CN103284895B - Essence lotion with slow release function and preparation method thereof - Google Patents

Essence lotion with slow release function and preparation method thereof Download PDF

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Publication number
CN103284895B
CN103284895B CN201210050789.2A CN201210050789A CN103284895B CN 103284895 B CN103284895 B CN 103284895B CN 201210050789 A CN201210050789 A CN 201210050789A CN 103284895 B CN103284895 B CN 103284895B
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water
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CN103284895A (en
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姜宁
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SHANGHAI LANACE BIOTECHNOLOGY CO Ltd
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SHANGHAI LANACE BIOTECHNOLOGY CO Ltd
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Abstract

The invention discloses essence lotion with a slow release function and a preparation method thereof. The essence lotion comprises macroscopic essence micro-capsule particles, so that the ingredients are more stable and the essence lotion is unlikely to be oxidized. Since caesalpinia spinosa extractive and saussurea involucrata extractive are utilized as main active substances and the slow release technology is combined, the prepared essence lotion can slowly release the active substances and form a three-dimensional netty structural membrane on the skin surface, and the membrane can not only increase the moisture retention effect, but also ensure free breath of the skin, increase the exchange between the skin cells and the outside, improve the skin metabolism, increase the activity of the skin cells and increase the moisture content of the skin.

Description

There is elite water of slow-release function and preparation method thereof
Technical field
The present invention relates to a kind of astringent, be specifically related to a kind of astringent with moistening effect.
Background technology
In recent years, along with the development of cosmetics and women are for beautiful demand, skin care item were pursued by people more and more.Consumer can be according to the product of own skin type selection different efficacies, and moisturizing is exactly one wherein, is also most critical in the base program of skin protection.As you know, carry out skin moisture-keeping work, skin degree of hydration is full, so other skin problem is all right has solved.From skin-protection product, the astringent skin-protection product that is absolutely necessary.Now the astringent on market comes point can be divided into thin skin water from function, toner/smoothing toner, and astringent, control profit etc., from the outward appearance of product, has transparently, translucent, has band color, not colored, has containing petalled etc.Whatsoever cosmetics or skin care item, as long as the packaging of product is not vacuum, while opening and using, product is all oxidized at every turn, the effect of product is all being successively decreased at every turn, and the lasting moistening effect of existing product is also undesirable.
Summary of the invention
The object of the invention is to solve above-mentioned the deficiencies in the prior art, provide a kind of for skin protection, skin care, and the elite water of tool slow-release function and preparation method thereof, described elite water comprise macroscopic elite microcapsule granule, the composition more stable active component being not easy in oxidized, product can slowly discharge, and improved greatly moistening effect, each result of use is all the same with result of use first, greatly strengthens the improvement effect of product for skin.Described elite microcapsule is the microcapsule that comprises energy elite, and can slowly discharge the energy elite comprising with each use, and in the time that elite water uses, the energy elite in elite microcapsule granule also just in time discharges complete.
The present invention uses following technical scheme for achieving the above object:
There is an elite water for slow-release function, the component that comprises following percentage by weight:
EDETATE SODIUM (disodiumedetate): 0.05%-0.1%,
Allantoin: 0.1%-0.5%, butanediol: 2%-6%,
Glycerol: 1%-8%, glycerol acrylate-acrylic copolymer: 0.5%-3%,
Carbomer: 0.01%-0.15%, Herba Saussureae Involueratae extract: 1%-20%, preferably 8%,
Caesalpinia spinosaKuntze extract: 1%-20%, preferably 8%, Aloe vulgaris leaf extract: 0.5%-8%,
Anjidew NL50 (pyrrolidone sodium carboxylate), carbamide, lactic acid, caprylyl glycol, hyaluronate sodium, 1,2-hexanediol and urine
The mixture A:0.5%-2% of Bursin composition,
Triethanolamine: 0.01%-0.15%, diazolidinyl urea: 0.1%-0.6%,
Styrene And Chloroalkyl Acrylates and cinnamic acrylic ester analog copolymer: 0.01%-0.1%,
The mixture B:0.5%-3.0% of lactose, cellulose and toner composition,
The mixture C of lactose and cellulose composition: 0.5%-3.0%,
Trehalose: 0.5%-3.0%, Hamamelis virginiana extract: 0.5%-6%,
Pantothenylol: 0.1%-1.0%, Flos Inulae extract: 0.5%-8%,
Beta glucan: 0.5%-5%, castor oil hydrogenated: 0.1%-0.6%,
Essence: 0.01%-0.1%, and surplus deionized water.
