CN103341091B - Traditional Chinese medicine particle designing powder for promoting growth of livestock and poultry as well as preparation method thereof - Google Patents
Traditional Chinese medicine particle designing powder for promoting growth of livestock and poultry as well as preparation method thereof Download PDFInfo
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- CN103341091B CN103341091B CN201310263112.1A CN201310263112A CN103341091B CN 103341091 B CN103341091 B CN 103341091B CN 201310263112 A CN201310263112 A CN 201310263112A CN 103341091 B CN103341091 B CN 103341091B
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Abstract
The invention discloses traditional Chinese medicine particle designing powder for promoting the growth of livestock and poultry as well as a preparation method thereof. The designing powder comprises the following components in parts by weight: 26.5 parts of white atractylodes rhizome, 13.5 parts of immature bitter orange, 27.0 parts of roasted malt, 26.5 parts of Chinese yam and 6.5 parts of lotus leaves, wherein Chinese yam is added for tonifying the spleen, benefiting qi and nourishing yin; roasted malt is added for promoting the circulation of qi, helping digestion, strengthening the spleen and promoting appetite. Based on the synergistic actions of all the components, the powder has the functions of tonifying the spleen and strengthening the stomach for promoting the growth of the livestock and the poultry. The preparation method comprises the following steps of: pertreating medicinal materials; preparing a lotus leaf extract; preparing the fine mixed powder of white atractylodes rhizome, immature bitter orange and lotus leaves; and finally preparing the traditional Chinese medicine particle designing powder. According to the preparation process, the immature bitter orange and the white atractylodes rhizome are crushed conventionally at first; then superfine crushing is performed on Chinese yam and roasted malt; and based on the attraction force among the powders with different particle diameters, the immature bitter orange and atractylodes rhizome medicine powder with large particle diameters is wrapped in the Chinese yam and roasted malt medicine micropowder with small particle diameters. Thus, the flavor is blocked and the volatilization loss of effective components is avoided. Therefore, the stability of the prepared powder is enhanced. As a result, the quality of the traditional Chinese medicine particle designing is stable and controllable.
Description
Technical field
The present invention relates to the technical field that Chinese medicine particle design is loose, particularly relate to and a kind ofly promote the Chinese medicine particle design of growth of animals or poultry loose and preparation method thereof.
Background technology
Domestic livestock and poultry farm is most, and to raise scattered, management level are generally not high, lack relevant raising standardized management and diseases prevention and treatment knowledge, cause the generation of livestock and poultry, dyspeptic situation often has generation, even causes growth of animal slow, causes huge economic loss to raiser.Current growth-promoting class types of drugs is various, comprises antibiotic, hormone, chemical drugs and Chinese herbal and crude drugs preparations etc.Along with the raising of living standards of the people, also more and more higher to the requirement of the quality of animal food, therefore, many drawbacks such as the drug resistance problems that antibiotic, hormone and other chemical drugss exist, the residual problem of food medicine and problem of environmental pollution, seriously limit it to develop, particularly in food animal field.Herbal medicine has unique advantage in some functional diseases for the treatment of animal, and its side effect is relatively little, entering through absorbing and basic drug residue free after metabolism in animal body, promoting to have huge potentiality in the development that livestock and poultry breeding industry is healthy and orderly.
The preparation of Chinese powder medicine comprises pulverizes and mixes two basic working procedure.Different constituent presents different dry jet mixing pile after pulverizing, existing disintegrating process operation is coarse, preparation condition is simple and crude, equipment refinement degree is low, after causing the various compositions of Chinese powder medicine to pulverize, mixing is uneven, affect the stability of product quality, thus affect the problem such as effectiveness, safety of product.
