CN103316227A - Medicine composition for treating rheumatic diseases in muscles and bones and preparation method thereof - Google Patents
Medicine composition for treating rheumatic diseases in muscles and bones and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a medicine composition for treating rheumatic diseases in muscles and bones and a preparation method thereof. A main laboratorial formula of the medicine composition is as follows: 17 traditional Chinese medicines including radix aconiti preparata, rhizoma corydalis, herba taxilli, long-noded pit viper, radix saposhnikoviae, radix clematidis, rhizoma drynariae, ginseng, pangolin, Chinese loive, panax pseudoginseng powder, medlar, corn cervi pantotrichum, liquorice, rhizoma gastrodiae, safflower and dipsacus root are processed into a compound Chinese medicine oral preparation. The medicine composition has an obvious effect in treating orthopedic diseases; and since the medicine composition is mainly prepared from the traditional Chinese medicines, toxic and side effects on human body are avoided. Clinical practice proves that more than 80 from over 100 patients treated by the medicine are restored completely by use of the medicine, the illness state of more than 20 patients is obviously improved, the number of patients completely not experiencing an effect is zero, and the total effective rate is 100%.
Description
Technical field
The invention belongs to the Chinese medicine preparation technical field, relate to the oral preparation of Chinese traditional medicinal for the treatment of orthopaedic disease, more specifically say a kind of pharmaceutical composition and preparation method that is used for the treatment of rheumatic muscles and bones disease.
Background technology
It is many that rheumatic muscles and bones disease produces reason, and rheumatism can comprise many diseases in fact, people know quite well rheumatic arthritis etc., also having the disease such as systemic lupus erythematosus (sle) also is rheumatismal type.So rheumatism can cause sizable harm in fact, the cause of disease of rheumatism is comparatively complicated, for example:
(1), infects.Rheumatism tends to fall ill because infect, but this point is easily ignored by the people.A lot of rheumatisms are relevant with infection.Relevant with the infection of A type Hemolytic streptococcus such as rheumatismal morbidity, ankylosing spondylitis is relevant with the Klebsiella pneumonia infection, and rheumatoid arthritis is relevant with infected by microbes.
(2), wind secretion, immune, hereditary etc.Also have in addition many factors all may become the cause of disease of rheumatism, relatively common are endocrine factors etc.Estrogen can stimulate the morbidity of rheumatoid arthritis, and this also is the reason of rheumatism morbidity.Dysimmunity is occupied critical role in the reason of rheumatism morbidity, many rheumatisms have at least partly cause to be caused by dysimmunity.Belong to autoimmune disease such as rheumatoid arthritis.Increasing data shows that rheumatism is relevant with inherited genetic factors.Rheumatoid arthritis, ankylosing spondylitis all have genetic predisposition, and gout, rheumatic fever and inherited genetic factors also have substantial connection.The reason of rheumatism morbidity also has other factors: as living in for a long time dark moist place, also be rheumatismal major reason, also having physical factor, chemical factor, organism quality etc. in addition also all is important risk factors.
(3) chronic lumbar muscle strain is common clinical, frequently-occurring disease, and pathogenic factors is more, cardinal symptom is that waist is ached, and in the daytime fatigue increases the weight of, and can alleviate after the rest, accumulates over a long period, can make myofibrosis, even tear on a small quantity, form cicatrix or fiber rope bar or adhesion, leave over the long-term chronic lumbago and backache.The lumbar muscle strain cause of disease comprises that the 3rd lumbar vertebra is the center that is positioned at the waist activity, it is again the most outstanding place of lumbar vertebra physiology lordosis, become lumbar vertebra anteflexion, after stretch, the hinge of left and right sides lateral bending and left rotation and right rotation activity, it the most mostly is the lumbar muscle strain cause of disease that its both sides transverse process end is subjected to the stress of tractive.
