CN103393976B - Chinese medicinal preparation for treating diabetes - Google Patents
Chinese medicinal preparation for treating diabetes Download PDFInfo
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Abstract
The invention discloses a Chinese medicinal preparation for treating diabetes, belonging to the field of medicines. The raw materials of active ingredients of the Chinese medicinal preparation consist of rhizome of Chinese asystasiella, yam, fruit of Thatch screwpine, litsea glutinosa, aralia chinensis, herb of rose glorybind, Chinese ladiestresses root, spirulina platensis, herb of Chinese mesona, leaf of cluster mallow, purple hypoestes herb, running mallow root, rhizome of whorledleaf solomonseal, stem and leaf of hedge glorybind, yew and herb of rough melic. The Chinese medicinal preparation has the effects of reinforcing qi, nourishing yin, promoting secretion of salvia or body fluid, clearing heat and lowering blood sugar, has an obvious treatment effect on phenomena of deficiency of vital qi such as lack of energy, tiredness, puffiness, weakness, or weight loss, thick tongue or teeth mark, is prepared from pure traditional Chinese medicines, has low toxic or side effect, can be used for treating both symptoms and root causes, can effectively control the blood sugar and the urine sugar to restore the functions such as strength and energy, has a certain recovery effect on pancreatic tissue damage, and has the characteristics of obvious curative effect, no relapse after cure, low cost, safety and stability.
Description
Affiliated technical field
The present invention relates to the field of Chinese medicines, relate in particular to a kind of Chinese medicine preparation for the treatment of diabetes.
Background technology
Along with urbanization process acceleration in recent years, China's diabetics constantly increases, and PD speed is difficult to control.Most of type Ⅰ diabetes mellitus patient build obesities, obesity is another factor of induced Diabetic, Insulin receptor INSR decreased number on adipocyte plasma membrane and muscle cell membrane when fat, affinity reduction, somatic cell to insulin decline to the sensitivity of insulin, what cause sugar utilizes obstacle, makes blood sugar increasing and occurs diabetes.In part of diabetes mellitus patient, clearly have inherited genetic factors impact morbidity, for example there are diabetes in an example in twins, and another example has 50% chance morbidity, as is enzygotic twins, many morbidities at the same time.According to statistics, if father or female non-insulin dependent diabetes of suffering from, the risk of children's morbidity is about 10-50%, and as father and mother all suffer from dependent diabetes, children's morbidity risk is higher.Infect and in the predisposing factors of diabetes, account for the main predisposing factors that very important position, particularly viral infection are type Ⅰ diabetes mellitus.In zooscopy, find much virus to cause insulitis and cause a disease, comprise encephalitis, myocarditis virus, Coxsackievirus B 4 etc., viral infection can cause insulitis, causes hypoinsulinism and produces diabetes.The diabetes that in addition, also can make after viral infection to hide increase the weight of and become overt diabetes.
Diabetes are because the regulating power of blood glucose value weakens, blood glucose value raises the generalized metabolic disorder causing extremely, diabetes are characterised in that not only can cause the serious Developmental and Metabolic Disorder such as hyperosmolar coma and ketoacidosis, and because the complication of blood capillary characteristic of disease makes prognosis variation, extremely declined quality of life.Diabetes are roughly divided into the type 2 diabetes mellitus of enhancing and the low stack of insulin secretion of the type 1 diabetes that causes because pancreatic beta cell is destroyed and the resistance to insulin.In diabetes, the insulin secretion in pancreatic beta cell low and cause the low of insulin action superposeing in varying degrees as the insulin resistance in the skeletal muscle of the target cell of insulin etc., thus cause hyperglycemia state.In addition, due to continuing of insulin resistance, form the further such vicious cycle of decline of pancreatic beta cell fatigue, insulin secretion ability, symptom constantly worsens.
At present, the medicament categories for the treatment of diabetes is various, large multi-component complex, and preparation technology's difficulty is large, and although all have certain curative effect, therapeutic effect is not thorough, be easy to recurrence, and therapeutic domain is narrow after healing, and medicine time is long, and relative cost expense is high.
