CN103261214B - 具有活细菌分离物的用于全身施用的疫苗 - Google Patents

具有活细菌分离物的用于全身施用的疫苗 Download PDF

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CN103261214B
CN103261214B CN201180061881.2A CN201180061881A CN103261214B CN 103261214 B CN103261214 B CN 103261214B CN 201180061881 A CN201180061881 A CN 201180061881A CN 103261214 B CN103261214 B CN 103261214B
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vaccine
bronchiseptica
canine
bordetella bronchiseptica
aroa
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Chinese (zh)
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CN103261214A (zh
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K.A.奥康内尔
R.拉夫勒尔
G.J.胡查帕
T.L.瓦斯莫恩
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Intervet International BV
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Intervet International BV
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/099—Bordetella
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/521—Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5252—Virus inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18711—Rubulavirus, e.g. mumps virus, parainfluenza 2,4
    • C12N2760/18734—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CN201180061881.2A 2010-12-22 2011-12-21 具有活细菌分离物的用于全身施用的疫苗 Active CN103261214B (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201061425855P 2010-12-22 2010-12-22
US61/425855 2010-12-22
EP11152829.5 2011-02-01
EP11152829 2011-02-01
US201161556975P 2011-11-08 2011-11-08
US61/556975 2011-11-08
PCT/IB2011/003100 WO2012085642A1 (en) 2010-12-22 2011-12-21 Vaccines with live bacterial isolates for systemic administration

Publications (2)

Publication Number Publication Date
CN103261214A CN103261214A (zh) 2013-08-21
CN103261214B true CN103261214B (zh) 2016-10-26

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US (1) US8821852B2 (enExample)
EP (1) EP2655403A1 (enExample)
JP (1) JP6145046B2 (enExample)
CN (1) CN103261214B (enExample)
BR (1) BR112013015009B1 (enExample)
CA (2) CA2821422C (enExample)
RU (1) RU2593953C2 (enExample)
WO (1) WO2012085642A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106729683B (zh) * 2016-12-16 2019-12-03 青岛易邦生物工程有限公司 一种猪支气管败血波氏杆菌病疫苗
CN113924111A (zh) * 2019-01-04 2022-01-11 勃林格殷格翰动物保健美国公司 减毒的支气管败血性博德特菌菌株、包含该减毒的菌株的口服疫苗及其制备和使用方法
CN114727904A (zh) * 2019-11-18 2022-07-08 礼蓝美国公司 在直壁小瓶中的冻干饼块
MX2022007578A (es) * 2019-12-18 2022-07-19 Intervet Int Bv Vacuna respiratoria oral.
EP3909971A1 (en) 2020-09-28 2021-11-17 Institute of Life Sciences (ILS) Whole cell livestock vaccine for respiratory diseases

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1246867A (zh) * 1996-10-11 2000-03-08 马普科技促进协会 幽门螺杆菌活疫苗
KR20080082883A (ko) * 2007-03-09 2008-09-12 전남대학교산학협력단 약독화된 보르데텔라 브론키셉티카 (ｂｂｓ) 균주 및 그의제조 방법, 그를 포함하는 면역원성 조성물 및 그를 이용한포유동물의 ｂｂｓ 감염증을 치료 또는 예방하는 방법

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8730037D0 (en) * 1987-12-23 1988-02-03 Wellcome Found Vaccines
US5955089A (en) * 1993-04-20 1999-09-21 Uab Research Foundation Strain selection of pneumococcal surface proteins
US5840556A (en) 1996-05-08 1998-11-24 The United States Of America As Represented By The Department Of Agriculture Molecular genetic construction of vaccine strains of pasteurellaceae
AUPR977601A0 (en) * 2001-12-28 2002-01-31 Delta Biotechnology Limited Defective entities and uses therefor
ES2303046T3 (es) * 2003-01-29 2008-08-01 Pfizer Products Inc. Vacunas caninas contra bordetella bronchiseptica.
US7959929B2 (en) 2005-04-21 2011-06-14 University Of Florida Research Foundation, Inc. Materials and methods for respiratory disease control in canines
WO2007042884A1 (en) * 2005-10-07 2007-04-19 Pfizer Products Inc. Vaccines and methods to treat canine influenza
WO2007104451A1 (en) 2006-03-10 2007-09-20 Institut Pasteur De Lille Live attenuated bordetella strains as a single dose vaccine against whooping cough
US20080254062A1 (en) 2007-02-23 2008-10-16 The Penn State Research Foundation Use of an avirulent bordetella mutant as a live vaccine vector
TWI468157B (zh) 2009-04-29 2015-01-11 Intervet Int Bv 形成錠劑的方法，進行該方法的系統及包含該錠劑的包裝物
CN101575586B (zh) * 2009-05-31 2011-01-19 华中农业大学 一种支气管败血波氏杆菌基因缺失疫苗及应用

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1246867A (zh) * 1996-10-11 2000-03-08 马普科技促进协会 幽门螺杆菌活疫苗
KR20080082883A (ko) * 2007-03-09 2008-09-12 전남대학교산학협력단 약독화된 보르데텔라 브론키셉티카 (ｂｂｓ) 균주 및 그의제조 방법, 그를 포함하는 면역원성 조성물 및 그를 이용한포유동물의 ｂｂｓ 감염증을 치료 또는 예방하는 방법

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
An aromatic amino acid auxothophic mutant of Bordetella bronchiseptica is attenuated and immunogenic in a mouse model of infection;Jason D Mcarthur et al;《FEMS microbiology letters》;20030430;第221卷(第1期);全文 *
减毒沙门氏菌作为DNA疫苗载体的研究进展;陈伟等;《生物技术通报》;20100228(第2期);全文 *

Also Published As

Publication number Publication date
WO2012085642A1 (en) 2012-06-28
US8821852B2 (en) 2014-09-02
CA2821422A1 (en) 2012-06-28
JP2014500302A (ja) 2014-01-09
CA3219727A1 (en) 2012-06-28
US20130273100A1 (en) 2013-10-17
RU2013133856A (ru) 2015-01-27
CA2821422C (en) 2024-01-02
EP2655403A1 (en) 2013-10-30
BR112013015009B1 (pt) 2020-11-10
BR112013015009A2 (pt) 2016-08-09
JP6145046B2 (ja) 2017-06-07
RU2593953C2 (ru) 2016-08-10
CN103261214A (zh) 2013-08-21

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