CN103495031B - The medicine for the treatment of ulcerative colitis - Google Patents
The medicine for the treatment of ulcerative colitis Download PDFInfo
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- CN103495031B CN103495031B CN201310406109.0A CN201310406109A CN103495031B CN 103495031 B CN103495031 B CN 103495031B CN 201310406109 A CN201310406109 A CN 201310406109A CN 103495031 B CN103495031 B CN 103495031B
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Abstract
The medicine for the treatment of ulcerative colitis, relate to the medicine treating colitis, choose the raw material of following weight: the Radix Astragali 13��17 grams, Radix Codonopsis 13��17 grams, the bighead atractylodes rhizome 13��17 grams, silk 9��15 grams, the sophora bud 7��13 grams, 9��15 grams, sophora flower, myrobalan 9��15 grams, the bletilla striata 9��15 grams, Radix Sangusorbae carbon 25��35 grams, the root of herbaceous peony 13��17 grams, pomegranate rind 9��15 grams, 9��15 grams, Turkey-galls, Red Halloysite 9��15 grams, the banksia rose 7��13 grams, Semen Camelliae 7��13 grams, rattletop 7��13 grams, Chinese cassia tree 3��7 grams, the coptis 3��7 grams, segment or section or grind powder, add water 3000��4000 grams, decoct to three/for the moment, filter residue is liquid. the invention has the beneficial effects as follows: adopt the oral method with bowel lavage, treat both principal and secondary aspect of disease, drug effect is rapid, safe and reliable, curative effect is better. show have efficiency to reach 98.2% with 109 example clinical trials.
Description
Technical field
The present invention relates to medicine, it is the medicine for the treatment of colitis further, particularly treats the Chinese medicine preparation of ulcerative colitis.
Background technology
Ulcerative colitis is also known as chronic non-specific ulcerative colitis, and pathology is positioned at rectum and sigmoid colon more, it is possible to spread to descending colon, even whole colon. Clinical whole symptom for diarrhoea, purulence blood just, stomachache and tenesmus. Modern medicine thinks own cells dysimmunity, mucous membrane is caused to be destroyed, or cause pallium moving obstacle due to mental element, autonomic nervous dysfunction and to produce intestinal movement hyperfunction, intestines vascular smooth myospasm is shunk, tissue ischemia, capillary permeability increases, thus forms the inflammation of intestinal mucosa, erosion and ulcer.
Colitis course of disease length, stubbornness, easily recur, treat quite thorny, be classified as one of modern difficult treatment by the World Health Organization, in recent years in the trend risen gradually. At present, the medicine of western medical treatment ulcerative colitis mainly contains a few class medicines such as sulfamido, antibiotics, hormones, immunosuppressor, said medicine all proves to have reliable result for the treatment of by the long-term test of pesticide effectiveness and clinical trial, but toxicity is big mostly, side effect is many, often there are the symptoms such as nausea and vomiting, headache, general malaise such as oral sulfa drugs, or cause oligoleukocythemia, arthritis, fash, proteinuria etc.; Antibiotic medicine is oral easily causes gastrointestinal irritation, and intravenous administration side effect is big; Immunosuppressor is relatively big on the impact of hemopoietic function of bone marrow, answers periodic review bone marrow smear in medication process.
Therefore, seeking to have result for the treatment of good, the Chinese medicine that untoward reaction is few or Chinese-western medicine mixture just seem very urgently and needs, and the research actively developing this respect has important using value and clinical finger meaning.
Summary of the invention
The object of the present invention is exactly for the defect existed in existing pharmacological agent, it is provided that a kind of treat both principal and secondary aspect of disease, the medicine of drug effect is rapid, safe and reliable, result for the treatment of is good treatment ulcerative colitis, rectitis.
It is an object of the invention to be realized by following scheme:
The medicine for the treatment of ulcerative colitis, it is characterized in that choosing the raw material of following weight: the Radix Astragali 13��17 grams, Radix Codonopsis 13��17 grams, the bighead atractylodes rhizome 13��17 grams, silk 9��15 grams, the sophora bud 7��13 grams, 9��15 grams, sophora flower, myrobalan 9��15 grams, the bletilla striata 9��15 grams, Radix Sangusorbae carbon 25��35 grams, the root of herbaceous peony 13��17 grams, pomegranate rind 9��15 grams, 9��15 grams, Turkey-galls, Red Halloysite 9��15 grams, the banksia rose 7��13 grams, Semen Camelliae 7��13 grams, rattletop 7��13 grams, Chinese cassia tree 3��7 grams, the coptis 3��7 grams, segment or section or grind powder, add water 3000��4000 grams, decoct to three/for the moment, filter residue is liquid.