(4) outstanding, the hyperosteogeny of cone point dish etc. also is multiple disease clinically, and the cause of disease of prolapse of intervertebral disc has two: one, owing to being subject to suddenly external force or when frightening, making vertebra be subject to sprain and contusion and is shifted; The 2nd, because a certain position of life-time service (as stand, sit, look up at etc.) work or study, make vertebra form gradually the distortion displacement.Because vertebra or front or rear or left or dextroposition or left tilting, not on original due curvature line, make intervertebral disc all around stressed Bu Zhuo be extruded and deviate from.Owing to the vertebra displacement produces hyperosteogeny, be a kind of compensatory function of skeleton, belong to physiology's phenomenon of pathosis.And the cause of disease of scapulohumeral periarthritis, sciatica, numb hand and foot disease also has two kinds: a kind of is the surgery factor, and namely the nerve owing to compressing respective regions position after the vertebra displacement makes QI and blood can not unimpededly produce pain or numb hand and foot; The second is the internal medicine factor, and namely the caused obstruction of meridians and collaterals QI and blood of the damp and hot arthromyodynia of wind and cold is obstructed and produce pain or numb hand and foot.
In sum, can see that it is many that orthopaedic disease produces reason, this also is the main cause that people are difficult to carry out disease prevention.At present, there is this kind disease in a large number in China, and treats these diseases, can only take to take medicine or the method such as operation, and the medicine that China treats these diseases at present is not a lot, and curative effect neither be too desirable.
Summary of the invention
Main very undesirable to the present curative effect problem of the present invention on the basis of hereditary recipe, solves patient's gained disease with Chinese medicine treating both the principal and secondary aspects of a disease ground.A large amount of clinical trials prove that orthopaedic disease is had good curative effect.The present invention is the prescription of close biography treatment of successive dynasties orthopaedic disease, has passed through a lot of clinical verifications for the people, proves that selected Chinese medicine is harmless, and long-term taking can not produce any side effect.Its curative effect is that general medicine can not have.
For this reason, technical scheme disclosed by the invention is as follows:
A kind of pharmaceutical composition that is used for the treatment of rheumatic muscles and bones disease is characterized in that it is comprised of following compositions:
Radix Aconiti Preparata 20--30g, Rhizoma Corydalis 10--15g, Herba Taxilli 2--5g, Agkistrodon 35--45g,
Radix Saposhnikoviae 30--40g, Radix Clematidis 80--100g, bone be pure mend 10--15g, Radix Ginseng 40--50g,
Squama Manis 10--15g, Radix Paeoniae Alba 10--15g, Radix Notoginseng powder 40--50g, Fructus Lycii 50--60g,
Cornu Cervi Pantotrichum 10--15g, Radix Glycyrrhizae 30--45g, Rhizoma Gastrodiae 10--15g, Flos Carthami 30--45g,
Radix Dipsaci 8--12g.
The preferred pharmaceutical composition of the present invention is characterized in that it is comprised of following compositions:
Radix Aconiti Preparata 25--30g, Rhizoma Corydalis 12--15g, Herba Taxilli 2--5g, Agkistrodon 40--45g,
Radix Saposhnikoviae 35--40g, Radix Clematidis 85--100g, bone be pure mend 12--15g, Radix Ginseng 45--50g,
Squama Manis 12--15g, Radix Paeoniae Alba 10--15g, Radix Notoginseng powder 40--50g, Fructus Lycii 55--60g,
Cornu Cervi Pantotrichum 12--15g, Radix Glycyrrhizae 40--45g, Rhizoma Gastrodiae 12--15g, Flos Carthami 35--45g,
Radix Dipsaci 10--12g.
The present invention further discloses the preparation method that is used for the treatment of rheumatic muscles and bones disease medicament compositions, it is characterized in that being undertaken by following step:
(1) screening of medical material: choose the intact Chinese crude drug of high-quality, the medical material of choosing is got mixed powder through mechanical drying, pulverizing, mistake 100 purpose sieve series;
(3) mixed powder is directly incapsulated or the Mel of mixed powder with 3-5 parts is mixed, make pill.
