CN103282474A - 从微生物生物质中获得包含多不饱和脂肪酸的组合物的方法 - Google Patents
从微生物生物质中获得包含多不饱和脂肪酸的组合物的方法 Download PDFInfo
- Publication number
- CN103282474A CN103282474A CN2011800202385A CN201180020238A CN103282474A CN 103282474 A CN103282474 A CN 103282474A CN 2011800202385 A CN2011800202385 A CN 2011800202385A CN 201180020238 A CN201180020238 A CN 201180020238A CN 103282474 A CN103282474 A CN 103282474A
- Authority
- CN
- China
- Prior art keywords
- microbial biomass
- biomass
- acid
- microbial
- oil
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
- C11B1/00—Production of fats or fatty oils from raw materials
- C11B1/10—Production of fats or fatty oils from raw materials by extracting
- C11B1/104—Production of fats or fatty oils from raw materials by extracting using super critical gases or vapours
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
- C11B7/00—Separation of mixtures of fats or fatty oils into their constituents, e.g. saturated oils from unsaturated oils
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Fats And Perfumes (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32679310P | 2010-04-22 | 2010-04-22 | |
| US61/326,793 | 2010-04-22 | ||
| PCT/US2011/033142 WO2011133610A1 (en) | 2010-04-22 | 2011-04-20 | Method for obtaining polyunsaturated fatty acid-containing compositions from microbial biomass |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103282474A true CN103282474A (zh) | 2013-09-04 |
Family
ID=44148979
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011800202385A Pending CN103282474A (zh) | 2010-04-22 | 2011-04-20 | 从微生物生物质中获得包含多不饱和脂肪酸的组合物的方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20110263709A1 (enExample) |
| EP (1) | EP2561050A1 (enExample) |
| JP (1) | JP2013525549A (enExample) |
| CN (1) | CN103282474A (enExample) |
| AU (1) | AU2011242843A1 (enExample) |
| CA (1) | CA2795460A1 (enExample) |
| CL (1) | CL2012002897A1 (enExample) |
| WO (1) | WO2011133610A1 (enExample) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109563527A (zh) * | 2016-07-13 | 2019-04-02 | 赢创德固赛有限公司 | 将脂质与裂解的含脂质生物质分开的方法 |
| CN113544244A (zh) * | 2019-03-14 | 2021-10-22 | 帝斯曼知识产权资产管理有限公司 | 通过酶和ph冲击从微生物细胞组合物中获得脂质的方法 |
| CN116254148A (zh) * | 2013-12-20 | 2023-06-13 | 帝斯曼知识产权资产管理有限公司 | 用于从微生物细胞获得微生物油的方法 |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2576801B1 (en) | 2010-06-01 | 2019-10-02 | DSM IP Assets B.V. | Extraction of lipid from cells and products therefrom |
| US20120213905A1 (en) * | 2010-08-11 | 2012-08-23 | E. I. Du Pont De Nemours And Company | Aquaculture feed compositions |
| JP6061866B2 (ja) | 2011-02-11 | 2017-01-18 | イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニーE.I.Du Pont De Nemours And Company | 微生物バイオマスから脂質含有組成物を得る方法 |
| JP2014510166A (ja) * | 2011-02-11 | 2014-04-24 | イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー | 短行程蒸留を使用する微生物源からのトリグリセリド油の精製 |
| CN105255738B (zh) * | 2011-07-21 | 2024-12-27 | 帝斯曼知识产权资产管理有限公司 | 生产二十碳五烯酸的微生物、脂肪酸组合物及其制作方法与用途 |
| SG11201403805WA (en) | 2012-01-06 | 2014-08-28 | Omthera Pharmaceuticals Inc | Dpa-enriched compositions of omega-3 polyunsaturated fatty acids in free acid form |
| AR095182A1 (es) | 2012-05-07 | 2015-09-30 | Omthera Pharmaceuticals Inc | Composiciones de estatinas y ácidos grasos omega-3 |
| FR2991337B1 (fr) * | 2012-05-29 | 2016-09-02 | Roquette Freres | Procede continu d'enrichissement en esters ethyliques de dha d'une huile produite par des microalgues |
| US10123986B2 (en) | 2012-12-24 | 2018-11-13 | Qualitas Health, Ltd. | Eicosapentaenoic acid (EPA) formulations |
| US9629820B2 (en) | 2012-12-24 | 2017-04-25 | Qualitas Health, Ltd. | Eicosapentaenoic acid (EPA) formulations |
| JP6824038B2 (ja) * | 2013-12-04 | 2021-02-03 | 日本水産株式会社 | ジホモ−γ−リノレン酸含有微生物油及びジホモ−γ−リノレン酸含有微生物菌体 |
