CN103393857A - Drug for curing hepatitis and preparation method thereof - Google Patents
Drug for curing hepatitis and preparation method thereof Download PDFInfo
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- CN103393857A CN103393857A CN2013103615179A CN201310361517A CN103393857A CN 103393857 A CN103393857 A CN 103393857A CN 2013103615179 A CN2013103615179 A CN 2013103615179A CN 201310361517 A CN201310361517 A CN 201310361517A CN 103393857 A CN103393857 A CN 103393857A
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Abstract
The invention discloses a drug for curing hepatitis and a preparation method thereof, and belongs to the field of traditional Chinese medicine. The drug comprises following effective raw materials: whitebackleaf mallotus root, iris japonica thumb, alum, lygodium japonicum, salix matsudana koidz, herb of shady groundsel, triquetrous tadehagi herb, flying squirrel feces, artemisia japonica, fortune holly fern rhizome, phellodendron, hypecoum erectum, cornus officinalis, sago seed, turtle shell and fiveleaf akebia fruit. The drug has the functions of nourishing liver, clearing heat, removing toxicity and tranquilizing by nourishing the heart, and has prominent curative effects on inhibiting and clearing hepatitis virus, adjusting human immunity functions, recovering liver form and functions, and preventing and curing hepatic fibrosis and liver cancer. The drug has the advantages of low cost, user-friendliness, easy absorption, and quick and good curative effect, achieves the goal of curing both the symptom and the root causes, and has no side or toxic effects and a very good curative effect on hepatitis.
Description
Affiliated technical field
The present invention relates to the field of Chinese medicines, relate in particular to a kind of medicine and preparation method for the treatment of hepatitis.
Background technology
Hepatitis is the inflammation of liver, and the healthy of people in serious harm, and due to the cause of disease complexity of a great variety, pathogenic of hepatitis, as in time treatment or therapeutic effect are not good, the state of an illness will worsen.Hepatitis typically refers to by multiple paathogenic factor--as virus, parasite, chemical toxicant, medicine and poisonous substance, ethanol etc., and the infringement liver, make the cell of liver be damaged, the function of liver suffers damage, and it can cause a series of malaise symptoms of health, and liver function index is abnormal.Viral hepatitis (viralhepatitis) be caused by multiple different hepatitis viruss one group take the liver evil as main infectious disease, according to etiological diagnosis, hepatitis virus has 5 kinds at least, be first, second, third, fourth, hepatitis E virus, cause respectively first, second, third, fourth, hepatitis E, i.e. hepatitis A (hepatitis A), hepatitis B (hepatitis B), hepatitis C (hepatitisC), hepatitis D (hepatitis D) and hepatitis E (hepatitis E).Another is called hepatitis G, and is more rare.Viral hepatitis is mainly by excrement-mouth, blood or body fluid communication, jaundice occurs take tired, loss of appetite, hepatomegaly, abnormal liver function as main manifestations, some cases clinically, and symptomless infection is common.
At present, medically to the treatment of hepatitis, what mainly adopt is antiviral therapy, because antiviral therapy has its clear and definite indication and contraindication, and the impact that is subjected to the reasons such as economic condition, the various effect of drugs for the treatment of hepatitis are not very desirable, treatment time is long, cure rate is low, and side effect is large.
Summary of the invention
The invention provides a kind of medicine and preparation method for the treatment of hepatitis, medicine of the present invention has the effect of keeping fit liver, heat-clearing and toxic substances removing, liver heat removing and eyesight improving, tranquilizing by nourishing the heart, to suppressing and removing hepatitis virus, adjustment immune function of human body, recovery liver morphology and function, control hepatic fibrosis and canceration, has significant curative effect; Drug therapy cost of the present invention is low, taking convenience, be easy to absorb, instant effect, good effect, reach the purpose for the treatment of both the principal and secondary aspects of a disease, has no side effect, and treatment hepatitis is had good effect.
For achieving the above object, technical scheme of the present invention is implemented as follows:
A kind of medicine for the treatment of hepatitis, raw material composition and the parts by weight of making described effective ingredient are:
42～67 parts of 46～72 parts of Spora Lygodii of 47～72 parts of Alumens of 52～77 parts of Rhizoma Iridis Japonicaes of Folium Malloti Apeltae
32～53 parts of 34～57 parts of Oletum Trogopteroris of 37～62 portions of Herba Desmodii Triquetri (Herba Tadehagi Triquetri)s of 38～65 parts of Herba senecionis nemorensis of Folium et Cacumen Salicis Matsudanae
27～40 parts of 27～47 parts of Radix Hypecol Erecti of 26～45 portions of Cortex Phellodendris of 29～49 parts of Cyrtomium fortunei J. Sm.s of Herba Artemisiae Japonicae
7～27 parts of 17～32 parts of Fructus Akebiaes of 19～36 parts of Carapax Trionycis of 22～37 parts of Cycas revoluta Thunb.s of Fructus Corni.
