CN103405729B - Traditional Chinese medicine for treating stationary thyroid-associated ophthalmopathy - Google Patents
Traditional Chinese medicine for treating stationary thyroid-associated ophthalmopathy Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine for treating stationary thyroid-associated ophthalmopathy, which can effectively solve the pharmacy problem for treatment of the stationary thyroid-associated ophthalmopathy. The technical scheme for solving is that the traditional Chinese medicine is prepared from the following crude drugs by weight: 20-30g of eclipta alba, 20-30g of glossy privet fruit, 15-25g of dendrobe, 20-30g of prepared rehmannia root, 20-30g of radix paeoniae alba, 20-30g of motherwort fruit, 15-25g of fruit of Chinese wolfberry, 20-30g of radix scrophulariae, 10-20g of rhizoma sparganii, 10-20g of curcuma zedoary, 10-15g of scorpio, 6-10g of leech, 10-20g of manis pentadactyla, 20-30g of turtle shell, 9-12g of airpotato yam, 20-30g of oyster, 20-30g of thunberg fritillary bulb, 20-30g of semen brassicae, 10-20g of herba lycopi and 20-30g of yellowweed. The traditional Chinese medicine has the effects of eliminating sputum and eliminating dampness, and removing stasis and softening hard mass, is effectively used for treating thyroid-associated ophthalmopathy, is good in curative effect, and safe to dose, and is an innovation in treatment of the thyroid-associated ophthalmopathy on drugs.
Description
Technical field
The present invention relates to medicine, particularly a kind of Chinese medicine for the treatment of thyroid-associated ophthalmopathy resting stage.
Background technology
Thyroid-associated ophthalmopathy (thyroid associated ophthalmopathy, TAO) is one of department of endocrinology common disease, is also to treat one of disease the most difficult in the world at present.The TAO course of disease is longer, and each age group all can occur, multiple with women.The lighter can affect life, work quality, disfigure, and severe one can cause visual deterioration, even blind, brings heavy economy and psychological burden to patient.In recent years, due to living-pattern preservation, the increase of operating pressure, the change of social environment situation, edible iodized salt universal, and the factor such as irregular medication, the sickness rate of TAO obviously rises, and admission rate is high.At present because primary disease reason is not bright, clinical main based on Comprehensive Treatments such as radiation, orbital decompression in hormone, immunosuppressant, growth hormone analogs, antithyroid drug, socket of the eye, but for various reasons, effect is also unsatisfactory, there is no any one medicine up to now and effectively can treat TAO, and obtain long-term remission.Therefore, the medicine of research treatment thyroid-associated ophthalmopathy is technical problem urgently to be resolved hurrily.
Summary of the invention
For above-mentioned situation, for solving the defect of prior art, the object of the present invention is just to provide the Chinese medicine that one treats thyroid-associated ophthalmopathy resting stage (hepatic and renal YIN deficiency, syndrome of intermin-gled phlegm and blood stasis), effectively can solve thyroid-associated ophthalmopathy medicine for treatment resting stage problem.
The technical scheme that the present invention solves is that the traditional Chinese medical science is thought, depression of liver-QI fire-transformation, and refining liquid is expectorant, stasis blocking venation, then consumes impairment of YIN blood for a long time, blocks liver key, and send out as expophthalmos persistent ailment, with the passing of time consuming impairment of YIN essence, is the main cause causing thyroid-associated ophthalmopathy resting stage.Belong to deficiency in origin and excess in superficiality, deficiency and excess holds concurrently miscellaneous diseases card, deficiency in origin is the hepatic and renal YIN deficiency, and mark is real is liver-fire, expectorant coagulates, blood stasis.The hepatic and renal YIN deficiency, phlegm and blood stasis is belonged in resting stage (later stage).Therapeutic Principle should with YIN nourishing improving eyesight, blood circulation promoting and dispersing pathogen accumulation is main, accordingly, Chinese medicine of the present invention adopts the material medicine by following weighing scale: Herba Ecliptae 20-30g, Fructus Ligustri Lucidi 20-30g, Herba Dendrobii 15-25g, Radix Rehmanniae Preparata 20-30g, Radix Paeoniae Alba 20-30g, Fructus Leonuri 20-30g, Fructus Lycii 15-25g, Radix Scrophulariae 20-30g, Rhizoma Sparganii 10-20g, Rhizoma Curcumae 10-20g, Scorpio 10-15g, Hirudo 6-10g, Squama Manis 10-20g, Carapax Trionycis 20-30g, Rhizoma Dioscoreae Bulbiferae 9-12g, Concha Ostreae 20-30g, Bulbus Fritillariae Thunbergii 20-30g, Semen Sinapis Albae 20-30g, Herba Lycopi 10-20g and Herba Senecionis Scandentis 20-30g makes, wherein, above-mentioned raw materials medicament mixed (is put into container) together, add 1000ml water soaking half an hour, intense fire decocts to boiling, use slow fire boiling instead 30 minutes, filter, obtain the first filtrate, for subsequent use, filtering residue adds 800ml water and decocts once again, filters, obtains the second filtrate, the first filtrate and the mixing of the second filtrate is concentrated into 200-300ml, obtains final product.
