CN103327972A - 取代的苯甲酰胺及其用途 - Google Patents
取代的苯甲酰胺及其用途 Download PDFInfo
- Publication number
- CN103327972A CN103327972A CN2011800595100A CN201180059510A CN103327972A CN 103327972 A CN103327972 A CN 103327972A CN 2011800595100 A CN2011800595100 A CN 2011800595100A CN 201180059510 A CN201180059510 A CN 201180059510A CN 103327972 A CN103327972 A CN 103327972A
- Authority
- CN
- China
- Prior art keywords
- compound
- methyl
- optionally substituted
- pyridyl
- sulfonyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 CC*1(C2)*2CCC1 Chemical compound CC*1(C2)*2CCC1 0.000 description 17
- HDOUGSFASVGDCS-UHFFFAOYSA-N NCc1cnccc1 Chemical compound NCc1cnccc1 HDOUGSFASVGDCS-UHFFFAOYSA-N 0.000 description 3
- YLRBJYMANQKEAW-UHFFFAOYSA-N BrCc(cc1)ccc1Br Chemical compound BrCc(cc1)ccc1Br YLRBJYMANQKEAW-UHFFFAOYSA-N 0.000 description 1
- NCUTUFSXCVKNAD-UHFFFAOYSA-N Brc1ccc(CCN2CCOCC2)cc1 Chemical compound Brc1ccc(CCN2CCOCC2)cc1 NCUTUFSXCVKNAD-UHFFFAOYSA-N 0.000 description 1
- XJIWMJSJHURIFS-SURVPKMZSA-N C/C=S(\Cc1c(C)[o]c(-c(cc2)ccc2C(NCc2cccnc2)=O)n1)/[C@@H](CC1)C[C@H]1N Chemical compound C/C=S(\Cc1c(C)[o]c(-c(cc2)ccc2C(NCc2cccnc2)=O)n1)/[C@@H](CC1)C[C@H]1N XJIWMJSJHURIFS-SURVPKMZSA-N 0.000 description 1
- JKCMHTNELDNMNY-UHFFFAOYSA-N CC(C)(C)OC(N1OC2C=CC1C2)=O Chemical compound CC(C)(C)OC(N1OC2C=CC1C2)=O JKCMHTNELDNMNY-UHFFFAOYSA-N 0.000 description 1
- WXEQJZLNVKZFOQ-ANPXMQTQSA-N CC(C)(C)OC(N[C@@H](CC1)C[C@@H]1C(CC(C/C(/NC)=C(\C)/OC)=O)=O)=O Chemical compound CC(C)(C)OC(N[C@@H](CC1)C[C@@H]1C(CC(C/C(/NC)=C(\C)/OC)=O)=O)=O WXEQJZLNVKZFOQ-ANPXMQTQSA-N 0.000 description 1
- CDEARGVHSFZVIU-WGSAOQKQSA-N CC(C)(C)OC(N[C@H](CC1)CC[C@@H]1S(Cc1c(C)[o]c(-c(cc2)ccc2C(OC)=O)n1)(=O)=O)=O Chemical compound CC(C)(C)OC(N[C@H](CC1)CC[C@@H]1S(Cc1c(C)[o]c(-c(cc2)ccc2C(OC)=O)n1)(=O)=O)=O CDEARGVHSFZVIU-WGSAOQKQSA-N 0.000 description 1
- BLAUQOBCGFPHMQ-IYNHQRNQSA-N CC/C=C\CC/C(/C[BrH]C)=C\CC Chemical compound CC/C=C\CC/C(/C[BrH]C)=C\CC BLAUQOBCGFPHMQ-IYNHQRNQSA-N 0.000 description 1
- UPRWLGMGHLXYJA-BVNZOPMMSA-N CC/C=C\[C@@](C)(CO)O/C(/C)=C(/CS)\NC Chemical compound CC/C=C\[C@@](C)(CO)O/C(/C)=C(/CS)\NC UPRWLGMGHLXYJA-BVNZOPMMSA-N 0.000 description 1
- XXEHJKXGCIHEGV-NSHDSACASA-N CCC[C@@H](CCS(CC(NC)=C(C)C)(=O)=O)N Chemical compound CCC[C@@H](CCS(CC(NC)=C(C)C)(=O)=O)N XXEHJKXGCIHEGV-NSHDSACASA-N 0.000 description 1
- QJANPLUJHVOAPG-UGIKXFJFSA-N CCO/C(/C)=C(/CS([C@H](CC1)CC[C@@H]1NC(OC(C)(C)C)=O)(=O)=O)\NC Chemical compound CCO/C(/C)=C(/CS([C@H](CC1)CC[C@@H]1NC(OC(C)(C)C)=O)(=O)=O)\NC QJANPLUJHVOAPG-UGIKXFJFSA-N 0.000 description 1
- RFEDQTSVZVRTGH-UHFFFAOYSA-N CN(C)Cc(cc1)ccc1Br Chemical compound CN(C)Cc(cc1)ccc1Br RFEDQTSVZVRTGH-UHFFFAOYSA-N 0.000 description 1
- QLAHZULAYAYUKZ-YHMJZVADSA-N C[C@H](CC1)CC1N1CCCC1 Chemical compound C[C@H](CC1)CC1N1CCCC1 QLAHZULAYAYUKZ-YHMJZVADSA-N 0.000 description 1