Raw material composition and the parts by weight of making described effective ingredient are:
47～64 parts of 48～67 parts of Spora Lygodii of 52～69 parts of Alumens of 57～72 parts of Rhizoma Iridis Japonicaes of Folium Malloti Apeltae
36～50 parts of 37～54 parts of Oletum Trogopteroris of 41～57 portions of Herba Desmodii Triquetri (Herba Tadehagi Triquetri)s of 42～62 parts of Herba senecionis nemorensis of Folium et Cacumen Salicis Matsudanae
28～37 parts of 30～42 parts of Radix Hypecol Erecti of 32～44 portions of Cortex Phellodendris of 35～47 parts of Cyrtomium fortunei J. Sm.s of Herba Artemisiae Japonicae
10～24 parts of 20～27 parts of Fructus Akebiaes of 22～32 parts of Carapax Trionycis of 25～34 parts of Cycas revoluta Thunb.s of Fructus Corni.
Raw material composition and the parts by weight of making described effective ingredient are:
50～60 parts of 52～62 parts of Spora Lygodii of 57～63 parts of Alumens of 62～67 parts of Rhizoma Iridis Japonicaes of Folium Malloti Apeltae
40～47 parts of 42～52 parts of Oletum Trogopteroris of 44～52 portions of Herba Desmodii Triquetri (Herba Tadehagi Triquetri)s of 47～57 parts of Herba senecionis nemorensis of Folium et Cacumen Salicis Matsudanae
31～34 parts of 32～37 parts of Radix Hypecol Erecti of 35～42 portions of Cortex Phellodendris of 37～43 parts of Cyrtomium fortunei J. Sm.s of Herba Artemisiae Japonicae
12～19 parts of 22～24 parts of Fructus Akebiaes of 26～29 parts of Carapax Trionycis of 27～32 parts of Cycas revoluta Thunb.s of Fructus Corni.
Raw material composition and the parts by weight of making described effective ingredient are:
55 parts of 57 parts of Spora Lygodii of 60 parts of Alumens of 65 parts of Rhizoma Iridis Japonicaes of Folium Malloti Apeltae
43 parts of 47 parts of Oletum Trogopteroris of 48 portions of Herba Desmodii Triquetri (Herba Tadehagi Triquetri)s of 52 parts of Herba senecionis nemorensis of Folium et Cacumen Salicis Matsudanae
32 parts of 35 parts of Radix Hypecol Erecti of 38 portions of Cortex Phellodendris of 40 parts of Cyrtomium fortunei J. Sm.s of Herba Artemisiae Japonicae
15 parts of 23 parts of Fructus Akebiaes of 27 parts of Carapax Trionycis of 30 parts of Cycas revoluta Thunb.s of Fructus Corni.
A kind of preparation method for the treatment of the medicine of hepatitis comprises following processing step:
(1) Alumen, Radix Hypecol Erecti, Fructus Corni and Cycas revoluta Thunb. are mixed, carry out pulverization process after mix homogeneously, grind into powder, cross 120 order fine powders, standby;
(2) Rhizoma Iridis Japonicae, Spora Lygodii, Folium et Cacumen Salicis Matsudanae, Herba senecionis nemorensis, Herba Artemisiae Japonicae, Cyrtomium fortunei J. Sm., Cortex Phellodendri and Fructus Akebiae are cleaned, put into container, add the distilled water of 8～12 times of amounts, soak after 4～5 hours, boiled 3～4 hours, extract; Again add 6～8 times of amount distilled water, boiled 2～3 hours, extract; Finally, add 4～6 times of amount distilled water, heated and boiled 1～2 hour, extract; Merge three times extracting solution, filter, obtain filtrate, be condensed into 50 ℃ of lower relative densities and be 1.10～1.14 thick paste, standby;
(3) Folium Malloti Apeltae is cleaned, chopping, put into container, strand juice, and filter impurity, stay juice standby;
(4) Oletum Trogopterori is put a pot interior little stir-fry, sprayed rice vinegar, then fry to little and do, take out when surface is slightly glossy, dry, grind into powder, cross 200 order fine powders, standby;
(5) Herba Desmodii Triquetri (Herba Tadehagi Triquetri) is cleaned, immersed 85% the alcohol solution dipping 1～2 hour of 5 times of amounts, heating extraction 3 hours, reclaim ethanol, filters, and under 60 ℃ of environment of filtrate simmer down to, the thick paste of relative density 1.20～1.25, standby;
(6) sandy soil are put heating in pot, loose to sandy soil, get Carapax Trionycis and put into pot and fry to the little yellow of epidermis, take out sieve and remove sandy soil, put into the vinegar basin and slightly soak, every 100 jin with 30 jin of vinegar, taking-up is dried, and grinds into powder, crosses 160 order fine powders, and is standby;
(7) fine powder that above-mentioned steps (1)～(6) are made, thick paste and juice mix, and add adjuvant, utilize modern advanced pharmacy science and technology, make capsule, both the medicine for the treatment of hepatitis of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
Folium Malloti Apeltae: little hardship, puckery, flat; Easing the affected liver is invigorated blood circulation, invigorating the spleen for eliminating dampness, and convergence is taken off admittedly, anti-inflammation hemostasia.Be used for chronic hepatitis, hepatosplenomegaly, uterine prolapse, proctoptosis, leucorrhea, edema during pregnancy; Otitis media is controlled in external, furuncle and phyma, traumatic injury, traumatic hemorrhage." Nanning City's medicine will " carries: " heat clearing away, diuretic, wind-damp dispelling, pain relieving; Control stranguria with turbid discharge, hemorrhoid, traumatic injury, snakebite.Antipruritic, detumescence.”