The pure traditional Chinese medicine of the present invention, there is effect of YIN nourishing improving eyesight, blood circulation promoting and dispersing pathogen accumulation, be effective to the treatment of thyroid-associated ophthalmopathy resting stage (hepatic and renal YIN deficiency, syndrome of intermin-gled phlegm and blood stasis), good effect, drug safety is the innovation on treatment thyroid-associated ophthalmopathy resting stage (hepatic and renal YIN deficiency, syndrome of intermin-gled phlegm and blood stasis) medicine.
Detailed description of the invention
Below in conjunction with embodiment, the specific embodiment of the present invention is described in further detail.
Embodiment 1
This Chinese medicine is by the material medicine of following weighing scale: Herba Ecliptae 20g, Fructus Ligustri Lucidi 20g, Herba Dendrobii 15g, Radix Rehmanniae Preparata 20g, Radix Paeoniae Alba 20g, Fructus Leonuri 20g, Fructus Lycii 15g, Radix Scrophulariae 20g, Rhizoma Sparganii 10g, Rhizoma Curcumae 10g, Scorpio 10g, Hirudo 6g, Squama Manis 10g, Carapax Trionycis 20g, Rhizoma Dioscoreae Bulbiferae 9g, Concha Ostreae 20g, Bulbus Fritillariae Thunbergii 20g, Semen Sinapis Albae 20g, Herba Lycopi 10g and Herba Senecionis Scandentis 20g makes, wherein, by above-mentioned raw materials medicament mixed together, put into medicine pot, add 1000ml water soaking half an hour, intense fire decocts to boiling, use slow fire boiling instead 30 minutes, filter, obtain the first filtrate, for subsequent use, filtering residue adds 800ml water and decocts once again, filters, obtains the second filtrate, the first filtrate and the mixing of the second filtrate is concentrated into 200ml, obtains final product.
Embodiment 2
This Chinese medicine is by the material medicine of following weighing scale: Herba Ecliptae 25g, Fructus Ligustri Lucidi 25g, Herba Dendrobii 20g, Radix Rehmanniae Preparata 25g, Radix Paeoniae Alba 25g, Fructus Leonuri 25g, Fructus Lycii 20g, Radix Scrophulariae 25g, Rhizoma Sparganii 15g, Rhizoma Curcumae 15g, Scorpio 12g, Hirudo 8g, Squama Manis 15g, Carapax Trionycis 25g, Rhizoma Dioscoreae Bulbiferae 10g, Concha Ostreae 25g, Bulbus Fritillariae Thunbergii 25g, Semen Sinapis Albae 25g, Herba Lycopi 15g and Herba Senecionis Scandentis 25g makes, wherein, by above-mentioned raw materials medicament mixed together, put into medicine pot, add 1000ml water soaking half an hour, intense fire decocts to boiling, use slow fire boiling instead 30 minutes, filter, obtain the first filtrate, for subsequent use, filtering residue adds 800ml water and decocts once again, filters, obtains the second filtrate, the first filtrate and the mixing of the second filtrate is concentrated into 250ml, obtains final product.
