CN104436080A - Traditional Chinese medicine for treating dampness-heat middle energizer type cardia achalasia - Google Patents

Traditional Chinese medicine for treating dampness-heat middle energizer type cardia achalasia Download PDF

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CN104436080A
CN104436080A CN201510000426.1A CN201510000426A CN104436080A CN 104436080 A CN104436080 A CN 104436080A CN 201510000426 A CN201510000426 A CN 201510000426A CN 104436080 A CN104436080 A CN 104436080A
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chinese medicine
radix
achalasia
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郄美莲
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282Artemisia, e.g. wormwood or sagebrush
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/29Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/45Ericaceae or Vacciniaceae (Heath or Blueberry family), e.g. blueberry, cranberry or bilberry
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9066Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration

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Abstract

The invention relates to a traditional Chinese medicine for treating dampness-heat middle energizer type cardia achalasia. The traditional Chinese medicine comprises artemisia eriopoda, craibiodendron stellatum roots, veronica linariifolia, radix curcumae, rhizoma atractylodis, rattletop, Chinese mahonia stems, pawpaw, all-grass or roots of fourangular crotalaria and tuber cubeba. The traditional Chinese medicine can be used for treating the dampness-heat middle energizer type cardia achalasia in clinic.

Description

A kind of Chinese medicine for the treatment of damp and hot middle resistance type achalasia of cardia
Technical field
The invention belongs to technical field of Chinese medicines, especially relate to a kind of Chinese medicine for the treatment of damp and hot middle resistance type achalasia of cardia.
Background technology
Esophagus-achalasia of cardia, due to esophagus delayed ischemic neurological deficits, esophagus lacks wriggles, LES high pressure and when swallowing in lose slow state, so that food is difficult to successfully enter stomach and be stranded in esophagus, and make esophagectasia, prolongation or bending a kind of disease, easily cause Esophagus Function to block, clinical have the performance such as dysphagia, anti-food, chest pain, and the many spiritednesses of its premorbid stimulate medical history.Modern medicine thinks that this sick protracted course of disease has concurrent canceration possibility, therefore should active treatment to this disease.And modern medicine is except doing except symptomatic treatment with nitroglycerin, mainly rely on surgical operation therapy, but have the possibility of concurrent ER, gastroesophageal reflux, not easily accepted by patient.Damp and hot middle resistance type achalasia of cardia clinical symptoms is: chest pain, bitter taste in the mouth and dry throat, regurgitation of feeling sick, physical fatigue and lassitude of spirit, yellowish fur, slippery and rapid pulse.The damp and hot middle resistance type achalasia of cardia of the treatment by Chinese herbs that the present invention prepares, achieves good effect.
Summary of the invention
The object of the present invention is to provide that a kind of therapeutic effect is good, effective percentage is high, Chinese medicine to the damp and hot middle resistance type achalasia of cardia of the treatment of human non-toxic's side effect.
The object of the present invention is achieved like this, according to Chinese medical theory, utilizes the property of medicine of Chinese medicine uniqueness, adopts Artemisia eriopoda Bunge., Radix Craibiodendri, HERBA VERONICAE DILATATAE, Radix Curcumae, Rhizoma Atractylodis, Rhizoma Cimicifugae, Caulis Mahoniae, Fructus Chaenomelis, Herba sei Radix Crotalariae tetragonae, Fructus Litseae, according to certain compatibility requirement, through being processed into.
Prepare Chinese medicine of the present invention to be made up of following raw material medicaments: Artemisia eriopoda Bunge. 35-45 part, Radix Craibiodendri 25-35 part, HERBA VERONICAE DILATATAE 25-35 part, Radix Curcumae 15-20 part, Rhizoma Atractylodis 15-20 part, Rhizoma Cimicifugae 15-20 part, Caulis Mahoniae 15-20 part, Fructus Chaenomelis 10-15 part, Herba sei Radix Crotalariae tetragonae 10-15 part, Fructus Litseae 2-5 part.
Optimum weight part of raw material of Chinese medicine medicine of the present invention is: Artemisia eriopoda Bunge. 40 parts, Radix Craibiodendri 30 parts, HERBA VERONICAE DILATATAE 30 parts, Radix Curcumae 18 parts, Rhizoma Atractylodis 18 parts, Rhizoma Cimicifugae 18 parts, Caulis Mahoniae 18 parts, Fructus Chaenomelis 18 parts, Herba sei Radix Crotalariae tetragonae 12 parts, Fructus Litseae 3 parts.
The pharmacological action of Chinese medicine of the present invention is as follows:
Artemisia eriopoda Bunge.: bitter, micro-pungent, cool.Wind and heat dispersing, removing damp and stopping pain.For headache due to pathogenic wind-heat, rheumatic arthritis, the diseases such as venom.
Radix Craibiodendri: pungent, bitter, flat.Return liver, kidney channel.Wind-damp dispelling, removing obstruction in the collateral to relieve pain.For rheumatic arthralgia, traumatic injury.
HERBA VERONICAE DILATATAE: bitter, cold.Heat-clearing and toxic substances removing, preventing phlegm from forming and stopping coughing.For cough due to lung-heat, lung abscess, skin eczema, the diseases such as rubella pruritus.
Radix Curcumae: bitter, acrid, cold, returns liver, gallbladder, heart channel.Blood-activating and qi-promoting pain relieving, resolving depression clears away heart-fire, promoting the function of the gallbladder to alleviate jaundice, removing heat from blood.For the card of calentura coma, epilepsy unconsciousness due to blockage of phlegm.
Rhizoma Atractylodis: acrid, bitter, warm, return spleen, stomach warp.Drying damp and strengthening spleen, wind-damp dispelling.For card burnt in humidity hysteresis, rheumatism arthromyodynia, affection of exogenous wind-cold holds wet exterior syndrome under the arm.
Rhizoma Cimicifugae: pungent, sweet, be slightly cold, returns lung, spleen, stomach, large intestine channel.Deliver rash, heat-clearing and toxic substances removing, elevate a turnable ladder yang-energy.For headache due to pathogenic wind-heat, measles without adequate eruption, laryngopharynx swelling and pain, collapse of QI, chronic diarrhea proctoptosis, metrostaxis etc.
Caulis Mahoniae: bitter, cold in nature.Return large intestine, lung, kidney channel.Heat clearing away, dampness, removing toxic substances.Cure mainly cough due to lung-heat, jaundice, have loose bowels, dysentery, conjunctival congestion and swelling pain, skin infection, eczema, scald.
Fructus Chaenomelis: sour, warm, returns liver, spleen channel.Relaxing muscles and tendons and activating QI and blood in the collateral, dehumidifying stomach function regulating.Cure mainly rheumatic arthralgia, the contracture of muscle arteries and veins, beriberi swells and ache, convulsion etc. of vomiting and diarrhoea.
Herba sei Radix Crotalariae tetragonae: pungent, micro-bitterness, cool temperature.Return stomach, large intestine, small intestine meridian.Heat-clearing and toxic substances removing, dampness removing is treating stranguria, promoting the circulation of QI to relieve pain.Clinical in jaundice, pyretic stranguria, vesical calculus, stomachache, mass in the abdomen such as not to disappear the disease.
Fructus Litseae: pungent, warm.Return spleen, kidney, stomach, urinary bladder channel.Warming spleen and stomach for dispelling cold, promoting the circulation of QI to relieve pain, warming the kidney.Clinical in cold syndrome of the stomach vomiting, distension and fullness in the abdomen cold type of pain, increased borborygmus and diarrhea, colic of cold type is suffered from abdominal pain, and cold-damp dribbling urination muddiness waits disease.
According to the Clinical symptoms of achalasia of cardia and esophagus, this disease should belong to the category such as Chinese medicine " card of choking ", " regurgitation ", " stomachache ".Pathomechanism is liver dysfunction of spleen and stomach, cause taste mechanism of qi to block so that taste deficient, elevating function is abnormal.Artemisia eriopoda Bunge. wind and heat dispersing in the present invention, removing damp and stopping pain, for monarch drug, Radix Craibiodendri wind-damp dispelling, dredging collateral, HERBA VERONICAE DILATATAE heat-clearing and toxic substances removing, preventing phlegm from forming and stopping coughing, for ministerial drug, Radix Curcumae blood-activating and qi-promoting, resolving depression clears away heart-fire, Rhizoma Atractylodis are drying damp and strengthening spleen, wind-damp dispelling, Rhizoma Cimicifugae detoxifies, elevate a turnable ladder yang-energy, Caulis Mahoniae heat clearing away, dampness, removing toxic substances, Fructus Chaenomelis relaxing muscles and tendons and activating QI and blood in the collateral, dehumidifying stomach function regulating, Herba sei Radix Crotalariae tetragonae heat-clearing and toxic substances removing, circulation of qi promoting, Fructus Litseae warming spleen and stomach for dispelling cold, promoting the circulation of QI to relieve pain, all medicine compatibilities use above, play removing damp-heat altogether, Tongluo Jiedu, effect of relieving QI stagnancy in the stomach, reach the object for the treatment of damp and hot middle resistance type achalasia of cardia.
Chinese medicine of the present invention is used in 2006 to 2014 the routine patients of the damp and hot middle resistance type achalasia of cardia disease 66 of clinical observation, and clinical report is as follows:
1, physical data
In 66 routine patients, women 36 example, male 30 example, at minimum 20 years old of age, maximum 65 years old, the course of disease was many at 3-17 month.
2, diagnostic criteria