| AU2014369042B2 (en) * | 2013-12-20 | 2020-04-30 | Dsm Ip Assets B.V. | Processes for obtaining microbial oil from microbial cells |
| BR112016014517B1 (pt) | 2013-12-20 | 2022-06-28 | Dsm Ip Assets B.V. | Processo para a obtenção de um óleo microbiano compreendendo um ou mais ácidos graxos poli-insaturados de uma ou mais células microbianas |
| JP2017500037A (ja) | 2013-12-20 | 2017-01-05 | ディーエスエム アイピー アセッツ ビー.ブイ. | 微生物細胞から微生物油を入手するための方法 |
| AR098893A1 (es) | 2013-12-20 | 2016-06-22 | Dsm Ip Assets Bv | Proceso para obtener aceite microbiano a partir de células microbianas |
| AU2022224053A1 (en) * | 2021-02-18 | 2023-09-14 | Cemvita Factory, Inc. | Systems and methods of making oil from microorganisms |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5539133A (en) * | 1992-06-12 | 1996-07-23 | Milupa Aktiengesellschaft | Process for extracting lipids with a high production of long-chain highly unsaturated fatty acids |
| CN1217029A (zh) * | 1996-03-28 | 1999-05-19 | 吉斯特-布罗卡迪斯股份有限公司 | 从用巴氏法灭菌的生物量中制备含有微生物多不饱和脂肪酸的油的方法 |
| WO2005047485A2 (en) * | 2003-11-12 | 2005-05-26 | E.I. Dupont De Nemours And Company | Delta12 desaturases suitable for altering levels of polyunsaturated fatty acids in oleaginous yeast |
| CN1662654A (zh) * | 2002-06-19 | 2005-08-31 | 帝斯曼知识产权资产管理有限公司 | 包含多不饱和脂肪酸的微生物油的制备 |
| CN1817846A (zh) * | 2005-02-08 | 2006-08-16 | 三得利株式会社 | 采用新型菌体处理方法制造多不饱和脂肪酸的方法 |
Family Cites Families (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4675132A (en) | 1985-03-28 | 1987-06-23 | The United States Of America As Represented By The Secretary Of Commerce | Polyunsaturated fatty acids from fish oils |
| US5169968A (en) * | 1985-09-10 | 1992-12-08 | Vitamins, Inc. | Mass separation of liquid or soluble components from solid materials utilizing supercritical fluids |
| ES2052564T3 (es) | 1986-07-08 | 1994-07-16 | Suntory Ltd | Procedimiento para la produccion de acido bishomo-gamma-linolenico y acido eicosapanteonico. |
| US5246841A (en) | 1986-12-26 | 1993-09-21 | Sagami Chemical Research Center | Microbial process for production of eicosapentaenoic acid |
| JP2582622B2 (ja) | 1987-10-27 | 1997-02-19 | 日東化学工業株式会社 | 糸状菌による高度不飽和脂肪酸の製造法 |
| US5340742A (en) | 1988-09-07 | 1994-08-23 | Omegatech Inc. | Process for growing thraustochytrium and schizochytrium using non-chloride salts to produce a microfloral biomass having omega-3-highly unsaturated fatty acids |
| US5244921A (en) | 1990-03-21 | 1993-09-14 | Martek Corporation | Eicosapentaenoic acids and methods for their production |
| US5658767A (en) | 1991-01-24 | 1997-08-19 | Martek Corporation | Arachidonic acid and methods for the production and use thereof |
| US5246842A (en) | 1991-10-30 | 1993-09-21 | The United States Of America As Represented By The Secretary Of Agriculture | Production of eicosapentaenoic acid from filamentous fungi utilizing lactose as a primary carbon source |
| JPH05308978A (ja) | 1992-05-11 | 1993-11-22 | Onoda Cement Co Ltd | 藻類によるドコサヘキサエン酸の製造方法 |
| AU5346296A (en) | 1995-04-17 | 1996-11-07 | Japan As Represented By Director-General Of Agency Of Industrial Science And Technology | Novel microorganisms capable of producing highly unsaturated fatty acids and process for producing highly unsaturated fa tty acids by using the microorganisms |
| US6255505B1 (en) | 1996-03-28 | 2001-07-03 | Gist-Brocades, B.V. | Microbial polyunsaturated fatty acid containing oil from pasteurised biomass |
| DK0935667T3 (da) | 1996-07-23 | 2007-04-10 | Nagase Chemtex Corp | Fremgangsmåde til fremstilling af docosahexaensyre og docosapentaensyre |
| US5968809A (en) | 1997-04-11 | 1999-10-19 | Abbot Laboratories | Methods and compositions for synthesis of long chain poly-unsaturated fatty acids |