Summary of the invention
The invention provides a kind of Chinese medicine preparation for the treatment of diabetes, there is supplementing QI and nourishing YIN, replenishing body fluid and clearing away heat pathogen, reduce effect of blood glucose, be made up of pure Chinese medicine, toxic and side effects is little, treating both the principal and secondary aspects of a disease, can effectively control blood glucose, glucose in urine, the function such as energy, muscle power is restored, to pancreatic tissue, damage has certain repair, have evident in efficacy, non-relapse after healing, with low cost, the feature of safety and stability.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat a Chinese medicine preparation for diabetes, raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
30～65 parts, 34～70 parts of purling withered trees of 35～70 parts of Fructus Pandani tectoriis of 40～75 portions of Rhizoma Dioscoreaes of Rhizoma seu herba Asystasiellae Chinensis
20～51 parts of 22～55 parts of spirulinas of 25～60 parts of Radix seu Herba Spiranthis Lanceae of 26～63 parts of Herba Calystegiae Japonicae of Cortex araliae chinensis
15～40 parts of 15～45 parts of Radix Malvae rotundifoliaes of 18～46 portions of Herba Hypoestis purpureaes of 20～50 parts of Semen Abutili of Herba mesonae chinensis
10～20 parts of 10～30 parts of Herba Melicae Scabrosaes of 13～33 parts of Ramulus et folium taxi cuspidataes of 13～35 parts of Caulis et Folium Calystegiae sepii of Rhizoma Polygonati Verticillati.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
40～60 parts, 36～65 parts of purling withered trees of 40～66 parts of Fructus Pandani tectoriis of 45～70 portions of Rhizoma Dioscoreaes of Rhizoma seu herba Asystasiellae Chinensis
24～48 parts of 25～53 parts of spirulinas of 30～55 parts of Radix seu Herba Spiranthis Lanceae of 35～60 parts of Herba Calystegiae Japonicae of Cortex araliae chinensis
18～35 parts of 18～40 parts of Radix Malvae rotundifoliaes of 20～43 portions of Herba Hypoestis purpureaes of 22～45 parts of Semen Abutili of Herba mesonae chinensis
12～18 parts of 13～20 parts of Herba Melicae Scabrosaes of 15～30 parts of Ramulus et folium taxi cuspidataes of 16～32 parts of Caulis et Folium Calystegiae sepii of Rhizoma Polygonati Verticillati.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
45～55 parts, 48～60 parts of purling withered trees of 50～60 parts of Fructus Pandani tectoriis of 55～65 portions of Rhizoma Dioscoreaes of Rhizoma seu herba Asystasiellae Chinensis
30～45 parts of 32～50 parts of spirulinas of 35～51 parts of Radix seu Herba Spiranthis Lanceae of 40～55 parts of Herba Calystegiae Japonicae of Cortex araliae chinensis
22～31 parts of 23～35 parts of Radix Malvae rotundifoliaes of 25～40 portions of Herba Hypoestis purpureaes of 26～41 parts of Semen Abutili of Herba mesonae chinensis
14～16 parts of 15～18 parts of Herba Melicae Scabrosaes of 18～25 parts of Ramulus et folium taxi cuspidataes of 20～30 parts of Caulis et Folium Calystegiae sepii of Rhizoma Polygonati Verticillati.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
50 parts, 54 parts of purling withered trees of 55 parts of Fructus Pandani tectoriis of 60 portions of Rhizoma Dioscoreaes of Rhizoma seu herba Asystasiellae Chinensis
37 parts of 40 parts of spirulinas of 43 parts of Radix seu Herba Spiranthis Lanceae of 48 parts of Herba Calystegiae Japonicae of Cortex araliae chinensis
27 parts of 29 parts of Radix Malvae rotundifoliaes of 32 portions of Herba Hypoestis purpureaes of 34 parts of Semen Abutili of Herba mesonae chinensis
15 parts of 16 parts of Herba Melicae Scabrosaes of 21 parts of Ramulus et folium taxi cuspidataes of 25 parts of Caulis et Folium Calystegiae sepii of Rhizoma Polygonati Verticillati.