Embodiment 3
This Chinese medicine is by the material medicine of following weighing scale: Herba Ecliptae 30g, Fructus Ligustri Lucidi 30g, Herba Dendrobii 25g, Radix Rehmanniae Preparata 30g, Radix Paeoniae Alba 30g, Fructus Leonuri 30g, Fructus Lycii 25g, Radix Scrophulariae 30g, Rhizoma Sparganii 20g, Rhizoma Curcumae 20g, Scorpio 15g, Hirudo 10g, Squama Manis 20g, Carapax Trionycis 30g, Rhizoma Dioscoreae Bulbiferae 12g, Concha Ostreae 30g, Bulbus Fritillariae Thunbergii 30g, Semen Sinapis Albae 30g, Herba Lycopi 20g and Herba Senecionis Scandentis 30g makes, wherein, by above-mentioned raw materials medicament mixed together, put into medicine pot, add 1000ml water soaking half an hour, intense fire decocts to boiling, use slow fire boiling instead 30 minutes, filter, obtain the first filtrate, for subsequent use, filtering residue adds 800ml water and decocts once again, filters, obtains the second filtrate, the first filtrate and the mixing of the second filtrate is concentrated into 300ml, obtains final product.
Embodiment 4
This Chinese medicine is by the material medicine of following weighing scale: Herba Ecliptae 20-25g, Fructus Ligustri Lucidi 20-25g, Herba Dendrobii 15-20g, Radix Rehmanniae Preparata 20-25g, Radix Paeoniae Alba 20-25g, Fructus Leonuri 20-25g, Fructus Lycii 15-20g, Radix Scrophulariae 20-25g, Rhizoma Sparganii 10-15g, Rhizoma Curcumae 10-15g, Scorpio 10-12g, Hirudo 6-8g, Squama Manis 10-15g, Carapax Trionycis 20-25g, Rhizoma Dioscoreae Bulbiferae 9-10g, Concha Ostreae 20-25g, Bulbus Fritillariae Thunbergii 20-25g, Semen Sinapis Albae 20-25g, Herba Lycopi 10-15g and Herba Senecionis Scandentis 20-25g makes, wherein, by above-mentioned raw materials medicament mixed together, put into medicine pot, add 1000ml water soaking half an hour, intense fire decocts to boiling, use slow fire boiling instead 30 minutes, filter, obtain the first filtrate, for subsequent use, filtering residue adds 800ml water and decocts once again, filters, obtains the second filtrate, the first filtrate and the mixing of the second filtrate is concentrated into 200-250ml, obtains final product.
Embodiment 5
This Chinese medicine is by the material medicine of following weighing scale: Herba Ecliptae 26-30g, Fructus Ligustri Lucidi 26-30g, Herba Dendrobii 21-25g, Radix Rehmanniae Preparata 26-30g, Radix Paeoniae Alba 26-30g, Fructus Leonuri 26-30g, Fructus Lycii 21-25g, Radix Scrophulariae 26-30g, Rhizoma Sparganii 16-20g, Rhizoma Curcumae 16-20g, Scorpio 13-15g, Hirudo 9-10g, Squama Manis 16-20g, Carapax Trionycis 26-30g, Rhizoma Dioscoreae Bulbiferae 11-12g, Concha Ostreae 26-30g, Bulbus Fritillariae Thunbergii 26-30g, Semen Sinapis Albae 26-30g, Herba Lycopi 16-20g and Herba Senecionis Scandentis 26-30g makes, wherein, by above-mentioned raw materials medicament mixed together, put into medicine pot, add 1000ml water soaking half an hour, intense fire decocts to boiling, use slow fire boiling instead 30 minutes, filter, obtain the first filtrate, for subsequent use, filtering residue adds 800ml water and decocts once again, filters, obtains the second filtrate, the first filtrate and the mixing of the second filtrate is concentrated into 260-300ml, obtains final product.
In said components, wherein:
Herba Ecliptae: nourishing the liver and kidney, cooling blood for hemostasis.For syndrome of yin deficiency of liver and kidney; The card of losing blood of YinXuXueRe.
Fructus Ligustri Lucidi: nourishing the liver and kidney, crow must improving eyesight.For syndrome of yin deficiency of liver and kidney.
Radix Rehmanniae Preparata: yin nourishing of enriching blood, life essence-filling, marrow-benefitting.For all cards of blood deficiency; The all cards of the hepatic and renal YIN deficiency.
The Radix Paeoniae Alba: nourish blood yin fluid astringing, easing the affected liver to relieve pain, suppressing liver-YANG.For liver-blood deficiency, menoxenia; Incoordination between the liver and spleen, breast side of body epigastric pain, the anxious pain of extremity contraction; Excessive rising of liver-YANG, has a headache dizzy.