The example of water of the present invention comprises: be applicable to any water of cosmetic technology, as deionized water etc.
Glycerol acrylate-acrylic copolymer of the present invention is the glycerol acrylate-acrylic copolymer that is applicable to cosmetic technology.
Styrene-propene acid copolymer of the present invention is the styrene-propene acid copolymer that is applicable to cosmetic technology.
Institute of the present invention cinnamic acrylic ester analog copolymer is the cinnamic acrylic ester analog copolymer that is applicable to cosmetic technology.
The example of essence of the present invention comprises: any essence that is applicable to cosmetic technology.
The example of toner of the present invention comprises: any toner that is applicable to cosmetic technology.
The main component of Herba Saussureae Involueratae extract of the present invention is: all water soluble ingredients.
The main component of Caesalpinia spinosaKuntze extract of the present invention is: all water soluble ingredients.
The main component of Aloe vulgaris leaf extract of the present invention is: all water soluble ingredients.
The main component of Hamamelis virginiana extract of the present invention is: all water soluble ingredients.
The main component of Flos Inulae extract of the present invention is: all water soluble ingredients.
Carbomer of the present invention is any carbomer that is applicable to cosmetic technology.
Beta glucan of the present invention is any beta glucan that is applicable to cosmetic technology.
Anjidew NL50 of the present invention, carbamide, lactic acid, caprylyl glycol, hyaluronate sodium, 1, in the mixture A of 2-hexanediol and allantoin composition, the weight percentage of each component is (by total restatement of this mixture): carbamide 10-25%, lactic acid 5-10%, pungent sweet sour 0.1-1%, hyaluronate sodium 0.1-1%, allantoin 0.1-1%, 1,2-hexanediol 0.1-1%, Anjidew NL50 5-10%, surplus is water.
Lactose, cellulose and the mixture B of toner composition and the weight percentage of the mixed each component of Caesalpinia spinosaKuntze extract are (by mixed total restatement): lactose 20-35%, cellulose 35-50%, toner 0.1-5%, surplus is Caesalpinia spinosaKuntze extract.
The mixture C of lactose and cellulose composition and the weight percentage of the mixed each component of Herba Saussureae Involueratae extract are (by mixed total restatement): lactose 20-35%, and cellulose 35-50%, surplus is Herba Saussureae Involueratae extract.
Preferably, Herba Saussureae Involueratae extract described in the present invention: the weight ratio of Caesalpinia spinosaKuntze extract is 1: 1-6: 1, preferably 1: 1.
The preparation method that the invention also discloses described elite water, comprises the following steps:
1, the preparation process of elite microcapsule: (whole preparation process requires on smooth clean experimental operation table, and indoor temperature is 25 DEG C of left and right, and relative humidity carries out under the condition of 35% left and right.)
Preformulation: the preparation of Caesalpinia spinosaKuntze microcapsule: take a certain amount of cellulose, add 5 times of amount distilled water, in room temperature underlying colloid mill, and (amount adding is cellulosic 1/2nd, and the weight concentration of solution is: 5%) to add Caesalpinia spinosaKuntze extract solution, the mixing of fully milling, machine intimate residual fraction repeatedly cleans on a small quantity with distilled water, and washing liquid is incorporated to pastel, the washing with alcohol that decompress filter is also 95% by purity 3 times, cold drying, obtains white powder; Then at room temperature lactose, toner are joined in white powder; stir; speed is moderate; can not be too fast, then the powder body of mix homogeneously is put into granulator and carry out pelletize, then gained granule is laid in a square position; spread evenly; put into drying baker and be dried, temperature is 35-40 DEG C, 24 hours time.Place stand-by.