With reference to " Chinese medical disease Standardization of diagnosis and curative effect ":
Clinical manifestation to be choked difficult purgation sense or intermittent non-Progressive symmetric erythrokeratodermia dysphagia for there being stalk after conscious breastbone when swallowing food, and the state of an illness can increase and decrease with emotion changes, or with regurgitation of food and retrosternal pain.X-ray barium meal examination esophagus is obviously expanded and is extended and bend, and without peristalsis, distal esophagus is to pars cardiaca 1 ~ 3cm section symmetrically type infundibular stenosis, and mucosal pattern is normal, and stomach bottom is abnormal without other.Gastroscopy esophagus is obviously expanded.Narrow ringwise at the visible esophageal lumen of distal esophagus of expansion, smooth mucosal, without infiltrating under mucosa, and gets rid of scleroderma, amyloidosis, the diseases such as tumor.
Damp and hot middle resistance type achalasia of cardia clinical symptoms is: chest pain, bitter taste in the mouth and dry throat, regurgitation of feeling sick, physical fatigue and lassitude of spirit, yellowish fur, slippery and rapid pulse.
3, Therapeutic Method
3.1 prescriptions: Merremia yunnanensis 35g, Folium Rhododendri Anthopogonoidis 25g, HERBA VERONICAE DILATATAE 25g, Exocarpium Citri Grandis 18g, Semen Plantaginis 18g, Caulis Polygoni Multiflori 18g, Radix Astragali 18g, Radix Peucedani 18g, fruit-rind of Chinese trichosanthes 12g, Flos daphnes odorae 7g.
3.2 preparation methoies: said medicine routinely technique makes decoction.
3.3 instructions of taking: each 1 dose, every day 2 times 4 weeks was 1 course for the treatment of.
4, therapeutic outcome:
4.1 with reference to " Chinese medical disease Standardization of diagnosis and curative effect ":
Cure: clinical symptom disappearance, barium meal radioscopy takes the photograph sheet and gastroscopy obviously recovers normal;
Take a turn for the better: clinical symptoms is improved, and X-ray or gastroscopy are clearly better;
Do not heal: clinical symptoms and sign are all without improvement.
4.2 results: in 66 routine patients, cure 39 examples (59.1%), 21 examples that take a turn for the better (31.8%), and do not heal 6 examples (9.1%), and total effective rate is 90.9%.
5, model case
5.1 Lu, female, 33 years old.Choking feeling under breastbone during because swallowing food, regurgitation, swallows and has some setbacks, vexed pain after breastbone, and regurgitation of feeling sick, spiritlessness and weakness, anorexia, yellowish fur, rolling pulse, in conjunction with through digestive tract barivm meal fluoroscopy (screem) and gastroscopy, is finally diagnosed as damp and hot middle resistance type achalasia of cardia.Take Chinese medicine of the present invention to treat, after treating 2 courses for the treatment of, all diseases disappear all, peace of sleeping night and, diet two is just all normal, recovery from illness.
5.2 tall certain, man, 42 years old, dysphagia, distending pain after breastbone, vomiting was felt sick, yellowish fur, rolling pulse.In conjunction with digestive tract barivm meal fluoroscopy (screem) and gastroscopy, be diagnosed as damp and hot middle resistance type achalasia of cardia.Taken the Chinese medicine that the present invention treats damp and hot middle resistance type achalasia of cardia, 1 course for the treatment of, symptom obviously alleviates, and continues to take 2 courses for the treatment of, and disease obtains recovery from illness.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further illustrated, and this embodiment following does not only limit the present invention for illustration of the present invention.
Embodiment 1, a kind of Chinese medicine for the treatment of damp and hot middle resistance type achalasia of cardia, it is made up of following raw material medicaments: Artemisia eriopoda Bunge. 45g, Radix Craibiodendri 35g, HERBA VERONICAE DILATATAE 35g, Radix Curcumae 20g, Rhizoma Atractylodis 20g, Rhizoma Cimicifugae 20g, Caulis Mahoniae 20g, Fructus Chaenomelis 15g, Herba sei Radix Crotalariae tetragonae 15g, Fructus Litseae 5g.
Embodiment 2, a kind of Chinese medicine for the treatment of damp and hot middle resistance type achalasia of cardia, it is made up of following raw material medicaments: Artemisia eriopoda Bunge. 40g, Radix Craibiodendri 30g, HERBA VERONICAE DILATATAE 30g, Radix Curcumae 18g, Rhizoma Atractylodis 18g, Rhizoma Cimicifugae 18g, Caulis Mahoniae 18g, Fructus Chaenomelis 18g, Herba sei Radix Crotalariae tetragonae 12g, Fructus Litseae 3g.
Embodiment 3, a kind of Chinese medicine for the treatment of damp and hot middle resistance type achalasia of cardia, it is made up of following raw material medicaments: Artemisia eriopoda Bunge. 35g, Radix Craibiodendri 25g, HERBA VERONICAE DILATATAE 25g, Radix Curcumae 15g, Rhizoma Atractylodis 15g, Rhizoma Cimicifugae 15g, Caulis Mahoniae 15g, Fructus Chaenomelis 10g, Herba sei Radix Crotalariae tetragonae 10g, Fructus Litseae 2g.