Fructus Leonuri: promoting blood flow to regulate menstruation, liver heat removing and eyesight improving.For menoxenia, amenorrhea, dysmenorrhea, cataract, dizzy distending pain.
Herba Dendrobii: reinforcing stomach reg fluid, nourishing YIN and clearing away heat.For syndrome of deficiency of stomach yin, consumption of body fluid caused by febrile disease is demonstrate,proved; Syndrome of deficiency of kidney yin.
Fructus Lycii: nourishing the liver and kidney, replenishing vital essence to improve eyesight.For the hepatic and renal YIN deficiency and senilism card.
Radix Scrophulariae: clearing away heat and cooling blood, eliminating fire and detoxication, YIN nourishing.Join the army for pathogenic warmth, cave in pericardium, maculae caused by violent heat pathogen; Consumption of YIN caused by febrile disease, constipation is hindered in Tianjin, hectic fever due to YIN-deficiency chronic cough; Conjunctival congestion pharyngalgia, scrofula, diphtheria, carbuncle sore tumefacting virus.
Rhizoma Sparganii: removing blood stasis circulation of qi promoting, removing food stagnancy pain relieving.Yong Yu lumps in the chest and abdomen, amenorrhea, trusted subordinate's stasis of blood pain; Food stagnation abdominal distention.
Rhizoma Curcumae: removing blood stasis circulation of qi promoting, removing food stagnancy pain relieving.Yong Yu lumps in the chest and abdomen, amenorrhea, trusted subordinate's stasis of blood pain; Food stagnation abdominal distention.
Scorpio: endogenous wind stopping relieving convulsion, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain effect.Spasm is twitched, sore swollen toxin sucutaneous nodule scrofula, rheumatoid arthritis stubborn, intractable migraine and general headache.
Hirudo: removing blood stasis, stimulates the menstrual flow, and for blood-retention, lump in the abdomen, gathers, women's amenorrhea, and blood stasis becomes consumptive disease, injury from falling down, and order is pain also, nebula.
Squama Manis: invigorate blood circulation Xiao Disorder, stimulating milk secretion of stimulating the menstrual flow, detumescence and apocenosis.Yong Yu mass in the abdomen, amenorrhea; Rheumatic arthralgia, paralysis due to windstroke; Lack of lactation after delivery; Carbuncle sore tumefacting virus, scrofula.
Carapax Trionycis: nourishing YIN for suppressing the hyperactive YANG, brings down a fever except steaming, hard masses softening and resolving.For syndrome of yin deficiency of liver and kidney; Lumps in the chest and abdomen.
Rhizoma Dioscoreae Bulbiferae: dissipating phlegm and resolving masses disappears wart, heat-clearing and toxic substances removing.For goiter, sore swollen toxin, laryngopharynx swelling and pain, venom.
Concha Ostreae: tranquillization with heavy prescription, suppressing the hyperactive liver and subsiding YANG, hard masses softening and resolving, restrains astringent or styptic treatment for spontaneous sweating.For irritability, palpitation with fear insomnia; Excessive rising of liver-YANG, has a dizzy spell; Sucutaneous nodule, scrofula, goiter ， lumps in the chest and abdomen; The all cards of slippage.
Bulbus Fritillariae Thunbergii: removing heat-phlegm, eliminating stagnation eliminating carbuncle.For wind heat, phlegm-heat cough; Scrofula, goiter, acute mastitis sore, lung abscess.
Semen Sinapis Albae: warming the lung for resolving phlegm, promoting the circulation of QI eliminating stagnation, removing obstruction in the collateral to relieve pain.Breath with cough for cold-phlegm, hydrothorax; Carbuncle of yin nature multiple abscess, numb limbs and tense tendons, arthralgia.
Herba Lycopi: promoting blood flow to regulate menstruation, inducing diuresis to remove edema.For blood stasis amenorrhea, dysmenorrhea, the stagnant stomachache of the stasis of blood in puerperal; Traumatic injury, pain caused by ecchymoma, sore and toxic; Edema, ascites.
Herba Senecionis Scandentis: heat-clearing and toxic substances removing, liver heat removing and eyesight improving.For carbuncle sore tumefacting virus; Conjunctival congestion and swelling pain; Damp-heat dysentery.
