CN103393800B - Traditional Chinese medicine for treating spleen and stomach heat-wet caused reflux esophagitis - Google Patents
Traditional Chinese medicine for treating spleen and stomach heat-wet caused reflux esophagitis Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine for treating spleen and stomach heat-wet caused reflux esophagitis. The traditional Chinese medicine is prepared from herb of stickyhair pearleverlasting, stellaria aquatic, pogostemon, isatis root, coptis, sweet wormwood, cape jasmine, heterolamium debile, phoenix tree seed and fleece-flower root. The traditional Chinese medicine can be clinically used for treating spleen and stomach heat-wet caused reflux esophagitis.
Description
Technical field
The invention belongs to technical field of Chinese medicines, especially relate to a kind of Chinese medicine for the treatment of spleen and stomach damp-heat type reflux esophagitis.
Background technology
Reflux esophagitis (reflux esophagitis, RE) refers to that abnormal reflux to the esophagus of gastric content causes chronic sympton and (or) tissue injury, shows as typically heartburn and acid regurgitation symptom and Esophageal Mucosa breakage performance.Belong to gastroesophageal reflux disease (gastroesophagesl reflux diseases, GERD) category, typically reflux symptom in the esophagus such as heartburn, acid regurgitation can be had, also can have sore throat, cough, the esophagus such as asthma shows outward.Doctor trained in Western medicine mainly by gastric acid secretion inhibiting, improve gastric motility etc. and treat, majority can only improve clinical symptoms, easily recurs after drug withdrawal, and Long-term taking medicine has again certain side effect.Long-term practice through inventor draws, Chinese medicine is controlled spleen and stomach damp-heat type reflux esophagitis and had better effect, obtains good effect.
Summary of the invention
The object of the present invention is to provide that a kind of therapeutic effect is good, effective percentage is high, Chinese medicine to the treatment spleen and stomach damp-heat type reflux esophagitis of human non-toxic's side effect.
The object of the present invention is achieved like this, according to Chinese medical theory, utilizing the property of medicine of Chinese medicine uniqueness, adopting Herba Clematidis Meyenianae, Herba Cucubali japonici, Herba Pogostemonis, Radix Isatidis, Rhizoma Coptidis, Herba Artemisiae Annuae, Fructus Gardeniae, Heterolamium debile, Semen Firmianae, Radix Polygoni Multiflori according to certain compatibility requirement, through being processed into.
Prepare Chinese medicine of the present invention to be made up of following raw material medicaments: Herba Clematidis Meyenianae 35-45 part, Herba Cucubali japonici 25-35 part, Herba Pogostemonis 20-30 part, Radix Isatidis 20-30 part, Rhizoma Coptidis 15-25 part, Herba Artemisiae Annuae 15-25 part, Fructus Gardeniae 10-20 part, Heterolamium debile 10-20 part, Semen Firmianae 8-15 part, Radix Polygoni Multiflori 8-15 part.
Optimum weight part of raw material of Chinese medicine medicine of the present invention is: Herba Clematidis Meyenianae 40 parts, Herba Cucubali japonici 30 parts, Herba Pogostemonis 25 parts, Radix Isatidis 25 parts, Rhizoma Coptidis 18 parts, Herba Artemisiae Annuae 22 parts, Fructus Gardeniae 18 parts, Heterolamium debile 18 parts, Semen Firmianae 12 parts, Radix Polygoni Multiflori 12 parts.
The pharmacological action of Chinese medicine of the present invention is as follows:
Herba Clematidis Meyenianae: pungent, micro-hardship, cool.Clearing away heat-damp and promoting diuresis, cough-relieving.For anemopyretic cold, tonsillitis, tracheitis, acute gastroenteritis, the diseases such as urinary tract infection.
Herba Cucubali japonici: light, flat.Inducing diuresis for treating stranguria syndrome, promoting the circulation of QI to relieve pain, the continuous wound of synthetism.For pyretic stranguria, stranguria caused by urinary stone, stranguria with blood, wet cloudy stagnation of QI gastral cavity, abdominal distention and pain, the diseases such as traumatic pain.