The present invention can be realized by following scheme further:
Each component the best is: the Radix Astragali 15 grams, Radix Codonopsis 15 grams, the bighead atractylodes rhizome 15 gram, thread 12 grams, the sophora bud 10 grams, 12 grams, sophora flower, myrobalan 12 grams, the bletilla striata 12 grams, Radix Sangusorbae carbon 30 grams, the root of herbaceous peony 15 grams, pomegranate rind 12 grams, 12 grams, Turkey-galls, Red Halloysite 12 grams, the banksia rose 10 grams, Semen Camelliae 10 grams, rattletop 10 grams, Chinese cassia tree 5 grams, the coptis 5 grams, segment or section or grind powder, add water 3500 grams, decoct to three/for the moment, filter residue is liquid.
In the present invention: the Radix Astragali, invigorating QI to consolidate the body surface resistance, diuresis holder poison, apocenosis, expelling pus and promoting granulation, enriches blood, gas in lifting, enhancing body resistibility; Radix Codonopsis, invigorating the spleen and replenishing QI, strong spleen benefit lung; The bighead atractylodes rhizome, air making-up and spleen enlivening, eliminating dampness Li Shui, only sweat, antiabortive; Silk: invigorating the liver and kidney, benefit essence, bright order; The sophora bud, cooling blood for hemostasis, clearing liver-fire; Sophora flower, cooling blood for hemostasis, clearing liver-fire; Myrobalan, puckery intestines hold back lung, fall fire profit pharynx; The bletilla striata, astringing to arrest bleeding, detumescence myogenic; Radix Sangusorbae carbon, garden burnet belongs to hemostatic drug, has cooling blood for hemostasis, removing toxic substances sore effect; It is the common drugs (clinical charcoal of frying is used as medicine more) such as the treatment various hemorrhage and burn due to hot liquid or fire of blood-head; The root of herbaceous peony: flat liver pain relieving, nourishing blood for regulating menstruation, astringing YIN to stop sweating; Pomegranate rind, relieving diarrhea with astringents, hemostasis, expelling parasite; Turkey-galls, holds back lung and falls fire, relieving diarrhea with astringents, holds back sweat hemostasis, hygroscopic sore; Red Halloysite, puckery intestines, hemostasis, promoting tissue regeneration and ulcer healing; The banksia rose, promoting the circulation of QI to relieve pain, strengthening the spleen to promote digestion; Semen Camelliae, promoting the circulation of qi is dredged stagnant; Rattletop, delivers promoting eruption, clearing heat and detoxicating, rises and lifts yang-energy; Chinese cassia tree, mends fire supporing yang, and ignite Gui Yuan, dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow; The coptis, heat-clearing and damp-drying drug, eliminating fire and detoxication.
The configuration mechanism of the present invention: the Radix Astragali, Radix Codonopsis, the bighead atractylodes rhizome (stir-fry) replenish qi to invigorate the spleen; The sub flat kidney tonifying of silk is first; The sophora bud (stir-fry), sophora flower (stir-fry) freeze blood hemostasis dissipating blood stasis for subsidence of swelling; Myrobalan, pomegranate rind, Red Halloysite antidiarrheal kill intestinal bacteria; Bletilla striata myogenic is put on flesh hemostasis; Radix Sangusorbae carbon stops blooding; The root of herbaceous peony is nourished blood relieving pain by regulating nutrient QI; Turkey-galls cooling blood for hemostasis relieving diarrhea with astringents; Woody note conductance is stagnant; Stagnation pain antidiarrheal is led in Semen Camelliae promoting the circulation of qi; Rattletop, Chinese cassia tree benefiting qi and raising yang; Coptis heat-clearing and damp-drying drug, eliminating fire and detoxication. All medicine compatibilities of the present invention have effect such as gas, antisepsis and anti-inflammation, enhancing body resistibility in clearing heat and detoxicating, cooling blood for hemostasis, removing necrosis, promoting granulation, lifting.
The invention has the beneficial effects as follows: adopt the oral method with bowel lavage with this medicine, treatment ulcerative colitis, rectitis, the through sick institute of medicine, local Plasma Concentration in intestines can be improved, the availability of medicine obtains and gives full play to, and better reaches clearing heat and detoxicating, cooling blood for hemostasis, removing necrosis, promoting granulation, antisepsis and anti-inflammation, makes that local is congested, oedema is comparatively fast recovered, the healing of local curing ulcer erosion, thus reach therapeutic purpose. Medicine of the present invention, treats both principal and secondary aspect of disease, drug effect is rapid, safe and reliable, curative effect is better. Show have efficiency to reach 98.2% with 109 example clinical trials.