- NQRBZSIEDWNLHS-UHFFFAOYSA-N Cc1c(CS(c2ccc(C)cc2)(=O)=O)nc(-c(cc2)ccc2C(N(C)c2cccnc2)=O)[o]1 Chemical compound Cc1c(CS(c2ccc(C)cc2)(=O)=O)nc(-c(cc2)ccc2C(N(C)c2cccnc2)=O)[o]1 NQRBZSIEDWNLHS-UHFFFAOYSA-N 0.000 description 1
- LLUVMCMFZIZVTG-UHFFFAOYSA-N Cc1c(CS(c2ccc(CCN3CCOCC3)cc2)(=O)=O)nc(-c(cc2)ccc2C(O)=O)[o]1 Chemical compound Cc1c(CS(c2ccc(CCN3CCOCC3)cc2)(=O)=O)nc(-c(cc2)ccc2C(O)=O)[o]1 LLUVMCMFZIZVTG-UHFFFAOYSA-N 0.000 description 1
- VLLJJIRLYWXRBZ-UHFFFAOYSA-N Cc1c(CSc2ccc(C)cc2)nc(-c(cc2)ccc2C(NCc2cnccc2)=O)[o]1 Chemical compound Cc1c(CSc2ccc(C)cc2)nc(-c(cc2)ccc2C(NCc2cnccc2)=O)[o]1 VLLJJIRLYWXRBZ-UHFFFAOYSA-N 0.000 description 1
- KZZQCURODINAON-UHFFFAOYSA-N Cc1c(CSc2ccc(C)cc2)nc(-c(cc2)ccc2C(O)=O)[o]1 Chemical compound Cc1c(CSc2ccc(C)cc2)nc(-c(cc2)ccc2C(O)=O)[o]1 KZZQCURODINAON-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39195810P | 2010-10-11 | 2010-10-11 | |
| US61/391,958 | 2010-10-11 | ||
| US201161434976P | 2011-01-21 | 2011-01-21 | |
| US61/434,976 | 2011-01-21 | ||
| US201161475549P | 2011-04-14 | 2011-04-14 | |
| US61/475,549 | 2011-04-14 | ||
| PCT/US2011/055624 WO2012051117A2 (en) | 2010-10-11 | 2011-10-10 | Substituted benzamides and their uses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103327972A true CN103327972A (zh) | 2013-09-25 |
Family
ID=45938912
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011800595100A Pending CN103327972A (zh) | 2010-10-11 | 2011-10-10 | 取代的苯甲酰胺及其用途 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US9085570B2 (https=) |
| EP (1) | EP2627324A4 (https=) |
| JP (1) | JP2013539786A (https=) |
| KR (1) | KR20140027907A (https=) |
| CN (1) | CN103327972A (https=) |
| AU (1) | AU2011313853A1 (https=) |
| BR (1) | BR112013008898A2 (https=) |
| CA (1) | CA2814503A1 (https=) |
| WO (1) | WO2012051117A2 (https=) |
| ZA (1) | ZA201302854B (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012158691A1 (en) * | 2011-05-19 | 2012-11-22 | The Board Of Trustees Of The Leland Stanford Junior University | Anti-proliferative compounds and methods for using the same |
| US9296732B2 (en) | 2012-04-12 | 2016-03-29 | The Board Of Trustees Of The Leland Stanford Junior University | Substituted benzamides and their uses |
| WO2013182612A1 (en) | 2012-06-07 | 2013-12-12 | Bayer Pharma Aktiengesellschaft | Glucose transport inhibitors |
| WO2014134391A1 (en) | 2013-02-28 | 2014-09-04 | Bristol-Myers Squibb Company | Phenylpyrazole derivatives as potent rock1 and rock2 inhibitors |
| AR094929A1 (es) | 2013-02-28 | 2015-09-09 | Bristol Myers Squibb Co | Derivados de fenilpirazol como inhibidores potentes de rock1 y rock2 |
| WO2015078799A1 (en) * | 2013-11-27 | 2015-06-04 | Bayer Pharma Aktiengesellschaft | Glucose transport inhibitors |