Herba Pogostemonis: pungent, tepor.Return spleen, stomach, lung meridian.Removing dampness by means of aromatics, stomach function regulating preventing or arresting vomiting, dispelling summer-heat from superficies of the body.
Radix Isatidis: bitter, cold.Return liver, stomach warp.Heat-clearing and toxic substances removing, removing heat from blood sore-throat relieving.For maculae caused by violent heat pathogen, high heat headache, major part pestilence, scarlet fever, erysipelas, mumps, sore throat, skin ulcer is swollen.
Rhizoma Coptidis: bitter, cold.GUIXIN, liver, stomach, large intestine channel.Clearing away heat-fire, dampness, removing toxic substances.Clinical in having loose bowels, dysentery, pathopyretic ulcer, gingival swelling and pain, aphtha of the mouth and tongue, the diseases such as burn and scald.
Herba Artemisiae Annuae: bitter, micro-pungent, cold.Return liver, gallbladder meridian.Heat clearing away, expelling summer-heat, except steaming, preventing the attack (or recurrence) of malaria.For summer-heat, heat-damp in summer, fever due to yin deficiency, malaria, the diseases such as jaundice.
Fructus Gardeniae: bitter, cold, GUIXIN, liver, lung, stomach warp.Clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body., sore swollen toxin unhappy for calentura.
Heterolamium debile: pungent, bitter, cool.Regulating qi-flowing for harmonizing stomach, heat-clearing and toxic substances removing.Gastropyretic vomiting, skin ulcer swells, the puckery pain of pyretic stranguria, the diseases such as menoxenia.Semen Firmianae: sweet, flat.GUIXIN, lung, stomach warp.Pleasant stomach function regulating, strengthening the spleen to promote digestion, hemostasis.For gastralgia, diarrhoea of getting ill from overeating, hernia, early whitening of beard and hair, the diseases such as oral aphthae in children.
Radix Polygoni Multiflori: bitter, sweet, puckery, warm.Return liver, kidney channel.Nourishing the blood and yin, loosening bowel to relieve constipation, preventing the attack (or recurrence) of malaria, dispels the wind, removing toxic substances.Clinical in blood deficiency Light-headedness, cardiopalmus, insomnia, the soreness of the waist and knees of the hepatic and renal YIN deficiency, early whitening of beard and hair, tinnitus, seminal emission, dryness of the intestine constipation,
Chronic malaria body is empty, rubella pruritus, carbuncle sore, scrofula, the diseases such as hemorrhoid.
Spleen and stomach damp-heat type reflux esophagitis belongs to the disease categories such as the acid regurgitation of Chinese medicine, the thoracic obstruction, noisy, stomachache, regurgitation, feeling of fullness, globus hystericus.How because of caused by eating and drinking without temperance, disorder of emotion impairing the spleen and stomach, mostly being caused by stagnation of liver-QI with deficiency of the spleen, stagnated QI transforming into fire, liver-fire invading the stomach, stomach-QI being unable to descend normally, is the card of deficiency in origin and excess in superficiality, coldheat complex.Herba Clematidis Meyenianae clearing away heat-damp and promoting diuresis of the present invention, be monarch drug, Herba Cucubali japonici inducing diuresis for treating stranguria syndrome, Herba Pogostemonis removing dampness by means of aromatics, stomach function regulating preventing or arresting vomiting, for ministerial drug, Radix Isatidis, Rhizoma Coptidis heat-clearing and toxic substances removing, pathogenic fire purging, Herba Artemisiae Annuae heat clearing away, expelling summer-heat, Fructus Gardeniae clearing away heat-damp and promoting diuresis, the pleasant stomach function regulating of Semen Firmianae, strengthening the spleen to promote digestion, Radix Polygoni Multiflori dispels the wind, detoxify.All medicines share, altogether long memorial liver and clearing heat, the merit of circulation of qi promoting dehumidifying, reach effect for the treatment of spleen and stomach damp-heat type reflux esophagitis.