Compositions of the present invention is oral formulations, is typically: capsule or pill.Such as 2000 in glue capsule, at every turn can be oral 3, but approximately 700 of pill agent, each oral one.
Need to prove: the selected Chinese medicine of the present invention, need want the certified products genuine article, otherwise curative effect will to reduce greatly through strict selection, such as a large amount of use vacations and of inferior quality Chinese herbal medicine, then can cause being of no curative effect.
Prescription mechanism of the present invention is:
(1) in this prescription, Radix Aconiti Preparata, Rhizoma Corydalis, Herba Taxilli, Agkistrodon, Radix Saposhnikoviae, the pure benefit of bone, Squama Manis etc. are the important drugs for the treatment of orthopaedic disease, other has some medicines such as Radix Ginseng, Cornu Cervi Pantotrichum etc., then be that the human immunologic function is improved, people's body constitution in the process of cure diseases is also well recovered.
(2) treating both the principal and secondary aspects of a disease, health is to resist the capital of disease, pith take the health-physical fitness that recovers the people as the treatment disease, allow the state of an illness obtain medical treatment on the basis of body constitution stalwartness, healing time is longer relatively, but after recovering body constitution be improved significantly, do not stay any sequela, and can be not repeatedly.
(3) give the bodily fuctions with total care, with the be discussed as foundation of Huangdi's Internal Classics to viscera, the treatment primary disease is taken into account other.
The main pharmacological property of the used Chinese medicine of the present invention is as follows:
Radix Aconiti Preparata: expelling wind and removing dampness, antalgic.Be used for anemofrigid-damp arthralgia, arthralgia, trusted subordinate's cold type of pain, colic of cold type is had a pain, narcotic analgesic.
Rhizoma Corydalis: be mainly used in all pain cards of stagnation of QI and blood.The stagnation of QI in the energy promoting the circulation of blood, therefore stasis in the gas is all pains about specially controlling all over the body.
Herba Taxilli: invigorating the liver and kidney, bone and muscle strengthening, wind-damp dispelling, antiabortive, main soreness of waist and knee joint, a little less than the muscles and bones flaccidity, limbs are hemiplegia, rheumatic arthralgia, head is wrong dizzy, frequent fetal movement, metrostaxis.Be used for rheumatic arthralgia, soreness of the waist and knees, muscles and bones is unable, and the metrorrhagia warp is many, blood leaking in gestation, frequent fetal movement, hypertension.
Agkistrodon: heat-clearing and toxic substances removing, the sharp Herba Hedyotidis Diffusae urine of invigorating blood circulation.Be used for tonsillitis, pharyngolaryngitis, urinary tract infection, pelvic inflammatory disease, appendicitis, hepatitis, bacillary dysentery, venom, tumor.Also can be used for alimentary tract cancer.
Radix Saposhnikoviae: removing dampness to relieve pain, relieving convulsion.Be mainly used in that headache, body due to the cold is painful, rheumatic arthralgia, headche due to wind-cold and toothache.
Squama Manis: blood circulation promoting and dispersing pathogen accumulation; The stimulating milk secretion of stimulating the menstrual flow; Eliminating carbuncle is burst hard.Main blood stasis amenorrhea; Lump in the abdomen; Rheumatic arthralgia; Agalactia; Carbuncle; Scrofula.
Rhizoma Drynariae: clinical Chinese medicine commonly used, can the kidney invigorating, invigorate blood circulation hemostasis.Clinically be usually used in controlling suffer from a deficiency of the kidney chronic diarrhea and lumbago, rheumatic arthralgia, toothache, tinnitus, traumatic injury sprain and contusion, bone injury, appendicitis, alopecia areata, clavus.Invigorate blood circulation to continue and hinder the kidney invigorating bone strengthening.
