CN104721572B - A kind of Chinese medicine for treating chronic colitis - Google Patents

A kind of Chinese medicine for treating chronic colitis Download PDF

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CN104721572B
CN104721572B CN201510180335.0A CN201510180335A CN104721572B CN 104721572 B CN104721572 B CN 104721572B CN 201510180335 A CN201510180335 A CN 201510180335A CN 104721572 B CN104721572 B CN 104721572B
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parts
grams
chronic colitis
fruit
chinese medicine
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CN104721572A (en
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郎召君
莫宗伟
刘美珍
王景明
郑于静
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Hainan Wanzhou Green Pharmaceutical Co ltd
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Abstract

The present invention relates to a kind of Chinese medicines for treating chronic colitis, are prepared by the medicinal material of following weight proportion:5 parts of dianthus superbus, 8 parts of caulis lonicerae, 3 parts of the sterculia seed, 5 parts of Glabrous Sarcandra Herb, 8 parts of eclipta, 7 parts of the fruit of summer cypress, 4 parts of Herba Euphorbiae Humifusae, 10 parts of panax ginseng fruit, 12 parts of rainbow conk, 3 parts of shepherd's purse, 2 parts of semen astragali complanati, 5 parts of Chinese actinidia root.Clinical experiments have proved that the present invention can safely and effectively treat chronic colitis.