Chinese medicine of the present invention was in 2008 to 2011 the routine patients of clinical observation spleen and stomach damp-heat type reflux esophagitis 88, and clinical report is as follows:
1, physical data
In 88 routine patients, in age 24-66 year, the course of disease is many at 3 months to 5 years, 41 years old mean age.
2, diagnostic criteria
" Chinese medical disease Standardization of diagnosis and curative effect " that diagnosis basis State Administration of Traditional Chinese Medicine issues:
(1) reflux symptom is had;
(2) performance of spleen and stomach damp-heat type reflux esophagitis may be had under scope;
(3) patient has causalgia after typical breastbone, heartburn, acid regurgitation symptom.
Get rid of stomach and esophageal surgery history, esophagostenosis, upper digestive tract malignant change, constitutional dyskinesis, serious accompanying diseases, anemia of pregnant woman and breast-feeding female.
Tcm clinical practice symptom: heartburn, breastbone or precordial region burn sample pain; Acid regurgitation, belch are very then vomitted; Being irritable and getting angry easily, distending pain over the hypochondrium, yellow fur or greasy, the red stringy pulse of matter or stringy and rapid pulse.
3, Therapeutic Method
3.1 prescriptions: Herba Clematidis Meyenianae 40g, Herba Cucubali japonici 30g, Herba Pogostemonis 25g, Radix Isatidis 25g, Rhizoma Coptidis 18g, Herba Artemisiae Annuae 22g, Fructus Gardeniae 18g, Heterolamium debile 18g, Semen Firmianae 12g, Radix Polygoni Multiflori 12g.
3.2 methods of preparation and use: said medicine routinely technique makes decoction, every day 1 dose, every day 2 times 30 days was 1 course for the treatment of.
4, therapeutic outcome:
4.1 formulate with reference to " Chinese medical disease Standardization of diagnosis and curative effect ":
Cure: symptom disappears completely, the erosion of gastroscope check Esophageal Mucosa disappears or substantially disappears;
Effective: symptom is clearly better or substantially disappears, gastroscope check Esophageal Mucosa erosion disappearance more than 1/2 person;
Invalid: symptom is improved not obvious, Esophageal Mucosa erosion disappearance less than 1/2 person under gastroscope.
4.2 results: in 88 routine patients, clinical cure 65 example, effective 15 examples, invalid 8 examples, total effective rate is 90.9%.
5, model case
5.1 Liu, man, 33 years old.Pain is burnt in gastral cavilty portion, companion's acid regurgitation recurrent exerbation 4 years.Often certainly take omeprazole and domperidone during outbreak, i.e. drug withdrawal after disease amelioration, hold a sinecure time serious burn feeling, nausea and vomiting, and lack of appetite is indigestion and loss of appetite, food postemphasis.Gastroscopy is shown in that stomach and Esophageal Mucosa are slightly rotten to the corn, and biopsy epithelium degeneration necrosis, has no tumor and ulcer, meet reflux esophagitis.Examine its wiry and frequent pulse, body of the tongue is light red, yellow and thin fur, is diagnosed as spleen and stomach damp-heat type reflux esophagitis.Take medicine of the present invention, treat 1 course for the treatment of, symptom obviously alleviates, and continues to take 2 courses for the treatment of, and recovery from illness, follows up a case by regular visits to and have no recurrence in 6 months.
