CN103298454B - 取代二氨基嘌呤的药物制剂 - Google Patents

取代二氨基嘌呤的药物制剂 Download PDF

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Publication number
CN103298454B
CN103298454B CN201180062649.0A CN201180062649A CN103298454B CN 103298454 B CN103298454 B CN 103298454B CN 201180062649 A CN201180062649 A CN 201180062649A CN 103298454 B CN103298454 B CN 103298454B
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pharmaceutical preparation
amino
weight
compound
tautomer
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CN103298454A (zh
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斯恩尼瓦斯·S·巴特
晓忠·梁
安东尼·图蒂诺
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Signal Pharmaceuticals LLC
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Signal Pharmaceuticals LLC
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    • AHUMAN NECESSITIES
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    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
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    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/286Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
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    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
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CN201180062649.0A 2010-10-25 2011-10-24 取代二氨基嘌呤的药物制剂 Expired - Fee Related CN103298454B (zh)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US40629210P 2010-10-25 2010-10-25
US61/406,292 2010-10-25
US201161481378P 2011-05-02 2011-05-02
US61/481,378 2011-05-02
US201161528427P 2011-08-29 2011-08-29
US61/528,427 2011-08-29
US201161537963P 2011-09-22 2011-09-22
US61/537,963 2011-09-22
PCT/US2011/057460 WO2012061061A1 (en) 2010-10-25 2011-10-24 Pharmaceutical formulations of a substituted diaminopurine

Publications (2)

Publication Number Publication Date
CN103298454A CN103298454A (zh) 2013-09-11
CN103298454B true CN103298454B (zh) 2016-04-27

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US (2) US8603527B2 (https=)
EP (1) EP2632439B1 (https=)
JP (2) JP2013544239A (https=)
KR (1) KR20130142141A (https=)
CN (1) CN103298454B (https=)
AU (1) AU2011323807B2 (https=)
WO (1) WO2012061061A1 (https=)

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