Radix Notoginseng powder: hemostasis, dissipating blood stasis, detumescence, analgesic therapy.Has the dissipating blood stasis hemostasis, the effect of subduing swelling and relieving pain.
Flos Carthami: promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.Be used for amenorrhea, dysmenorrhea, lochia, injury from falling down, skin infection swells and ache.
Radix Dipsaci: invigorating the liver and kidney; Bone and muscle strengthening; Blood circulation regulating; Continuous folding is hindered; End metrorrhagia.Be used for aching pain in waist and back; The podomere flaccidity syndrome and arthralgia syndrome; Fall pounce on wound, decrease muscle folding bone, red, metrorrhagia is leaked in fetal movement, seminal emission, leukorrhagia, carbuncle skin ulcer are swollen.Prepared RADIX DIPSACI with yellow rice wine is multiplex in rheumatic arthralgia, injury from falling down.Prepared RADIX DIPSACI with salt solution is multiplex in soreness of the waist and knees.
Radix Clematidis: hot, salty, temperature.Return urinary bladder channel.Main effect is wind-damp dispelling, removing obstruction in the collateral to relieve pain, and a fishbone or other bone caught in the throat disappears.
Radix Ginseng: but strongly invigorating primordial QI promote the production of body fluid admittedly take off, calm the nerves.Control impairment caused by overstrain deficient, lack of appetite, asthenia etc., in we, mainly help out, the orthopaedic diseases such as a lot of people's rheumatism and lumbar muscle strain, cone point dish are given prominence to, hyperosteogeny all are owing to due to all the year round fatigue, using Radix Ginseng can mend the patient and controlling the negative and positive deficiency, insufficiency of lung-QI, it is rebuild one's physical constitution, other medicines are better played a role.
The Radix Paeoniae Alba: the main yin fluid astringing that nourishes blood that rises, easing the affected liver to relieve pain, the suppressing the hyperactive liver sun waits effect.The suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, astringing YIN to stop sweating.Dizzy, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, spontaneous perspiration, night sweat are used for having a headache.Cooperate Radix Ginseng, mend the void of human body, and can reconcile cardiovascular system of human body and play analgesic activity.
Fructus Lycii: mainly play nourishing the liver and kidney, replenishing vital essence to improve eyesight.Be used for that asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, interior-heat are quenched one's thirst, blood deficiency and yellow complexion, blurred vision be not clear.
Cornu Cervi Pantotrichum: the health-care effect of Cornu Cervi Pantotrichum is very high, is good general tonic.Cornu Cervi Pantotrichum contains the aminoacid abundanter than Radix Ginseng, lecithin, vitamin and trace element etc.Cornu Cervi Pantotrichum is warm in nature and not dry, has to rouse oneself and improve body function, to patient after asthenia universalis, the prolonged illness, preferably health-care effect is arranged.Select Cornu Cervi Pantotrichum among the we, mainly get its invigorating kidney-YANG, mend marrow, bone and muscle strengthening, the pharmacological effect of transferring punching to appoint.
Radix Glycyrrhizae: Radix Glycyrrhizae and all medicines, separate hundred poison, be the famous large Chinese medicine material of China.Property is put down, is distinguished the flavor of and put down. GUIXIN, lung, spleen, stomach warp.Have invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, can remove phlegm and relieving cough, the function of relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.Be used for weakness of the spleen and stomach, lassitude, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, extremity contraction urgency, pain, carbuncle sore tumefacting virus, but and cushion toxicity, strong.
Rhizoma Gastrodiae: Rhizoma Gastrodiae embellishes but not dry, and the master enters Liver Channel, is longer than suppressing the hyperactive liver to relieve the wind syndrome, and the disease of all liver-wind stirring up internallys, the vertigo is no matter deficiency and excess is key medicine.The effect of Rhizoma Gastrodiae is mainly wind-damp dispelling, pain relieving, promoting flow of QI and blood.Use Rhizoma Gastrodiae among the we, mainly be for other medicine compatibility, more effectively bring into play the prescription effect.