Testing data:
1, cure mainly: ulcerative colitis.
2, case statistics: treat in 109 examples, the male sex 81 example, women 28 example, age structure is: less than 30 years old 21 example, 31��40 years old 28 example, 41��50 years old 26 example, 50��60 years old 20 example, more than 60 years old 14 example, max age 73 years old, minimal ages 22 years old; The course of disease is the shortest 1 year, the longest 12 years.
3, methods for the treatment of: adult oral 250 milliliters every time, 150 milliliters, bowel lavage, every day oral twice, twice, bowel lavage. It within 30 days, it is a course for the treatment of. Each course for the treatment of 3��7 days, interval, can again with the next course for the treatment of. General 1��2 the course for the treatment of clinical symptom just can substantially disappear. Afterwards, re-use 1��3 course for the treatment of, consolidate curative effect, to prevent recurrence.
4, contraindication: between medication period, avoids eating anything raw or cold, pungent greasy, nondigestible food, does not have a bath with cold water. Pregnant woman is forbidden, and this product allergy sufferers is forbidden.
5, efficacy assessment standard:
Curing: purulence blood just disappears, stomachache disappears, and stool recovers normal. Taking a turn for the better: purulence blood just reduces, and stomachache alleviates, diarrhoea number of times reduces. Invalid: not reach improvement target person.
6, result for the treatment of:
The shortest 21 days, the longest 90 days, 63 examples are cured in medication, account for 57.8%; Take a turn for the better 44 examples, accounts for 40.4%; Invalid 2 examples, account for 1.8%; Always there is efficiency 98.2%.
7, model case introduction:
Case 1: ox so-and-so, man, 41 years old, live Changyuan County, Henan Province. In September, 2011 goes to a doctor, and through multiple hospitals, intestines mirror is made a definite diagnosis, and suffers from colorectum ulcer 7 years, through multi-treatment less effective, starts to show as tenesmus, and just purulence is had blood in stool often. Adding enema treatment with this medicine is oral, within 10 days, have positive effect, purulence blood obviously reduces, and adheres to treatment 2 months, and clinical symptom all disappears. Recurrence that so far there are no.
Case 2: Lee so-and-so, man, 56 years old, lives Hua County, Henan Province Lao Miaoxiang, and recurrent exerbation stomachache, diarrhoea, purulence blood is just after 2 months, does colonoscopy in March, 2010 to hospital of counties and cities, is diagnosed as ulcerative colitis. Oral with bowel lavage with this medicine, after 1 course for the treatment of, purulence blood just disappears substantially. Treat 2 courses for the treatment of, clinical symptom disappearance. Recurrence that so far there are no.
In order to make those skilled in the art understand the present invention program better, and the above-mentioned purpose of the present invention, feature and advantage being become apparent more, below in conjunction with embodiment, the present invention is further detailed explanation.
Embodiment
Embodiment 1:
Choose the Radix Astragali 13 grams, Radix Codonopsis 13 grams, the bighead atractylodes rhizome 13 gram, thread 9 grams, the sophora bud 7 grams, 9 grams, sophora flower, myrobalan 9 grams, the bletilla striata 9 grams, Radix Sangusorbae carbon 25 grams, the root of herbaceous peony 13 grams, pomegranate rind 9 grams, 9 grams, Turkey-galls, Red Halloysite 9 grams, the banksia rose 7 grams, Semen Camelliae 7 grams, rattletop 7 grams, Chinese cassia tree 3 grams, the coptis 3 grams, segment or section or grind powder, add water 3000 grams, decoct to three/for the moment, filter residue is liquid.
Embodiment 2:
Choose the Radix Astragali 17 grams, Radix Codonopsis 17 grams, the bighead atractylodes rhizome 17 gram, thread 15 grams, the sophora bud 13 grams, 15 grams, sophora flower, myrobalan 15 grams, the bletilla striata 15 grams, Radix Sangusorbae carbon 35 grams, the root of herbaceous peony 17 grams, pomegranate rind 15 grams, 15 grams, Turkey-galls, Red Halloysite 15 grams, the banksia rose 13 grams, Semen Camelliae 13 grams, rattletop 13 grams, Chinese cassia tree 7 grams, the coptis 7 grams, segment or section or grind powder, add water 4000 grams, decoct to three/for the moment, filter residue is liquid.
