CN103736000B - A kind of Chinese medicine for the treatment of yang deficiency of spleen and stomache ulcerative colitis - Google Patents
A kind of Chinese medicine for the treatment of yang deficiency of spleen and stomache ulcerative colitis Download PDFInfo
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Abstract
Treat a Chinese medicine for yang deficiency of spleen and stomache ulcerative colitis, this Chinese medicine is made up of Fructus Viburni Ceanothoidis, Herba Pteridis disparis, Cortex querci dentatae, Fructus Armeniacae Mume, Rhizoma Cimicifugae, Fructus Mahoniae, Potentilla sericea L.(Potentilla poteroides Franch), Radix Achyranthis, Fructus Tsaoko, the Radix Astragali.Clinical can be used for, treats yang deficiency of spleen and stomache ulcerative colitis.
Description
Technical field
The invention belongs to technical field of Chinese medicines, especially relate to a kind of Chinese medicine for the treatment of yang deficiency of spleen and stomache ulcerative colitis.
Background technology
Ulcerative colitis (UC) has become China's digestive system common disease, and World Health Organization (WHO) is also classified as it as one of modern difficult treatment.Motherland's medical science thinks that the origin cause of formation of primary disease is intemperance of taking food, dysfunction of the spleen in transportation, aquation are wet, and paddy is anti-stagnant, stops or invades in exopathogen, impairing the spleen and stomach, inside and outside addition in humidity hysteresis, and cause damp and hot stagnating to pent up intestinal, QI and blood blocks and causes.Current etiology unknown, general western medicine therapy can bring very large side effect to health.Long-term practice through inventor finds, treatment by Chinese herbs yang deficiency of spleen and stomache ulcerative colitis of the present invention has better effect, obtains good effect.
Summary of the invention
The object of the present invention is to provide that a kind of therapeutic effect is good, effective percentage is high, Chinese medicine to the treatment yang deficiency of spleen and stomache ulcerative colitis of human non-toxic's side effect.
The object of the present invention is achieved like this, according to Chinese medical theory, utilizing the property of medicine of Chinese medicine uniqueness, adopting Fructus Viburni Ceanothoidis, Herba Pteridis disparis, Cortex querci dentatae, Fructus Armeniacae Mume, Rhizoma Cimicifugae, Fructus Mahoniae, Potentilla sericea L.(Potentilla poteroides Franch), Radix Achyranthis, Fructus Tsaoko, the Radix Astragali according to certain compatibility requirement, through being processed into.
Prepare Chinese medicine of the present invention and make Fructus Viburni Ceanothoidis 30-40 part, Herba Pteridis disparis 20-30 part, Cortex querci dentatae 20-30 part, Fructus Armeniacae Mume 15-25 part, Rhizoma Cimicifugae 15-25 part, Fructus Mahoniae 15-25 part, Potentilla sericea L.(Potentilla poteroides Franch) 15-25 part, Radix Achyranthis 10-20 part, Fructus Tsaoko 10-20 part, Radix Astragali 10-15 part by following raw material medicaments.
Optimum weight part of raw material of Chinese medicine medicine of the present invention is: Fructus Viburni Ceanothoidis 35 parts, Herba Pteridis disparis 25 parts, Cortex querci dentatae 25 parts, Fructus Armeniacae Mume 20 parts, Rhizoma Cimicifugae 20 parts, Fructus Mahoniae 20 parts, Potentilla sericea L.(Potentilla poteroides Franch) 20 parts, Radix Achyranthis 15 parts, Fructus Tsaoko 15 parts, the Radix Astragali 12 parts.
The pharmacological action of Chinese medicine of the present invention is as follows:
Fructus Viburni Ceanothoidis: sweet, micro-hardship, micro-puckery, flat.Removing toxic substances, hemostasis, antidiarrheal.Clinical in enteritis, dysentery, metrorrhagia, threatened abortion, the diseases such as urticaria.
Herba Pteridis disparis: bitter, puckery, cool.Return liver, large intestine channel.Heat-clearing and toxic substances removing, blood stasis dispelling removing heat from blood.Clinical in dysentery, have loose bowels, mumps, rheumatic arthralgia, traumatic injury, carbuncle pyogenic infections from tumour or sore, the diseases such as venom.