A preparation method for the treatment of the Chinese medicine preparation of diabetes, is characterized in that: comprise following processing step:
(1) Rhizoma Dioscoreae, purling withered Shu, Cortex araliae chinensis, Herba Calystegiae Japonicae, Radix seu Herba Spiranthis Lanceae, spirulina, Herba mesonae chinensis, Herba Hypoestis purpureae, Radix Malvae rotundifoliae, Rhizoma Polygonati Verticillati, Ramulus et folium taxi cuspidatae and Herba Melicae Scabrosae are cleaned, put into container, add the distilled water of 8～12 times of amounts, soak after 5～6 hours, boil 4～5 hours, extract; Again add 6～10 times of amount distilled water, boil 2～3 hours, extract; Finally, add 4～8 times of amount distilled water, heated and boiled 1～2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, for subsequent use;
(2) Rhizoma seu herba Asystasiellae Chinensis is cut into slices, dry in the sun, carries out pulverization process after drying, and grinds into powder, crosses 160 order fine powders, for subsequent use;
(3) Caulis et Folium Calystegiae sepii is cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(4) Semen Abutili is cleaned, section, dries, and slow fire is fried, and fries to 5～10 minutes, takes out, and grinds into powder, crosses 120 order fine powders, for subsequent use;
(5) Fructus Pandani tectorii is cleaned, immersed 65% alcohol solution dipping 3-4 hour of 6 times of amounts, heating and refluxing extraction 1-2 hour, filters, and obtains filtrate for subsequent use;
(6) filtrate made above-mentioned steps (1)-(5), fine powder and juice are mixed, add adjuvant, utilize modern advanced pharmacy science and technology, make oral liquid, both the Chinese medicine preparation for the treatment of diabetes of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
Rhizoma seu herba Asystasiellae Chinensis: bitter in the mouth is light, cool in nature.Return lung meridian.Removing stasis to stop bleeding, reunion of fractured tendons and bones, inducing diuresis to remove edema, heat-clearing and toxic substances removing.Main haematemesis, has blood in stool, traumatic hemorrhage, and traumatic injury congestive edema, sprain fracture, rheumatism limb is swollen, ascites, skin infection festers, and furuncle is swollen, laryngopharynx swelling and pain." Zhejiang conventional medical herbs among the people " carries: " heat-clearing and toxic substances removing, promoting blood circulation and hemostasis.
Control traumatic hemorrhage, sprain, furuncle and phyma, ulcer of the lower limb, ascites, pulmonary tuberculosis.”
Rhizoma Dioscoreae: sweet, flat.Return spleen, lung, kidney channel.Spleen reinforcing nourishing the stomach, the lung benefiting that promotes the production of body fluid, the kidney invigorating arresting seminal emission.For insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, and leukorrhagia, frequent micturition, deficiency-heat is quenched one's thirst.Rhizoma Dioscoreae (parched with bran) spleen reinforcing stomach invigorating.For insufficiency of the spleen lack of appetite, the loose stool of having loose bowels, leukorrhagia." herbal classic " carries: ", except cold and heat pathogen, invigorating the spleen and replenishing QI power, longue meat, takes normal hearing and eyesight for a long time for main damaging the spleen and stomach, tonify deficiency.”
Fructus Pandani tectorii: acrid in the mouth is light, cool in nature.Return kidney,spleen,liver, stomach warp.Spleen reinforcing benefit blood, promoting the circulation of QI to relieve pain, the dampness removing that reduces phlegm, improving eyesight.Main dysentery, stomachache, cough, hernia, orchitis, diabetes, hemorrhoid dysuria, the raw cataracta of order." Luchuan book on Chinese herbal medicine " carries: " control hernia, dysuria, diabetes.”
Purling withered tree: sweet, bitter, puckery, cool.Clearing away damp-heat, detumescence poison, hemostasis, pain relieving.Take orally and control diarrhoea, traumatic injury, parotitis, diabetes.Parotitis is controlled in external, furuncle carbuncle, mastitis from the beginning of, traumatic injury, traumatic hemorrhage.
Cortex araliae chinensis: sweet, micro-hardship, flat.Expelling wind and removing dampness, inducing diuresis to remove edema, promoting blood circulation and stopping pain.For hepatitis, lymphadenectasis, oedema due to nephritis, diabetes, leucorrhea, stomachache, rheumatic arthritis, lumbago and skelalgia, traumatic injury.
Herba Calystegiae Japonicae: sweet, cold.Return spleen, stomach, large intestine, small intestine meridian.Removing heat from the liver, YIN nourishing, diuresis.Main excessive rising of liver-YANG, dizziness, dizzy, dysuria.The doctor of Soviet Union " Chinese herbal medicine handbook " is carried: " rhizome invigorating the stomach and promoting digestion, strong, sharp defecation.Control dyspepsia, diabetes, and can promote trauma fracture healing.”