The preparation of Herba Saussureae Involueratae microcapsule: method is with the preparation method of Caesalpinia spinosaKuntze microcapsule, and difference is being changed to the Caesalpinia spinosaKuntze extract in Caesalpinia spinosaKuntze microcapsule Herba Saussureae Involueratae (SAUSSUREA INVOLUCRATA) extract,, other is identical, without toner.
2, the preparation of elite water: by the percentage by weight of described component, under room temperature, deionized water, EDETATE SODIUM, allantoin, butanediol, glycerol, glycerol acrylate-acrylic copolymer and carbomer (from deionized water to carbomer) are added in vacuum emulsifying pot successively, then homogenizing is uniformly dispersed (preferably homogenizing speed be 2000-2500 rev/min, the time is 5 minutes) raw material.Stirring is warming up to 80 DEG C, and (preferably mixing speed is: 30-40 rev/min); Add triethanolamine to stir, 80 DEG C are incubated 25 minutes; Then be cooled to 55 DEG C and add successively trehalose, Hamamelis virginiana extract, pantothenylol, Caesalpinia spinosaKuntze extract, Herba Saussureae Involueratae extract, Flos Inulae extract, Aloe vulgaris leaf extract, Anjidew NL50, carbamide, lactic acid, caprylyl glycol, hyaluronate sodium, 1,2-hexanediol, allantoin and beta glucan, stirring, (preferably mixing speed is: 30-40 rev/min); Be cooled to 45 DEG C and add diazolidinyl urea, Styrene And Chloroalkyl Acrylates (ester) analog copolymer, castor oil hydrogenated and essence, stirring, (preferably mixing speed is: 30-40 rev/min); Be cooled to 40 DEG C, (preferably mixing speed is: 20--30 rev/min), then add the above-mentioned pre-assigned elite microcapsule that shifts to an earlier date, stir to slow down mixing speed.
Elite microcapsule granule in the present invention is a kind of clathrate class organic crystal, in its structure, contain Liang Zhong structural units, be that clathrate is made up of two kinds of compounds: a kind of is other compounds can be imprisoned to the compound in its structural framework hole, is called inclusion agents or host molecule; Another kind is the compound being trapped in hole or the duct of inclusion agents structure, is called by inclusion agents or guest molecule.The size of guest molecule is subject to the restriction of physical dimension and the shape in inclusion agents hole.The composition of clathrate (inclusion agents with by the ratio of inclusion agents) is determined by the space number that can provide utilization in skeleton.The forties in 20th century, H.M. Bao Weir utilized X-ray diffraction method to understand fully in clathrate, between host molecule and guest molecule, conventionally not form strong chemical bond, main in clathrate, the original chemical property of guest molecule is constant, in most of clathrates, between host molecule and guest molecule, combine with van der waals force or hydrogen bond.In the present invention, capsule material is cellulose, and the capsule heart is active component, and granule is that low temperature adds, and active component slow release out.
The elite water in the present invention with slow-release function has following advantage: 1, elite water of the present invention is compared with existing like product, there is higher moistening effect, according to the test result of SKIN-CT, elite water of the present invention can increase by 56.7% product moistening effect after 14 days.2, the combination of composition of the present invention and content thereof can make the surface of skin form a kind of tridimensional network film, such film not only can make moistening effect increase, and can make skin freely breathe, increase Skin Cell and extraneous exchanging, increase the metabolism of skin, the vigor of skin cell is increased.Increase the moisture of skin, increase the degree of hydration of skin, increase the smooth sophistication of skin, accelerate the metabolism of cell, reduce the decortication of skin, the water profit that skin is become is penetrating, and exquisiteness is flexible.
