CN103313719A - 用于治疗结肠直肠癌的peg或peg嵌段共聚物 - Google Patents

用于治疗结肠直肠癌的peg或peg嵌段共聚物 Download PDF

Info

Publication number
CN103313719A
CN103313719A CN201180064013XA CN201180064013A CN103313719A CN 103313719 A CN103313719 A CN 103313719A CN 201180064013X A CN201180064013X A CN 201180064013XA CN 201180064013 A CN201180064013 A CN 201180064013A CN 103313719 A CN103313719 A CN 103313719A
Authority
CN
China
Prior art keywords
peg
composition
crc
mannitol
block copolymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201180064013XA
Other languages
English (en)
Chinese (zh)
Inventor
P·斯坦因
I·考克斯
S·史密斯
L·琼斯
J·普莱斯尔
C·德弗里斯
R·查尔顿
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Norgine BV
Original Assignee
Norgine BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Norgine BV filed Critical Norgine BV
Publication of CN103313719A publication Critical patent/CN103313719A/zh
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A61K31/77—Polymers containing oxygen of oxiranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
CN201180064013XA 2010-11-04 2011-11-04 用于治疗结肠直肠癌的peg或peg嵌段共聚物 Pending CN103313719A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB1018650.0 2010-11-04
GBGB1018650.0A GB201018650D0 (en) 2010-11-04 2010-11-04 Methods and compositions
US41212810P 2010-11-10 2010-11-10
US61/412128 2010-11-10
PCT/GB2011/001561 WO2012059725A1 (en) 2010-11-04 2011-11-04 Peg or peg block copolymers for treating colorectal cancer

Publications (1)

Publication Number Publication Date
CN103313719A true CN103313719A (zh) 2013-09-18

Family

ID=43414365

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201180064013XA Pending CN103313719A (zh) 2010-11-04 2011-11-04 用于治疗结肠直肠癌的peg或peg嵌段共聚物

Country Status (22)

Country Link
US (2) US20130216493A1 (cg-RX-API-DMAC7.html)
EP (1) EP2635289B1 (cg-RX-API-DMAC7.html)
JP (1) JP5917537B2 (cg-RX-API-DMAC7.html)
KR (1) KR20130109171A (cg-RX-API-DMAC7.html)
CN (1) CN103313719A (cg-RX-API-DMAC7.html)
AR (1) AR083770A1 (cg-RX-API-DMAC7.html)
AU (1) AU2011324996B2 (cg-RX-API-DMAC7.html)
BE (1) BE1019494A3 (cg-RX-API-DMAC7.html)
BR (1) BR112013011012A2 (cg-RX-API-DMAC7.html)
CA (1) CA2816839A1 (cg-RX-API-DMAC7.html)
EA (1) EA201300540A1 (cg-RX-API-DMAC7.html)
ES (1) ES2401269B1 (cg-RX-API-DMAC7.html)
GB (1) GB201018650D0 (cg-RX-API-DMAC7.html)
MX (1) MX349690B (cg-RX-API-DMAC7.html)
MY (1) MY163067A (cg-RX-API-DMAC7.html)
NL (1) NL2007715C2 (cg-RX-API-DMAC7.html)
NZ (1) NZ611145A (cg-RX-API-DMAC7.html)
SG (1) SG189533A1 (cg-RX-API-DMAC7.html)
TW (1) TWI606832B (cg-RX-API-DMAC7.html)
UA (1) UA107998C2 (cg-RX-API-DMAC7.html)
WO (1) WO2012059725A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201304052B (cg-RX-API-DMAC7.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113490501A (zh) * 2019-03-05 2021-10-08 陶氏环球技术有限责任公司 用于诱导胱天蛋白酶活性的聚乙二醇衍生物

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI535461B (zh) 2011-03-11 2016-06-01 諾金私人有限公司 結腸清潔溶液、用於製備該溶液之組成物、包含該組成物或溶液之套組、與製備該溶液之方法
BR112015005270B1 (pt) 2012-09-11 2022-11-01 Norgine Bv Composição para mistura com água, solução de limpeza de cólon, seus usos e seu kit
AR093153A1 (es) * 2012-10-26 2015-05-20 Northshore Univ Healthsystem Composiciones que comprenden polietilenglicol para la terapia del carcinoma de celulas escamosas de cabeza y cuello
CN103083733A (zh) * 2013-02-19 2013-05-08 华熙福瑞达生物医药有限公司 一种医用体腔器械导入水性润滑剂
WO2020180581A1 (en) 2019-03-05 2020-09-10 Dow Global Technologies Llc Inducing caspase activity
EP3934661B1 (en) * 2019-03-05 2025-04-02 Dow Global Technologies LLC Inducing caspase activity for treating colorectal cancer with polymers