Cortex querci dentatae: bitter, puckery, flat.Removing toxic substances and promoting subsidence of swelling, astringing intestine to stop diarrhea, hemostasis.Clinical in sore, carbuncle and painful swelling, diabrosis is not held back, scrofula, hemorrhoid, dysentery, discharging fresh blood stool etc.
Fructus Armeniacae Mume: sour, puckery, salty.Return Liver and kidney warp.Sore-throat relieving promotes the production of body fluid, relieving diarrhea with astringents, and expectorant is opened and kept silent.Clinical in laryngopharynx swelling and pain, excessive thirst vomiting and nausea, chronic diarrhea chronic dysentery, has blood in stool, metrorrhagia, apoplexy infantile convulsion, globus hystericus, swollen ulcer drug, the diseases such as traumatic hemorrhage.
Rhizoma Cimicifugae: pungent, sweet, be slightly cold, returns lung, spleen, stomach, large intestine channel.Deliver rash, heat-clearing and toxic substances removing, elevate a turnable ladder yang-energy.For headache due to pathogenic wind-heat, measles without adequate eruption, laryngopharynx swelling and pain, collapse of QI, chronic diarrhea proctoptosis, metrostaxis etc.
Fructus Mahoniae: bitter, cool.Return spleen, kidney, urinary bladder channel.Clearind deficient heat, the kidney invigorating, dampness.For osteopyrexia and fever, soreness of the waist and knees, dizziness and tinnitus, damp-heat diarrhea, leukorrhagia, the diseases such as stranguria with turbid discharge.
Potentilla sericea L.(Potentilla poteroides Franch): sweet, warm.Return kidney channel.Strengthening spleen, tonifying kidney, arresting sweating, hemostasis.Clinical in weakness due to chronic disease, night sweat due to yin deficiency, metrorrhagia, is with inferior disease.
Radix Achyranthis: sweet, micro-hardship, micro-acid, cold in nature.Return liver, kidney channel.Blood circulation promoting and blood stasis dispelling, eliminating fire and detoxication, inducing diuresis for treating stranguria syndrome.For amenorrhea, traumatic injury, Fengshi Guanjie pain, dysentery, diphtheria, laryngopharynx swelling and pain, the diseases such as edema.
Fructus Tsaoko: pungent, warm.Return spleen, stomach warp.Dampness warming middle-JIAO, eliminate the phlegm preventing the attack (or recurrence) of malaria.Clinical in coldness and pain in the epigastrium, nausea and vomiting, born of the same parents' diaphragm feeling of fullness, has loose bowels, the diseases such as malaria.
The Radix Astragali: sweet, warm, returns lung, spleen channel.Benefiting qi and raising yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, promoting pus discharge and tissue regeneration strengthening.For diarrhea due to hypofunction of the spleen, wait the card of all Qi and blood deficiencies.
The differential diagnosis of diseases of the yang deficiency of spleen and stomache ulcerative colitis traditional Chinese medical science belongs to the category such as " having loose bowels ", " Hakuri ".Clinical symptoms is with chronic diarrhea, stomachache, and row's mucus is just, hemafecia is main, and in chronic repeatability outbreak or persistence outbreak, the primary disease course of disease is longer, how because of chronic dietary accidentally, overstrain internal injury, cause weakness of the spleen and stomach.In the present invention, Fructus Viburni Ceanothoidis removing toxic substances, antidiarrheal, be monarch drug; Herba Pteridis disparis heat-clearing and toxic substances removing, Cortex querci dentatae removing toxic substances and promoting subsidence of swelling, astringing intestine to stop diarrhea are ministerial drug; Fructus Armeniacae Mume relieving diarrhea with astringents, Rhizoma Cimicifugae heat-clearing and toxic substances removing, elevate a turnable ladder yang-energy, Fructus Mahoniae clearind deficient heat, the kidney invigorating, Potentilla sericea L.(Potentilla poteroides Franch) strengthening spleen, tonifying kidney, Radix Achyranthis detoxifies, Fructus Tsaoko warming middle-JIAO, Radix Astragali benefiting qi and raising yang, consolidating superficial resistance.Find, to yang deficiency of spleen and stomache ulcerative colitis, there is unique curative effect through clinical practice, reach the object for the treatment of yang deficiency of spleen and stomache ulcerative colitis.
