CN103476787B - 用于使用浓缩给料分离骨桥蛋白的方法 - Google Patents

用于使用浓缩给料分离骨桥蛋白的方法 Download PDF

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Publication number
CN103476787B
CN103476787B CN201280015375.4A CN201280015375A CN103476787B CN 103476787 B CN103476787 B CN 103476787B CN 201280015375 A CN201280015375 A CN 201280015375A CN 103476787 B CN103476787 B CN 103476787B
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milk
protein
derived
feedstock
range
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Chinese (zh)
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CN103476787A (zh
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汉斯·贝特尔森
彼得·朗堡·魏谢
特赖因·特鲁格瓦森
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Arla Foods AMBA
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23JPROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J1/00Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
    • A23J1/20Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from milk, e.g. casein; from whey
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/18Ion-exchange chromatography
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Peptides Or Proteins (AREA)
  • Dairy Products (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Fodder In General (AREA)
  • Feed For Specific Animals (AREA)
CN201280015375.4A 2011-03-03 2012-03-05 用于使用浓缩给料分离骨桥蛋白的方法 Active CN103476787B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161448775P 2011-03-03 2011-03-03
EP11156826 2011-03-03
US61/448,775 2011-03-03
EP11156826.7 2011-03-03
PCT/EP2012/053749 WO2012117120A1 (en) 2011-03-03 2012-03-05 Method for isolating osteopontin using concentrated feeds

Publications (2)

Publication Number Publication Date
CN103476787A CN103476787A (zh) 2013-12-25
CN103476787B true CN103476787B (zh) 2016-03-09

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CN201280015375.4A Active CN103476787B (zh) 2011-03-03 2012-03-05 用于使用浓缩给料分离骨桥蛋白的方法
CN201510434329.3A Active CN105085649B (zh) 2011-03-03 2012-03-05 使用包含cmp或酪蛋白种类的给料分离骨桥蛋白的方法
CN201280015495.4A Active CN103492408B (zh) 2011-03-03 2012-03-05 使用包含cmp或酪蛋白种类的给料来分离骨桥蛋白的方法

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CN201510434329.3A Active CN105085649B (zh) 2011-03-03 2012-03-05 使用包含cmp或酪蛋白种类的给料分离骨桥蛋白的方法
CN201280015495.4A Active CN103492408B (zh) 2011-03-03 2012-03-05 使用包含cmp或酪蛋白种类的给料来分离骨桥蛋白的方法

Country Status (15)

Country Link
US (2) US9181325B2 (enExample)
EP (2) EP2681231B1 (enExample)
JP (2) JP6012053B2 (enExample)
KR (2) KR101940829B1 (enExample)
CN (3) CN103476787B (enExample)
AR (2) AR088719A1 (enExample)
AU (2) AU2012222312B2 (enExample)
BR (2) BR112013022252B1 (enExample)
CA (2) CA2828746C (enExample)
DK (2) DK2681231T3 (enExample)
EA (2) EA023615B1 (enExample)
ES (2) ES2565380T3 (enExample)
MX (2) MX2013010019A (enExample)
PL (2) PL2681231T3 (enExample)
WO (2) WO2012117120A1 (enExample)

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CN107257152B (zh) * 2011-04-28 2021-04-09 佐尔循环公司 用于更新数据、操作参数和/或软件的系统
EA201491691A1 (ru) 2012-03-28 2015-04-30 Арла Фудз Амба Агрегаты наночастиц, содержащие остеопонтин и кальций- и/или стронцийсодержащие частицы
NZ715430A (en) * 2013-07-05 2022-01-28 Arla Foods Amba Mammalian milk osteopontin for enhancing immune responsiveness
US9661868B2 (en) * 2013-07-16 2017-05-30 Mead Johnson Nutrition Company Expanded bed adsorption methods for isolation of basic milk proteins including lactoferrin
KR200482960Y1 (ko) 2016-04-07 2017-03-21 오숙희 고주파 얼굴 축소 시술기
CN109906040A (zh) * 2016-07-06 2019-06-18 积木营养品有限公司 营养配方食品
US12109284B2 (en) 2016-11-08 2024-10-08 Dentherapy Ltd Compositions comprising fluoride and calcium and method for preparing them
US20200404946A1 (en) * 2017-12-22 2020-12-31 Societe Des Produits Nestle Nestle S.A. Extracts and their use
CN109613140B (zh) * 2019-01-07 2021-10-08 雅士利国际集团有限公司 食品中酪蛋白磷酸肽的检测方法
CA3182755A1 (en) 2020-06-15 2021-12-23 James W. McGrath Jr. Nutritional formula
GB202010987D0 (en) 2020-07-16 2020-09-02 Dentherapy Ltd Oral care compositions and methods
CN117377391A (zh) * 2021-04-19 2024-01-09 雀巢产品有限公司 乳蛋白质级分作为骨桥蛋白源的用途
CN113567573B (zh) * 2021-07-09 2023-06-02 黑龙江飞鹤乳业有限公司 骨桥蛋白的分离方法和分析方法
GB202110114D0 (en) 2021-07-14 2021-08-25 Dentherapy Ltd Oral care compositions for use in treaatment
EP4587455A1 (en) 2022-09-16 2025-07-23 Univerza V Ljubljani Isolation of osteopontin and glycomacropeptide from whey
WO2025008636A1 (en) 2023-07-06 2025-01-09 Dentherapy Ltd Oral care compositions for use in the treatment of dental health conditions
CN117837766A (zh) * 2023-12-27 2024-04-09 美维仕(北京)健康管理有限公司 营养组合物及其应用