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010051659A1 (en) * 1998-10-27 2001-12-13 Denis Corpet Non-fermented osmotic laxative and method for treating and preventing colorectal cancers

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2006244112B2 (en) * 2005-05-06 2011-02-17 Salix Pharmaceuticals, Inc. Polyethylene glycol colonic purgative composition
US8457025B2 (en) * 2009-08-28 2013-06-04 Telefonaktiebolaget L M Ericsson (Publ) Method and network node for selecting a network prefix to be advertised in a communication network

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010051659A1 (en) * 1998-10-27 2001-12-13 Denis Corpet Non-fermented osmotic laxative and method for treating and preventing colorectal cancers

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113490501A (zh) * 2019-03-05 2021-10-08 陶氏环球技术有限责任公司 用于诱导胱天蛋白酶活性的聚乙二醇衍生物
CN113490501B (zh) * 2019-03-05 2024-05-24 陶氏环球技术有限责任公司 用于诱导胱天蛋白酶活性的聚乙二醇衍生物

Also Published As

Publication number Publication date
WO2012059725A8 (en) 2013-05-30
WO2012059725A1 (en) 2012-05-10
MY163067A (en) 2017-08-15
TWI606832B (zh) 2017-12-01
MX2013004963A (es) 2013-08-27
EA201300540A1 (ru) 2013-09-30
BE1019494A3 (fr) 2012-07-03
AU2011324996A1 (en) 2013-05-02
KR20130109171A (ko) 2013-10-07
AU2011324996B2 (en) 2015-10-08
ZA201304052B (en) 2014-02-26
JP5917537B2 (ja) 2016-05-18
UA107998C2 (uk) 2015-03-10
NZ611145A (en) 2015-07-31
NL2007715A (en) 2012-05-07
US20160228467A1 (en) 2016-08-11
CA2816839A1 (en) 2012-05-10
EP2635289A1 (en) 2013-09-11
SG189533A1 (en) 2013-05-31
NL2007715C2 (en) 2012-10-16
MX349690B (es) 2017-08-09
ES2401269B1 (es) 2014-02-19
GB201018650D0 (en) 2010-12-22
AR083770A1 (es) 2013-03-20
BR112013011012A2 (pt) 2016-08-23
EP2635289B1 (en) 2020-03-11
US20130216493A1 (en) 2013-08-22
JP2013544809A (ja) 2013-12-19
TW201304785A (zh) 2013-02-01
ES2401269A1 (es) 2013-04-18

Similar Documents

Publication Publication Date Title
EP2635289B1 (en) Peg or peg block copolymers for treating colorectal cancer
JP5872573B2 (ja) ポリエチレングリコール含有製剤
Kienzle-Horn et al. Comparison of bisacodyl and sodium picosulphate in the treatment of chronic constipation
US20230190662A1 (en) Efficacy of a Gastro-Retentive Bile Acid Sequestrant Dosage Form
Chan et al. Randomized single-blind clinical trial of a rapid colonic lavage solution (Golytely) vs. standard preparation for barium enema and colonoscopy
JP2013540726A (ja) 便秘薬
Van der Linden et al. Fluoroquinolone use and the change in incidence of tendon ruptures in the Netherlands
IL225891A (en) Peg or block peg copolymers for the treatment of colorectal cancer
Gerbino et al. Antacids and laxatives for symptomatic relief in the elderly
Patel Development of Novel Sustained Release Formulations for Older Adults With Swallowing Difficulties
Jaiswal et al. Research Article Effectiveness in Bowel Cleansing and Patient Tolerability of Polyethylene Glycol versus Sodium Picosulphate in Patients Undergoing Colonoscopy
WO2016040733A1 (en) Sulfate salt solution laxative compositions and methods of use thereof

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C12 Rejection of a patent application after its publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20130918