Aurantii Immaturi and Atractylodis Pill is Chinese medicine side, has effect of spleen invigorating stomach strengthening, promoting digestion and removing stagnation, utilizes Fructus Aurantii Immaturus, the Rhizoma Atractylodis Macrocephalae coordinates other Chinese crude drugs to produce Chinese powder medicine as the Rhizoma Pinelliae gradually to be studied by industry technical staff.The preparation technology of its ordinary powder generally adopts and the one in constituent is condensed into extractum as the Rhizoma Pinelliae carries out extraction, and co-grinding is carried out in other constituents, then by extractum with pulverize after powder body mix, drying and screening Chinese powder medicine.The production technology of above-mentioned traditional preparation methods is simple, because the powder body after co-grinding has very high surface free energy, easily automatically reunite, due to the randomness that powder body is assembled, cause the randomness of powder property, the dispersed, controlled of powder body cannot be ensured, simultaneously, containing a large amount of volatile ingredients in Fructus Aurantii Immaturus, Rhizoma Atractylodis Macrocephalae, long-term placement is easily lost, thus makes finished product Chinese powder medicine there is the problems such as volatile ingredient easily scatters and disappears, color and luster is uneven, mouthfeel abnormal smells from the patient is poor.
Summary of the invention
In view of this, the invention provides a kind of Chinese medicine particle design promoting growth of animals or poultry loose and preparation method thereof, introduce modern particle design technology, utilize gravitation principle between granule, adopt the less Rhizoma Dioscoreae of particle diameter, Fructus Hordei Germinatus (parched) medical material micropowder, by Fructus Aurantii Immaturus larger for particle diameter and Rhizoma Atractylodis Macrocephalae micropowder parcel wherein, reach taste masking and prevent the object of effective ingredient volatilization loss, preparation stability is strengthened, thus ensures that stablizing of product quality is controlled.
For solving above technical problem, technical scheme of the present invention is, provide a kind of and promote that the Chinese medicine particle design of growth of animals or poultry is fallen apart, its constituent by weight, comprising:
On traditional Aurantii Immaturi and Atractylodis Pill formula basis, add Rhizoma Dioscoreae spleen reinforcing, supplementing QI and nourishing YIN, separately add a large amount of Fructus Hordei Germinatus (parched) promote qi circulation digestion promoting, spleen benefiting and stimulating the appetite, full side plays spleen invigorating stomach strengthening altogether, promotes effect of poultry dirty swine length.
The preparation method that the Chinese medicine particle design of above-mentioned promotion growth of animals or poultry is loose, comprises the steps;
(1) medical material pre-treatment: get the Rhizoma Atractylodis Macrocephalae, Fructus Aurantii Immaturus, Fructus Hordei Germinatus (parched), Rhizoma Dioscoreae four Chinese medicine material, carry out forced air drying or drying under reduced pressure, be dried to water content less than 3%, carry out routine respectively by conventional grinder and pulverize, cross No. 6 sieves, fine medicinal material powder is for subsequent use;
(2) produce Folium Nelumbinis extractum: get Folium Nelumbinis medical material, add 20 times of water boiling and extraction 2 times of Folium Nelumbinis weight, each 1 hour, filter, filtrate is concentrated to obtain Folium Nelumbinis extractum, for subsequent use;
(3) prepare the Rhizoma Atractylodis Macrocephalae, Fructus Aurantii Immaturus, Folium Nelumbinis mixing fine powders: get the Rhizoma Atractylodis Macrocephalae, Fructus Aurantii Immaturus two taste fine medicinal material powder, put mix homogeneously in mortar, add in the extractum of previous step gained, mixing drying after, after No. 6 sieve mixing fine powder, for subsequent use;
(4) prepare Chinese medicine particle design to fall apart: get Fructus Hordei Germinatus (parched), Rhizoma Dioscoreae two taste fine medicinal material powder, put mix homogeneously in mortar, drop in super micron mill and pulverize, pulverize after 10-30 minutes, again previous step gained mixing fine powders is continued to add in super micron mill, pulverize preparation 2-8 minutes, must promote that the Chinese medicine particle design of growth of animals or poultry is fallen apart.
Preferably, producing the Folium Nelumbinis extractum concentration produced in Folium Nelumbinis extractum step described in is that every 1ml contains 3g crude drug in whole.
Preferably, described conventional grinder is 500 type pulverizers, once can pulverize 500g medical material, and it is by the main axis of driven by motor, and motor speed is 3000r/min, and smashing fineness is 30-140 orders;
Preferably, described super micron mill is vibration grinding type super micron mill, and smashing fineness is more than 200 orders.
Preferably, the concrete operations of described micronizing medical material are: the concrete operations of described micronizing medical material are: get Fructus Hordei Germinatus (parched), Rhizoma Dioscoreae two taste fine medicinal material powder, put mix homogeneously in mortar, drop in super micron mill and pulverize, pulverize under minus 20 degrees constant temperature after 20 minutes, again the fine powder of mixing is added in super micron mill, pulverize preparation 3 minutes, must promote that the Chinese medicine particle design of growth of animals or poultry is fallen apart.
Compared with prior art, tool of the present invention has the following advantages:
The present invention adopts that preparation technology is simple, finished product good drug efficacy: the present invention utilizes the captivation between different-grain diameter powder body, the Rhizoma Dioscoreae that employing particle diameter is less, Fructus Hordei Germinatus (parched) medical material micropowder, Fructus Aurantii Immaturus larger for particle diameter and Rhizoma Atractylodis Macrocephalae powder body are wrapped up wherein, reach taste masking and prevent the object of effective ingredient volatilization loss, preparation stability is strengthened, thus ensureing that stablizing of product quality is controlled, drug effect is more remarkable; And the powder after the small particle diameter parcel Large stone that the present invention adopts mutually, do not need to add adjuvant seasoning, save the production cost of adjuvant, the taste of finished product is better.
Detailed description of the invention
In order to make those skilled in the art understand technical scheme of the present invention better, below in conjunction with specific embodiment, the present invention is described in further detail.
Below in conjunction with embodiment, the specific embodiment of the present invention is further described.Following examples only for technical scheme of the present invention is clearly described, and can not limit the scope of the invention with this.
Embodiment one
A kind of Chinese medicine particle design promoting growth of animals or poultry is fallen apart, and its constituent by weight, comprising:
Add Rhizoma Dioscoreae spleen reinforcing, supplementing QI and nourishing YIN, add a large amount of Fructus Hordei Germinatus (parched) promote qi circulation digestion promoting, spleen benefiting and stimulating the appetite, full side plays spleen invigorating stomach strengthening altogether, promotes effect of growth of animals or poultry.
Promote that the preparation technology that the Chinese medicine particle design of growth of animals or poultry is loose is as follows:
Get the Rhizoma Atractylodis Macrocephalae, Fructus Aurantii Immaturus, Fructus Hordei Germinatus (parched), Rhizoma Dioscoreae four Chinese medicine material, carry out forced air drying or drying under reduced pressure, be dried to water content less than 3%, carry out routine respectively by conventional grinder and pulverize, cross No. 6 sieves, fine medicinal material powder is for subsequent use; Get Folium Nelumbinis medical material, add 20 times amount water boiling and extraction 2 times, each 1 hour, filter, filtrate is concentrated into the extractum of every 1ml containing 2g raw medicinal herbs, for subsequent use; Get the Rhizoma Atractylodis Macrocephalae, Fructus Aurantii Immaturus two taste fine medicinal material powder, put mix homogeneously in mortar, add in the extractum of previous step gained, mixing drying after, after No. 6 sieve mixing fine powder, for subsequent use; Get Fructus Hordei Germinatus (parched), Rhizoma Dioscoreae two taste fine medicinal material powder, put mix homogeneously in mortar, drop in super micron mill and pulverize, pulverize under minus 20 degrees constant temperature after 20 minutes, again previous step gained mixing fine powders is continued to add in super micron mill, pulverize preparation 3 minutes, must promote that the Chinese medicine particle design of growth of animals or poultry is fallen apart.Conventional pulverizing adopts conventional grinder to carry out, and described conventional grinder is 500 type pulverizers, once can pulverize 500g medical material, and it is by the main axis of driven by motor, and motor speed is 3000r/min, and smashing fineness is 30-140 orders.Described super micron mill is vibration grinding type super micron mill, and smashing fineness is more than 200 orders.
Embodiment two
A kind of ordinary powder, its constituent by weight, comprising:
The preparation technology of ordinary powder is as follows:
Get Folium Nelumbinis medical material, add 20 times amount water boiling and extraction 2 times, each 1 hour, filter, filtrate is concentrated into the extractum of every 1ml containing 2g raw medicinal herbs, for subsequent use; Get residue prescription 4 taste medical material, after conventional pulverizing, cross No. 6 sieves, extractum is added in fine powder and mixes, dry, cross No. 6 sieves, to obtain final product.
Fall apart with regard to the Chinese medicine particle design of the promotion growth of animals or poultry of embodiment one and embodiment two below and the experiment Analysis such as various parameters, drug effect of ordinary powder:
1, contrast the face shaping of two kinds of powders, comprise color, gas, taste, shown in result table 1.
Table 1 outward appearance comparing result
From comparing result, the loose comparatively ordinary powder of particle design is even, and volatile ingredient abnormal smells from the patient is not obvious, and to the parcel of volatile ingredient, comparatively ordinary powder is good.
2, stability comparing result
Take two kinds of powders respectively, put in weighing botle, in 40 DEG C, place under the condition of 75% humidity, respectively at sampling and measuring active constituent content in 0,5,10 day, each sample parallel measures 3 times, and measurement result is in table 2.
Table 2 stability experiment contrasts
From comparing result, in ordinary powder, two kinds of main volatile compounds are lost comparatively large under hot and humid environment, and the loose middle volatile ingredient loss of particle design is relatively little, therefore, particle design is loose, and comparatively ordinary powder is more reasonable, is conducive to the long-term preservation of preparation.
3, clinical effectiveness demonstration test
3.1 test grouping and process
Choose the 1 age in days broiler chicks 150 that health, body weight are basically identical, be divided into 3 groups at random, often organize 50.1 group is blank group (not administration), 2 groups be ordinary powder administration group (by every day forage volume 5% amount spice to the ordinary powder with embodiment two), 3 groups be particle design fall apart administration group (by every day forage volume 5% amount spice to the particle design powder with implementation column one).Experimental period, is: 5 ~ 42 ages in days, to enter the young same day as 1 age in days.
3.2 basal diet composition and trophic levels
According to the fast large-scale feeding of broiler standard preparation of China, daily ration is once got all the ready.
3.3 feedings and managements and immunity
Test chicken all adopts bilayer to raise in cages, and free choice feeding and drinking-water, experimental period is 5 ~ 42 ages in days, and hen house keeps hygienically clean, well-ventilated.
3.4 test indexs and method
Respectively at before test, 42 age in days time by only weighing on an empty stomach, weigh broiler fodder consumption every day, statistical respectively organizes average weight, daily gain, feed consumption rate, feedstuff-meat ratio etc.
3.5 result of the tests and analysis
Table 3 result of the test compares
As shown in Table 3, ordinary powder group and particle design group of faling apart all has obvious digestion promoting effect, can promote broiler fodder consumption, broiler daily body weight gain is also apparently higher than blank group, but particle design is fallen apart, group is obviously better than ordinary powder group, from feedstuff-meat ratio, particle design falls apart group lower than common loose group, common loose group lower than blank group, this also demonstrates the effect of this preparation invigorating the stomach and promoting digestion, facilitating digestion, can the price of deed be improved, reduce feeding cost etc.Particle design is fallen apart the formulation design approach owing to have employed innovation, itself introduces superfine communication technique, preparation is better absorbed in animal body, curative effect gets a promotion, there is preparation stability simultaneously high, the advantages such as effective ingredient not easily loses, gained promotes that the Chinese medicine particle design of growth of animals or poultry is loose can be widely used in beasts field.
Embodiment three
A kind of preparation technology promoting that the Chinese medicine particle design of growth of animals or poultry is loose is as follows:
Get the Rhizoma Atractylodis Macrocephalae, Fructus Aurantii Immaturus, Fructus Hordei Germinatus (parched), Rhizoma Dioscoreae four Chinese medicine material, carry out forced air drying or drying under reduced pressure, be dried to water content less than 3%, carry out routine respectively by conventional grinder and pulverize, cross No. 6 sieves, fine medicinal material powder is for subsequent use; Get Folium Nelumbinis medical material, add 20 times amount water boiling and extraction 2 times, each 1 hour, filter, filtrate is concentrated into the extractum of every 1ml containing 2g raw medicinal herbs, for subsequent use; Get the Rhizoma Atractylodis Macrocephalae, Fructus Aurantii Immaturus two taste fine medicinal material powder, put mix homogeneously in mortar, add in the extractum of previous step gained, mixing drying after, after No. 6 sieve mixing fine powder, for subsequent use; Get Fructus Hordei Germinatus (parched), Rhizoma Dioscoreae two taste fine medicinal material powder, put mix homogeneously in mortar, drop in super micron mill and pulverize, pulverize under 18 degrees below zero constant temperature after 10 minutes, again previous step gained mixing fine powders is continued to add in super micron mill, pulverize preparation 2 minutes, must promote that the Chinese medicine particle design of growth of animals or poultry is fallen apart.Conventional pulverizing adopts conventional grinder to carry out, and described conventional grinder is 500 type pulverizers, once can pulverize 500g medical material, and it is by the main axis of driven by motor, and motor speed is 3000r/min, and smashing fineness is 30-140 orders.Described super micron mill is vibration grinding type super micron mill, and smashing fineness is more than 200 orders.
Because in the Rhizoma Atractylodis Macrocephalae, Fructus Aurantii Immaturus, volatile oil component is more, easy volatilization loss, adopts the Fructus Hordei Germinatus (parched) that particle diameter is little, the Rhizoma Atractylodis Macrocephalae, Fructus Aurantii Immaturus that Rhizoma Dioscoreae parcel particle diameter is larger, volatility is wrapped up, be convenient to preserve, make the Chinese medicine particle design of the present embodiment drug effect of faling apart better than ordinary powder.
Below be only the preferred embodiment of the present invention, it should be pointed out that above-mentioned preferred implementation should not be considered as limitation of the present invention, protection scope of the present invention should be as the criterion with claim limited range.For those skilled in the art, without departing from the spirit and scope of the present invention, some improvements and modifications can also be made and also should be considered as protection scope of the present invention.
Claims (5)
1. promote the preparation method that the Chinese medicine particle design of growth of animals or poultry is loose, it is characterized in that, described preparation method comprises the following steps:
(1) medical material pre-treatment: get count by weight the Rhizoma Atractylodis Macrocephalae 26.5 parts, Fructus Aurantii Immaturus 13.5 parts, Fructus Hordei Germinatus (parched) 27.0 parts, Rhizoma Dioscoreae 26.5 parts, carry out forced air drying or drying under reduced pressure, be dried to water content less than 3%, carry out routine respectively by conventional grinder to pulverize, cross No. 6 sieves, fine medicinal material powder is for subsequent use;
(2) produce Folium Nelumbinis extractum: get 6.5 parts, the Folium Nelumbinis counted by weight, add 20 times of water boiling and extraction 2 times of Folium Nelumbinis weight, each 1 hour, filter, filtrate is concentrated to obtain Folium Nelumbinis extractum, for subsequent use;
(3) prepare the Rhizoma Atractylodis Macrocephalae, Fructus Aurantii Immaturus, Folium Nelumbinis mixing fine powders: get the Rhizoma Atractylodis Macrocephalae, Fructus Aurantii Immaturus two taste fine medicinal material powder, put mix homogeneously in mortar, add in the extractum of previous step gained, mixing drying after, after No. 6 sieve mixing fine powder, for subsequent use;
(4) prepare Chinese medicine particle design to fall apart: get Fructus Hordei Germinatus (parched), Rhizoma Dioscoreae two taste fine medicinal material powder, put mix homogeneously in mortar, drop in super micron mill and pulverize, pulverize after 10-30 minutes, again previous step gained mixing fine powders is continued to add in super micron mill, pulverize preparation 2-8 minutes, must promote that the Chinese medicine particle design of growth of animals or poultry is fallen apart.
2. promote as claimed in claim 1 to it is characterized in that the preparation method that the Chinese medicine particle design of growth of animals or poultry is loose, described in produce the Folium Nelumbinis extractum concentration produced in Folium Nelumbinis extractum step be that every 1ml contains 3g crude drug in whole.
3. promote the preparation method that the Chinese medicine particle design of growth of animals or poultry is loose as claimed in claim 1, it is characterized in that, described conventional grinder is 500 type pulverizers, once can pulverize 500g medical material, it is by the main axis of driven by motor, motor speed is 3000r/min, and smashing fineness is 30-140 orders.
4. promote the preparation method that the Chinese medicine particle design of growth of animals or poultry is loose as claimed in claim 1, it is characterized in that, described super micron mill is vibration grinding type super micron mill, and smashing fineness is more than 200 orders.
5. promote the preparation method that the Chinese medicine particle design of growth of animals or poultry is loose as claimed in claim 1, it is characterized in that, the concrete operations of described micronizing medical material are: get Fructus Hordei Germinatus (parched), Rhizoma Dioscoreae two taste fine medicinal material powder, put mix homogeneously in mortar, drop in super micron mill and pulverize, pulverize after 20 minutes under minus 20 degrees constant temperature, then the fine powder of the mixing of previous step gained is added in super micron mill, pulverize preparation 3 minutes, must promote that the Chinese medicine particle design of growth of animals or poultry is fallen apart.
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| CN104398650A (en) * | 2014-11-12 | 2015-03-11 | 成都乾坤动物药业有限公司 | Preparation method of pharmaceutical composition for treating swine febrile disease |
| CN108201096A (en) * | 2017-12-29 | 2018-06-26 | 李今芳 | A kind of healthcare function edible powder and preparation method thereof |
| CN109381654B (en) * | 2018-06-01 | 2021-08-20 | 陕西中医药大学 | Preparation of ginseng, poria cocos and bighead atractylodes rhizome powder |
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| CN101693092A (en) * | 2009-09-28 | 2010-04-14 | 许永喜 | Traditional Chinese medicine powder for treating child anorexia |
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| CN101693092A (en) * | 2009-09-28 | 2010-04-14 | 许永喜 | Traditional Chinese medicine powder for treating child anorexia |
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| 中药超微粉概述及其防控猪病的研究进展;杨海涵等;《兽医导刊》;20111231(第5期);第47-49页 * |
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Address after: 611130 Wenjiang, Chengdu, Chengdu cross strait science and Technology Industrial Development Zone, Jin Fu Road, Sichuan Patentee after: Chengdu Qiankun animal pharmaceutical Limited by Share Ltd Address before: 611130 Wenjiang, Chengdu, Chengdu cross strait science and Technology Industrial Development Zone, Jin Fu Road, Sichuan Patentee before: Chengdu Qiankun Animal Pharmaceutical Co.,Ltd. |