Claims (2)

1. treat a Chinese medicine for damp and hot middle resistance type achalasia of cardia, it is characterized in that comprising following crude drug:
Artemisia eriopoda Bunge. 35-45 part, Radix Craibiodendri 25-35 part, HERBA VERONICAE DILATATAE 25-35 part, Radix Curcumae 15-20 part, Rhizoma Atractylodis 15-20 part, Rhizoma Cimicifugae 15-20 part, Caulis Mahoniae 15-20 part, Fructus Chaenomelis 10-15 part, Herba sei Radix Crotalariae tetragonae 10-15 part, Fructus Litseae 2-5 part.
2. Chinese medicine according to claim 1, is characterized in that comprising following crude drug:
Artemisia eriopoda Bunge. 40 parts, Radix Craibiodendri 30 parts, HERBA VERONICAE DILATATAE 30 parts, Radix Curcumae 18 parts, Rhizoma Atractylodis 18 parts, Rhizoma Cimicifugae 18 parts, Caulis Mahoniae 18 parts, Fructus Chaenomelis 18 parts, Herba sei Radix Crotalariae tetragonae 12 parts, Fructus Litseae 3 parts.
CN201510000426.1A 2015-01-04 2015-01-04 Traditional Chinese medicine for treating dampness-heat middle energizer type cardia achalasia Pending CN104436080A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105726951A (en) * 2016-03-24 2016-07-06 曹卿 Traditional Chinese medicine for treating achalasia of cardia caused by deficiency of spleen and stomach

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105726951A (en) * 2016-03-24 2016-07-06 曹卿 Traditional Chinese medicine for treating achalasia of cardia caused by deficiency of spleen and stomach

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Application publication date: 20150325