| KR19990046733A (ko) | 1999-04-20 | 1999-07-05 | 류성구 | 미생물슈도모나스에의한도코사핵사노인산(dha)의제조방법 |
| GB2377455A (en) | 2001-02-09 | 2003-01-15 | Univ Hull | Method of culturing crypthecodinium cohnii |
| JP4280158B2 (ja) | 2002-12-27 | 2009-06-17 | 富士フイルム株式会社 | ドコサヘキサエン酸生産能を有する微生物及びその利用 |
| US7214491B2 (en) * | 2003-05-07 | 2007-05-08 | E. I. Du Pont De Nemours And Company | Δ-12 desaturase gene suitable for altering levels of polyunsaturated fatty acids in oleaginous yeasts |
| US8313911B2 (en) | 2003-05-07 | 2012-11-20 | E I Du Pont De Nemours And Company | Production of polyunsaturated fatty acids in oleaginous yeasts |
| US7238482B2 (en) | 2003-05-07 | 2007-07-03 | E. I. Du Pont De Nemours And Company | Production of polyunsaturated fatty acids in oleaginous yeasts |
| AU2005250074B2 (en) | 2004-06-04 | 2011-04-14 | Fluxome Sciences A/S | Metabolically engineered cells for the production of polyunsaturated fatty acids |
| US7550651B2 (en) | 2004-06-25 | 2009-06-23 | E.I. Du Pont De Nemours And Company | Delta-8 desaturase and its use in making polyunsaturated fatty acids |
| US7465564B2 (en) | 2004-08-10 | 2008-12-16 | E.I. Du Pont De Nemours And Company | Production of γ-linolenic acid in oleaginous yeast |
| US7879591B2 (en) | 2004-11-04 | 2011-02-01 | E.I. Du Pont De Nemours And Company | High eicosapentaenoic acid producing strains of Yarrowia lipolytica |
| US7550286B2 (en) | 2004-11-04 | 2009-06-23 | E. I. Du Pont De Nemours And Company | Docosahexaenoic acid producing strains of Yarrowia lipolytica |
| CN103589650A (zh) | 2005-03-18 | 2014-02-19 | 米克罗比亚公司 | 产油酵母和真菌中类胡萝卜素的产生 |
| US7470532B2 (en) | 2005-10-19 | 2008-12-30 | E.I. Du Pont De Nemours And Company | Mortierella alpina C16/18 fatty acid elongase |
| WO2007061742A1 (en) | 2005-11-23 | 2007-05-31 | E. I. Du Pont De Nemours And Company | Delta-9 elongases and their use in making polyunsaturated fatty acids |
| US7678560B2 (en) | 2006-05-17 | 2010-03-16 | E.I. Du Pont De Nemours And Company | Δ 5 desaturase and its use in making polyunsaturated fatty acids |
| US7695950B2 (en) | 2006-05-17 | 2010-04-13 | E. I. Du Pont De Nemours And Company | Δ5 desaturase and its use in making polyunsaturated fatty acids |
| WO2008054565A1 (en) | 2006-10-30 | 2008-05-08 | E. I. Du Pont De Nemours And Company | Δ17 desaturase and its use in making polyunsaturated fatty acids |
| US7709239B2 (en) | 2006-12-07 | 2010-05-04 | E.I. Du Pont De Nemours And Company | Mutant Δ8 desaturase genes engineered by targeted mutagenesis and their use in making polyunsaturated fatty acids |
| DK2129777T3 (en) | 2007-04-03 | 2016-01-25 | Du Pont | MULTIZYMER AND USE THEREOF FOR THE PRODUCTION OF polyunsaturated fatty acids |
| US8188338B2 (en) | 2007-04-10 | 2012-05-29 | E. I. Du Pont De Nemours And Company | Delta-8 desaturases and their use in making polyunsaturated fatty acids |
| US8119860B2 (en) | 2007-04-16 | 2012-02-21 | E. I. Du Pont De Nemours And Company | Delta-9 elongases and their use in making polyunsaturated fatty acids |
| US7943365B2 (en) | 2007-05-03 | 2011-05-17 | E.I. Du Pont De Nemours And Company | Δ-5 desaturases and their use in making polyunsaturated fatty acids |
| US8323935B2 (en) | 2007-10-03 | 2012-12-04 | E I Du Pont De Nemours And Company | Optimized strains of Yarrowia lipolytica for high eicosapentaenoic acid production |
| US8586104B2 (en) * | 2008-04-10 | 2013-11-19 | U.S. Nutraceuticals, LLC | Plant derived seed extract rich in essentially fatty acids derived from Salvia hispanica L. seed: composition of matter, manufacturing process and use |
| DK2324119T3 (en) | 2008-09-19 | 2016-07-18 | Du Pont | Mutant DELTA5 Desaturases AND USE THEREOF FOR THE PRODUCTION OF polyunsaturated fatty acids |
