CN103274985A - 一种阿托伐他汀氨基酸盐 - Google Patents
一种阿托伐他汀氨基酸盐 Download PDFInfo
- Publication number
- CN103274985A CN103274985A CN2013102167334A CN201310216733A CN103274985A CN 103274985 A CN103274985 A CN 103274985A CN 2013102167334 A CN2013102167334 A CN 2013102167334A CN 201310216733 A CN201310216733 A CN 201310216733A CN 103274985 A CN103274985 A CN 103274985A
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- CN
- China
- Prior art keywords
- atorvastatin
- solution
- amino acid
- acid salts
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
Abstract
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Claims (4)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201310216733.4A CN103274985B (zh) | 2010-12-03 | 2011-11-14 | 一种阿托伐他汀氨基酸盐 |
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201010572658.1 | 2010-12-03 | ||
CN201010572658 | 2010-12-03 | ||
CN2010105726581 | 2010-12-03 | ||
CN 201110358863 CN102424663B (zh) | 2010-12-03 | 2011-11-14 | 一种阿托伐他汀氨基酸盐及其制备方法 |
CN201310216733.4A CN103274985B (zh) | 2010-12-03 | 2011-11-14 | 一种阿托伐他汀氨基酸盐 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN 201110358863 Division CN102424663B (zh) | 2010-12-03 | 2011-11-14 | 一种阿托伐他汀氨基酸盐及其制备方法 |
Publications (2)
Publication Number | Publication Date |
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CN103274985A true CN103274985A (zh) | 2013-09-04 |
CN103274985B CN103274985B (zh) | 2016-03-09 |
Family
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Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201310216732.XA Active CN103288702B (zh) | 2010-12-03 | 2011-11-14 | 一种阿托伐他汀氨基酸盐的制备方法 |
CN201310216733.4A Active CN103274985B (zh) | 2010-12-03 | 2011-11-14 | 一种阿托伐他汀氨基酸盐 |
CN 201110358863 Active CN102424663B (zh) | 2010-12-03 | 2011-11-14 | 一种阿托伐他汀氨基酸盐及其制备方法 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201310216732.XA Active CN103288702B (zh) | 2010-12-03 | 2011-11-14 | 一种阿托伐他汀氨基酸盐的制备方法 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
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CN 201110358863 Active CN102424663B (zh) | 2010-12-03 | 2011-11-14 | 一种阿托伐他汀氨基酸盐及其制备方法 |
Country Status (1)
Country | Link |
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CN (3) | CN103288702B (zh) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113321607A (zh) * | 2020-02-28 | 2021-08-31 | 北京福元医药股份有限公司沧州分公司 | 一种阿托伐他汀钙中间体的纯化方法 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6143755A (en) * | 1995-11-02 | 2000-11-07 | Warner-Lambert Company | Pharmaceutical methods of treatment with ACAT inhibitors and HMG-CoA reductase inhibitors |
CN1379760A (zh) * | 1999-10-18 | 2002-11-13 | 埃吉斯药物工厂 | 非晶形阿托伐他汀钙的制备方法 |
WO2003082816A1 (en) * | 2002-03-28 | 2003-10-09 | Richter Gedeon Vegyészeti Gyár Rt. | New atorvastatin salts and pharmaceutical compositions containing them |
WO2005105738A2 (en) * | 2004-05-05 | 2005-11-10 | Pfizer Products Inc. | Salt forms of atorvastatin |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HRP960313B1 (en) * | 1995-07-17 | 2002-08-31 | Warner Lambert Co | Form iii crystalline (r- (r*, r*)-2- (4-fluorophenyl) -beta-delta-hydroxy-5-(1-methylethyl) -3-phenyl-4- ((phenylamino) carbonyl -1h-pyrrole-1-heptanoic acid calcium salt (2:1) |
HU227041B1 (en) * | 2003-03-24 | 2010-05-28 | Richter Gedeon Nyrt | Process for the synthesis of amorphous atorvastatin calcium |
-
2011
- 2011-11-14 CN CN201310216732.XA patent/CN103288702B/zh active Active
- 2011-11-14 CN CN201310216733.4A patent/CN103274985B/zh active Active
- 2011-11-14 CN CN 201110358863 patent/CN102424663B/zh active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6143755A (en) * | 1995-11-02 | 2000-11-07 | Warner-Lambert Company | Pharmaceutical methods of treatment with ACAT inhibitors and HMG-CoA reductase inhibitors |
CN1379760A (zh) * | 1999-10-18 | 2002-11-13 | 埃吉斯药物工厂 | 非晶形阿托伐他汀钙的制备方法 |
WO2003082816A1 (en) * | 2002-03-28 | 2003-10-09 | Richter Gedeon Vegyészeti Gyár Rt. | New atorvastatin salts and pharmaceutical compositions containing them |
WO2005105738A2 (en) * | 2004-05-05 | 2005-11-10 | Pfizer Products Inc. | Salt forms of atorvastatin |
Also Published As
Publication number | Publication date |
---|---|
CN103274985B (zh) | 2016-03-09 |
CN102424663B (zh) | 2013-08-14 |
CN103288702B (zh) | 2015-09-16 |
CN103288702A (zh) | 2013-09-11 |
CN102424663A (zh) | 2012-04-25 |
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Legal Events
Date | Code | Title | Description |
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C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
ASS | Succession or assignment of patent right |
Owner name: SHANGHAI KEZHOU PHARMACEUTICAL RESEARCH + DEVELOPM Free format text: FORMER OWNER: BINJIANG PHARMA, INC. Effective date: 20140902 |
|
C41 | Transfer of patent application or patent right or utility model | ||
COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 300457 TANGGU, TIANJIN TO: 200051 CHANGNING, SHANGHAI |
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TA01 | Transfer of patent application right |
Effective date of registration: 20140902 Address after: 200051 Shanghai Zhangjiang hi tech Park Cailun Road, room 714 No. 780 Applicant after: KECHOW PHARMA, INC. Address before: 300457, N1601, sixteen floor, experimental building, Tianjin international biological medicine Joint Research Institute, No. 220 Dongting Road, Tanggu District, Tianjin Applicant before: Binjiang Pharma, Inc. |
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C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
C41 | Transfer of patent application or patent right or utility model | ||
TR01 | Transfer of patent right |
Effective date of registration: 20160422 Address after: Dongting Road Development Zone 300457 Tianjin Binhai New Area No. 220 Tianjin International Joint Research Institute of biomedical laboratory building seventeen floor N1701 Patentee after: Binjiang Pharma, Inc. Address before: 200051 Shanghai Zhangjiang hi tech Park Cailun Road, room 714 No. 780 Patentee before: KECHOW PHARMA, INC. |
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TR01 | Transfer of patent right | ||
TR01 | Transfer of patent right |
Effective date of registration: 20210226 Address after: 201203 block m, 3rd floor, 780 Cailun Road, Pudong New Area pilot Free Trade Zone, Shanghai Patentee after: KECHOW PHARMA, Inc. Address before: N1701, 17th floor, experimental building, Tianjin International Joint Research Institute of biomedicine, 220 Dongting Road, Binhai New Area Development Zone, Tianjin, 300457 Patentee before: TIANJIN BINJIANG PHARMACEUTICAL Inc. |