Rhizoma Iridis Japonicae: hardship, cold, slightly poisonous; Heat-clearing and toxic substances removing, reducing swelling and alleviating pain.Be used for hepatitis, hepatomegaly, pain in the hepatic region, stomachache, the food stagnation distension, laryngopharynx swelling and pain, traumatic injury, relieving constipation by purgation, be used for constipation." Guizhou medical herbs " carries: " heat-clearing and toxic substances removing, admittedly take off parasite killing.”
Alumen: sour and astringent, cold, poisonous; Return lung, spleen, liver, large intestine, urinary bladder channel.Expectorant, dampness, antidiarrheal, hemostasis, detoxifcation, parasite killing.Control epilepsy, sore throat, remorse saliva is stopped up very, hepatitis, jaundice, general edema with yellowish skin, Stomach duodenum ulcer, uterine prolapse, leucorrhea, dysentery, epistaxis, aphtha of the mouth and tongue, skin ulcer hemorrhoid scabies, water, fire, insect bite." Japan hanako materia medica " carries: " except wind goes labor, expectorant is quenched the thirst, and warm water is hidden.Control apoplectic aphasia, scabies.Bathe with peach people, Herba Alii fistulosi soup, can perspire.”
Spora Lygodii: cold in nature, sweet in the mouth; Return bladder, small intestine meridian.Eliminating damp-heat, treating stranguria pain relieving.Be used for pyretic stranguria, sand Stranguria, stranguria with blood, stranguria marked by chyluria, Urethra astringent pain." Jiangxi medical herbs " carries: " heat-clearing and toxic substances removing, promoting urination to remove dampness.Treating the liver is scorching, renal edema, skin eczema, chickenpox, hematuria.Mumps, acute toothache, throat moth, diphtheria, herpes zoster, infantile malnutrition.”
Folium et Cacumen Salicis Matsudanae: mildly bitter flavor, cold in nature.Loose wind, damp eliminating, clearing away damp-heat.Control icterohepatitis, rheumatic arthritis, eczema.
Herba senecionis nemorensis: toil, cold; Enter liver, spleen channel.Heat-clearing and toxic substances removing.Control dysentery, enteritis, hepatitis, conjunctivitis, otitis media, carbuncle is treated poison, swelling around the eyes, carbuncle furuncle furunculosis.
Herba Desmodii Triquetri (Herba Tadehagi Triquetri): little hardship, puckery, cool.Heat-clearing and toxic substances removing, the removing food stagnancy dampness removing, parasite killing is anticorrosion.Be used for the prevention heatstroke, cold, fever, laryngopharynx swelling and pain, nephritis, icterohepatitis, enteritis, bacillary dysentery, infantile malnutrition, vomiting during pregnancy, Fructus Ananadis comosi is poisoning, children's's scleroderma.
Oletum Trogopterori: sweet, temperature; Enter liver, spleen channel.Promoting blood circulation to remove blood stasis, the parch to black hemostasis.Be used for trusted subordinate's congestion and have a pain, dysmenorrhea, the blood stasis amenorrhea, puerperal abdominalgia with blood stasis; Parch to black is controlled metrostaxis; Traumatic injury is controlled in external, Serpentis, insect bite wound.Amplification on Canon of Materia Medica carries: " the Oletum Trogopterori blood of passing through is meritorious, can not hemopoietic.Taste nebula in the sick eye of people arranged, come and go indefinite, be so blood institute disease also.The lid the heart being responsible for production of blood, blood stored in the liver, liver can be looked by blood, and it is contrary to reason that the order disease is not controlled blood.”