Detailed description of the invention
In this detailed description of the invention, the physicochemical characteristic of glycerol acrylate-acrylic copolymer used is: PH (20-25 DEG C) 5-6; Viscosity (20-25 DEG C) 200,000-400,000 CPS; Refractive index (20-25 DEG C) 1.415-1.435; Density is 1.2-1.3g/cc; The physicochemical characteristic of Styrene And Chloroalkyl Acrylates used (ester) copolymer is: particle diameter is 0.17 micron; PH (20-25 DEG C) 2.0-3.5; Viscosity (20-25 DEG C) is less than 100CPS; Solid content is 40%; The relative molecular mass of carbomer used is 4,000,000; The molecular weight of beta glucan used is between 150,000-160,000.
embodiment 1-5: preparation has the elite water of slow-release function
The operating procedure of embodiment 1-5 is:
The preparation of microcapsule: (whole preparation process requires on smooth clean experimental operation table, and indoor temperature is 25 DEG C of left and right, and relative humidity carries out under the condition of 35% left and right.)
Preformulation: the preparation of Caesalpinia spinosaKuntze microcapsule: take a certain amount of cellulose, add 5 times of amount distilled water, in room temperature underlying colloid mill, and (amount of the Caesalpinia spinosaKuntze extract adding is cellulosic 1/2nd, and the concentration of solution is: 5%) to add the aqueous solution of Caesalpinia spinosaKuntze extract, the mixing of fully milling, machine intimate residual fraction repeatedly cleans on a small quantity with distilled water, and washing liquid is incorporated to pastel, the washing with alcohol that decompress filter is also 95% by purity 3 times, cold drying, obtains white powder; Then at room temperature lactose, toner are joined in white powder; stir; speed is moderate; can not be too fast, then the powder body of mix homogeneously is put into granulator and carry out pelletize, then gained granule is laid in a square position; spread evenly; put into drying baker and be dried, temperature is 35-40 DEG C, 24 hours time.Place stand-by.
The preparation of Herba Saussureae Involueratae microcapsule: method is with the preparation method of Caesalpinia spinosaKuntze microcapsule, and difference is being changed to Caesalpinia spinosaKuntze extract Herba Saussureae Involueratae (SAUSSUREA INVOLUCRATA) extract,, other is identical, without toner.
Under room temperature, deionized water, EDETATE SODIUM, allantoin, butanediol, glycerol, glycerol acrylate-acrylic copolymer and carbomer (from deionized water to carbomer) are added in vacuum emulsifying pot successively, then homogenizing makes raw material be uniformly dispersed (homogenizing speed is 2000-2500 rev/min, and the time is 5 minutes).Stirring is warming up to 80 DEG C (mixing speed is: 30-40 rev/min); Add triethanolamine to stir, 80 DEG C are incubated 25 minutes; Then being cooled to 55 DEG C of raw material sequence numbers that add is successively 8-16, and (mixing speed is: 30-40 rev/min) stirs; Being cooled to 45 DEG C, to add sequence number be 18,19,20,21 raw material, and (mixing speed is: 30-40 rev/min) stirs; Continue to be cooled to 40 DEG C, adding sequence number is that 22,23 raw material shifts to an earlier date pre-assigned microcapsule, stirs.
In embodiment 1-5, the weight content of each component is:
Embodiment 1:
Embodiment 2:
Embodiment 3:
Embodiment 4:
Embodiment 5:
comparative example 1-5: prepare common astringent:
The operating procedure of comparative example 1-5:
Under room temperature, deionized water, EDETATE SODIUM, allantoin, butanediol, glycerol, glycerol acrylate-acrylic copolymer and carbomer (from deionized water to carbomer) are added in vacuum emulsifying pot successively, then homogenizing makes raw material be uniformly dispersed (homogenizing speed is 2000-2500 rev/min, and the time is 5 minutes).Stirring is warming up to 80 DEG C (mixing speed is: 30-40 rev/min); Add triethanolamine to stir, 80 DEG C are incubated 25 minutes; Then being cooled to 55 DEG C of raw material sequence numbers that add is successively 8-14, and (mixing speed is: 30-40 rev/min) stirs; Being cooled to 45 DEG C, to add sequence number be 16,17,18,19 raw material, and (mixing speed is: 30-40 rev/min) stirs; Continue to be cooled to 40 DEG C, stir.
