CN103330884B - Ointment for treating dermatitis - Google Patents

Ointment for treating dermatitis Download PDF

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CN103330884B
CN103330884B CN201310227030.1A CN201310227030A CN103330884B CN 103330884 B CN103330884 B CN 103330884B CN 201310227030 A CN201310227030 A CN 201310227030A CN 103330884 B CN103330884 B CN 103330884B
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parts
radix
stearic acid
dermatitis
ointment
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CN103330884A (en
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汪胜松
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Anhui Province Qimen County Research Institute Of Snake Wound
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Anhui Province Qimen County Research Institute Of Snake Wound
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Abstract

The invention relates to an ointment for treating dermatitis. The ointment is prepared by the following steps: preparing golden cypress, Agastache rugosus, pollen typhae, radix stemonae, Chinese lobelia, edible tulip, rhizoma atractylodis, rumex japonicus root, Jacaranda flower, radix angelicae and radix sophorae flavescentis; adding water which is 5-7 times mass of the medicinal materials, detecting for 2-3 hours; removing dregs; concentrating the medicine liquid to prepare a thick paste for later use; preparing snake oil and stearic acid; heating to 80-90 DEG C and maintaining the temperate so that snake oil and stearic acid are melted; additionally taking boiling water which is equal to stearic acid in mass, as well as triethanolamine, glycerol and sodium benzoate, heating to 80-90 DEG C and maintaining the temperate; gradually adding into the melted snake oil and stearic acid; continuously stirring; after uniformly stirring, cooling to emulsus; after temperature is reduced to below 30 DEG C, grinding borneol and alums to fine paste; and adding the thick paste for later use and uniformly stirring. The ointment provided by the invention effectively treats dermatitis, eczema and the like, and is convenient to use, and meanwhile, lesion and drug dependence possibly caused by Western medicines can be avoided.

Description

A kind of dermatitis in treatment ointment
Technical field
The present invention relates to the dermopathic externally-applied ointment for the treatment of, particularly relate to a kind of dermatitis in treatment ointment.
Background technology
Dermatitis is clinical comparatively common disease, and according to the dermatitis mode classification that world's allergia Organisation recommendations uses, dermatitis is divided into eczema, contact dermatitis, other types dermatitis.At present for dermatitis in treatment medicine, mostly what doctor trained in Western medicine mainly adopted is corticosteroids medicine, antihistamine for oral administration and antibiotics.But in recent years, the skin lesion caused due to external hormone preparation sharply increases, untoward reaction is remarkable, becomes the social problem that people show great attention to.Long-term external hormone can cause osteoporosis, hypoimmunity, fungal infection, atrophoderma, pigmentation, telangiectasis, burn feeling, striae atrophicae, hirsutism, acne and rosacea sample erythra.
Hormone has obvious non-specific inhibitory action to the scytitis that a variety of causes (as infection, allergy, physical agent etc.) causes, though the state of an illness can be made after external to improve rapidly, but it is short-term relief symptom, inflammation-inhibiting reacts, instead of healing inflammation, fundamentally can not treat the cause of disease.The abuse of hormone, also can cause steroid-dependent dermatitis to occur, once drug withdrawal will recur or worsen.When after external hormone again, above-mentioned symptom or sign disappear very soon, once again drug withdrawal, send out rapidly again, and more more violent than previous, and general medicine is difficult to control.The application of western medicine antibiotics is the essential therapeutic arsenals of department of dermatologry, but the phenomenon abused in the process of application grows in intensity, and this not only causes the serious waste of medicine, also increases the generation of bacterial drug resistance, causes huge harm to society.
What Chinese traditional treatment dermatitis mainly adopted is oral decoction, the combined therapy of external-use lotion, although the pathological changes that the non-rational use of drug avoiding various doctor trained in Western medicine causes, drug dependence etc., but oral decoction mouthfeel is pained, there is difficulty especially for taking of children's, treatment is inconvenient.Thus, the pathological changes that may cause in simultaneously avoiding Western medicine to use and drug dependence, can avoid again the medicine of Chinese herbal oral decoction mouthfeel bitterness urgently to develop.
Summary of the invention
The object of the invention is to solve in treatment dermatitis, the pathological changes that Western medicine may cause in using and drug dependence, the problem of Chinese herbal oral decoction mouthfeel bitterness.Inventor is according to oneself clinical accumulation for many years, and have developed a kind of dermatitis in treatment ointment, this unguentum effectively can treat dermatitis, easy to use, avoids during Western medicine uses the pathological changes and drug dependence that may cause simultaneously.
The technical scheme that the present invention solves its technical problem is:
A kind of preparation method of dermatitis in treatment ointment, by weight, get Cortex Phellodendri 50 ~ 70 parts, Herba Pogostemonis 50-70 part, Pollen Typhae 40-90 part, the Radix Stemonae 50 ~ 70 parts, Herba Lobeliae Chinensis 80 ~ 120 parts, Pseudobulbus Cremastrae Seu Pleiones 80 ~ 120 parts, Rhizoma Atractylodis 70 ~ 90 parts, Radix Rumicis Crispi 80 ~ 120 parts, Radix campsis spend 180 ~ 220 parts, the Radix Angelicae Dahuricae 50 ~ 70 parts, Radix Sophorae Flavescentis 50 ~ 70 parts, Adeps Serpentis 50 ~ 70 parts, stearic acid 50 ~ 70 parts, triethanolamine 35 ~ 45 parts, glycerol 25 ~ 30 parts, sodium benzoate 3 ~ 5 parts, Borneolum Syntheticum 8 ~ 12 parts, 8 ~ 12 parts, Alumen;
Get above-mentioned Cortex Phellodendri, Herba Pogostemonis, Pollen Typhae, the Radix Stemonae, Herba Lobeliae Chinensis, Pseudobulbus Cremastrae Seu Pleiones, Rhizoma Atractylodis, Radix Rumicis Crispi, Radix campsis flower, the Radix Angelicae Dahuricae, Radix Sophorae Flavescentis, add 5 ~ 7 times to the soak by water 2 ~ 3 hours of quality of medicinal material, discard medicinal residues, concentration of liquid medicine is obtained thick paste, for subsequent use;
Get above-mentioned Adeps Serpentis and stearic acid, heating maintenance 80 ~ 90 DEG C, makes it fusing, separately gets and the boiling water of the homogenous quantities such as described stearic acid and above-mentioned triethanolamine, glycerol, sodium benzoate, heating maintenance 80 ~ 90 DEG C, in the stearic acid adding fusing gradually and Adeps Serpentis, constantly stir, let cool to emulsus after evenly, treat that temperature is reduced to less than 30 DEG C, get above-mentioned Borneolum Syntheticum, Alumen and grind to form fine and smooth pasty state together, add thick paste for subsequent use, stir.
Preferably, described Cortex Phellodendri 60 parts, Herba Pogostemonis 60 parts, Pollen Typhae 60, the Radix Stemonae 60 parts, Herba Lobeliae Chinensis 100 parts, Pseudobulbus Cremastrae Seu Pleiones 100 parts, Rhizoma Atractylodis 80 parts, Radix Rumicis Crispi 100 parts, Radix campsis spend 200 parts, the Radix Angelicae Dahuricae 60 parts, Radix Sophorae Flavescentis 60 parts, Borneolum Syntheticum 10 parts, 10 parts, Alumen, Adeps Serpentis 60 parts, stearic acid 60 parts, triethanolamine 40 parts, glycerol 30 parts, sodium benzoate 3 parts.
In order to obtain the thick paste of better drug effect, described gets above-mentioned Cortex Phellodendri, Herba Pogostemonis, Pollen Typhae, the Radix Stemonae, Herba Lobeliae Chinensis, Pseudobulbus Cremastrae Seu Pleiones, Rhizoma Atractylodis, Radix Rumicis Crispi, Radix campsis flower, the Radix Angelicae Dahuricae, Radix Sophorae Flavescentis, be placed in boiling machine, add the water of 5 ~ 7 times of quality of medicinal material ratios in boiling machine, repeatedly decoct 2 times, each decoction 1 hour, discard medicinal residues, merge the medicinal liquid of twice decoction, concentration of liquid medicine is obtained thick paste, for subsequent use.
Described heating is heating in water bath.
In order to improve the abnormal smells from the patient of ointment, also the osmanthus flower fragrance of desirable weight portion 10 ~ 15 parts grinds to form fine and smooth pasty state together with above-mentioned Borneolum Syntheticum, Alumen, adds thick paste for subsequent use, stirs.
Usage and dosage: external preparation for skin, follows the doctor's advice.Take a morsel and be applied to affected part, and gently rub a moment.
Points for attention: 1, agents area should drug withdrawal if any the situation such as burn feeling, redness, and local is cleaned, or for a long time, large area seeks advice to doctor when using.2, forbid when character of the present invention changes.
Adeps Serpentis contains unsaturated fatty acid, linolenic acid, linoleic acid, has good permeability.Have endocrine regulation imbalance, loosening bowel to relieve constipation, skin maintenance, prevents skin aging, prevents effect of sclerosis of blood vessels, detumescence, bacteria growing inhibiting, blood circulation promoting.In addition Radix Rumicis Crispi, Herba Lobeliae Chinensis, Radix campsis flower, Pseudobulbus Cremastrae Seu Pleiones then have the effect of heat-clearing and toxic substances removing.Cortex Phellodendri, Radix Sophorae Flavescentis, Rhizoma Atractylodis, the Radix Stemonae are got its heat clearing away, dry, the merit of parasite killing.The Radix Angelicae Dahuricae then has antiinflammatory action, and main containing volatile ingredient and Coumarins, the mouse stomach Radix Angelicae Dahuricae or Radix Angelicae Dahuricae decoct (the suitable crude drug lg of lg) 4g/kg, obviously can suppress the inflammation (P<0.01) of dimethylbenzene induced mice ear.Obvious antiplatelet aggregation is had, is the effective ingredient of blood circulation promoting and blood stasis dispelling that there is antiinflammatory, antianaphylactic effect simultaneously containing total flavones in Pollen Typhae.
The invention has the beneficial effects as follows, can effectively treat dermatitis, eczema, easy to use, avoid the life-time service such as hormone, antibiotic, the pathological changes that may cause, side reaction and drug dependence simultaneously.
Detailed description of the invention
The preparation of embodiment 1, a kind of dermatitis in treatment ointment
Get Cortex Phellodendri 50g, Herba Pogostemonis 60 parts, Pollen Typhae 60, Radix Stemonae 50g, Herba Lobeliae Chinensis 80g, Pseudobulbus Cremastrae Seu Pleiones 80g, Rhizoma Atractylodis 70g, Radix Rumicis Crispi 80g, Radix campsis flower 180g, Radix Angelicae Dahuricae 50g, Radix Sophorae Flavescentis 50g, Adeps Serpentis 50g, stearic acid 50g, triethanolamine 35g, glycerol 25g, sodium benzoate 3g, Borneolum Syntheticum 8g, Alumen 8g, osmanthus flower fragrance 10g are stand-by.
Get above-mentioned Cortex Phellodendri, Herba Pogostemonis, Pollen Typhae, the Radix Stemonae, Herba Lobeliae Chinensis, Pseudobulbus Cremastrae Seu Pleiones, Rhizoma Atractylodis, Radix Rumicis Crispi, Radix campsis flower, the Radix Angelicae Dahuricae, Radix Sophorae Flavescentis, add the soak by water 2 of 5 times of quality of medicinal material ratios in boiling machine little time, discard medicinal residues, concentration of liquid medicine obtained thick paste, for subsequent use;
Get above-mentioned Adeps Serpentis and stearic acid, heating maintenance 80 ~ 90 DEG C, makes it fusing, separately get and the boiling water of the homogenous quantities such as described stearic acid and above-mentioned triethanolamine, glycerol, sodium benzoate, heating maintenance 80 ~ 90 DEG C, in the stearic acid adding fusing gradually and Adeps Serpentis, constantly stirs, let cool to emulsus after evenly, treat that temperature is reduced to less than 30 DEG C, get above-mentioned Borneolum Syntheticum, Alumen, osmanthus flower fragrance and grind to form fine and smooth pasty state together, add thick paste for subsequent use, stir, obtain dermatitis in treatment ointment.
The preparation of embodiment 2, a kind of dermatitis in treatment ointment and use
Get Cortex Phellodendri 60g, Herba Pogostemonis 60 parts, Pollen Typhae 60, Radix Stemonae 60g, Herba Lobeliae Chinensis 100g, Pseudobulbus Cremastrae Seu Pleiones 100g, Rhizoma Atractylodis 80g part, Radix Rumicis Crispi 100g, Radix campsis flower 200g, Radix Angelicae Dahuricae 60g, Radix Sophorae Flavescentis 60g, Adeps Serpentis 60g, stearic acid 60g, triethanolamine 40g, glycerol 25g, sodium benzoate 4g, Borneolum Syntheticum 8g, Alumen 8g; Osmanthus flower fragrance 12g is stand-by.
In order to obtain better thick paste, described gets above-mentioned Cortex Phellodendri, Herba Pogostemonis, Pollen Typhae, the Radix Stemonae, Herba Lobeliae Chinensis, Pseudobulbus Cremastrae Seu Pleiones, Rhizoma Atractylodis, Radix Rumicis Crispi, Radix campsis flower, the Radix Angelicae Dahuricae, Radix Sophorae Flavescentis, be placed in boiling machine, add the water of 7 times of quality of medicinal material ratios in boiling machine, repeatedly decoct 2 times, each decoction 1 hour, discard medicinal residues, merge the medicinal liquid of twice decoction, concentration of liquid medicine is obtained thick paste, for subsequent use.
Described heating is heating in water bath.
Get above-mentioned Adeps Serpentis and stearic acid, heating in water bath keeps 80 ~ 90 DEG C, make it fusing, separately get and the boiling water of the homogenous quantities such as described stearic acid and above-mentioned triethanolamine, glycerol, sodium benzoate, heating in water bath keeps 80 ~ 90 DEG C, in the stearic acid adding fusing gradually and Adeps Serpentis, continuous stirring, let cool to emulsus after evenly, treat that temperature is reduced to less than 30 DEG C, get above-mentioned Borneolum Syntheticum, Alumen, osmanthus flower fragrance and grind to form fine and smooth pasty state together, add thick paste for subsequent use, stir, obtain dermatitis in treatment ointment.
The preparation of embodiment 3, a kind of dermatitis in treatment ointment and use
Get Cortex Phellodendri 70g, Herba Pogostemonis 60 parts, Pollen Typhae 60, Radix Stemonae 70g, Herba Lobeliae Chinensis 120g, Pseudobulbus Cremastrae Seu Pleiones 120g, Rhizoma Atractylodis 90g, Radix Rumicis Crispi 120g, Radix campsis flower 220g, Radix Angelicae Dahuricae 70g, Radix Sophorae Flavescentis 70g, Adeps Serpentis 70g, stearic acid 70g, triethanolamine 45g, glycerol 30g, sodium benzoate 5g, Borneolum Syntheticum 12g, Alumen 12g; Osmanthus flower fragrance 15g is stand-by.
In order to obtain better thick paste, described gets above-mentioned Cortex Phellodendri, Herba Pogostemonis, Pollen Typhae, the Radix Stemonae, Herba Lobeliae Chinensis, Pseudobulbus Cremastrae Seu Pleiones, Rhizoma Atractylodis, Radix Rumicis Crispi, Radix campsis flower, the Radix Angelicae Dahuricae, Radix Sophorae Flavescentis, be placed in boiling machine, add the water of 6 times of quality of medicinal material ratios in boiling machine, repeatedly decoct 2 times, each decoction 1 hour, discard medicinal residues, merge the medicinal liquid of twice decoction, concentration of liquid medicine is obtained thick paste, for subsequent use.
Described heating is heating in water bath.
Get above-mentioned Adeps Serpentis and stearic acid, heating in water bath keeps 80 ~ 90 DEG C, make it fusing, separately get and the boiling water of the homogenous quantities such as described stearic acid and above-mentioned triethanolamine, glycerol, sodium benzoate, heating in water bath keeps 80 ~ 90 DEG C, in the stearic acid adding fusing gradually and Adeps Serpentis, continuous stirring, let cool to emulsus after evenly, treat that temperature is reduced to less than 30 DEG C, get above-mentioned Borneolum Syntheticum, Alumen, osmanthus flower fragrance and grind to form fine and smooth pasty state together, add thick paste for subsequent use, stir, obtain dermatitis in treatment ointment.
Clinical example 1
Open ××, female, 43 years old, village's name.Patient on July 11st, 2009 come I go to a doctor.
Symptom: cervical region, arm, skin of dorsum of hand have erythema; Cutaneous lesion has burn feeling, gargalesthesia or twinge.There are fever, weak, general malaise.
Be diagnosed as solar dermatitis.
Get ointment of the present invention and be applied to affected part, and gently rub a moment, smeared once every four hours, next day fully recovers.
Clinical example 2
Open ××, female, 21 years old, student.Patient in JIUYUE in 2010 within 12nd, come I go to a doctor.
Symptom: scalp, face slightly flushing patch, above covers canescence bran shape squama, accompanies slight pruritus, and the serious place of face infringement is the wing of nose, nasolabial fold and geisoma, has light red mottle, coated with the yellow squama of greasy.
Be diagnosed as seborrheic dermatitis.
Get ointment of the present invention and be applied to affected part, and gently rub a moment, smeared once every four hours, fully recover after two days.
Clinical example 3
King's ××, man, 33 years old, driver.Patient in December in 2010 within 12nd, come I go to a doctor.
Symptom: groin, crissum anal cleft portion, axillary fossa is local skin flushing, mild swelling, and it is rotten to the corn that surface is slight, and secretions has foreign odor taste.Sometimes also can in dry, desquamation.
Be diagnosed as and read coccus dermatitis.
Get ointment of the present invention and be applied to affected part, and gently rub a moment, smeared once every four hours, resolution of symptoms after two days, continue to cure for two weeks.
Clinical example 4
King's ××, man, 10 years old, student.Patient on July 12nd, 2011 come I go to a doctor.
Symptom: face, back, front miliaria are gathered.
Be diagnosed as insect bite dermatitis.
Get ointment of the present invention and be applied to affected part, and gently rub a moment, smeared once every four hours, resolution of symptoms after two days, continue to cure for 5 days.

Claims (5)

1. a dermatitis in treatment ointment, obtained by following methods step: by weight, first get Cortex Phellodendri 50 ~ 70 parts, Herba Pogostemonis 50-70 part, Pollen Typhae 40-90 part, the Radix Stemonae 50 ~ 70 parts, Herba Lobeliae Chinensis 80 ~ 120 parts, Pseudobulbus Cremastrae Seu Pleiones 80 ~ 120 parts, Rhizoma Atractylodis 70 ~ 90 parts, Radix Rumicis Crispi 80 ~ 120 parts, Radix campsis spend 180 ~ 220 parts, the Radix Angelicae Dahuricae 50 ~ 70 parts, Radix Sophorae Flavescentis 50 ~ 70 parts, Adeps Serpentis 50 ~ 70 parts, stearic acid 50 ~ 70 parts, triethanolamine 35 ~ 45 parts, glycerol 25 ~ 30 parts, sodium benzoate 3 ~ 5 parts, Borneolum Syntheticum 8 ~ 12 parts, 8 ~ 12 parts, Alumen;
Get above-mentioned Cortex Phellodendri, Herba Pogostemonis, Pollen Typhae, the Radix Stemonae, Herba Lobeliae Chinensis, Pseudobulbus Cremastrae Seu Pleiones, Rhizoma Atractylodis, Radix Rumicis Crispi, Radix campsis flower, the Radix Angelicae Dahuricae, Radix Sophorae Flavescentis, add 5 ~ 7 times to the soak by water 2 ~ 3 hours of quality of medicinal material, discard medicinal residues, concentration of liquid medicine is obtained thick paste, for subsequent use;
Get above-mentioned Adeps Serpentis and stearic acid, heating maintenance 80 ~ 90 DEG C, makes it fusing, separately gets and the boiling water of the homogenous quantities such as described stearic acid and above-mentioned triethanolamine, glycerol, sodium benzoate, heating maintenance 80 ~ 90 DEG C, in the stearic acid adding fusing gradually and Adeps Serpentis, constantly stir, let cool to emulsus after evenly, treat that temperature is reduced to less than 30 DEG C, get above-mentioned Borneolum Syntheticum, Alumen and grind to form fine and smooth pasty state together, add thick paste for subsequent use, stir.
2. dermatitis in treatment ointment as claimed in claim 1, is characterized in that: described Cortex Phellodendri 60 parts, Herba Pogostemonis 60 parts, Pollen Typhae 60 parts, the Radix Stemonae 60 parts, Herba Lobeliae Chinensis 100 parts, Pseudobulbus Cremastrae Seu Pleiones 100 parts, Rhizoma Atractylodis 80 parts, Radix Rumicis Crispi 100 parts, Radix campsis spend 200 parts, the Radix Angelicae Dahuricae 60 parts, Radix Sophorae Flavescentis 60 parts, Borneolum Syntheticum 10 parts, 10 parts, Alumen, Adeps Serpentis 60 parts, stearic acid 60 parts, triethanolamine 40 parts, glycerol 30 parts, sodium benzoate 3 parts.
3. dermatitis in treatment ointment as claimed in claim 1, it is characterized in that: described gets above-mentioned Cortex Phellodendri, Herba Pogostemonis, Pollen Typhae, the Radix Stemonae, Herba Lobeliae Chinensis, Pseudobulbus Cremastrae Seu Pleiones, Rhizoma Atractylodis, Radix Rumicis Crispi, Radix campsis flower, the Radix Angelicae Dahuricae, Radix Sophorae Flavescentis, be placed in boiling machine, add the water of 5 ~ 7 times of quality of medicinal material ratios in boiling machine, repeatedly decoct 2 times, each decoction 1 hour, discard medicinal residues, merge the medicinal liquid of twice decoction, concentration of liquid medicine is obtained thick paste, for subsequent use.
4. dermatitis in treatment ointment as claimed in claim 1, is characterized in that: described heating is heating in water bath.
5. the dermatitis in treatment ointment as described in Claims 1 to 4 any one, is characterized in that: the osmanthus flower fragrance getting weight portion 10 ~ 15 parts grinds to form fine and smooth pasty state together with above-mentioned Borneolum Syntheticum, Alumen, adds thick paste for subsequent use, stirs.
CN201310227030.1A 2013-06-08 2013-06-08 Ointment for treating dermatitis Active CN103330884B (en)

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CN103705750B (en) * 2014-01-13 2018-12-11 张淑芬 A kind of nursing of perianal eczema dresses scattered and preparation method thereof
CN105250567A (en) * 2015-11-10 2016-01-20 张霞 Traditional Chinese medicine ointment for treating eczematous dermatitis and preparation method thereof

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CN101357201A (en) * 2008-09-16 2009-02-04 杨运金 Multipurpose traditional Chinese medicine and preparation method thereof
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