Description

A kind of Chinese medicine for treating chronic colitis
Technical field
The present invention relates to a kind of Chinese medicines, more particularly, to a kind of Chinese medicine for treating chronic colitis.
Background technique
Chronic colitis is a kind of chronic, repeatability, multiple using colon, sigmoid colon and rectum as site of pathological change.Refer to Rectum colon leads to the inflammatory edema of enteron aisle, ulcer, bleeding lesion because of various pathogenesis.Symptom is left lower quadrant pain, diarrhea, inner Weight after urgency, when be just stained with liquid, constipation or diarrhea down and alternately occur, be good or bad, touching lower disconnected, recurrent exerbation.This disease, which is seen, appoints What at age, but 20~30 years old is most common.
Still lack the effective therapeutic agent of generally recognized as safe at present for chronic colitis at present.
The present Research of medicinal material involved by Chinese medicine of the present invention is as follows:
Dianthus superbus
【Source】For pinkwort dianthus superbus or the wounded in the battle herb of China pink.
【Major function】Clearing away heat and promoting diuresis, blood-breaking promoting menstruation.
【Usage and dosage】It is for oral administration:Decoction, 1.5~3 money
Caulis lonicerae
【Source】This product is the drying stem branch of caprifoliaceae plant honeysuckle Lonicera japonica Thunb..
【Major function】It is clearing heat and detoxicating, dispelling wind dredging collateral.
【Usage and dosage】9~30g.
The sterculia seed
【Source】For the seed of the Sterculiaceae plant sterculia seed.
【Major function】Clearing heat and moistening lung, liyan jiedu, relax bowel and defecation.
【Usage and dosage】It is for oral administration:Decoction, 1.5~3 money;Or it makes tea.
Glabrous Sarcandra Herb
【Source】For golden chestnut orchid Chloranthus glaber Sarcandra glabra(Thunb.)The complete stool of Nakai.
【Major function】Dispelling wind and eliminating dampness;Promoting blood circulation to remove blood stasis;It is clearing heat and detoxicating.
【Usage and dosage】It is for oral administration:Decoction, 9-15g
Eclipta
【Source】For the herb of compositae plant Eclipta prostrata.
【Major function】It tonifies the liver and kidney;Cooling blood and hemostasis.
【Usage and dosage】It is for oral administration:Decoction, 9-30g
The fruit of summer cypress
【Source】This product is chenopod summer cypress Kochia scoparia(L.)Schrad. dry mature fruit.
【Major function】Clearing heat and promoting diuresis, dispelling wind and arresting itching.
【Usage and dosage】9~15g.
Herba Euphorbiae Humifusae
【Source】For the herb of euphorbia plant Herba Euphorbiae Humifusae.
【Major function】It is clearing heat and detoxicating, cooling blood and hemostasis.
【Usage and dosage】It is for oral administration:Decoction, 10-15g
Panax ginseng fruit
【Source】For the whole herb with root of orchid musk orchid.
【Major function】Heart tonifying kidney tonifying, promotes the production of body fluid to quench thirst, good efficacy to suffering from a deficiency of the kidney, regulating menstruation and activating blood.
【Usage and dosage】It is for oral administration:Decoction, 3~4 money
Rainbow conk
【Source】Medicine elementary source:For the fructification of On Polyporaceae Corilus versicolor Quel..
【Major function】Invigorating spleen to remove dampness;It is relieving cough and asthma;It is clearing heat and detoxicating.
【Usage and dosage】It is for oral administration:Decoction, 15-30g.
Shepherd's purse
【Source】For the whole herb with root of crucifer shepherd's purse.
【Major function】Cool liver hemostasis;With spleen Li Shui;Clearing heat and promoting diuresis.
【Usage and dosage】It is for oral administration:Decoction, 3~5 money
Semen astragali complanati
【Source】For the seed of leguminous plant astragatus complanatus or Astragalus sinensis.
【Major function】Tonifying liver, kidney-nourishing, improving eyesight, controlling nocturnal emission with astringent drugs.
【Usage and dosage】It is for oral administration:Decoction, 2~3 money
Chinese actinidia root
【Source】This product is the root of Chinese gooseberry section plant Chinese gooseberry.
【Major function】It is clearing heat and detoxicating, dispelling wind and eliminating dampness, diuresis hemostasis.
【Usage and dosage】Five Qian Zhiyi two, decoction.
Summary of the invention
The present invention is intended to provide a kind of Chinese medicine for treating chronic colitis is reached by selecting suitable medicinal material and its proportion To the safe and effective purpose for curing chronic colitis.
In order to achieve the above object, the present invention uses following technical scheme:
A kind of Chinese medicine for treating chronic colitis, which is characterized in that be prepared by the medicinal material of following weight proportion:Dianthus superbus 5 parts, 8 parts of caulis lonicerae, 3 parts of the sterculia seed, 5 parts of Glabrous Sarcandra Herb, 8 parts of eclipta, 7 parts of the fruit of summer cypress, 4 parts of Herba Euphorbiae Humifusae, 10 parts of panax ginseng fruit, cloud 12 parts of sesame, 3 parts of shepherd's purse, 2 parts of semen astragali complanati, 5 parts of Chinese actinidia root.
The beneficial effects of the present invention will now be described with reference to clinical experimental data:
1, general information
The out-patient of 76 chronic colitis, age 21-53 are collected between inventor's in November, 2012 in September, -2014 altogether Year, the course of disease -1 year 2 months.It is randomly divided into:Treatment group 53, blank group 23.The data such as two groups of ages, state of an illness are poor without conspicuousness It is different, it is comparable.
2, test method
The oral present invention of 2.1 treatment groups is according to capsule made from specific embodiment 1, once in the morning and once at night, the course for the treatment of 10 days.
2.2 blank group oral placebo capsules, once in the morning and once at night.The course for the treatment of 10 days.
3, criterion of therapeutical effect and treatment results
3.1 criterion of therapeutical effect
For chronic colitis efficacy evaluation:
Recovery from illness:Phenomena such as clinical symptoms, that is, symptom of digestive tract improves, diarrhea, abdominal pain and constipation all disappears, laboratory's inspection It looks into normally, observation has no repeatedly for three months.