Radix seu Herba Spiranthis Lanceae: sweet, hardship, flat.GUIXIN, lung meridian.Supplementing QI and nourishing YIN, heat-clearing and toxic substances removing.Main weak after being ill, yin asthenia generating intrinsic heat, cough is spitted blood, dizziness, lumbago is aching and limp, diabetes, seminal emission, stranguria with turbid discharge leukorrhagia, laryngopharynx swelling and pain, venom, burn and scald, skin infection carbuncle." Nanning City's medicine will " carries: " heat clearing away, lung moistening.Control heat syndrome cough.”
Spirulina: alleviate the toxicity of cancer radiation, chemotherapy, improve immunologic function, reduce blood fat.The auxiliary treatment of main cancer; Hyperlipemia; Iron deficiency anemia; Diabetes; Malnutrition; Body void after being ill.
Herba mesonae chinensis: sweet in the mouth; Light; Cold in nature.Relieve summer heat; Heat clearing away; Removing heat from blood; Removing toxic substances.Person in master, diabetes, jaundice, has loose bowels, dysentery, hypertension, fat meat, arthralgia, acute nephritis, acute toothache, burn and scald, erysipelas, syphilis, paint is irritated." middle traditional Chinese medicines are planted illustrated handbook " carries: " be cool, thirst-quenching except summer-heat agent.Herb decoction, controls diabetes.”
Semen Abutili: sweet, cold, temperature.Clearing away heat-damp and promoting diuresis, invigorating the spleen and replenishing QI, for icterohepatitis, the deficiency of vital energy is weak, soreness of the waist and knees, the empty spontaneous perspiration of body, proctoptosis, uterine prolapse, chronic nephritis, diabetes.
Herba Hypoestis purpureae: sweet light, be slightly cold.Antiinflammatory, dissipating blood stasis, hemostasis, cough-relieving.Control pulmonary tuberculosis hemoptysis, bronchitis, diabetes.
Radix Malvae rotundifoliae: sweet in the mouth, warm in nature.Invigorating the spleen and replenishing QI, holder sore, controls the labor of suffering from a deficiency of the kidney, anemia, scorching edema, diabetes." Shaanxi Chinese herbal medicine " carries: " invigorating the spleen and replenishing QI, holder sore, diuresis, lactogenesis.Control asthenia, anemia, pulmonary tuberculosis, proctoptosis, uterine prolapse, oedema due to nephritis, diabetes, skin ulcer is swollen to be difficult for passing through inside, hypogalactia.”
Rhizoma Polygonati Verticillati: sweet, micro-hardship, cool.Nourishing the liver and kidney, YIN nourishing and the production of body fluid promoting.For neurasthenia, hypertension, headache, throat pain, quenches one's thirst, dry mouth and tougue." the sweet peaceful blue or green Chinese herbal medicine choosing in Shan " carries: " spleen reinforcing lung moistening, promotes the production of body fluid.Control pulmonary tuberculosis, weak, thirsty after being ill, neurasthenia, headache due to hyperactivity of liver-YANG, inappetence, lassitude loin and legs, diabetes.”
Caulis et Folium Calystegiae sepii: pungent, micro-sweet, micro-hardship, flat.Return spleen, kidney channel.Heat-clearing and toxic substances removing, main erysipelas." pharmacologys of traditional Chinese medicines " are carried: " be diuretic, control diabetes.”
Ramulus et folium taxi cuspidatae: light; Property is put down.Return kidney channel.Inducing diuresis to remove edema, main nephritis edema, dysuria, diabetes." book on Chinese herbal medicine pushes away old " carries: " diuresis is stimulated the menstrual flow.Control nephropathy, diabetes.”
Herba Melicae Scabrosae: sweet, light, cool, cold, nontoxic.Heat-clearing and toxic substances removing, cooling blood for hemostasis, dampness removing, expelling summer-heat, diuresis.Be used for catching a cold high hot, heatstroke, urinary tract infection, oedema due to nephritis, icterohepatitis, diabetes, children's's heat of a specified duration is not moved back.Main calentura excessive thirst, spits blood, epistaxis, hemoptysis, hematuria, metrorrhagia, jaundice, stranguria with turbid discharge leukorrhagia, dysentery." Deserts in China area medicinal plants " carries: " relieving stranguria by diuresis, heat clearing away.Control urinary tract infection, oedema due to nephritis, cat fever, icterohepatitis, diabetes.”
The present invention compared with prior art, has following beneficial effect:
1, invention Chinese medicine preparation has supplementing QI and nourishing YIN, replenishing body fluid and clearing away heat pathogen, reduce effect of blood glucose, the lazy gas of few speech, asthenia fatigue, puffiness due to deficiency that treatment diabetes are caused are unable or day by day become thin, body of the tongue is fat large or have the deficiency of vital QI phenomenons such as indentation to have significant therapeutic effect.
