and residual seal stain;
3, mould inhibitor of the present invention is mainly comprised of biological preservative, and effective kill fungi, for causing that mould that clothing goes mouldy etc. has good killing action.The biological mould inhibitor of the present invention is mainly used in the mildew-resistant on clothing surface, also can expand to the mildew-resistant on the surfaces such as furniture, house wall surface, and killing fungus rate reaches more than 99.9%.
Embodiment
Technical solution of the present invention is not limited to following cited embodiment, also comprises any combination between each embodiment.
Embodiment one: present embodiment biological bactericide is comprised of the pure water of nisin 0.2～5g/L, EDETATE SODIUM 1～15g/L, glycerine 50～100g/L, hydrophilic solvent 10～200g/L, edible organic acid 1～10g/L, essence 0.01～0.5g/L and surplus.
The beneficial effect of present embodiment:
1, in the present invention, natamycin plays mildew-resistant; Cyclodextrin is cosolvent, plays the effect that improves natamycin solvability; Hydrophilic solvent mainly plays a part to be sprayed onto volatilization fast on clothing at mould inhibitor, also plays the effect that improves natamycin solvability;
2, biological mould inhibitor is comprised of the mould inhibitor natamycin of pure biology, has the effect of extraordinary mould fungus inhibition, and being sprayed onto clothing, furniture etc. does not have corrosiveness above, can not draw the phenomenons such as variable color and residual seal stain;
3, mould inhibitor of the present invention is mainly comprised of biological preservative, and effective kill fungi, for causing that mould that clothing goes mouldy etc. has good killing action.The biological mould inhibitor of the present invention is mainly used in the mildew-resistant on clothing surface, also can expand to the mildew-resistant on the surfaces such as furniture, house wall surface, and killing fungus rate reaches more than 99.9%.
Embodiment two: present embodiment is different from embodiment one: described biological mould inhibitor is comprised of the pure water of natamycin 0.5～1.5g/L, cyclodextrin 0.2～10g/L, hydrophilic solvent 100～800g/L and surplus.Other is identical with embodiment one.
Embodiment three: present embodiment is different from embodiment one or two: described biological mould inhibitor is comprised of the pure water of natamycin 0.2～2g/L, cyclodextrin 1～2g/L, hydrophilic solvent 100～800g/L and surplus.Other is identical with embodiment one or two.
Embodiment four: present embodiment is different from one of embodiment one to three: described biological mould inhibitor is comprised of the pure water of natamycin 0.2～2g/L, cyclodextrin 0.2～10g/L, hydrophilic solvent 500～700g/L and surplus.Other is identical with one of embodiment one to three.
Embodiment five: present embodiment is different from one of embodiment one to four: described hydrophilic solvent is that quality percentage composition is 95% ethanol.Other is identical with one of embodiment one to four.
Embodiment six: the application of a kind of biological mould inhibitor of present embodiment, it is characterized in that biological mould inhibitor as mould inhibitor for clothing, furniture and metope.
By following examples, verify beneficial effect of the present invention:
Embodiment mono-:
The biological mould inhibitor of present embodiment, the ethanol 500g/L that is 95% by natamycin 0.5g/L, cyclodextrin 1g/L, quality percentage composition and the pure water of surplus form.
First natamycin is dissolved in to quality percentage composition and is in 95% ethanol, cyclodextrin is soluble in water, will after two solution mixing and stirring, obtain biological mould inhibitor.
The dull and stereotyped mould fungus inhibition experiment of the biological mould inhibitor of the present embodiment:
Wash down chain lattice spore, mould, the aspergillus spore on PDA medium, cultivated more than 5 days, making the spore quantity in liquid is 10
6cfu/mL, control group does not add biological mould inhibitor, and spore suspension dilution is coated with dull and stereotyped, after coating evenly, is put in constant incubator, cultivates observed result for 37 ℃, and spore suspension miospore quantity is calculated in colony counting.On each flat board of experimental group, add the biological mould inhibitor of 1mL, shake after even and dry up in clean bench, in each flat board, add the above-mentioned spore suspension of 200uL, after coating evenly, be put in constant incubator, cultivate observed results, the results are shown in Table 1 for 37 ℃.
The biological mould inhibitor of table 1 clothing mould fungus inhibition experimental result on flat board
Above experimental result is the mean of three parallel laboratory tests.
Mould fungus inhibition experiment on cotton:
Mycotic spore under washing is made to 10
5the spore suspension of cfu/mL, is sprayed onto on the cotton of 10cm * 10cm, and control group does not spray mould inhibitor, and experimental group spray mould inhibitor, puts in constant temperature and humidity incubator, and 37 ℃ of humidity of temperature 80% are cultivated observed result, the results are shown in Table 2.
The biological mould inhibitor of table 2 mould fungus inhibition experimental result on cotton
Above experimental result is the mean of three parallel laboratory tests.
Results by above two groups of experiments can be found out, the growth that biological mould inhibitor can 99.9% mould fungus inhibition, the extraordinary anti-mold effect that played.
Embodiment bis-:
The biological mould inhibitor of present embodiment, the ethanol 700g/L that is 95% by natamycin 1.5g/L, cyclodextrin 1g/L, quality percentage composition and the pure water of surplus form.
First natamycin is dissolved in to quality percentage composition and is in 95% ethanol, cyclodextrin is soluble in water, will after two solution mixing and stirring, obtain biological mould inhibitor.