Chinese medicine of the present invention was in 2005 to 2011 the routine patients of clinical observation yang deficiency of spleen and stomache ulcerative colitis 59, and clinical report is as follows:
1, physical data
In 59 routine patients, in age 40-63 year, the course of disease is many at 8 months to 8 years, 51 years old mean age.
2, diagnostic criteria
" Chinese medical disease Standardization of diagnosis and curative effect " that State Administration of Traditional Chinese Medicine issues:
Yang deficiency of spleen and stomache ulcerative colitis symptom: primary symptom: (1) chronic diarrhea is not healed, defecates rare clear or with die-hard; (2) soreness of the waist and knees; (3) lack of appetite poor appetite; (4) pale tongue, fat or have indentation, white and moist fur; (5) deep-thready pulse or CHI-pulse being weak.Secondary disease: (1) diarrhea before dawn or rushed down before dawn; (2) Qizhong stomachache, likes warm pain relieved by pressing; (3) coldness of the body with chills; (4) abdominal swelling; (5) deficiency of QI with disinclination to talk; (6) pale complexion; (7) intestinal mucosa edema is obviously more congested; (8) shallow, red and swollen not obvious, the superficial white secretions of periphery of intestinal mucosa ulcer table; (9) D-xylitol excretion rate reduces; (10) urine 17-hydroxycorticosteroid, urine-17 ketosteroid output, reduce.Possesses primary symptom 2, secondary disease 2; Or primary symptom the 1st, secondary disease 3.
3, Therapeutic Method
3.1 prescriptions: Fructus Viburni Ceanothoidis 35g, Herba Pteridis disparis 25g, Cortex querci dentatae 25g, Fructus Armeniacae Mume 20g, Rhizoma Cimicifugae 20g, Fructus Mahoniae 20g, Potentilla sericea L.(Potentilla poteroides Franch) 20g, Radix Achyranthis 15g, Fructus Tsaoko 15g, Radix Astragali 12g.
3.2 methods of preparation and use: said medicine routinely technique makes decoction, every day 1 dose, every day 2 times 25 days was 1 course for the treatment of.
4, therapeutic outcome:
4.1 formulate with reference to " Chinese medicine Clinical Researches of New Drugs guideline ":
Recovery from illness: clinical cardinal symptom disappears, secondary disease disappears or substantially disappears, and tongue, arteries and veins recover normal substantially, and colonoscopy shows that intestinal mucosa pathological changes is recovered normal or leaves over cicatrix, and stool routine examination microscopy 3 is subnormal;
Effective: clinical cardinal symptom disappears substantially, secondary disease is improved degree and is reached more than secondary, and tongue, arteries and veins recover normal substantially, and colonoscopy mucosa infection recovery extent reaches more than secondary, and stool routine examination checks that the every high power field of red white corpuscle number is below 3;
Take a turn for the better: clinical cardinal symptom improvement reaches more than one-level, and colonoscopy mucosa infection recovery extent reaches more than one-level, and stool routine examination checks that the every high power field of red white corpuscle number is at about 5;
Invalid: before and after treatment, symptom and colonoscopy are without change.
4.2 results: in 59 routine patients, 26 examples of fully recovering (44.1%), effective 15 examples (25.4%), 12 examples that take a turn for the better (20.3%), invalid 6 examples (10.2%), total effective rate is 89.8%.
5, model case
5.1 Zhao, man, 49 years old, regular stomachache, suffers from diarrhoea, rushes down rear alleviation of pain, and between stage of attack, the many persons of times of defecation can Dagri 6 ~ 10 times, and especially to rise morning as very, matter is rare, accompanies a small amount of mucus, soreness of the waist and knees, whenever tired, improper diet or angry after outbreak.On inspection, diarrhea stool is clearly rare, abdominal swelling, and tongue fur is white and moist, rolling pulse.Take medicine of the present invention, treat 1 course for the treatment of, symptom obviously alleviates, and continues to take 2 courses for the treatment of, recovery from illness, follows up a case by regular visits to without recurrence after half a year.