2, Chinese medicine preparation of the present invention is made up of pure Chinese medicine, toxic and side effects is little, treating both the principal and secondary aspects of a disease, can effectively control blood glucose, glucose in urine, the function such as energy, muscle power is restored, to pancreatic tissue, damage has certain repair, have evident in efficacy, non-relapse after healing, with low cost, the feature of safety and stability.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
Raw material composition and the weight of Chinese medicine preparation effective ingredient of the present invention are:
The purling withered tree 60g of Rhizoma seu herba Asystasiellae Chinensis 70g Rhizoma Dioscoreae 66g Fructus Pandani tectorii 65g
Cortex araliae chinensis 60g Herba Calystegiae Japonicae 55g Radix seu Herba Spiranthis Lanceae 53g spirulina 48g
Herba mesonae chinensis 45g Semen Abutili 43g Herba Hypoestis purpureae 40g Radix Malvae rotundifoliae 35g
Rhizoma Polygonati Verticillati 32g Caulis et Folium Calystegiae sepii 30g Ramulus et folium taxi cuspidatae 20g Herba Melicae Scabrosae 18g.
Treat a preparation method for the Chinese medicine preparation of diabetes, comprise following processing step:
(1) Rhizoma Dioscoreae, purling withered Shu, Cortex araliae chinensis, Herba Calystegiae Japonicae, Radix seu Herba Spiranthis Lanceae, spirulina, Herba mesonae chinensis, Herba Hypoestis purpureae, Radix Malvae rotundifoliae, Rhizoma Polygonati Verticillati, Ramulus et folium taxi cuspidatae and Herba Melicae Scabrosae are cleaned, put into container, add the distilled water of 8～12 times of amounts, soak after 5～6 hours, boil 4～5 hours, extract; Again add 6～10 times of amount distilled water, boil 2～3 hours, extract; Finally, add 4～8 times of amount distilled water, heated and boiled 1～2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, for subsequent use;
(2) Rhizoma seu herba Asystasiellae Chinensis is cut into slices, dry in the sun, carries out pulverization process after drying, and grinds into powder, crosses 160 order fine powders, for subsequent use;
(3) Caulis et Folium Calystegiae sepii is cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(4) Semen Abutili is cleaned, section, dries, and slow fire is fried, and fries to 5～10 minutes, takes out, and grinds into powder, crosses 120 order fine powders, for subsequent use;
(5) Fructus Pandani tectorii is cleaned, immersed 65% alcohol solution dipping 3-4 hour of 6 times of amounts, heating and refluxing extraction 1-2 hour, filters, and obtains filtrate for subsequent use;
(6) filtrate made above-mentioned steps (1)-(5), fine powder and juice are mixed, add adjuvant, utilize modern advanced pharmacy science and technology, make oral liquid, both the Chinese medicine preparation for the treatment of diabetes of the present invention.
Embodiment 2
Raw material composition and the weight of Chinese medicine preparation effective ingredient of the present invention are:
The purling withered tree 55g of Rhizoma seu herba Asystasiellae Chinensis 65g Rhizoma Dioscoreae 60g Fructus Pandani tectorii 60g
Cortex araliae chinensis 55g Herba Calystegiae Japonicae 51g Radix seu Herba Spiranthis Lanceae 50g spirulina 45g
Herba mesonae chinensis 41g Semen Abutili 40g Herba Hypoestis purpureae 35g Radix Malvae rotundifoliae 31g
Rhizoma Polygonati Verticillati 30g Caulis et Folium Calystegiae sepii 25g Ramulus et folium taxi cuspidatae 18g Herba Melicae Scabrosae 16g.
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 3
Raw material composition and the weight of Chinese medicine preparation effective ingredient of the present invention are:
The purling withered tree 50g of Rhizoma seu herba Asystasiellae Chinensis 60g Rhizoma Dioscoreae 55g Fructus Pandani tectorii 54g
Cortex araliae chinensis 48g Herba Calystegiae Japonicae 43g Radix seu Herba Spiranthis Lanceae 40g spirulina 37g
Herba mesonae chinensis 34g Semen Abutili 32g Herba Hypoestis purpureae 29g Radix Malvae rotundifoliae 27g
Rhizoma Polygonati Verticillati 25g Caulis et Folium Calystegiae sepii 21g Ramulus et folium taxi cuspidatae 16g Herba Melicae Scabrosae 15g.