Herba Artemisiae Japonicae: bitter in the mouth, little sweet, cool in nature.Heat clearing away, removing heat from blood, detoxifcation.Catch a cold main summer, the pulmonary tuberculosis hectic fever, and spitting of blood, children's's infantile malnutrition with fever, epistaxis, have blood in stool, metrorrhagia, leukorrhagia, icterohepatitis, erysipelas, venom." Traditional Chinese Medicine in Sichuan will " carries: " energy clearing away heat from blood, liver-heat, ebb heat.Control cough, sphincter disturbance.”
Cyrtomium fortunei J. Sm.: hardship is slightly cold; Heat-clearing and toxic substances removing, cooling blood for calming endogenous wind, loose expectorant hemostasis, drive hook, ascarid, silk ribbon, pinworm parasites.Cure cold, the calentura macule, acute diseases such as cholera and sunstroke is dirty poisoning, malaria, dysentery, hepatitis, dizziness due to hyperactivity of liver-YANG headache, hematemesis hematochezia, metrorrhagia, leukorrhagia, acute mastitis, scrofula, traumatic injury." herbtherapy handbook commonly used is carried: " removing heat from blood, nourish blood for endogenous wind stopping, the clear sharp head, detoxifcation, dissipating blood stasis.Row pestilence while controlling, malaria, scrofula, sore swollen toxin, abdominal pain due to worm stagnation.”
Cortex Phellodendri: hardship, cold; Return kidney, bladder, large intestine channel.Heat clearing and damp drying, eliminating fire and detoxication, except the hectic fever due to YIN-deficiency clearind deficient heat.Be used for damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, flaccidity is warded off, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus, stir-baked CORTEX PHELLODENDRI with salt solution nourishing YIN to lower pathogenic fire.Be used for hyperactivity of fire caused by deficiency of YIN, the night sweat hectic fever due to YIN-deficiency." Japan hanako materia medica " carries: " feel at ease to control hectic fever due to YIN-deficiency except labor, wash liver, improving eyesight, many tears, xerostomia, heat in the heart, kill the infantile malnutrition worm, controls ascarid pained, scabies, processed with honey is controlled serious epistaxis, and hemorrhoidal hamorrhage rushes down blood, divides afterwards anxious heat to swell and ache.”
Radix Hypecol Erecti: hardship, cold, slightly poisonous.Heat-clearing and toxic substances removing, the antitussive pain relieving.Main cold, fever, cough, laryngopharynx swelling and pain, liver-heat conjunctival congestion, hepatitis, cholecystitis, dysentery, arthralgia." Henan Chinese herbal medicine handbook is carried: " heat clearing away, antiinflammatory, pain relieving.”
Fructus Corni: sour, puckery, tepor; Return liver, kidney channel.Liver and kidney tonifying, restrain astringent or styptic treatment for spontaneous sweatingly, and controlling nocturnal emission with astringent drugs reducing urination leukorrhagia stopping only collapses, and hidroschesis also has the effect of promoting the production of body fluid to quench thirst in addition.Be used for soreness of waist and knee joint, dizziness and tinnitus, forgetful emission and spermatorrhea, enuresis frequent micturition, bleeding not during menses, menoxenia, the profuse sweating collapse, interior-heat is quenched one's thirst." Mingyi Bielu " carries: " meaning can be beneficial smart, settling five organs.In addition, Fructus Corni is also controlled diabetes, and many and the Radix Rehmanniae, Radix Trichosanthis are equal to use.”
Cycas revoluta Thunb.: hardship, puckery, property is flat, and is poisonous; Return lung, liver, large intestine channel.The suppressing the hyperactive liver blood pressure lowering, relieving cough and expelling phlegm, restrain astringent or styptic treatment for spontaneous sweating.Main hypertension, chronic hepatitis, cough with copious phlegm, dysentery, seminal emission, leucorrhea, traumatic injury, knife injury.
Carapax Trionycis: salty, be slightly cold; Return liver, kidney channel.Nourishing YIN for suppressing the hyperactive YANG, hard masses softening and resolving, bring down a fever except steaming.Be used for fever due to yin deficiency, consumptive fever hectic fever due to YIN-deficiency, stirring-up of pathogenic wind in the interior resulting from deficiency, amenorrhea ， WEIJIA, chronic malaria malaria with splenomegaly.
Fructus Akebiae: sweet, cold.Liver-smoothing, qi-regulating, promoting blood circulation and stopping pain, relieving restlessness diuresis.The treating the liver peratodynia, the gastric heat food is slow-witted, excessive thirst, dysentery, lumbago, hypochondriac pain, hernia, dysmenorrhea, uterus tenesmus." Shaanxi Chinese herbal medicine " carries: " Shugan Yishen, invigorating the spleen and regulating the stomach; Control dyspepsia, stomachache, dysentery, hernia, uterus tenesmus.”
