CN103380479B - 飞行时间型质量分析装置 - Google Patents
飞行时间型质量分析装置 Download PDFInfo
- Publication number
- CN103380479B CN103380479B CN201180068055.0A CN201180068055A CN103380479B CN 103380479 B CN103380479 B CN 103380479B CN 201180068055 A CN201180068055 A CN 201180068055A CN 103380479 B CN103380479 B CN 103380479B
- Authority
- CN
- China
- Prior art keywords
- ion
- reflector
- potential
- time
- electric field
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/26—Mass spectrometers or separator tubes
- H01J49/34—Dynamic spectrometers
- H01J49/40—Time-of-flight spectrometers
- H01J49/405—Time-of-flight spectrometers characterised by the reflectron, e.g. curved field, electrode shapes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/26—Mass spectrometers or separator tubes
- H01J49/34—Dynamic spectrometers
- H01J49/40—Time-of-flight spectrometers
- H01J49/403—Time-of-flight spectrometers characterised by the acceleration optics and/or the extraction fields
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Optics & Photonics (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Electron Tubes For Measurement (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2010-283187 | 2010-12-20 | ||
| JP2010283187 | 2010-12-20 | ||
| PCT/JP2011/079471 WO2012086630A1 (ja) | 2010-12-20 | 2011-12-20 | 飛行時間型質量分析装置 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103380479A CN103380479A (zh) | 2013-10-30 |
| CN103380479B true CN103380479B (zh) | 2016-01-20 |
Family
ID=46313899
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201180068055.0A Active CN103380479B (zh) | 2010-12-20 | 2011-12-20 | 飞行时间型质量分析装置 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US8772708B2 (enExample) |
| EP (2) | EP2669930B1 (enExample) |
| JP (2) | JP5629928B2 (enExample) |
| CN (1) | CN103380479B (enExample) |
| WO (1) | WO2012086630A1 (enExample) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2908329B1 (en) * | 2012-10-10 | 2022-01-12 | Shimadzu Corporation | Time-of-flight mass spectrometer |
| JP6292319B2 (ja) * | 2014-12-24 | 2018-03-14 | 株式会社島津製作所 | 飛行時間型質量分析装置 |
| US10621042B2 (en) * | 2014-12-31 | 2020-04-14 | Pure Storage, Inc. | Vault transformation within a dispersed storage network |
| GB201507363D0 (en) | 2015-04-30 | 2015-06-17 | Micromass Uk Ltd And Leco Corp | Multi-reflecting TOF mass spectrometer |
| GB201520130D0 (en) | 2015-11-16 | 2015-12-30 | Micromass Uk Ltd And Leco Corp | Imaging mass spectrometer |
| GB201520134D0 (en) | 2015-11-16 | 2015-12-30 | Micromass Uk Ltd And Leco Corp | Imaging mass spectrometer |
| GB201520540D0 (en) | 2015-11-23 | 2016-01-06 | Micromass Uk Ltd And Leco Corp | Improved ion mirror and ion-optical lens for imaging |
| JP2017098142A (ja) | 2015-11-26 | 2017-06-01 | 株式会社島津製作所 | イオン照射装置及び該装置を用いた表面分析装置 |
| JP6468370B2 (ja) * | 2016-01-12 | 2019-02-13 | 株式会社島津製作所 | 飛行時間型質量分析装置 |
| JP6346973B2 (ja) * | 2016-04-19 | 2018-06-20 | 亨 絹川 | 飛行時間型質量分析装置 |
| GB201613988D0 (en) | 2016-08-16 | 2016-09-28 | Micromass Uk Ltd And Leco Corp | Mass analyser having extended flight path |
| GB2558221B (en) * | 2016-12-22 | 2022-07-20 | Micromass Ltd | Ion mobility separation exit transmission control |
| GB2567794B (en) | 2017-05-05 | 2023-03-08 | Micromass Ltd | Multi-reflecting time-of-flight mass spectrometers |