The composition weight percentage composition of comparative example 1-5 is:
Comparative example 1:
Comparative example 2:
Comparative example 3:
Comparative example 4:
Comparative example 5:
contrast test: the common astringent of the elite water of embodiment 1-5 and comparative example 1-5 is contrasted
Adopt SKIN-CT test, method is as follows:
1, experimenter requires: makeup removing, naturally dry facial skin after clean, and (about this process approximately 5 minutes), exposes whole face, avoids the impact of hair as far as possible.Wear dark upper garment, avoid the interference of light clothes; Environmental requirement: fixed area when test, under available light, 20-25 DEG C.
2, connect SKIN-CT and computer
3, obtain experimenter's face image: altogether obtain 3 groups of images, one group is the raw image data that after clean, skin dries naturally, and one group is the view data of smearing general embodiment product, and other one group is the view data of smearing elite water
4, instrument automatic analysis data carry out data statistics processing.
The model of SKIN-CT: LANACE 110, Shanghai Lanace Biotechnology Co., Ltd. produces.
According to the test result of SKIN-CT, the percent that the astringent moistening effect of comparative example 1-5 (moisture and skin beauty water are right) increases is respectively: 26.6%, 28.6%, 34.5%, 29.3% and 30.2%.The sophistication of skin increases by 15.2%, 15.8%, 16.7%, 15.5%, 17.1%, and wrinkle of skin reduces 8.7%, 8.9%, 9.3%, 9%, 9.6%, skin splash reduces 2.2%, 1.8%, 2.3%, 1.9%.2.5%, skin pore reduces 8.9%, 9.2%, and 9.5%, 8.8%, 9.0%;
The percent that the elite water moistening effect (moisture and skin beauty water are right) of embodiment 1-5 increases is respectively: 56.1%, 56.3%, 57.2%, 56.9% and 57%.The sophistication of skin increases by 32.3%, 32.4%, 33.6%, 32.6%, 33.1%, wrinkle of skin reduces 14.8%, 15%, 16.2%, 15.8%, 15.2%, skin splash reduces 6.0%, 5.9%, 6.6%, 6.0%, 6.5%, skin pore reduces 17.1%, 17.2%, 18.8%, 17.5%, 17.9%;
The elite water of embodiment 1-5 can increase by 56.7% product moistening effect after 14 days, and the sophistication of skin increases by 32.8%, and wrinkle of skin reduces 15.4%, and skin splash reduces 6.2%, and skin pore diminishes 17.7%.And the astringent of comparative example 1-5 on average can only increase by 29.84% moistening effect afterwards at 14 days, the sophistication of skin on average increases by 16.06%, and wrinkle of skin reduces 9.1%, skin splash decreased average 2.14%, and skin pore diminishes 9.08%.
Be below the source of component used in this detailed description of the invention:

Claims (3)

1. there is an elite water for slow-release function, the component that comprises following percentage by weight:
EDETATE SODIUM: 0.05%-0.1%; Essence: 0.01%-0.1%;
Allantoin: 0.1%-0.5%; Butanediol: 2%-6%;
Glycerol: 1%-8%; Glycerol acrylate-acrylic copolymer: 0.5%-3%;
Carbomer: 0.01%-0.15%; Herba Saussureae Involueratae extract: 1%-20%;
Caesalpinia spinosaKuntze extract: 1%-20%;
Aloe vulgaris leaf extract: 0.5%-8%;
Carbamide 10-25%, lactic acid 5-10%, pungent sweet sour 0.1-1%, hyaluronate sodium 0.1-1%, allantoin 0.1-1%, 1,2-hexanediol 0.1-1%, Anjidew NL50 5-10%, the mixture A:0.5%-2% that surplus is water;
Triethanolamine: 0.01%-0.15%; Diazolidinyl urea: 0.1%-0.6%;
Styrene And Chloroalkyl Acrylates and cinnamic acrylic ester analog copolymer: 0.01%-0.1%;
Lactose 20-35%, cellulose 35-50%, toner 0.1-5%, surplus is the mixture B:0.5%-3.0% of Caesalpinia spinosaKuntze extract;
Lactose 20-35%, cellulose 35-50%, the mixture C that surplus is Herba Saussureae Involueratae extract: 0.5%-3.0%;
Trehalose: 0.5%-3.0%; Hamamelis virginiana extract: 0.5%-6%;
Pantothenylol: 0.1%-1.0%; Flos Inulae extract: 0.5%-8%;
Beta glucan: 0.5%-5%; Castor oil hydrogenated: 0.1%-0.6%;
With surplus deionized water.