The present invention compared with prior art, has following beneficial effect:
1, medicine of the present invention has the effect of keeping fit liver, heat-clearing and toxic substances removing, liver heat removing and eyesight improving, tranquilizing by nourishing the heart, to suppressing and removing hepatitis virus, adjustment immune function of human body, recovery liver morphology and function, control hepatic fibrosis and canceration, has significant curative effect.
2, low, the taking convenience of Drug therapy cost of the present invention, be easy to absorb, instant effect, good effect, reach the purpose for the treatment of both the principal and secondary aspects of a disease, have no side effect, treatment hepatitis is had good effect.
The specific embodiment
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material of effective ingredient of the present invention forms and weight is:
Folium Malloti Apeltae 72g Rhizoma Iridis Japonicae 69g Alumen 67g Spora Lygodii 64g
Folium et Cacumen Salicis Matsudanae 62g Herba senecionis nemorensis 57g Herba Desmodii Triquetri (Herba Tadehagi Triquetri) 54g Oletum Trogopterori 50g
Herba Artemisiae Japonicae 47g Cyrtomium fortunei J. Sm. 44g Cortex Phellodendri 42g Radix Hypecol Erecti 37g
Fructus Corni 34g Cycas revoluta Thunb. 32g Carapax Trionycis 27g Fructus Akebiae 24g.
A kind of preparation method for the treatment of the medicine of hepatitis comprises following processing step:
(1) Alumen, Radix Hypecol Erecti, Fructus Corni and Cycas revoluta Thunb. are mixed, carry out pulverization process after mix homogeneously, grind into powder, cross 120 order fine powders, standby;
(2) Rhizoma Iridis Japonicae, Spora Lygodii, Folium et Cacumen Salicis Matsudanae, Herba senecionis nemorensis, Herba Artemisiae Japonicae, Cyrtomium fortunei J. Sm., Cortex Phellodendri and Fructus Akebiae are cleaned, put into container, add the distilled water of 8～12 times of amounts, soak after 4～5 hours, boiled 3～4 hours, extract; Again add 6～8 times of amount distilled water, boiled 2～3 hours, extract; Finally, add 4～6 times of amount distilled water, heated and boiled 1～2 hour, extract; Merge three times extracting solution, filter, obtain filtrate, be condensed into 50 ℃ of lower relative densities and be 1.10～1.14 thick paste, standby;
(3) Folium Malloti Apeltae is cleaned, chopping, put into container, strand juice, and filter impurity, stay juice standby;
(4) Oletum Trogopterori is put a pot interior little stir-fry, sprayed rice vinegar, then fry to little and do, take out when surface is slightly glossy, dry, grind into powder, cross 200 order fine powders, standby;
(5) Herba Desmodii Triquetri (Herba Tadehagi Triquetri) is cleaned, immersed 85% the alcohol solution dipping 1～2 hour of 5 times of amounts, heating extraction 3 hours, reclaim ethanol, filters, and under 60 ℃ of environment of filtrate simmer down to, the thick paste of relative density 1.20～1.25, standby;
(6) sandy soil are put heating in pot, loose to sandy soil, get Carapax Trionycis and put into pot and fry to the little yellow of epidermis, take out sieve and remove sandy soil, put into the vinegar basin and slightly soak, every 100 jin with 30 jin of vinegar, taking-up is dried, and grinds into powder, crosses 160 order fine powders, and is standby;
(7) fine powder that above-mentioned steps (1)～(6) are made, thick paste and juice mix, and add adjuvant, utilize modern advanced pharmacy science and technology, make capsule, both the medicine for the treatment of hepatitis of the present invention.
Usage and dosage: oral 3 times of every day, each 2, warm water delivery service after meal; 10 days is 1 course for the treatment of, and take effect common 2 courses for the treatment of, 3～4 recoveries from illness course for the treatment of.
Embodiment 2
The raw material of effective ingredient of the present invention forms and weight is:
Folium Malloti Apeltae 67g Rhizoma Iridis Japonicae 63g Alumen 62g Spora Lygodii 60g
Folium et Cacumen Salicis Matsudanae 57g Herba senecionis nemorensis 52g Herba Desmodii Triquetri (Herba Tadehagi Triquetri) 52g Oletum Trogopterori 47g
Herba Artemisiae Japonicae 43g Cyrtomium fortunei J. Sm. 42g Cortex Phellodendri 37g Radix Hypecol Erecti 34g
Fructus Corni 32g Cycas revoluta Thunb. 29g Carapax Trionycis 24g Fructus Akebiae 19g.