5.2 Liu, female, 58 years old, abdominal pain diarrhea is very with left lower quadrant, stool day 4 ~ 5 times, matter is rare, desiring defecation constantly, abdominal part bearing down, go to toilet then tenesmus, limbs cold, emaciated physique, oliguria with reddish urine, be off one's feed, fatigue and weakness, left lower quadrant mild tenderness, borborygmus is slightly hyperfunction, tongue fur is white, rolling pulse.Take medicine of the present invention, every day 1 dose, after 2 courses for the treatment of, symptom is clearly better, and continues to take 2 courses for the treatment of, recovery from illness, follows up a case by regular visits to without recurrence after 1 year.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further illustrated, and this embodiment following does not only limit the present invention for illustration of the present invention.
Embodiment 1, a kind of Chinese medicine for the treatment of yang deficiency of spleen and stomache ulcerative colitis is made up of Fructus Viburni Ceanothoidis 30g, Herba Pteridis disparis 20g, Cortex querci dentatae 20g, Fructus Armeniacae Mume 15g, Rhizoma Cimicifugae 15g, Fructus Mahoniae 15g, Potentilla sericea L.(Potentilla poteroides Franch) 15g, Radix Achyranthis 10g, Fructus Tsaoko 10g, Radix Astragali 10g.
Embodiment 2, a kind of Chinese medicine for the treatment of yang deficiency of spleen and stomache ulcerative colitis is made up of Fructus Viburni Ceanothoidis 35g, Herba Pteridis disparis 25g, Cortex querci dentatae 25g, Fructus Armeniacae Mume 20g, Rhizoma Cimicifugae 20g, Fructus Mahoniae 20g, Potentilla sericea L.(Potentilla poteroides Franch) 20g, Radix Achyranthis 15g, Fructus Tsaoko 15g, Radix Astragali 12g.
Embodiment 3, a kind of Chinese medicine for the treatment of yang deficiency of spleen and stomache ulcerative colitis is made up of Fructus Viburni Ceanothoidis 40g, Herba Pteridis disparis 30g, Cortex querci dentatae 30g, Fructus Armeniacae Mume 25g, Rhizoma Cimicifugae 25g, Fructus Mahoniae 25g, Potentilla sericea L.(Potentilla poteroides Franch) 25g, Radix Achyranthis 20g, Fructus Tsaoko 20g, Radix Astragali 15g.
Claims (2)
1. treat a Chinese medicine for yang deficiency of spleen and stomache ulcerative colitis, it is characterized in that it is made up of following raw material medicaments:
Fructus Viburni Ceanothoidis 30-40 part, Herba Pteridis disparis 20-30 part, Cortex querci dentatae 20-30 part, Fructus Armeniacae Mume 15-25 part,
Rhizoma Cimicifugae 15-25 part, Fructus Mahoniae 15-25 part, Potentilla sericea L.(Potentilla poteroides Franch) 15-25 part, Radix Achyranthis 10-20 part,
Fructus Tsaoko 10-20 part, Radix Astragali 10-15 part, its preparation method is that technique makes decoction routinely.
2. Chinese medicine according to claim 1, is characterized in that it is made up of following raw material medicaments:
Fructus Viburni Ceanothoidis 35 parts, Herba Pteridis disparis 25 parts, Cortex querci dentatae 25 parts, Fructus Armeniacae Mume 20 parts,
Rhizoma Cimicifugae 20 parts, Fructus Mahoniae 20 parts, Potentilla sericea L.(Potentilla poteroides Franch) 20 parts, Radix Achyranthis 15 parts,
Fructus Tsaoko 15 parts, the Radix Astragali 12 parts, its preparation method is that technique makes decoction routinely.
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| CN103495031A (en) * | 2013-09-09 | 2014-01-08 | 白石根 | Medicament for treating ulcerative colitis |
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| CN103736000A (en) | 2014-04-23 |
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