Above-mentioned component, through science, reasonable compatibility, is supported mutually, has effect of YIN nourishing improving eyesight, blood circulation promoting and dispersing pathogen accumulation, is effective to the treatment of thyroid-associated ophthalmopathy resting stage, good effect, drug safety, and obtains sufficient proof through clinical data, and pertinent clinical data is as follows:
(1), the inclusion criteria of Patients with Thyroid Associated Ophthalmopathy:
All cases is all selected by American Thyroid Association (ATA) thyroid-associated ophthalmopathy in 1977 diagnostic criteria.Companion or without abnormal thyroid function.Gestation, women breast-feeding their children, abnormal liver function person; Be associated with the severe primary diseases such as cardiovascular, liver, kidney and hemopoietic system, psychotic; Perforation of cornea, conjunctivitis, keratitis, myasthenia gravis, intracranial and retrobulbar tumor person; Accept other Chinese medicines, glucocorticoid and other immunosuppressant treatment person; Participate in except other drug clinical trial person in nearly March.
(2), the diagnostic criteria of thyroid-associated ophthalmopathy:
TAO diagnostic criteria was with reference to American Thyroid Association (ATA) the NOSPECS standard of recommending in 1977.This standard initial connects together and can be summarized in " NO SPECS ".This standard is divided into 0-6 level according to the order of severity of oculopathy, is divided into again 0 again, a, b, c different brackets in every one-level of 2-6 level.Wherein 0-1 level is non-infiltration exophthalmos, and 2-6 level is infiltrative exophthalmos.N is the sings and symptoms without oculopathy; 0 for only having the sign such as eyelid contracture, upper eyelid Chi Luo and asymptomatic; S is that soft tissue is got involved, there is photophobia, shed tears, pain, foreign body sensation, conjunctival congestion edema etc.; P is exophthalmos; E is that extraocular muscles is got involved, and ocular movemeut is limited, occurs diplopia; C is corneal involvement, damage or ulcer; S is that optic nerve is got involved, and wild defect, visual deterioration look visual deterioration, optic nerve lesion.
(3), efficacy assessment standard:
effective: NOSPECS classification expophthalmos degree change>=2 mm or diplopia disappearance person; Or within expophthalmos degree 16mm, without conjunctival congestion, blepharoedema, diplopia disappearance person; Or CAS score value reduces to be greater than 3 points of persons after treatment;
effectively: often fall one-level in NOSPECS classification or in same one-level, alleviate once above person; Expophthalmos retraction >2mm person is for taking a turn for the better; CAS score value 1 ~ 3 point of person after treatment;
invalid: the unchanged person of NOSPECS classification; Expophthalmos retraction <2mm or add severe one; After treatment, CAS score value is less than 1 point of person.
(4), therapeutic scheme:
To the patient being diagnosed as thyroid-associated ophthalmopathy resting stage (hepatic and renal YIN deficiency, syndrome of intermin-gled phlegm and blood stasis), treat, when taking with Chinese medicine of the present invention, sooner or later respectively once, each 100-150ml, two hours after meal decoction being taken warmly, within 15 days, be a course for the treatment of, after 4 courses for the treatment of, add up curative effect.
(5), statistical procedures:
Selected thyroid-associated ophthalmopathy resting stage (hepatic and renal YIN deficiency, syndrome of intermin-gled phlegm and blood stasis) patient is totally 45 examples, wherein man 14 example, female 31 example, the age be (43.2 ± 9.6) year.By above-mentioned (four) therapeutic scheme, the Chinese medicine that oral the present invention provides, add up after 6 courses for the treatment of, clinical effective 10 examples, effective 28, total effective rate reaches 84.4%, show this invention treatment by Chinese herbs thyroid-associated ophthalmopathy resting stage (hepatic and renal YIN deficiency, syndrome of intermin-gled phlegm and blood stasis) Be very effective, reach clinical treatment object, and over the course for the treatment of, have no obvious adverse reaction.
Model case:
Case 1: Shen, female, 34 years old, hyperthyroidism medical history 5 years half, non-regular treatment.Engender that eyes are given prominence to nearly April, dry and astringent, visual deterioration, ocular movemeut is limited, and friction sense is obvious, diplopia, retraction of upper eyelid, hypophasis, in serum, FT3, FT4 level raises, and TSH level declines, CT examination finds that superior rectus is loose, NOSPECS classification 4 grades, eyes expophthalmos degree 20mm, meets thyroid-associated ophthalmopathy.After taking 6 courses for the treatment of of this Chinese medicine, patient's above-mentioned symptom alleviates gradually, NOSPECS classification 3 grades, eyes expophthalmos degree 19mm.