The pharmacological effect of the above several main medications, when the treatment orthopaedic disease, compatibility plays a role mutually, mainly for the cause of disease, treating both the principal and secondary aspects of a disease, effective percentage can reach 100%.
The present invention further discloses and has been used for the treatment of the application of rheumatic muscles and bones disease medicament compositions in preparation treatment rheumatism, rheumatoid, fracture medicine.The present invention is the prescription of close biography treatment of successive dynasties orthopaedic disease, in the location, has passed through a lot of clinical verifications for the people, proves that selected Chinese medicine is harmless, and long-term taking can not produce any side effect.Its curative effect is that general medicine can not have.
The clinical trial that the present invention carries out mainly contains:
(1) rheumatic arthritis (RA) is the common clinical of the northern area of China, to form with joint synovitis disease, cellular infiltration, synovial membrane and ossa articularia pannus, finally cause articulation mechanism to destroy, cause that joint function disturbance is a kind of common autoimmune disease of main pathological change.Its clinical manifestation is take chronic progressive external symmetry arthralgia as main, and the cause of disease is not bright, there is no so far the method for radical cure.We summing up on the basis of clinical experience for many years, select to adopt rheumatic muscles and bones treatment RA to primary disease treatment, and curative effect is better.In more than 50 s rheumatic arthritis patients of this medicine treatment, fully with have more than 40 of this medicine rehabilitation, what the state of an illness had clear improvement has more than 10, and does not resultfully have fully, totally effective percentage 100%.
(2) sciatica is the pain symptom group on the sciatic nerve path.Sciatica is the pain along sciatic nerve path and areal area thereof, is owing to prolapse of lumbar intervertebral disc, wind and cold, pyriformis syndrome etc. cause.The Secondary Sciatic Pain main cause is for etiological treatment, and the cause of disease of primary sciatica is not bright, mainly is symptomatic treatment at present, and what have heals with medicine, and what have uses naturopathy.In 31 patients of this medicine treatment, with have 25 of this medicine rehabilitation, what the state of an illness had clear improvement has 6 fully, and does not resultfully have overall effective percentage 100% fully.
(3) the outstanding prolapse of lumbar intervertebral disc of waist point dish is the most common a kind of disease, and majority think that its pathogenic factor is the long-term pressurized degeneration of Lumbar Vertebral Canal inner tissue and the chronic inflammatory disease of the aseptic that causes.The general course of disease of this disease is longer, gradual increasing the weight of, and easily recurrence after the treatment.37 routine prolapse of lumbar intervertebral disc patients in the treatment of this medicine have taked traction, have massaged and composite treatment for oral administration, 25 routine patients are almost recovered (during draw) as a result, produce effects 11 examples, effective 9 examples of time medicine rehabilitation fully for oral administration, invalid 1 example, total effective rate 97.0%.Followed up a case by regular visits to 6～24 months after patient's recovery from illness, recover good, satisfactory effect.
Model case of the present invention:
Case 1, Li Ji it, the man, 62 years old, suffer from serious Hucklebone neuralgia for 3 years, taking this medicine namely had positive effect in rear 8 days, continued to take medicine three courses for the treatment of, returned to one's perfect health, so far again recurrence.
Case 2, Lv Baowei, the man, 58 years old, to suffer from serious rheumatic arthritis and reach 2 years, Severe Muscle atrophy phenomenon appears, and handicapped, very painful, take this medicine three courses for the treatment of, return to one's perfect health, so far not again recurrence.
Case 3, Jia Shi good fortune, the man, 65 years old, suffer from outstanding 2 years of waist point dish, take this medicine three courses for the treatment of, return to one's perfect health, so far not again recurrence.