| CA2744716C (en) | 2008-12-18 | 2017-05-23 | E.I. Du Pont De Nemours And Company | Reducing byproduction of malonates in a fermentation process |
| US8399226B2 (en) | 2009-06-16 | 2013-03-19 | E I Du Pont De Nemours And Company | High eicosapentaenoic acid oils from improved optimized strains of Yarrowia lipolytica |
| JP6061866B2 (ja) * | 2011-02-11 | 2017-01-18 | イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニーE.I.Du Pont De Nemours And Company | 微生物バイオマスから脂質含有組成物を得る方法 |
-
2011
- 2011-04-20 CN CN2011800202385A patent/CN103282474A/zh active Pending
- 2011-04-20 CA CA2795460A patent/CA2795460A1/en not_active Abandoned
- 2011-04-20 WO PCT/US2011/033142 patent/WO2011133610A1/en not_active Ceased
- 2011-04-20 US US13/090,373 patent/US20110263709A1/en not_active Abandoned
- 2011-04-20 JP JP2013506252A patent/JP2013525549A/ja not_active Abandoned
- 2011-04-20 AU AU2011242843A patent/AU2011242843A1/en not_active Abandoned
- 2011-04-20 EP EP11718570A patent/EP2561050A1/en not_active Withdrawn
-
2012
- 2012-10-17 CL CL2012002897A patent/CL2012002897A1/es unknown
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5539133A (en) * | 1992-06-12 | 1996-07-23 | Milupa Aktiengesellschaft | Process for extracting lipids with a high production of long-chain highly unsaturated fatty acids |
| CN1217029A (zh) * | 1996-03-28 | 1999-05-19 | 吉斯特-布罗卡迪斯股份有限公司 | 从用巴氏法灭菌的生物量中制备含有微生物多不饱和脂肪酸的油的方法 |
| CN1662654A (zh) * | 2002-06-19 | 2005-08-31 | 帝斯曼知识产权资产管理有限公司 | 包含多不饱和脂肪酸的微生物油的制备 |
| WO2005047485A2 (en) * | 2003-11-12 | 2005-05-26 | E.I. Dupont De Nemours And Company | Delta12 desaturases suitable for altering levels of polyunsaturated fatty acids in oleaginous yeast |
| CN1817846A (zh) * | 2005-02-08 | 2006-08-16 | 三得利株式会社 | 采用新型菌体处理方法制造多不饱和脂肪酸的方法 |
Non-Patent Citations (3)
| Title |
|---|
| MILAN CERTIK,等: ""Supercritical CO2 extraction of fungal oil containing γ-linolenic acid", 《BIOTECHNOLOGY TECHNIQUES》 * |
| T.H. WALKER,等: "Supercritical Carbon Dioxide Extraction of Lipids from Pythium irregulare", 《JAOCS》 * |
| 李丽娜,等: "超临界CO2 萃取微生物油脂中ARA工艺条件的优化", 《中国粮油学报》 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116254148A (zh) * | 2013-12-20 | 2023-06-13 | 帝斯曼知识产权资产管理有限公司 | 用于从微生物细胞获得微生物油的方法 |
| CN109563527A (zh) * | 2016-07-13 | 2019-04-02 | 赢创德固赛有限公司 | 将脂质与裂解的含脂质生物质分开的方法 |
| CN113544244A (zh) * | 2019-03-14 | 2021-10-22 | 帝斯曼知识产权资产管理有限公司 | 通过酶和ph冲击从微生物细胞组合物中获得脂质的方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2561050A1 (en) | 2013-02-27 |
| JP2013525549A (ja) | 2013-06-20 |
| CL2012002897A1 (es) | 2014-04-11 |
| CA2795460A1 (en) | 2011-10-27 |
| US20110263709A1 (en) | 2011-10-27 |
| WO2011133610A1 (en) | 2011-10-27 |
| AU2011242843A1 (en) | 2012-09-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103282474A (zh) | 从微生物生物质中获得包含多不饱和脂肪酸的组合物的方法 | |
| US9040730B2 (en) | Purification of triglyceride oil from microbial sources using short path distillation | |
| US8999663B2 (en) | Method for obtaining a lipid-containing composition from microbial biomass | |
| US20130046020A1 (en) | Eicosapentaenoic acid concentrate | |
| EP0894142B2 (en) | Microbial oil containing a polyunsaturated fatty acid and method of producing oil from pasteurised and granulated biomass | |
| EP0904339B1 (en) | Sterol extraction with a polar solvent to give low sterol microbial oil | |
| US20130045226A1 (en) | Method for forming and extracting solid pellets comprising oil-containing microbes | |
| EP3786301A1 (en) | Microbial oil and method for producing microbial oil | |
| AU2012214266B2 (en) | Method for obtaining a lipid-containing composition from microbial biomass | |
| HK40088310A (en) | Microbial oil and method for producing microbial oil |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20130904 |