Embodiment 3:
Choose the Radix Astragali 15 grams, Radix Codonopsis 15 grams, the bighead atractylodes rhizome 15 gram, thread 12 grams, the sophora bud 10 grams, 12 grams, sophora flower, myrobalan 12 grams, the bletilla striata 12 grams, Radix Sangusorbae carbon 30 grams, the root of herbaceous peony 15 grams, pomegranate rind 12 grams, 12 grams, Turkey-galls, Red Halloysite 12 grams, the banksia rose 10 grams, Semen Camelliae 10 grams, rattletop 10 grams, Chinese cassia tree 5 grams, the coptis 5 grams, segment or section or grind powder, add water 3500 grams, decoct to three/for the moment, filter residue is liquid.
In each embodiment, the bighead atractylodes rhizome refers to that Rhizoma Atractylodis Macrocephalae (parched), the sophora bud refer to fry the sophora bud, sophora flower refers to fry sophora flower, the root of herbaceous peony refers to Radix Paeoniae Alba (parched).
The above; it is only the specific embodiment of the present invention, but protection scope of the present invention is not limited thereto, any it is familiar with those skilled in the art in the technical scope that the present invention discloses; the change that can expect easily or replacement, all should be encompassed within protection scope of the present invention.
Claims (3)
1. treat the medicine of ulcerative colitis, it is characterized in that choosing the raw material of following weight: the Radix Astragali 13��17 grams, Radix Codonopsis 13��17 grams, the bighead atractylodes rhizome 13��17 grams, silk 9��15 grams, the sophora bud 7��13 grams, 9��15 grams, sophora flower, myrobalan 9��15 grams, the bletilla striata 9��15 grams, Radix Sangusorbae carbon 25��35 grams, the root of herbaceous peony 13��17 grams, pomegranate rind 9��15 grams, 9��15 grams, Turkey-galls, Red Halloysite 9��15 grams, the banksia rose 7��13 grams, Semen Camelliae 7��13 grams, rattletop 7��13 grams, Chinese cassia tree 3��7 grams, the coptis 3��7 grams, segment or section or grind powder, add water 3000��4000 grams, decoct to three/for the moment, filter residue is liquid.
2. the medicine for the treatment of ulcerative colitis according to claim 1, it is characterized in that each component is: the Radix Astragali 15 grams, Radix Codonopsis 15 grams, the bighead atractylodes rhizome 15 gram, thread 12 grams, the sophora bud 10 grams, 12 grams, sophora flower, myrobalan 12 grams, the bletilla striata 12 grams, Radix Sangusorbae carbon 30 grams, the root of herbaceous peony 15 grams, pomegranate rind 12 grams, 12 grams, Turkey-galls, Red Halloysite 12 grams, the banksia rose 10 grams, Semen Camelliae 10 grams, rattletop 10 grams, Chinese cassia tree 5 grams, the coptis 5 grams, segment or section or grind powder, add water 3200 grams, decoct to three/for the moment, filter residue is liquid.
3. the medicine for the treatment of ulcerative colitis according to claim 1 and 2, it is characterised in that the bighead atractylodes rhizome refers to that Rhizoma Atractylodis Macrocephalae (parched), the sophora bud refer to fry the sophora bud, sophora flower refers to fry sophora flower, the root of herbaceous peony refers to Radix Paeoniae Alba (parched).
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| CN201310406109.0A CN103495031B (en) | 2013-09-09 | 2013-09-09 | The medicine for the treatment of ulcerative colitis |
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| CN201310406109.0A CN103495031B (en) | 2013-09-09 | 2013-09-09 | The medicine for the treatment of ulcerative colitis |
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| CN103495031B true CN103495031B (en) | 2016-06-01 |
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Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103736000B (en) * | 2014-02-08 | 2016-03-23 | 范红霞 | A kind of Chinese medicine for the treatment of yang deficiency of spleen and stomache ulcerative colitis |
| CN105168904A (en) * | 2015-08-31 | 2015-12-23 | 李丽芬 | Traditional Chinese medicine preparation for treating chronic gastric ulcer or duodenal ulcer |
| CN106581547A (en) * | 2017-02-21 | 2017-04-26 | 陈秋生 | Traditional Chinese medicine composition for treating enteritis in general surgery |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1634303A (en) * | 2004-11-08 | 2005-07-06 | 王献美 | Medicine capsule for treating ulcerative colitis |
| CN101700358A (en) * | 2009-11-12 | 2010-05-05 | 林喜彬 | Medicine for treating acute and chronic nonspecific ulcerative colitis and preparation method thereof |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1634303A (en) * | 2004-11-08 | 2005-07-06 | 王献美 | Medicine capsule for treating ulcerative colitis |
| CN101700358A (en) * | 2009-11-12 | 2010-05-05 | 林喜彬 | Medicine for treating acute and chronic nonspecific ulcerative colitis and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 溃疡性结肠炎中医药治疗进展;黄烈生;《黑龙江中医药》;20011231(第03期);63-65 * |
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