CN103415293B - 利用多硫酸化多糖的骨髓水肿的治疗 - Google Patents

利用多硫酸化多糖的骨髓水肿的治疗 Download PDF

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Publication number
CN103415293B
CN103415293B CN201280007433.9A CN201280007433A CN103415293B CN 103415293 B CN103415293 B CN 103415293B CN 201280007433 A CN201280007433 A CN 201280007433A CN 103415293 B CN103415293 B CN 103415293B
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CN
China
Prior art keywords
polysulfate
treatment
bone marrow
pentosan
application
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Active
Application number
CN201280007433.9A
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English (en)
Chinese (zh)
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CN103415293A (zh
Inventor
彼得·戈什
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Paradigm Health Sciences Pty Ltd
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Paradigm Health Sciences Pty Ltd
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Priority claimed from AU2011900325A external-priority patent/AU2011900325A0/en
Application filed by Paradigm Health Sciences Pty Ltd filed Critical Paradigm Health Sciences Pty Ltd
Publication of CN103415293A publication Critical patent/CN103415293A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727—Heparin; Heparan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CN201280007433.9A 2011-02-02 2012-02-02 利用多硫酸化多糖的骨髓水肿的治疗 Active CN103415293B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2011900325 2011-02-02
AU2011900325A AU2011900325A0 (en) 2011-02-02 Treatment of bone marrow edema (oedema) with polysulfated polysaccharides
PCT/AU2012/000091 WO2012103588A1 (en) 2011-02-02 2012-02-02 Treatment of bone marrow edema (oedema) with polysulfated polysaccharides

Publications (2)

Publication Number Publication Date
CN103415293A CN103415293A (zh) 2013-11-27
CN103415293B true CN103415293B (zh) 2016-08-10

Family

ID=46602012

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201280007433.9A Active CN103415293B (zh) 2011-02-02 2012-02-02 利用多硫酸化多糖的骨髓水肿的治疗

Country Status (15)

Country Link
US (6) US9101650B2 (enExample)
EP (1) EP2670412B1 (enExample)
JP (1) JP5883458B2 (enExample)
KR (1) KR101840079B1 (enExample)
CN (1) CN103415293B (enExample)
AU (1) AU2012212398B2 (enExample)
CA (1) CA2826166C (enExample)
DK (1) DK2670412T3 (enExample)
ES (1) ES2664611T3 (enExample)
MY (1) MY164728A (enExample)
NO (1) NO2670412T3 (enExample)
PT (1) PT2670412T (enExample)
SG (1) SG192238A1 (enExample)
TW (1) TWI520740B (enExample)
WO (1) WO2012103588A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2014339000B2 (en) * 2013-10-22 2017-05-18 Cell Receptor AG Sulfated polysaccharides for use in the treatment of cancer
EP3661524A4 (en) * 2017-08-04 2021-05-05 Paradigm Biopharmaceuticals Limited TREATMENT OF BONE MARROW DISEASES WITH POLYSULFATED POLYSACCHARIDES
CA3089077A1 (en) 2018-02-16 2019-08-22 Proteobioactives Pty Limited Methods and compositions for the treatment of pain and/or inflammation
EP3758717A4 (en) * 2018-02-28 2021-11-24 Paradigm Biopharmaceuticals Limited TREATMENT OF POST-OPERATIVE JOINT PAIN WITH POLYSULFATED POLYSACCHARIDES
FI3863647T3 (fi) * 2018-10-10 2024-03-01 Paradigm Biopharmaceuticals Ltd Pahanlaatuisen luustokivun hoitaminen pentosaanipolysulfaatilla

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1476328A (zh) * 2000-11-21 2004-02-18 ��������ķ������ 骨质疏松症的治疗

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5668116A (en) 1987-03-19 1997-09-16 Anthropharm Pty. Limited Anti-inflammatory compounds and compositions
US6564083B2 (en) * 2000-12-18 2003-05-13 Hoffmann-La Roche Inc. Bone marrow edema as predictive of susceptibility to developing progressive osteoarthritis
DE10225551A1 (de) * 2002-06-06 2003-12-24 Schering Ag Verwendung von oral verfügbaren Prostacyclinderivaten für die Herstellung eines Arzneimittels zur Behandlung von Krankheiten, die mit Knochenmarködemen assoziiert sind
KR101995016B1 (ko) * 2007-12-04 2019-06-28 프로테오바이오엑티브스 피티와이 엘티디 전구 세포의 보호 및 그의 분화 조절

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1476328A (zh) * 2000-11-21 2004-02-18 ��������ķ������ 骨质疏松症的治疗

Also Published As

Publication number Publication date
AU2012212398A1 (en) 2013-09-19
WO2012103588A1 (en) 2012-08-09
US20140024614A1 (en) 2014-01-23
DK2670412T3 (en) 2018-03-12
CA2826166A1 (en) 2012-08-09
JP2014504613A (ja) 2014-02-24
SG192238A1 (en) 2013-09-30
NO2670412T3 (enExample) 2018-06-02
CN103415293A (zh) 2013-11-27
ES2664611T3 (es) 2018-04-20
AU2012212398B2 (en) 2014-06-05
KR20140012655A (ko) 2014-02-03
US20240156858A1 (en) 2024-05-16
US10610542B2 (en) 2020-04-07
TW201309307A (zh) 2013-03-01
CA2826166C (en) 2017-05-09
US9861657B2 (en) 2018-01-09
US11406660B2 (en) 2022-08-09
US20220362284A1 (en) 2022-11-17
US20150297633A1 (en) 2015-10-22
JP5883458B2 (ja) 2016-03-15
TWI520740B (zh) 2016-02-11
KR101840079B1 (ko) 2018-03-19
US20210015849A1 (en) 2021-01-21
EP2670412A4 (en) 2015-07-08
EP2670412A1 (en) 2013-12-11
US20180021369A1 (en) 2018-01-25
EP2670412B1 (en) 2018-01-03
US9101650B2 (en) 2015-08-11
MY164728A (en) 2018-01-30
PT2670412T (pt) 2018-03-20

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