It improves:Phenomena such as clinical symptoms, that is, symptom of digestive tract improves, diarrhea, abdominal pain and constipation mitigates, and the state of an illness is controlled, Laboratory checks improvement or normal.
In vain:The no significant improvement or aggravations such as phenomena such as clinical symptoms, that is, symptom of digestive tract, diarrhea, abdominal pain and constipation.
4.2 treatment statistics are shown in Table 1.
1 two groups of curative effects of table compare
Group n Recovery from illness It improves In vain Total effective rate(%) Adverse reaction example
Treatment group 53 34(64.1%) 15(28.3%) 4(7.5%) 92.5% 0
Blank group 23 0(0%) 3(13.0%) 20(87.0%) 13.0% 0
To demonstrate that the invention has good curative effect, it lists typical cases as follows:
1, Liu, male, 22 years old, students, I told that recent symptom of digestive tract takes place frequently, and predominantly discontinuity abdomen is hidden Bitterly, distending pain etc., especially after feeding greasy based food, pain phenomenon is become apparent, while times of defecation also increased, sometimes One day up to tens of times, then go to local hospital medical in time, hospital is diagnosed as slowly by inspections such as blood examination, excrement inspection, Sigmoidoscopes Property colitis disease, effect does not have material alterations after a week using doctor trained in Western medicine routine medication for rear hospital, and pain symptom has increasing nothing Subtract trend.After give Chinese medicine of the present invention treatment, after taking a course for the treatment of, pain symptom is substantially reduced etc., continues with after three courses for the treatment of, sick Feelings are clearly better recovery from illness, have no recurrence so far.
2, it is lucky certain, female, 31 years old, first visit on May 12 in 2014.He or she main suit:Recent fever, cramp, evil Heart vomiting, stool urgently as water or it is viscous freeze bloody stool shape, meanwhile, lustreless complexion is simultaneously afraid of with lassitude, limbs fatigue, happiness temperature The symptoms such as cold.Then go to local hospital in time, hospital is then diagnosed as by colonoscopy, drink bowel lavage x ray photograph inspection etc. Chronic colitis disease, hospital, which uses, carries out anti-inflammatory analgetic with antibiotic, and the symptoms such as anti-infective therapy are not alleviated.After give Chinese medicine treatment of the present invention is given, after taking a course for the treatment of, pain phenomenon gradually mitigates, after continuing taking the two courses, state of an illness rehabilitation Completely, and so far without recurrence.
3, it is neat so-and-so, male, 38 years old, my main suit's abdominal pain unbearably, had times of defecation to increase obvious, and be in diarrhea in the recent period Constipation is alternately present, meanwhile, excrement matter mostly in the pasty state, is mixed with a large amount of mucus, often band purulence blood.Period has to be controlled by modes such as Chinese medicines It treats, but is not alleviated.Now go to local institute of traditional Chinese medicine to classify by tcm syndrome and be diagnosed as it and belong to chronic colitis, and thinks It is wet etc. with speen-kidney dificiency folder, Chinese medicine conventional therapy is used after hospital, symptom is not felt any better after a week.Then give in the present invention Medicine treatment, after taking a course for the treatment of, abdominal pain sense is significantly reduced, and after taking three courses for the treatment of, the reaction of patient's various aspects is good, there is no multiple Hair, and can be carried out normal work, life.
As it can be seen that the present invention uses scientific formula and suitable proportion, cooperate between each drug, acts synergistically, adopt It is reinforced the kidney with clearing heat and promoting diuresis, dissolving blood stasis and detoxication, invigorating the spleen to treat big method, made Chinese medicine can safely and effectively treat chronic knot Enteritis.
Specific embodiment
In order to better understand and implement the present invention, the present invention is further illustrated combined with specific embodiments below.
Specific embodiment 1
It weighs:5 grams of dianthus superbus, 8 grams of caulis lonicerae, 3 grams of the sterculia seed, 5 grams of Glabrous Sarcandra Herb, 8 grams of eclipta, 7 grams of the fruit of summer cypress, Herba Euphorbiae Humifusae 4 grams, 10 grams of panax ginseng fruit, 12 grams of rainbow conk, 3 grams of shepherd's purse, 2 grams of semen astragali complanati, 5 grams of Chinese actinidia root add 8 times of amount water, decoct 1.5 hours, mistake Filter;Filter residue adds 6 times of amount water, decocts 1 hour, filtering;Merging filtrate is concentrated, dry, be packed into capsule shells to get meet normally at The capsule of 1 day dosage of people.
For treating chronic colitis.Oral, every bu is taken twice sooner or later.
Specific embodiment 2
It weighs:5 grams of dianthus superbus, 8 grams of caulis lonicerae, 3 grams of the sterculia seed, 5 grams of Glabrous Sarcandra Herb, 8 grams of eclipta, 7 grams of the fruit of summer cypress, Herba Euphorbiae Humifusae 4 grams, 10 grams of panax ginseng fruit, 12 grams of rainbow conk, 3 grams of shepherd's purse, 2 grams of semen astragali complanati, 5 grams of Chinese actinidia root add 8 times of amount water, decoct 1.5 hours, mistake Filter;Filter residue adds 6 times of amount water, decocts 1 hour, filtering;Merging filtrate, concentration, dry, pulverize to get 1 day use of normal adult is met The powder of amount.
For treating chronic colitis.Oral, every bu is taken twice sooner or later.
Specific embodiment 3
It weighs:5 grams of dianthus superbus, 8 grams of caulis lonicerae, 3 grams of the sterculia seed, 5 grams of Glabrous Sarcandra Herb, 8 grams of eclipta, 7 grams of the fruit of summer cypress, Herba Euphorbiae Humifusae 4 grams, 10 grams of panax ginseng fruit, 12 grams of rainbow conk, 3 grams of shepherd's purse, 2 grams of semen astragali complanati, 5 grams of Chinese actinidia root add 8 times of amount water, decoct 1.5 hours, mistake Filter;Filter residue adds 6 times of amount water, decocts 1 hour, filtering;Merging filtrate is concentrated, dry, adds appropriate dextrin and corrigent, presses It pelletizes according to this field common process, packaging can be prepared by the granule for meeting 1 day dosage of normal adult.
For treating chronic colitis.Oral, every bu is taken twice sooner or later.