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 4
Raw material composition and the weight of Chinese medicine preparation effective ingredient of the present invention are:
The purling withered tree 45g of Rhizoma seu herba Asystasiellae Chinensis 55g Rhizoma Dioscoreae 50g Fructus Pandani tectorii 48g
Cortex araliae chinensis 40g Herba Calystegiae Japonicae 35g Radix seu Herba Spiranthis Lanceae 32g spirulina 30g
Herba mesonae chinensis 26g Semen Abutili 25g Herba Hypoestis purpureae 23g Radix Malvae rotundifoliae 22g
Rhizoma Polygonati Verticillati 20g Caulis et Folium Calystegiae sepii 18g Ramulus et folium taxi cuspidatae 15g Herba Melicae Scabrosae 14g.
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 5
Raw material composition and the weight of Chinese medicine preparation effective ingredient of the present invention are:
The purling withered tree 40g of Rhizoma seu herba Asystasiellae Chinensis 45g Rhizoma Dioscoreae 40g Fructus Pandani tectorii 36g
Cortex araliae chinensis 35g Herba Calystegiae Japonicae 30g Radix seu Herba Spiranthis Lanceae 25g spirulina 24g
Herba mesonae chinensis 22g Semen Abutili 20g Herba Hypoestis purpureae 18g Radix Malvae rotundifoliae 18g
Rhizoma Polygonati Verticillati 16g Caulis et Folium Calystegiae sepii 15g Ramulus et folium taxi cuspidatae 13g Herba Melicae Scabrosae 12g.
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Clinical data:
1, case selection:
As the Chinese medicine preparation for the treatment of diabetes, the routine clinical observation of diabetics 200 that selection is made a definite diagnosis, patient is divided into two groups for the treatment of group and matched groups, treatment group 100 examples, wherein male's 54 examples at random, women's 46 examples, 41～70 years old age, 45.4 years old mean age, the shortest person of the course of disease 8 months, elder 15 years, average 7.9 years.Matched group 100 examples, wherein male's 53 examples, women's 47 examples, 42～72 years old age, 44.7 years old mean age, the shortest person of the course of disease 7 months, elder 14 years, average 7.2 years.The course of disease, the degrees of symptoms for the treatment of group and two groups of cases of matched group are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group is taken Chinese medicine preparation of the present invention, oral, every day 3 times, each 20ml; Within 7 days, be 1 course for the treatment of, 2 courses for the treatment of of the lighter, can fully recover severe one 3-4 the course for the treatment of.
Matched group is taken TANGMAIKANG KELI, oral.One time 1 bag, 3 times on the one; Within 10 days, be 1 course for the treatment of, 3 courses for the treatment of of the lighter, 6 courses for the treatment of of severe one, the person of being in a bad way is conventionally invalid.
3, efficacy determination:
(1) cure: diabetic symptom all disappears, and physical recovery is normal, body index recovers normal on inspection.
(2) effective: diabetic symptom disappears, and body index recovers normal substantially on inspection.
(3) effective: diabetic symptom disappears substantially, body index part takes a turn for the better on inspection.
(4) invalid: by treating rear symptom without being clearly better.
4, result:
Take in the treatment group of Chinese medicine preparation of the present invention, cure 37 examples, effective 34 examples, effective 27 examples, invalid 2 examples, cure rate 37%, total effective rate 98%.
In matched group, cure 15 examples, effective 18 examples, effective 20 examples, invalid 47 examples, cure rate 15%, total effective rate 53%.
Above result demonstration, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is given an example:
1, Dong, female, 47 years old, people from Wuhan City, Hubei Province, certain worker of factory.Suffer from diabetes 27 years, insulin injection 16 years, the long-term pruritus of skin, all there is ulcer in oral cavity every month, needs three days ability of transfusion to take a turn for the better, and sleeps bad, defecate very dry, puffiness of face, malaise; On June 10th, 2010 starts the diagnosis and treatment of Lai Wo institute, takes Chinese medicine preparation of the present invention, oral, every day 3 times, each 20ml, 1 the course for the treatment of skin pruritus alleviate, oral ulcer is clearly better, take after 2 courses for the treatment of, according to informing that face eliminates edema gradually, whole body is no longer weak, after 3 courses for the treatment of, blood sugar level is normal, just stop injection of insulin, or else use infusion treatment, health is obviously improved.Skin recovers normally, there is no aphtha completely now, and stool is normal, can also go out amusement every afternoon.