Process for preparing medicine processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 3
The raw material of effective ingredient of the present invention forms and weight is:
Folium Malloti Apeltae 65g Rhizoma Iridis Japonicae 60g Alumen 57g Spora Lygodii 55g
Folium et Cacumen Salicis Matsudanae 52g Herba senecionis nemorensis 48g Herba Desmodii Triquetri (Herba Tadehagi Triquetri) 47g Oletum Trogopterori 43g
Herba Artemisiae Japonicae 40g Cyrtomium fortunei J. Sm. 38g Cortex Phellodendri 35g Radix Hypecol Erecti 32g
Fructus Corni 30g Cycas revoluta Thunb. 27g Carapax Trionycis 23g Fructus Akebiae 15g.
Process for preparing medicine processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 4
The raw material of effective ingredient of the present invention forms and weight is:
Folium Malloti Apeltae 62g Rhizoma Iridis Japonicae 57g Alumen 52g Spora Lygodii 50g
Folium et Cacumen Salicis Matsudanae 47g Herba senecionis nemorensis 44g Herba Desmodii Triquetri (Herba Tadehagi Triquetri) 42g Oletum Trogopterori 40g
Herba Artemisiae Japonicae 37g Cyrtomium fortunei J. Sm. 35g Cortex Phellodendri 32g Radix Hypecol Erecti 31g
Fructus Corni 27g Cycas revoluta Thunb. 26g Carapax Trionycis 22g Fructus Akebiae 12g.
Process for preparing medicine processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 5
The raw material of effective ingredient of the present invention forms and weight is:
Folium Malloti Apeltae 57g Rhizoma Iridis Japonicae 52g Alumen 48g Spora Lygodii 47g
Folium et Cacumen Salicis Matsudanae 42g Herba senecionis nemorensis 41g Herba Desmodii Triquetri (Herba Tadehagi Triquetri) 37g Oletum Trogopterori 36g
Herba Artemisiae Japonicae 35g Cyrtomium fortunei J. Sm. 32g Cortex Phellodendri 30g Radix Hypecol Erecti 28g
Fructus Corni 25g Cycas revoluta Thunb. 22g Carapax Trionycis 20g Fructus Akebiae 10g.
Process for preparing medicine processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Clinical data:
1, case is selected:
, as the medicine for the treatment of hepatitis, select the routine clinical observation of hepatitis 400 of making a definite diagnosis.
Patient is divided into two groups for the treatment of first group and contrast second groups at random, treatment first group 200 examples, male's 99 examples wherein, women's 101 examples, 40～72 years old age, 53.1 years old mean age, the shortest person of the course of disease 10 months, elder 22 years, average 10.8 years; Contrast second group 200 examples, male's 97 examples wherein, women's 103 examples, 41～70 years old age, 52.5 years old mean age, the shortest person of the course of disease 9 months, elder 21 years, average 9.8 years.
The course of disease, the degrees of symptoms for the treatment of first group and two groups of cases of contrast second group are basically identical,, without significant difference, have comparability.
2, medicament selection:
Treatment first group is taken medicine of the present invention, oral 3 times of every day, each 2, warm water delivery service after meal; 10 days is 1 course for the treatment of, and take effect common 2 courses for the treatment of, 3～4 recoveries from illness course for the treatment of.
Contrast second group injection aspartic acid magnesium injection liquid, intravenous drip, a 10～20ml, add in 5% glucose injection 250ml or 500ml and slowly instil, every day 1 time, or follow the doctor's advice; 40 days is a course for the treatment of, and take effect 2 courses for the treatment of, and the person of being in a bad way is usually invalid.
3, efficacy determination:
(1) cure: hepatitis symptom disappears, and physical recovery is normal on inspection.
(2) produce effects: basic or most of disappearance of hepatitis symptom, health recovers substantially on inspection.
(3) effective: hepatitis symptom is clearly better or takes a turn for the better, and body part takes a turn for the better on inspection.
(4) invalid: by treating rear hepatitis symptom without being clearly better.
4, result:
Select in the treatment first group of medicine of the present invention, cure 79 examples, produce effects 73 examples, effective 46 examples, invalid 2 examples, cure rate 39.5%, total effective rate 99%.
Cure 31 examples, produce effects 42 examples, effective 49 examples, invalid 78 examples, cure rate 15.5%, total effective rate 61% in contrast second group.
Above result demonstration, the cure rate for the treatment of first group and total effective rate are apparently higher than contrast second group.
Model case is given an example:
1, what certain, the man, 43 years old, people from Datong, suffered from chronic hepatitis, cure the disease and do not heal for many years, Relapse rate, and the time outbreak is arranged, take medicine of the present invention after 2 courses for the treatment of hepatitis thoroughly cure, follow up a case by regular visits to, do not recur again so far.