Case 2: Ji, female, 48 years old, is diagnosed as hyperthyroidism and merges thyroid-associated ophthalmopathy 4 years, rule of taking medicine.Present eyes are given prominence to gradually, eyes dysraphism, and obviously, dry and astringent, in serum, FT3, FT4, TSH level is normal for foreign body sensation, friction sense, and MRI checks and finds that lateral rectus is loose, and NOSPECS classification 4 grades, meets thyroid-associated ophthalmopathy.After taking 6 courses for the treatment of of this Chinese medicine, patient's above-mentioned symptom alleviates gradually, NOSPECS classification 2 grades.
Case 3: week certain, man, 39 years old, previously has chronic lymphocytic thyroiditis's history.Engender that double eyeball is given prominence to nearly March, diplopia, dry and astringent, visual deterioration, retraction of upper eyelid, eyes are converge like the spokes of a wheel at the hub bad, and in serum, FT3, FT4 level is normal, and TSH level increases, MRI shows inferior retcus and increases thick, and NOSPECS classification 4 grades, eyes expophthalmos degree 21mm, meets thyroid-associated ophthalmopathy.After taking 6 courses for the treatment of of this Chinese medicine, patient's above-mentioned symptom alleviates gradually.NOSPECS classification 3 grades, left eye expophthalmos degree 20mm, right eye expophthalmos degree 19mm.
Case 4: Zheng, female, 53 years old, hyperthyroidism 10 years, rule was taken medicine after drug withdrawal 3 times and is all recurred.This time drug withdrawal later six months, engender that double eyeball is given prominence to, diplopia, dry and astringent, have foreign body sensation, visual deterioration, hypophasis, in serum, FT3, FT4 level, TSH level are in normal range.MRI shows many eye muscle and increases thick, NOSPECS classification 4 grades, left eye expophthalmos degree 22mm, right eye expophthalmos degree 21mm.Meet thyroid-associated ophthalmopathy.After taking 8 courses for the treatment of of this Chinese medicine, patient's above-mentioned symptom alleviates gradually, NOSPECS classification 3 grades, eyes expophthalmos degree 20mm.
Case 5: time, female, 30 years old, hyperthyroidism medical history 8 years, rule was taken medicine drug withdrawal 1 year.Nearly February engenders exophthalmos, and eyes are dry and astringent, and secretions reduces, visual deterioration, friction sense obviously, time have pain, diplopia, MRI shows superior rectus, inferior retcus, medial rectus increasing slightly, in serum, FT3, FT4 level raises, and TSH level declines, NOSPECS classification 4 grades, expophthalmos degree 21mm, meets thyroid-associated ophthalmopathy.After taking 6 courses for the treatment of of this Chinese medicine, patient's above-mentioned symptom alleviates gradually, after continuing to take 6 courses for the treatment of of this Chinese medicine, and NOSPECS classification 3 grades, eyes expophthalmos degree 20mm.
(6), conclusion
Shown by above-mentioned situation, the present invention is the active drug being used for the treatment of thyroid-associated ophthalmopathy resting stage (hepatic and renal YIN deficiency, syndrome of intermin-gled phlegm and blood stasis), can obvious relief of symptoms, improve symptom, improve patients ' life quality, effective percentage reaches more than 84%, have no side effect, stable curative effect, safe and reliable, there is actual clinical meaning.