2, Wei, man, 52 years old, the Yangzhou people of Jiangsu Province, civil servant, headache, dreaminess, weak all at ordinary times, has hyperglycemia medical history more than 2 years, takes hypoglycemic medicine always; Take Chinese medicine preparation of the present invention in October, 2011, adheres to every day three times, taking after 1 course for the treatment of, and the mental status is clearly better, blood glucose declines to some extent, and the state of an illness starts to take a turn for the better, and then takes after 4 courses for the treatment of, and blood glucose value drops to normal level, so far health is fine, and glucostasis, without recurrence.
3, Pueraria lobota, man, 65 years old, people from Hefei City, Anhui Province, unemployed, suffer from diabetes 7 years.Take 1 course for the treatment of of Chinese medicine preparation of the present invention, every day 3 times, each 20ml, the intestines and stomach takes a turn for the better, and becomes clear depending on thing, and health is salubrious, fully recovers after taking 3 courses for the treatment of, follows up a case by regular visits to, so far not recurrence.
4, cover certain, female, 72 years old, people from Guangzhou, Guangdong, retired professor, suffer from diabetes 8 years, because not finding suitable medicine, every day to be all subject to the torment of hyperglycemia in the past, there is pathological changes in optical fundus, substantially blind, with hypertension, coronary heart disease, mood is very bad, likes very much angry anger, and blood glucose is high; Take Chinese medicine preparation of the present invention in November, 2010, takes after 1 course for the treatment of, and hypertension, coronary heart disease are recovered normally substantially, and eyes have some to take a turn for the better, and then take 3 courses for the treatment of, and vision restoration is normal, blood glucose held stationary.
Claims (5)
1. a Chinese medicine preparation for the treatment of diabetes, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
30～65 parts, 34～70 parts of purling withered trees of 35～70 parts of Fructus Pandani tectoriis of 40～75 portions of Rhizoma Dioscoreaes of Rhizoma seu herba Asystasiellae Chinensis
20～51 parts of 22～55 parts of spirulinas of 25～60 parts of Radix seu Herba Spiranthis Lanceae of 26～63 parts of Herba Calystegiae Japonicae of Cortex araliae chinensis
15～40 parts of 15～45 parts of Radix Malvae rotundifoliaes of 18～46 portions of Herba Hypoestis purpureaes of 20～50 parts of Semen Abutili of Herba mesonae chinensis
10～20 parts of 10～30 parts of Herba Melicae Scabrosaes of 13～33 parts of Ramulus et folium taxi cuspidataes of 13～35 parts of Caulis et Folium Calystegiae sepii of Rhizoma Polygonati Verticillati.
2. a kind of Chinese medicine preparation for the treatment of diabetes according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
40～60 parts, 36～65 parts of purling withered trees of 40～66 parts of Fructus Pandani tectoriis of 45～70 portions of Rhizoma Dioscoreaes of Rhizoma seu herba Asystasiellae Chinensis
24～48 parts of 25～53 parts of spirulinas of 30～55 parts of Radix seu Herba Spiranthis Lanceae of 35～60 parts of Herba Calystegiae Japonicae of Cortex araliae chinensis
18～35 parts of 18～40 parts of Radix Malvae rotundifoliaes of 20～43 portions of Herba Hypoestis purpureaes of 22～45 parts of Semen Abutili of Herba mesonae chinensis
12～18 parts of 13～20 parts of Herba Melicae Scabrosaes of 15～30 parts of Ramulus et folium taxi cuspidataes of 16～32 parts of Caulis et Folium Calystegiae sepii of Rhizoma Polygonati Verticillati.
3. a kind of Chinese medicine preparation for the treatment of diabetes according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
45～55 parts, 48～60 parts of purling withered trees of 50～60 parts of Fructus Pandani tectoriis of 55～65 portions of Rhizoma Dioscoreaes of Rhizoma seu herba Asystasiellae Chinensis
30～45 parts of 32～50 parts of spirulinas of 35～51 parts of Radix seu Herba Spiranthis Lanceae of 40～55 parts of Herba Calystegiae Japonicae of Cortex araliae chinensis
22～31 parts of 23～35 parts of Radix Malvae rotundifoliaes of 25～40 portions of Herba Hypoestis purpureaes of 26～41 parts of Semen Abutili of Herba mesonae chinensis
14～16 parts of 15～18 parts of Herba Melicae Scabrosaes of 18～25 parts of Ramulus et folium taxi cuspidataes of 20～30 parts of Caulis et Folium Calystegiae sepii of Rhizoma Polygonati Verticillati.