2, Bai, the female, 51 years old, people from Baoding, suffered from hepatitis C, and cardinal symptom has: detest oil, inappetence, weak, lazy moving, low grade fever, take medicine of the present invention and cure 3 courses for the treatment of, liver function recovery is normal.
3, high certain, the man, 60 years old, people from Changchun, Jilin, suffer from acute icterohepatitisshock, the mobility of thrombinogen is lower than 40%, and serum bilirubin and alaninyl transferring enzyme are high, with above-mentioned Drug therapy after 1 course for the treatment of, the mobility of thrombinogen, serum bilirubin and alaninyl transferring enzyme all recover normal value, after healing, no longer recurrence, follow up a case by regular visits to, and do not recur so far again.
4, Cai, the female, 71 years old, people from Shenyang, Liaoning, suffering from liver cirrhosis, be unable to leave the bed, and takes medicine of the present invention and namely cure 3 courses for the treatment of, and liver function recovery is normal.
Claims (5)
1. medicine for the treatment of hepatitis is characterized in that: the raw material of making described effective ingredient forms and parts by weight are:
42～67 parts of 46～72 parts of Spora Lygodii of 47～72 parts of Alumens of 52～77 parts of Rhizoma Iridis Japonicaes of Folium Malloti Apeltae
32～53 parts of 34～57 parts of Oletum Trogopteroris of 37～62 portions of Herba Desmodii Triquetri (Herba Tadehagi Triquetri)s of 38～65 parts of Herba senecionis nemorensis of Folium et Cacumen Salicis Matsudanae
27～40 parts of 27～47 parts of Radix Hypecol Erecti of 26～45 portions of Cortex Phellodendris of 29～49 parts of Cyrtomium fortunei J. Sm.s of Herba Artemisiae Japonicae
7～27 parts of 17～32 parts of Fructus Akebiaes of 19～36 parts of Carapax Trionycis of 22～37 parts of Cycas revoluta Thunb.s of Fructus Corni.
2. a kind of medicine for the treatment of hepatitis according to claim 1 is characterized in that: the raw material of making described effective ingredient forms and parts by weight are:
47～64 parts of 48～67 parts of Spora Lygodii of 52～69 parts of Alumens of 57～72 parts of Rhizoma Iridis Japonicaes of Folium Malloti Apeltae
36～50 parts of 37～54 parts of Oletum Trogopteroris of 41～57 portions of Herba Desmodii Triquetri (Herba Tadehagi Triquetri)s of 42～62 parts of Herba senecionis nemorensis of Folium et Cacumen Salicis Matsudanae
28～37 parts of 30～42 parts of Radix Hypecol Erecti of 32～44 portions of Cortex Phellodendris of 35～47 parts of Cyrtomium fortunei J. Sm.s of Herba Artemisiae Japonicae
10～24 parts of 20～27 parts of Fructus Akebiaes of 22～32 parts of Carapax Trionycis of 25～34 parts of Cycas revoluta Thunb.s of Fructus Corni.
3. a kind of medicine for the treatment of hepatitis according to claim 1 is characterized in that: the raw material of making described effective ingredient forms and parts by weight are:
50～60 parts of 52～62 parts of Spora Lygodii of 57～63 parts of Alumens of 62～67 parts of Rhizoma Iridis Japonicaes of Folium Malloti Apeltae
40～47 parts of 42～52 parts of Oletum Trogopteroris of 44～52 portions of Herba Desmodii Triquetri (Herba Tadehagi Triquetri)s of 47～57 parts of Herba senecionis nemorensis of Folium et Cacumen Salicis Matsudanae
31～34 parts of 32～37 parts of Radix Hypecol Erecti of 35～42 portions of Cortex Phellodendris of 37～43 parts of Cyrtomium fortunei J. Sm.s of Herba Artemisiae Japonicae
12～19 parts of 22～24 parts of Fructus Akebiaes of 26～29 parts of Carapax Trionycis of 27～32 parts of Cycas revoluta Thunb.s of Fructus Corni.
4. a kind of medicine for the treatment of hepatitis according to claim 1 is characterized in that: the raw material of making described effective ingredient forms and parts by weight are:
55 parts of 57 parts of Spora Lygodii of 60 parts of Alumens of 65 parts of Rhizoma Iridis Japonicaes of Folium Malloti Apeltae
43 parts of 47 parts of Oletum Trogopteroris of 48 portions of Herba Desmodii Triquetri (Herba Tadehagi Triquetri)s of 52 parts of Herba senecionis nemorensis of Folium et Cacumen Salicis Matsudanae
32 parts of 35 parts of Radix Hypecol Erecti of 38 portions of Cortex Phellodendris of 40 parts of Cyrtomium fortunei J. Sm.s of Herba Artemisiae Japonicae
15 parts of 23 parts of Fructus Akebiaes of 27 parts of Carapax Trionycis of 30 parts of Cycas revoluta Thunb.s of Fructus Corni.