Case 4: Hu Tianrong, the woman, 54 years old, suffer from for many years lumbago and skelalgia, can not dry weight live, can only have a rest when serious.Take this medicine and namely saw obvious curative effects in rear seven days, period in a medicine is pain no longer, and activity is also very normal, through taking medicine three courses for the treatment of, be almost recovered, after have no recurrence.
Case 5: Song Fuquan, the man, 54 years old, suffer from and strand to judge downright bad sick 1 year and have a surplus, can be movable but can not dry weight live, after taking this medicine 5 days positive effect is arranged, continue medication two wheat harvesting periods, be almost recovered, after again recurrence.
This prescription has a clear superiority in the disease of some bad processing for the treatment of, generally all is within a week positive effect to be arranged, as long as adhere to using this medicine, generally disease can both be cured, and does not remain in office what sequela.
The pharmaceutical composition advantage that the present invention treats rheumatic muscles and bones disease is:
(1) some Chinese medicines have the effect of obvious antirheumatic orthopaedic disease, and other has some Chinese medicines that human body is had obviously has obvious nourishing to take good care of effect to human body, mutually replenish, and give full play to the pharmacological property of each medicine, have remedied the deficiency of each medicine.
(2) in the compatibility of each medicine, both heavily treatment reset to be supported again, the side effect that alleviates to greatest extent some medicines, in treatment, make human body get well, strong, reach the effect for the treatment of both the principal and secondary aspects of a disease.
(3) increase immune function of human body in the process of controlling, make the people when disease is good, strengthen again body constitution, avoid the weak situation of the good body of disease to occur.
The specific embodiment
Below in conjunction with embodiment the present invention is described, the scheme of embodiment described here does not limit the present invention, one of skill in the art can make improvements and change according to spirit of the present invention, described these improvement and variation all should be considered as within the scope of the invention, and scope of the present invention and essence are limited by claim.The used various Chinese crude drugs of the present invention, raw material, reagent all have commercially available.
Embodiment 1
Radix Aconiti Preparata 20g, Rhizoma Corydalis 10g, Herba Taxilli 2g, Agkistrodon 35g, Radix Saposhnikoviae 30g, Radix Clematidis 80g,
Bone is pure mend 15g, Radix Ginseng 50g, Squama Manis 15g, Radix Paeoniae Alba 15g, Radix Notoginseng powder 50g, Fructus Lycii 60g,
Cornu Cervi Pantotrichum 10g, Radix Glycyrrhizae 30g, Rhizoma Gastrodiae 10g, Flos Carthami 30g, Radix Dipsaci 8g.
Embodiment 2
Radix Aconiti Preparata 30g, Rhizoma Corydalis 150g, Herba Taxilli 4g, Agkistrodon 45g, Radix Saposhnikoviae 40g, Radix Clematidis 100g,
Bone is pure mend 10g, Radix Ginseng 40g, Squama Manis 10g, Radix Paeoniae Alba 10g, Radix Notoginseng powder 40g, Fructus Lycii 50g,
Cornu Cervi Pantotrichum 15g, Radix Glycyrrhizae 45g, Rhizoma Gastrodiae 15g, Flos Carthami 45g, Radix Dipsaci 12g.
Embodiment 3
Radix Aconiti Preparata 30g, Rhizoma Corydalis 15g, Herba Taxilli 5g, Agkistrodon 40g, Radix Saposhnikoviae 35g, Radix Clematidis 100g,
Pure 15g, Radix Ginseng 50g, Squama Manis 15g, Radix Paeoniae Alba 15g, Radix Notoginseng powder 50g, Fructus Lycii 60g, Cornu Cervi Pantotrichum 15g, Radix Glycyrrhizae 40g, Rhizoma Gastrodiae 15g, Flos Carthami 40g, the Radix Dipsaci 12g of mending of bone.