Claims (6)
1. treat the Chinese medicine of thyroid-associated ophthalmopathy resting stage for one kind, it is characterized in that, this Chinese medicine is by the material medicine of following weighing scale: Herba Ecliptae 20-30g, Fructus Ligustri Lucidi 20-30g, Herba Dendrobii 15-25g, Radix Rehmanniae Preparata 20-30g, Radix Paeoniae Alba 20-30g, Fructus Leonuri 20-30g, Fructus Lycii 15-25g, Radix Scrophulariae 20-30g, Rhizoma Sparganii 10-20g, Rhizoma Curcumae 10-20g, Scorpio 10-15g, Hirudo 6-10g, Squama Manis 10-20g, Carapax Trionycis 20-30g, Rhizoma Dioscoreae Bulbiferae 9-12g, Concha Ostreae 20-30g, Bulbus Fritillariae Thunbergii 20-30g, Semen Sinapis Albae 20-30g, Herba Lycopi 10-20g and Herba Senecionis Scandentis 20-30g makes, wherein, by above-mentioned raw materials medicament mixed together, add 1000ml water soaking half an hour, intense fire decocts to boiling, use slow fire boiling instead 30 minutes, filter, obtain the first filtrate, for subsequent use, filtering residue adds 800ml water and decocts once again, filters, obtains the second filtrate, the first filtrate and the mixing of the second filtrate is concentrated into 200-300ml, obtains final product.
2. the Chinese medicine for the treatment of thyroid-associated ophthalmopathy according to claim 1 resting stage, it is characterized in that, this Chinese medicine is by the material medicine of following weighing scale: Herba Ecliptae 20g, Fructus Ligustri Lucidi 20g, Herba Dendrobii 15g, Radix Rehmanniae Preparata 20g, Radix Paeoniae Alba 20g, Fructus Leonuri 20g, Fructus Lycii 15g, Radix Scrophulariae 20g, Rhizoma Sparganii 10g, Rhizoma Curcumae 10g, Scorpio 10g, Hirudo 6g, Squama Manis 10g, Carapax Trionycis 20g, Rhizoma Dioscoreae Bulbiferae 9g, Concha Ostreae 20g, Bulbus Fritillariae Thunbergii 20g, Semen Sinapis Albae 20g, Herba Lycopi 10g and Herba Senecionis Scandentis 20g makes, wherein, by above-mentioned raw materials medicament mixed together, put into medicine pot, add 1000ml water soaking half an hour, intense fire decocts to boiling, use slow fire boiling instead 30 minutes, filter, obtain the first filtrate, for subsequent use, filtering residue adds 800ml water and decocts once again, filters, obtains the second filtrate, the first filtrate and the mixing of the second filtrate is concentrated into 200ml, obtains final product.
3. the Chinese medicine for the treatment of thyroid-associated ophthalmopathy according to claim 1 resting stage, its spy is, this Chinese medicine is by the material medicine of following weighing scale: Herba Ecliptae 25g, Fructus Ligustri Lucidi 25g, Herba Dendrobii 20g, Radix Rehmanniae Preparata 25g, Radix Paeoniae Alba 25g, Fructus Leonuri 25g, Fructus Lycii 20g, Radix Scrophulariae 25g, Rhizoma Sparganii 15g, Rhizoma Curcumae 15g, Scorpio 12g, Hirudo 8g, Squama Manis 15g, Carapax Trionycis 25g, Rhizoma Dioscoreae Bulbiferae 10g, Concha Ostreae 25g, Bulbus Fritillariae Thunbergii 25g, Semen Sinapis Albae 25g, Herba Lycopi 15g and Herba Senecionis Scandentis 25g makes, wherein, by above-mentioned raw materials medicament mixed together, put into medicine pot, add 1000ml water soaking half an hour, intense fire decocts to boiling, use slow fire boiling instead 30 minutes, filter, obtain the first filtrate, for subsequent use, filtering residue adds 800ml water and decocts once again, filters, obtains the second filtrate, the first filtrate and the mixing of the second filtrate is concentrated into 250ml, obtains final product.
4. the Chinese medicine for the treatment of thyroid-associated ophthalmopathy according to claim 1 resting stage, it is characterized in that, this Chinese medicine is by the material medicine of following weighing scale: Herba Ecliptae 30g, Fructus Ligustri Lucidi 30g, Herba Dendrobii 25g, Radix Rehmanniae Preparata 30g, Radix Paeoniae Alba 30g, Fructus Leonuri 30g, Fructus Lycii 25g, Radix Scrophulariae 30g, Rhizoma Sparganii 20g, Rhizoma Curcumae 20g, Scorpio 15g, Hirudo 10g, Squama Manis 20g, Carapax Trionycis 30g, Rhizoma Dioscoreae Bulbiferae 12g, Concha Ostreae 30g, Bulbus Fritillariae Thunbergii 30g, Semen Sinapis Albae 30g, Herba Lycopi 20g and Herba Senecionis Scandentis 30g makes, wherein, by above-mentioned raw materials medicament mixed together, put into medicine pot, add 1000ml water soaking half an hour, intense fire decocts to boiling, use slow fire boiling instead 30 minutes, filter, obtain the first filtrate, for subsequent use, filtering residue adds 800ml water and decocts once again, filters, obtains the second filtrate, the first filtrate and the mixing of the second filtrate is concentrated into 300ml, obtains final product.