| CN105829296A (zh) | 2013-12-18 | 2016-08-03 | 巴斯夫欧洲公司 | 带有亚胺衍生的取代基的唑类化合物 |
| WO2016202935A1 (en) | 2015-06-19 | 2016-12-22 | Bayer Pharma Aktiengesellschaft | Glucose transport inhibitors |
| CA3166630A1 (en) | 2020-01-03 | 2021-07-08 | Berg Llc | Polycyclic amides as ube2k modulators for treating cancer |
| CN116462606B (zh) * | 2022-01-12 | 2025-11-28 | 南京宁丹新药技术股份有限公司 | 一类酰胺衍生化合物及其用途 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1835934A (zh) * | 2003-01-17 | 2006-09-20 | 安斯泰来制药有限公司 | 作为环加氧酶抑制剂的噁唑衍生物 |
| WO2012100223A1 (en) * | 2011-01-21 | 2012-07-26 | John Irwin | Synthetic lethal targeting of glucose transport |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4172896A (en) | 1978-06-05 | 1979-10-30 | Dainippon Pharmaceutical Co., Ltd. | Methane-sulfonamide derivatives, the preparation thereof and composition comprising the same |
| GB9217295D0 (en) | 1992-08-14 | 1992-09-30 | Wellcome Found | Controlled released tablets |
| US5541231A (en) | 1993-07-30 | 1996-07-30 | Glaxo Wellcome Inc. | Stabilized Pharmaceutical |
| US5358970A (en) | 1993-08-12 | 1994-10-25 | Burroughs Wellcome Co. | Pharmaceutical composition containing bupropion hydrochloride and a stabilizer |
| GB9315856D0 (en) | 1993-07-30 | 1993-09-15 | Wellcome Found | Stabilized pharmaceutical |
| CN1087725C (zh) | 1994-03-25 | 2002-07-17 | 同位素技术有限公司 | 用氘代方法增强药物效果 |
| US6334997B1 (en) | 1994-03-25 | 2002-01-01 | Isotechnika, Inc. | Method of using deuterated calcium channel blockers |
| US6110973A (en) | 1998-01-29 | 2000-08-29 | Sepracor | Methods for treating obesity and weight gain using optically pure (-)-bupropion |
| US6835731B2 (en) | 2000-09-15 | 2004-12-28 | Anormed, Inc. | Chemokine receptor binding heterocyclic compounds |
| EA200400011A1 (ru) * | 2001-06-07 | 2004-06-24 | Эли Лилли Энд Компани | Модуляторы рецепторов, активируемых пролифераторами пероксисом (prar) |
| EP1369420A1 (en) * | 2002-06-06 | 2003-12-10 | Aventis Pharma Deutschland GmbH | Inhibitors of the GPib - vWF interaction |
| US7235558B2 (en) * | 2002-06-06 | 2007-06-26 | Sanofi-Aventis Deutschland Gmbh | Inhibitors of the GPIb—vWF interaction, their preparation and use |
| TW200505446A (en) | 2003-01-17 | 2005-02-16 | Fuj Isawa Pharmaceutical Co Ltd | Inhibitor of cox |
| EP1655283A1 (en) * | 2004-11-08 | 2006-05-10 | Evotec OAI AG | 11beta-HSD1 Inhibitors |
| US20080293711A1 (en) | 2007-03-08 | 2008-11-27 | Clark Michael P | Chemokine receptor modulators |
| WO2009097113A2 (en) | 2008-01-28 | 2009-08-06 | New York University | Oxazole and thiazole compounds as b-catenin modulators and uses thereof |
| US20110105436A1 (en) | 2008-03-10 | 2011-05-05 | Auckland Uniservices Limited | Heteroaryl compounds, compositions, and methods of use in cancer treatment |