4. a kind of Chinese medicine preparation for the treatment of diabetes according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
50 parts, 54 parts of purling withered trees of 55 parts of Fructus Pandani tectoriis of 60 portions of Rhizoma Dioscoreaes of Rhizoma seu herba Asystasiellae Chinensis
37 parts of 40 parts of spirulinas of 43 parts of Radix seu Herba Spiranthis Lanceae of 48 parts of Herba Calystegiae Japonicae of Cortex araliae chinensis
27 parts of 29 parts of Radix Malvae rotundifoliaes of 32 portions of Herba Hypoestis purpureaes of 34 parts of Semen Abutili of Herba mesonae chinensis
15 parts of 16 parts of Herba Melicae Scabrosaes of 21 parts of Ramulus et folium taxi cuspidataes of 25 parts of Caulis et Folium Calystegiae sepii of Rhizoma Polygonati Verticillati.
5. a preparation method for the treatment of the Chinese medicine preparation of diabetes as described in claim 1-4 any one, is characterized in that: comprise following processing step:
(1) Rhizoma Dioscoreae, purling withered Shu, Cortex araliae chinensis, Herba Calystegiae Japonicae, Radix seu Herba Spiranthis Lanceae, spirulina, Herba mesonae chinensis, Herba Hypoestis purpureae, Radix Malvae rotundifoliae, Rhizoma Polygonati Verticillati, Ramulus et folium taxi cuspidatae and Herba Melicae Scabrosae are cleaned, put into container, add the distilled water of 8～12 times of amounts, soak after 5～6 hours, boil 4～5 hours, extract; Again add 6～10 times of amount distilled water, boil 2～3 hours, extract; Finally, add 4～8 times of amount distilled water, heated and boiled 1～2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, for subsequent use;
(2) Rhizoma seu herba Asystasiellae Chinensis is cut into slices, dry in the sun, carries out pulverization process after drying, and grinds into powder, crosses 160 order fine powders, for subsequent use;
(3) Caulis et Folium Calystegiae sepii is cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(4) Semen Abutili is cleaned, section, dries, and slow fire is fried, and fries to 5～10 minutes, takes out, and grinds into powder, crosses 120 order fine powders, for subsequent use;
(5) Fructus Pandani tectorii is cleaned, immersed 65% alcohol solution dipping 3-4 hour of 6 times of amounts, heating and refluxing extraction 1-2 hour, filters, and obtains filtrate for subsequent use;
(6) filtrate made above-mentioned steps (1)-(5), fine powder and juice are mixed, add adjuvant, make oral liquid, both the Chinese medicine preparation for the treatment of diabetes of the present invention.
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| CN103933394A (en) * | 2014-04-14 | 2014-07-23 | 司晓东 | Chinese herbal medicine for treating diabetes and preparation method thereof |
| CN103948844A (en) * | 2014-04-28 | 2014-07-30 | 青岛市城阳区人民医院 | Traditional Chinese herbal medicinal formula for treating diabetes mellitus and preparation method thereof |
| CN104606538A (en) * | 2015-01-10 | 2015-05-13 | 陈霞 | Traditional Chinese medicine health product for preventing and treating diabetes |
| CN104758613A (en) * | 2015-04-07 | 2015-07-08 | 肖�琳 | Biological capsule for treating diabetes and preparation method of biological capsule |
| CN106361983A (en) * | 2016-08-28 | 2017-02-01 | 徐林 | Capsule for realizing adjuvant treatment on diabetes and preparation method of capsule |
| CN106421399A (en) * | 2016-11-27 | 2017-02-22 | 莫泽庸 | Medicament for treating diabetes and preparation method of medicament |
| CN107889908A (en) * | 2017-11-24 | 2018-04-10 | 贵州省凤冈县黔雨枝生态茶业有限公司 | A kind of Hypoylycemic health tea and preparation method thereof |
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| CN100404066C (en) * | 2006-06-08 | 2008-07-23 | 管晓峰 | Chinese medicine for treating diabetes mellitus and its preparation |
| CN102579915B (en) * | 2012-03-06 | 2013-07-10 | 杜中勤 | Medicine for treating wound non-healing of diabetics |
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