Citations (2)

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Publication number Priority date Publication date Assignee Title
WO2001049741A2 (en) * 2000-01-07 2001-07-12 Arla Foods Amba A process for isolation of osteopontin from milk
CN1810292A (zh) * 1998-05-06 2006-08-02 基因技术股份有限公司 用离子交换层析纯化蛋白质

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WO1998014071A1 (en) * 1996-10-01 1998-04-09 John Stephen Ayers Process for isolating glycomacropeptide from dairy products with a phenylalanine impurity of 0.5 %w/w
AU748002B2 (en) 1997-12-31 2002-05-30 Depuy Orthopaedics, Inc. Osteopontin-based compositions for enhancing bone repair
CA2393270A1 (en) * 1999-12-08 2001-06-14 Massey University Process for separation of whey proteins using a novel anion exchanger
NZ507335A (en) 2000-10-05 2004-10-29 New Zealand Dairy Board Bone health compositions derived from milk comprising an acidic protein fraction but that does not contain CGMP

Patent Citations (2)

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CN1810292A (zh) * 1998-05-06 2006-08-02 基因技术股份有限公司 用离子交换层析纯化蛋白质
WO2001049741A2 (en) * 2000-01-07 2001-07-12 Arla Foods Amba A process for isolation of osteopontin from milk

Non-Patent Citations (2)

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Title
A rapid method for purifying osteopontin from bovine milk and interaction between osteopontin and other milk proteins;Azuma N et.al;《 International Dairy Journal》;20060401;第16卷(第4期);370-378 *
Purificaiton and characterization of osteopontin from human milk;SORENSEN S et.al;《PROTEIN EXPRESSION AND PURIFICATION》;20030801;第30卷(第2期);238-239 *

Also Published As

Publication number Publication date
AR085620A1 (es) 2013-10-16
KR101940830B1 (ko) 2019-01-21
EA201391204A1 (ru) 2014-02-28
BR112013022251A2 (pt) 2018-06-12
US20140051831A1 (en) 2014-02-20
EP2681230A1 (en) 2014-01-08
EP2681230B1 (en) 2015-12-16
EA023615B1 (ru) 2016-06-30
BR112013022252B1 (pt) 2020-12-22
KR20140029398A (ko) 2014-03-10
CN103492408A (zh) 2014-01-01
MX2013010017A (es) 2014-08-01
CN103492408B (zh) 2015-07-29
WO2012117119A1 (en) 2012-09-07
US9181325B2 (en) 2015-11-10
ES2565380T3 (es) 2016-04-04
JP6012053B2 (ja) 2016-10-25
AU2012222313B2 (en) 2017-06-15
CN103476787A (zh) 2013-12-25
CA2828669A1 (en) 2012-09-07
EA023367B1 (ru) 2016-05-31
EP2681231B1 (en) 2015-12-16
AU2012222312A1 (en) 2013-09-19
PL2681230T3 (pl) 2016-07-29
MX2013010019A (es) 2014-05-20
HK1217961A1 (zh) 2017-01-27
JP5967665B2 (ja) 2016-08-10
EP2681231A1 (en) 2014-01-08
DK2681231T3 (en) 2016-03-21
EA201391203A1 (ru) 2014-02-28
KR101940829B1 (ko) 2019-01-21
CN105085649B (zh) 2019-08-16
CN105085649A (zh) 2015-11-25
CA2828746C (en) 2019-05-07
BR112013022251B1 (pt) 2020-03-31
US9181316B2 (en) 2015-11-10
JP2014511388A (ja) 2014-05-15
BR112013022252A2 (pt) 2018-06-12
NZ614872A (en) 2015-07-31
CA2828669C (en) 2019-06-04
NZ614874A (en) 2015-07-31
PL2681231T3 (pl) 2016-07-29
AU2012222312B2 (en) 2017-06-08
CA2828746A1 (en) 2012-09-07
KR20140029399A (ko) 2014-03-10
US20140066607A1 (en) 2014-03-06
ES2565379T3 (es) 2016-04-04
DK2681230T3 (en) 2016-03-21
WO2012117120A1 (en) 2012-09-07
AU2012222313A1 (en) 2013-09-19
JP2014508157A (ja) 2014-04-03
AR088719A1 (es) 2014-07-02

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