5. preparation method as the medicine for the treatment of hepatitis as described in claim 1～4 any one is characterized in that: comprise following processing step:
(1) Alumen, Radix Hypecol Erecti, Fructus Corni and Cycas revoluta Thunb. are mixed, carry out pulverization process after mix homogeneously, grind into powder, cross 120 order fine powders, standby;
(2) Rhizoma Iridis Japonicae, Spora Lygodii, Folium et Cacumen Salicis Matsudanae, Herba senecionis nemorensis, Herba Artemisiae Japonicae, Cyrtomium fortunei J. Sm., Cortex Phellodendri and Fructus Akebiae are cleaned, put into container, add the distilled water of 8～12 times of amounts, soak after 4～5 hours, boiled 3～4 hours, extract; Again add 6～8 times of amount distilled water, boiled 2～3 hours, extract; Finally, add 4～6 times of amount distilled water, heated and boiled 1～2 hour, extract; Merge three times extracting solution, filter, obtain filtrate, be condensed into 50 ℃ of lower relative densities and be 1.10～1.14 thick paste, standby;
(3) Folium Malloti Apeltae is cleaned, chopping, put into container, strand juice, and filter impurity, stay juice standby;
(4) Oletum Trogopterori is put a pot interior little stir-fry, sprayed rice vinegar, then fry to little and do, take out when surface is slightly glossy, dry, grind into powder, cross 200 order fine powders, standby;
(5) Herba Desmodii Triquetri (Herba Tadehagi Triquetri) is cleaned, immersed 85% the alcohol solution dipping 1～2 hour of 5 times of amounts, heating extraction 3 hours, reclaim ethanol, filters, and under 60 ℃ of environment of filtrate simmer down to, the thick paste of relative density 1.20～1.25, standby;
(6) sandy soil are put heating in pot, loose to sandy soil, get Carapax Trionycis and put into pot and fry to the little yellow of epidermis, take out sieve and remove sandy soil, put into the vinegar basin and slightly soak, every 100 jin with 30 jin of vinegar, taking-up is dried, and grinds into powder, crosses 160 order fine powders, and is standby;
(7) fine powder that above-mentioned steps (1)～(6) are made, thick paste and juice mix, and add adjuvant, utilize modern advanced pharmacy science and technology, make capsule, both the medicine for the treatment of hepatitis of the present invention.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103845583A (en) * | 2014-03-19 | 2014-06-11 | 张继莲 | Traditional Chinese medicine preparation for treating chronic hepatitis and preparation method |
| CN105920380A (en) * | 2016-04-13 | 2016-09-07 | 林家希 | Repair traditional Chinese medicine used for treating blood cell infected by flaviviridae |
| CN106924321A (en) * | 2015-12-30 | 2017-07-07 | 姚萍 | Application of the Artemisia japonica in the medicine for preparing treatment virus B hepatitis |
| CN115212253A (en) * | 2022-08-05 | 2022-10-21 | 南京中医药大学 | Chinese herbal compound preparation for treating hepatic fibrosis and preparation method and application thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101069728A (en) * | 2007-06-20 | 2007-11-14 | 文建春 | Chinese medicine composition for treating chronic hepatitis B and preparing method |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101069728A (en) * | 2007-06-20 | 2007-11-14 | 文建春 | Chinese medicine composition for treating chronic hepatitis B and preparing method |
Non-Patent Citations (1)
| Title |
|---|
| 肖朝阳等: "酒精性肝病中医药研究进展", 《河南中医》 * |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103845583A (en) * | 2014-03-19 | 2014-06-11 | 张继莲 | Traditional Chinese medicine preparation for treating chronic hepatitis and preparation method |
| CN103845583B (en) * | 2014-03-19 | 2016-03-30 | 张继莲 | A kind of Chinese medicine preparation and preparation method for the treatment of chronic hepatitis |
| CN106924321A (en) * | 2015-12-30 | 2017-07-07 | 姚萍 | Application of the Artemisia japonica in the medicine for preparing treatment virus B hepatitis |
| CN105920380A (en) * | 2016-04-13 | 2016-09-07 | 林家希 | Repair traditional Chinese medicine used for treating blood cell infected by flaviviridae |
| CN115212253A (en) * | 2022-08-05 | 2022-10-21 | 南京中医药大学 | Chinese herbal compound preparation for treating hepatic fibrosis and preparation method and application thereof |
| CN115212253B (en) * | 2022-08-05 | 2023-04-11 | 南京中医药大学 | Chinese herbal compound preparation for treating hepatic fibrosis and preparation method and application thereof |
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