5. the Chinese medicine for the treatment of thyroid-associated ophthalmopathy according to claim 1 resting stage, it is characterized in that, this Chinese medicine is by the material medicine of following weighing scale: Herba Ecliptae 20-25g, Fructus Ligustri Lucidi 20-25g, Herba Dendrobii 15-20g, Radix Rehmanniae Preparata 20-25g, Radix Paeoniae Alba 20-25g, Fructus Leonuri 20-25g, Fructus Lycii 15-20g, Radix Scrophulariae 20-25g, Rhizoma Sparganii 10-15g, Rhizoma Curcumae 10-15g, Scorpio 10-12g, Hirudo 6-8g, Squama Manis 10-15g, Carapax Trionycis 20-25g, Rhizoma Dioscoreae Bulbiferae 9-10g, Concha Ostreae 20-25g, Bulbus Fritillariae Thunbergii 20-25g, Semen Sinapis Albae 20-25g, Herba Lycopi 10-15g and Herba Senecionis Scandentis 20-25g makes, wherein, by above-mentioned raw materials medicament mixed together, put into medicine pot, add 1000ml water soaking half an hour, intense fire decocts to boiling, use slow fire boiling instead 30 minutes, filter, obtain the first filtrate, for subsequent use, filtering residue adds 800ml water and decocts once again, filters, obtains the second filtrate, the first filtrate and the mixing of the second filtrate is concentrated into 200-250ml, obtains final product.
6. the Chinese medicine for the treatment of thyroid-associated ophthalmopathy according to claim 1 resting stage, it is characterized in that, this Chinese medicine is by the material medicine of following weighing scale: Herba Ecliptae 26-30g, Fructus Ligustri Lucidi 26-30g, Herba Dendrobii 21-25g, Radix Rehmanniae Preparata 26-30g, Radix Paeoniae Alba 26-30g, Fructus Leonuri 26-30g, Fructus Lycii 21-25g, Radix Scrophulariae 26-30g, Rhizoma Sparganii 16-20g, Rhizoma Curcumae 16-20g, Scorpio 13-15g, Hirudo 9-10g, Squama Manis 16-20g, Carapax Trionycis 26-30g, Rhizoma Dioscoreae Bulbiferae 11-12g, Concha Ostreae 26-30g, Bulbus Fritillariae Thunbergii 26-30g, Semen Sinapis Albae 26-30g, Herba Lycopi 16-20g and Herba Senecionis Scandentis 26-30g makes, wherein, by above-mentioned raw materials medicament mixed together, put into medicine pot, add 1000ml water soaking half an hour, intense fire decocts to boiling, use slow fire boiling instead 30 minutes, filter, obtain the first filtrate, for subsequent use, filtering residue adds 800ml water and decocts once again, filters, obtains the second filtrate, the first filtrate and the mixing of the second filtrate is concentrated into 260-300ml, obtains final product.
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| CN110123518A (en) * | 2017-08-30 | 2019-08-16 | 徐州蓝湖信息科技有限公司 | A kind of medical Exophthalmos eye-care device medical fluid |
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| CN1562262A (en) * | 2004-03-29 | 2005-01-12 | 李爱英 | Chinese herbal medicine for curing hyperthyroidism |
| CN101028440A (en) * | 2007-04-04 | 2007-09-05 | 周世庆 | Oral Chinese-medicinal composition for treating hyperthyroidism |
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| CN1562262A (en) * | 2004-03-29 | 2005-01-12 | 李爱英 | Chinese herbal medicine for curing hyperthyroidism |
| CN101028440A (en) * | 2007-04-04 | 2007-09-05 | 周世庆 | Oral Chinese-medicinal composition for treating hyperthyroidism |
| CN101152511A (en) * | 2007-09-17 | 2008-04-02 | 李广欣 | Medicament for treating hyperthyroidism disease and method of preparing the same |
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