5.2 Zhangs, man, 42 years old, readme suffered from gastropathy for many years, recently owing to feeling bad, swollen, scorching hot, the retrosternal pain in sensation gastral cavilty top, and with pantothenic acid, heartburn, xerostomia, bitter taste, drink water more, receive can, constipation with dry stool, sleeps not peaceful night.Red tongue, Artemusia lactiflora Wall. is thin, thready and stringy pulse.Gastroscopy on the same day: chronic atrophic gastritis companion gastric antrum erosion, spleen and stomach damp-heat type reflux esophagitis II level.Take medicine of the present invention, every day 1 dose, after 1 course for the treatment of, symptom is clearly better, and continues to take 2 courses for the treatment of, and recovery from illness, follows up a case by regular visits to and have no recurrence in 6 months.
5.3 Jiangs, female, 37 years old, the heartburn acid regurgitation of readme more than 1 year, occurred heartburn without obvious inducement before 1 year, acid regurgitation, felt sick, belch frequency, bitter taste, gastral cavity abdomen fear of cold.Receive can, peace of sleeping, large loose stool is thin, time accompany mucus.Light red tongue, fat, crackle, white and thin fur, deep-rolling pulse carefully delays.Gastroscopy: distal esophagus mucosa is congested, rotten to the corn and ooze out, chronic gastritis.Be diagnosed as spleen and stomach damp-heat type reflux esophagitis.Take medicine of the present invention, every day 1 dose, after 1 course for the treatment of, symptom is clearly better, and continues to take 1 course for the treatment of, and recovery from illness, follows up a case by regular visits to and have no recurrence in 6 months.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further illustrated, and this embodiment following does not only limit the present invention for illustration of the present invention.
Embodiment 1, a kind of Chinese medicine for the treatment of spleen and stomach damp-heat type reflux esophagitis is made up of Herba Clematidis Meyenianae 35g, Herba Cucubali japonici 25g, Herba Pogostemonis 20g, Radix Isatidis 20g, Rhizoma Coptidis 15g, Herba Artemisiae Annuae 15g, Fructus Gardeniae 10g, Heterolamium debile 10g, Semen Firmianae 8g, Radix Polygoni Multiflori 8g.
Embodiment 2, a kind of Chinese medicine for the treatment of spleen and stomach damp-heat type reflux esophagitis is made up of Herba Clematidis Meyenianae 40g, Herba Cucubali japonici 30g, Herba Pogostemonis 25g, Radix Isatidis 25g, Rhizoma Coptidis 18g, Herba Artemisiae Annuae 22g, Fructus Gardeniae 18g, Heterolamium debile 18g, Semen Firmianae 12g, Radix Polygoni Multiflori 12g.
Embodiment 3, a kind of Chinese medicine for the treatment of spleen and stomach damp-heat type reflux esophagitis is made up of Herba Clematidis Meyenianae 45g, Herba Cucubali japonici 35g, Herba Pogostemonis 30g, Radix Isatidis 30g, Rhizoma Coptidis 25g, Herba Artemisiae Annuae 25g, Fructus Gardeniae 20g, Heterolamium debile 20g, Semen Firmianae 15g, Radix Polygoni Multiflori 15g.
Claims (2)
1. treat a Chinese medicine for spleen and stomach damp-heat type reflux esophagitis, it is characterized in that it is made up of following raw material medicaments:
Herba Clematidis Meyenianae 35-45 part, Herba Cucubali japonici 25-35 part, Herba Pogostemonis 20-30 part, Radix Isatidis 20-30 part, Rhizoma Coptidis 15-25 part, Herba Artemisiae Annuae 15-25 part, Fructus Gardeniae 10-20 part, Heterolamium debile 10-20 part, Semen Firmianae 8-15 part, Radix Polygoni Multiflori 8-15 part.
2. Chinese medicine according to claim 1, is characterized in that it is made up of following raw material medicaments:
Herba Clematidis Meyenianae 40 parts, Herba Cucubali japonici 30 parts, Herba Pogostemonis 25 parts, Radix Isatidis 25 parts, Rhizoma Coptidis 18 parts, Herba Artemisiae Annuae 22 parts, Fructus Gardeniae 18 parts, Heterolamium debile 18 parts, Semen Firmianae 12 parts, Radix Polygoni Multiflori 12 parts.
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