Claims (1)

1. a kind of Chinese medicine for treating chronic colitis, which is characterized in that be prepared by the medicinal material of following weight proportion:Dianthus superbus 5 Part, 8 parts of caulis lonicerae, 3 parts of the sterculia seed, 5 parts of Glabrous Sarcandra Herb, 8 parts of eclipta, 7 parts of the fruit of summer cypress, 4 parts of Herba Euphorbiae Humifusae, 10 parts of panax ginseng fruit, cloud 12 parts of sesame, 3 parts of shepherd's purse, 2 parts of semen astragali complanati, 5 parts of Chinese actinidia root.
CN201510180335.0A 2015-04-16 2015-04-16 A kind of Chinese medicine for treating chronic colitis Active CN104721572B (en)

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Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4169966B2 (en) * 2001-11-14 2008-10-22 株式会社ヤクルト本社 Inflammatory bowel disease preventive and therapeutic agent

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
二藤芩术汤治疗慢性结肠炎50例;朱柏林;《浙江中医杂志》;19940531(第5期);第207页 *
云芝肝泰和西咪替丁联用治疗溃疡性结肠炎25例;陈宏伟等;《世界华人消化杂志》;19981231;第6卷(第11期);第1009页 *
肿节风治疗慢性非特异性溃疡性结肠炎2例;张家振;《中医杂志》;19821231(第10期);第45页 *

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Inventor after: Lang Zhaojun

Inventor after: Mo Zongwei

Inventor after: Liu Meizhen

Inventor after: Wang Jingming

Inventor after: Zheng Yujing

Inventor before: Wang Jingming

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Address after: 325000 Wenchang Road, locheng Town, Yueqing, Wenzhou, Zhejiang

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Address after: 233700 Room 202, 2nd Floor, North Courtyard Complex Building, Mopan Zhangming Street, Xinmaqiao Town, Guzhen County, Bengbu City, Anhui Province

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Address before: Yueqing City, Zhejiang Province, Yuecheng Town, Wenzhou City, Wenchang road 325000

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Patentee after: HAINAN WANZHOU GREEN PHARMACEUTICAL Co.,Ltd.

Address before: Room 202, second floor, complex building, north yard, supply and marketing cooperative, Mopan zhangwenming street, xinmaqiao Town, Guzhen County, Bengbu City, Anhui Province

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Denomination of invention: A Traditional Chinese Medicine for Treating Chronic Colitis

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