The dull and stereotyped mould fungus inhibition experiment of the biological mould inhibitor of the present embodiment:
Wash down chain lattice spore, mould, the aspergillus spore on PDA medium, cultivated more than 5 days, making the spore quantity in liquid is 10
6cfu/mL, control group does not add biological mould inhibitor, and spore suspension dilution is coated with dull and stereotyped, after coating evenly, is put in constant incubator, cultivates observed result for 37 ℃, and spore suspension miospore quantity is calculated in colony counting.On each flat board of experimental group, add the biological mould inhibitor of 1mL, shake after even and dry up in clean bench, in each flat board, add the above-mentioned spore suspension of 200uL, after coating evenly, be put in constant incubator, cultivate observed results, the results are shown in Table 3 for 37 ℃.
The biological mould inhibitor of table 3 clothing mould fungus inhibition experimental result on flat board
Above experimental result is the mean of three parallel laboratory tests.
Mould fungus inhibition experiment on cotton:
Mycotic spore under washing is made to 10
5the spore suspension of cfu/mL, is sprayed onto on the cotton of 10cm * 10cm, and control group does not spray mould inhibitor, and experimental group spray mould inhibitor, puts in constant temperature and humidity incubator, and 37 ℃ of humidity of temperature 80% are cultivated observed result, the results are shown in Table 4.
The biological mould inhibitor of table 4 mould fungus inhibition experimental result on cotton
Above experimental result is the mean of three parallel laboratory tests.
Results by above two groups of experiments can be found out, the growth that biological mould inhibitor can 100% mould fungus inhibition, the extraordinary anti-mold effect that played.
Claims (6)
1. a biological mould inhibitor, is characterized in that what biological mould inhibitor was comprised of the pure water of natamycin 0.2～2g/L, cyclodextrin 0.2～10g/L, hydrophilic solvent 100～800g/L and surplus.
2. a kind of biological mould inhibitor according to claim 1, is characterized in that what described biological mould inhibitor was comprised of the pure water of natamycin 0.5～1.5g/L, cyclodextrin 0.2～10g/L, hydrophilic solvent 100～800g/L and surplus.
3. a kind of biological mould inhibitor according to claim 1, is characterized in that what described biological mould inhibitor was comprised of the pure water of natamycin 0.2～2g/L, cyclodextrin 1～2g/L, hydrophilic solvent 100～800g/L and surplus.
4. a kind of biological mould inhibitor according to claim 1, is characterized in that what described biological mould inhibitor was comprised of the pure water of natamycin 0.2～2g/L, cyclodextrin 0.2～10g/L, hydrophilic solvent 500～700g/L and surplus.
5. a kind of biological mould inhibitor according to claim 1, is characterized in that described hydrophilic solvent is that quality percentage composition is 95% ethanol.
6. an application for biological mould inhibitor, it is characterized in that biological mould inhibitor as mould inhibitor for clothing, furniture and metope.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201310475600.9A CN103518749A (en) | 2013-10-12 | 2013-10-12 | Biological mildew inhibitor and application thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201310475600.9A CN103518749A (en) | 2013-10-12 | 2013-10-12 | Biological mildew inhibitor and application thereof |
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| CN103518749A true CN103518749A (en) | 2014-01-22 |
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| CN201310475600.9A Pending CN103518749A (en) | 2013-10-12 | 2013-10-12 | Biological mildew inhibitor and application thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105944521A (en) * | 2016-05-21 | 2016-09-21 | 杨勇 | Biologic mould inhibitor |
| CN107114403A (en) * | 2017-06-02 | 2017-09-01 | 合肥华盖生物科技有限公司 | A kind of biological mildew inhibitor and preparation method for leather shoes mildew resistant |
| CN108659709A (en) * | 2018-04-10 | 2018-10-16 | 广西南疆科技服务有限公司 | It is a kind of to remove mould mildew removing agent and preparation method thereof for metope |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1336145A (en) * | 2000-08-01 | 2002-02-20 | 北京市营养源研究所 | Compound biological preservative |
| US20060116335A1 (en) * | 2004-11-26 | 2006-06-01 | Lytone Enterprise, Inc. | Ready-for-complexation composition |
| CN1788558A (en) * | 2004-12-15 | 2006-06-21 | 利统股份有限公司 | Instant complex composition |
| CN1798503A (en) * | 2003-06-02 | 2006-07-05 | 帝斯曼知识产权资产管理有限公司 | Stable aqueous solution of natamycin fungicide |
| CN102986733A (en) * | 2011-09-19 | 2013-03-27 | 孙善家 | Mildewproof and peculiar smell removal agent for storing cleaned clothes |
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2013
- 2013-10-12 CN CN201310475600.9A patent/CN103518749A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1336145A (en) * | 2000-08-01 | 2002-02-20 | 北京市营养源研究所 | Compound biological preservative |
| CN1798503A (en) * | 2003-06-02 | 2006-07-05 | 帝斯曼知识产权资产管理有限公司 | Stable aqueous solution of natamycin fungicide |
| US20060116335A1 (en) * | 2004-11-26 | 2006-06-01 | Lytone Enterprise, Inc. | Ready-for-complexation composition |
| CN1788558A (en) * | 2004-12-15 | 2006-06-21 | 利统股份有限公司 | Instant complex composition |
| CN102986733A (en) * | 2011-09-19 | 2013-03-27 | 孙善家 | Mildewproof and peculiar smell removal agent for storing cleaned clothes |
Non-Patent Citations (1)
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| 贾士儒: "《生物防腐剂》", 30 September 2009, 中国轻工业出版社 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105944521A (en) * | 2016-05-21 | 2016-09-21 | 杨勇 | Biologic mould inhibitor |
| CN107114403A (en) * | 2017-06-02 | 2017-09-01 | 合肥华盖生物科技有限公司 | A kind of biological mildew inhibitor and preparation method for leather shoes mildew resistant |
| CN108659709A (en) * | 2018-04-10 | 2018-10-16 | 广西南疆科技服务有限公司 | It is a kind of to remove mould mildew removing agent and preparation method thereof for metope |
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Application publication date: 20140122 |