2. a method of preparing elite water described in claim 1, comprises the following steps:
A. prepare elite microcapsule: the preparation of Caesalpinia spinosaKuntze microcapsule: take cellulose by the amount of described mixture B, add 5 times of amount distilled water, in room temperature underlying colloid mill, and add Caesalpinia spinosaKuntze extract solution, the amount of the Caesalpinia spinosaKuntze extract solution adding is cellulosic 1/2nd, the weight concentration of solution is 5%, the mixing of fully milling, and machine intimate residual fraction repeatedly cleans on a small quantity with distilled water, be incorporated to washing liquid, the washing with alcohol that decompress filter is also 95% by purity 3 times, cold drying, obtains white powder; Then at room temperature by the amount of described mixture B, lactose, toner are joined in white powder, stir, speed is moderate, can not be too fast, and then the powder body of mix homogeneously is put into granulator and carry out pelletize, then gained granule is laid in a square position, spread evenly, put into drying baker and be dried, temperature is 35-40 DEG C, 24 hours time, place stand-by;
The preparation of Herba Saussureae Involueratae microcapsule: method is with the preparation method of Caesalpinia spinosaKuntze microcapsule, and Caesalpinia spinosaKuntze extract is being changed to Herba Saussureae Involueratae extract by difference, and add lactose and cellulose by the amount of mixture C;
B. the preparation of elite water: by the percentage by weight of described component, under room temperature, deionized water, EDETATE SODIUM, allantoin, butanediol, glycerol, glycerol acrylate-acrylic copolymer and carbomer are added in vacuum emulsifying pot successively, then homogenizing is uniformly dispersed raw material; Stirring is warming up to 80 DEG C; Add triethanolamine to stir, 80 DEG C are incubated 25 minutes; Then be cooled to 55 DEG C and add successively trehalose, Hamamelis virginiana extract, pantothenylol, Caesalpinia spinosaKuntze extract, Herba Saussureae Involueratae extract, Flos Inulae extract, Aloe vulgaris leaf extract, mixture A and beta glucan, stir; Be cooled to 45 DEG C and add diazolidinyl urea, Styrene And Chloroalkyl Acrylates and cinnamic acrylic ester analog copolymer, castor oil hydrogenated and essence, stir; Be cooled to 40 DEG C, slow down mixing speed, then add the microcapsule preparing in above-mentioned steps a, stir.
3. method according to claim 2, is characterized in that: described homogenizing speed is 2000-2500 rev/min, and the time is 5 minutes.
CN201210050789.2A 2012-02-29 2012-02-29 Essence lotion with slow release function and preparation method thereof Active CN103284895B (en)

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CN104382833B (en) * 2014-10-28 2015-11-18 广东碧嫄化妆品有限公司 Plant protein peptide stock solution and its preparation method and application
CN104434647B (en) * 2014-11-17 2017-05-03 上海应用技术学院 Nourishing and conditioning moisturizer containing highland barley beta-glucan and preparation method of moisturizer
CN106265101B (en) * 2016-09-05 2018-12-11 上海萧雅生物科技股份有限公司 Essence and preparation method thereof is sprayed with the micro-capsule for adjusting water and oil balance
CN108078902A (en) * 2018-02-01 2018-05-29 广州鹰远生物科技有限公司 A kind of essence lotion containing Flos persicae extract
CN114588091B (en) * 2022-04-21 2023-09-26 加来(济南)生活科技有限公司 Preparation method of cantaloupe fermentation primary pulp and application of cantaloupe fermentation primary pulp in cosmetics

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