Embodiment 4
Radix Aconiti Preparata 25g, Rhizoma Corydalis 12g, Herba Taxilli 2g, Agkistrodon 45g, Radix Saposhnikoviae 40g, Radix Clematidis 85g, bone be pure mend 12g, Radix Ginseng 45g, Squama Manis 12g, Radix Paeoniae Alba 10g, Radix Notoginseng powder 40g, Fructus Lycii 55g,
Cornu Cervi Pantotrichum 12-g, Radix Glycyrrhizae 45g, Rhizoma Gastrodiae 12g, Flos Carthami 45g, Radix Dipsaci 10g.
The preparation method of embodiment 1-4:
(1) screening of medical material: choose the intact Chinese crude drug of high-quality, the medical material of choosing is obtained mixed powder through mechanical drying, pulverizing, mistake 80 purpose sieves;
(3) mixed powder is directly incapsulated or mixed powder is mixed with Mel, make pill, Mel requires to select the pure honey product of high-quality, and is ropy also effective in cure, but not as pure honey good.(addition of Mel is conventional addition).
The present invention is in specific implementation process, and selected medicine can suitably be added and subtracted according to various orthopaedic disease, and is different even dose uses within not breaking away from above-mentioned claim, is equal to modifications, should can be regarded as the technical solution of the present invention scope.
Claims (7)
1. pharmaceutical composition that is used for the treatment of rheumatic muscles and bones disease is characterized in that it is comprised of following compositions:
Radix Aconiti Preparata 20--30g, Rhizoma Corydalis 10--15g, Herba Taxilli 2--5g, Agkistrodon 35--45g,
Radix Saposhnikoviae 30--40g, Radix Clematidis 80--100g, bone be pure mend 10--15g, Radix Ginseng 40--50g,
Squama Manis 10--15g, Radix Paeoniae Alba 10--15g, Radix Notoginseng powder 40--50g, Fructus Lycii 50--60g,
Cornu Cervi Pantotrichum 10--15g, Radix Glycyrrhizae 30--45g, Rhizoma Gastrodiae 10--15g, Flos Carthami 30--45g,
Radix Dipsaci 8--12g.
2. the pharmaceutical composition described in the claim 1 is characterized in that it is comprised of following compositions:
Radix Aconiti Preparata 25--30g, Rhizoma Corydalis 12--15g, Herba Taxilli 2--5g, Agkistrodon 40--45g,
Radix Saposhnikoviae 35--40g, Radix Clematidis 85--100g, bone be pure mend 12--15g, Radix Ginseng 45--50g,
Squama Manis 12--15g, Radix Paeoniae Alba 10--15g, Radix Notoginseng powder 40--50g, Fructus Lycii 55--60g,
Cornu Cervi Pantotrichum 12--15g, Radix Glycyrrhizae 40--45g, Rhizoma Gastrodiae 12--15g, Flos Carthami 35--45g,
Radix Dipsaci 10--12g.
3. the Chinese medicine composition described in the claim 1, compositions wherein is oral formulations.
4. the pharmaceutical composition described in the claim 3, oral formulations wherein is capsule or pill.
5. the described preparation method that is used for the treatment of rheumatic muscles and bones disease medicament compositions of claim 1-2 is characterized in that being undertaken by following step:
(1) screening of medical material: choose the intact Chinese crude drug of high-quality, the medical material of choosing is obtained mixed powder through mechanical drying, pulverizing, mistake 100 purpose sieves;
(3) mixed powder is directly incapsulated or mixed powder is mixed with Mel, make pill.
6. the described rheumatic muscles and bones disease medicament compositions that is used for the treatment of of claim 1 is preparing the application for the treatment of in the rheumatic muscles and bones disease medicament.
7. the orthopaedic diseases such as fracture that application claimed in claim 6, rheumatic muscles and bones disease wherein refer to that Hucklebone neuralgia, rheumatic arthritis, waist point dish are outstanding, lumbar muscle strain, femur head necrosis, hyperosteogeny, scapulohumeral periarthritis, tenosynovitis and contingency cause.
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Application publication date: 20130925 |