| GB2563571B (en) | 2017-05-26 | 2023-05-24 | Micromass Ltd | Time of flight mass analyser with spatial focussing |
| US11817303B2 (en) | 2017-08-06 | 2023-11-14 | Micromass Uk Limited | Accelerator for multi-pass mass spectrometers |
| US11049712B2 (en) | 2017-08-06 | 2021-06-29 | Micromass Uk Limited | Fields for multi-reflecting TOF MS |
| US11081332B2 (en) | 2017-08-06 | 2021-08-03 | Micromass Uk Limited | Ion guide within pulsed converters |
| WO2019030472A1 (en) | 2017-08-06 | 2019-02-14 | Anatoly Verenchikov | IONIC MIRROR FOR MULTI-REFLECTION MASS SPECTROMETERS |
| US11211238B2 (en) | 2017-08-06 | 2021-12-28 | Micromass Uk Limited | Multi-pass mass spectrometer |
| WO2019030476A1 (en) | 2017-08-06 | 2019-02-14 | Anatoly Verenchikov | INJECTION OF IONS IN MULTI-PASSAGE MASS SPECTROMETERS |
| EP3662502A1 (en) | 2017-08-06 | 2020-06-10 | Micromass UK Limited | Printed circuit ion mirror with compensation |
| GB2568354B (en) * | 2017-09-28 | 2022-08-10 | Bruker Daltonics Gmbh & Co Kg | Wide-range high mass resolution in reflector time-of-flight mass spectrometers |
| GB201806507D0 (en) * | 2018-04-20 | 2018-06-06 | Verenchikov Anatoly | Gridless ion mirrors with smooth fields |
| GB201807626D0 (en) | 2018-05-10 | 2018-06-27 | Micromass Ltd | Multi-reflecting time of flight mass analyser |
| GB201807605D0 (en) | 2018-05-10 | 2018-06-27 | Micromass Ltd | Multi-reflecting time of flight mass analyser |
| US11295945B2 (en) | 2018-05-16 | 2022-04-05 | Shimadzu Corporation | Time-of-flight mass spectrometer |
| GB201808459D0 (en) * | 2018-05-23 | 2018-07-11 | Thermo Fisher Scient Bremen Gmbh | Ion front tilt correction for time of flight(tof) mass spectrometer |
| GB201808530D0 (en) | 2018-05-24 | 2018-07-11 | Verenchikov Anatoly | TOF MS detection system with improved dynamic range |
| GB201810573D0 (en) | 2018-06-28 | 2018-08-15 | Verenchikov Anatoly | Multi-pass mass spectrometer with improved duty cycle |
| GB201901411D0 (en) | 2019-02-01 | 2019-03-20 | Micromass Ltd | Electrode assembly for mass spectrometer |
| GB201903779D0 (en) | 2019-03-20 | 2019-05-01 | Micromass Ltd | Multiplexed time of flight mass spectrometer |
| JP7322650B2 (ja) * | 2019-10-11 | 2023-08-08 | 株式会社島津製作所 | マルチターン型飛行時間型質量分析装置及びその製造方法 |
| JP7533393B2 (ja) | 2021-07-21 | 2024-08-14 | 株式会社島津製作所 | 直交加速飛行時間型質量分析装置 |
| CN118862313B (zh) * | 2024-09-24 | 2024-12-06 | 中国空气动力研究与发展中心计算空气动力研究所 | 一种飞行器流场等离子体环境收敛判别方法 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6365892B1 (en) * | 1997-11-24 | 2002-04-02 | Robert J. Cotter | Method and apparatus for correction of initial ion velocity in a reflectron time-of-flight mass spectrometer |
| JP2003151487A (ja) * | 2001-11-09 | 2003-05-23 | Shimadzu Corp | 飛行時間型質量分析装置 |
| CN101366097A (zh) * | 2005-10-11 | 2009-02-11 | 莱克公司 | 具有正交加速的多次发射飞行时间质谱仪 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60119067A (ja) | 1983-11-30 | 1985-06-26 | Shimadzu Corp | 飛行時間型質量分析装置 |
| US5300774A (en) * | 1991-04-25 | 1994-04-05 | Applied Biosystems, Inc. | Time-of-flight mass spectrometer with an aperture enabling tradeoff of transmission efficiency and resolution |
| DE4322101C2 (de) * | 1993-07-02 | 1995-06-14 | Bergmann Thorald | Ionenquelle für Flugzeit-Massenspektrometer |
| US5464985A (en) | 1993-10-01 | 1995-11-07 | The Johns Hopkins University | Non-linear field reflectron |