| HRP20170357T1 (hr) | 2008-10-10 | 2017-05-05 | Vm Discovery, Inc. | Sastavi i postupci za liječenje poremećaja zbog konzumacije alkohola, bolova i ostalih bolesti |
| WO2010078408A1 (en) * | 2008-12-30 | 2010-07-08 | Biogen Idec Ma Inc. | Heteroaryl compounds useful as raf kinase inhibitors |
| WO2011011514A1 (en) * | 2009-07-21 | 2011-01-27 | The Board Of Trustees Of The Leland Stanford Junior University | Heteroaryl benzamides, compositions and methods of use |
| EP2305643A1 (en) * | 2009-10-02 | 2011-04-06 | Ikerchem, S.L. | New histone deacetylase inhibitors based simultaneously on trisubstituted 1h-pyrroles and aromatic and heteroaromatic spacers |
| WO2012158691A1 (en) * | 2011-05-19 | 2012-11-22 | The Board Of Trustees Of The Leland Stanford Junior University | Anti-proliferative compounds and methods for using the same |
| US9296732B2 (en) * | 2012-04-12 | 2016-03-29 | The Board Of Trustees Of The Leland Stanford Junior University | Substituted benzamides and their uses |
-
2011
- 2011-10-10 EP EP11833208.9A patent/EP2627324A4/en not_active Withdrawn
- 2011-10-10 CA CA2814503A patent/CA2814503A1/en not_active Abandoned
- 2011-10-10 JP JP2013533917A patent/JP2013539786A/ja active Pending
- 2011-10-10 US US13/878,682 patent/US9085570B2/en not_active Expired - Fee Related
- 2011-10-10 BR BR112013008898A patent/BR112013008898A2/pt not_active IP Right Cessation
- 2011-10-10 WO PCT/US2011/055624 patent/WO2012051117A2/en not_active Ceased
- 2011-10-10 AU AU2011313853A patent/AU2011313853A1/en not_active Abandoned
- 2011-10-10 KR KR1020137012143A patent/KR20140027907A/ko not_active Withdrawn
- 2011-10-10 CN CN2011800595100A patent/CN103327972A/zh active Pending
-
2013
- 2013-04-19 ZA ZA2013/02854A patent/ZA201302854B/en unknown
-
2015
- 2015-07-20 US US14/803,771 patent/US20150329503A1/en not_active Abandoned
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1835934A (zh) * | 2003-01-17 | 2006-09-20 | 安斯泰来制药有限公司 | 作为环加氧酶抑制剂的噁唑衍生物 |
| WO2012100223A1 (en) * | 2011-01-21 | 2012-07-26 | John Irwin | Synthetic lethal targeting of glucose transport |
Also Published As
| Publication number | Publication date |
|---|---|
| BR112013008898A2 (pt) | 2016-06-28 |
| JP2013539786A (ja) | 2013-10-28 |
| ZA201302854B (en) | 2014-07-25 |
| US9085570B2 (en) | 2015-07-21 |
| AU2011313853A1 (en) | 2013-05-02 |
| WO2012051117A2 (en) | 2012-04-19 |
| CA2814503A1 (en) | 2012-04-19 |
| WO2012051117A3 (en) | 2012-06-14 |
| US20150329503A1 (en) | 2015-11-19 |
| EP2627324A4 (en) | 2014-05-07 |
| US20140024649A1 (en) | 2014-01-23 |
| KR20140027907A (ko) | 2014-03-07 |
| EP2627324A2 (en) | 2013-08-21 |
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Application publication date: 20130925 |