| AU2622195A (en) * | 1994-05-31 | 1995-12-21 | University Of Warwick | Tandem mass spectrometry apparatus |
| US5942758A (en) * | 1997-09-10 | 1999-08-24 | Bruker Daltronics, Inc. | Shielded lens |
| US6518569B1 (en) * | 1999-06-11 | 2003-02-11 | Science & Technology Corporation @ Unm | Ion mirror |
| DE10005698B4 (de) * | 2000-02-09 | 2007-03-01 | Bruker Daltonik Gmbh | Gitterloses Reflektor-Flugzeitmassenspektrometer für orthogonalen Ioneneinschuss |
| CA2405047C (en) * | 2000-06-28 | 2007-03-27 | The Johns Hopkins University | Time-of-flight mass spectrometer array instrument |
| DE10156604A1 (de) * | 2001-11-17 | 2003-05-28 | Bruker Daltonik Gmbh | Raumwinkelfokussierender Reflektor für Flugzeitmassenspektrometer |
| US6900431B2 (en) * | 2003-03-21 | 2005-05-31 | Predicant Biosciences, Inc. | Multiplexed orthogonal time-of-flight mass spectrometer |
| US6998607B1 (en) * | 2004-08-31 | 2006-02-14 | Thermo Finnigan Llc | Temperature compensated time-of-flight mass spectrometer |
| US20080290269A1 (en) * | 2005-03-17 | 2008-11-27 | Naoaki Saito | Time-Of-Flight Mass Spectrometer |
| US7589319B2 (en) * | 2007-05-01 | 2009-09-15 | Virgin Instruments Corporation | Reflector TOF with high resolution and mass accuracy for peptides and small molecules |
| JP5777062B2 (ja) * | 2009-03-27 | 2015-09-09 | 国立大学法人大阪大学 | イオン源、およびそれを備える質量分析装置 |
-
2011
- 2011-12-20 US US13/996,372 patent/US8772708B2/en active Active
- 2011-12-20 EP EP11851297.9A patent/EP2669930B1/en active Active
- 2011-12-20 CN CN201180068055.0A patent/CN103380479B/zh active Active
- 2011-12-20 EP EP17202314.5A patent/EP3306640B1/en active Active
- 2011-12-20 WO PCT/JP2011/079471 patent/WO2012086630A1/ja not_active Ceased
- 2011-12-20 JP JP2012549822A patent/JP5629928B2/ja active Active
-
2014
- 2014-09-17 JP JP2014188598A patent/JP5924387B2/ja active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6365892B1 (en) * | 1997-11-24 | 2002-04-02 | Robert J. Cotter | Method and apparatus for correction of initial ion velocity in a reflectron time-of-flight mass spectrometer |
| JP2003151487A (ja) * | 2001-11-09 | 2003-05-23 | Shimadzu Corp | 飛行時間型質量分析装置 |
| CN101366097A (zh) * | 2005-10-11 | 2009-02-11 | 莱克公司 | 具有正交加速的多次发射飞行时间质谱仪 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2669930A4 (en) | 2015-12-23 |
| WO2012086630A1 (ja) | 2012-06-28 |
| JP5924387B2 (ja) | 2016-05-25 |
| EP2669930B1 (en) | 2018-02-14 |
| CN103380479A (zh) | 2013-10-30 |
| JP5629928B2 (ja) | 2014-11-26 |
| EP3306640A1 (en) | 2018-04-11 |
| EP3306640B1 (en) | 2024-04-10 |
| EP2669930A1 (en) | 2013-12-04 |
| US8772708B2 (en) | 2014-07-08 |
| US20140054456A1 (en) | 2014-02-27 |
| JP2014241298A (ja) | 2014-12-25 |
| JPWO2012086630A1 (ja) | 2014-05-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| ASS | Succession or assignment of patent right |
Owner name: SHIMADZU SOISAKUSHO LTD. Free format text: FORMER OWNER: NAT UNIVERSITY CORP. KOBE UNIVE Effective date: 20141215 Free format text: FORMER OWNER: SHIMADZU SOISAKUSHO LTD. Effective date: 20141215 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20141215 Address after: Kyoto Japan Applicant after: Shimadzu Corp. Address before: Hyogo Applicant before: Nat University Corp. Kobe Unive Applicant before: Shimadzu Corp. |
|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |