CA2821422C - Vaccines comprising live aro mutant bordetella bronchiseptica - Google Patents

Vaccines comprising live aro mutant bordetella bronchiseptica Download PDF

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Publication number
CA2821422C
CA2821422C CA2821422A CA2821422A CA2821422C CA 2821422 C CA2821422 C CA 2821422C CA 2821422 A CA2821422 A CA 2821422A CA 2821422 A CA2821422 A CA 2821422A CA 2821422 C CA2821422 C CA 2821422C
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CA
Canada
Prior art keywords
vaccine
bronchiseptica
canine
live
influenza virus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2821422A
Other languages
English (en)
French (fr)
Other versions
CA2821422A1 (en
Inventor
Kevin A. O'connell
Rhonda Lafleur
Huchappa Gowda Jayappa
Terri Lee Wasmoen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Intervet International BV
Original Assignee
Intervet International BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intervet International BV filed Critical Intervet International BV
Priority to CA3219727A priority Critical patent/CA3219727A1/en
Publication of CA2821422A1 publication Critical patent/CA2821422A1/en
Application granted granted Critical
Publication of CA2821422C publication Critical patent/CA2821422C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/099—Bordetella
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/521—Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5252—Virus inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18711—Rubulavirus, e.g. mumps virus, parainfluenza 2,4
    • C12N2760/18734—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CA2821422A 2010-12-22 2011-12-21 Vaccines comprising live aro mutant bordetella bronchiseptica Active CA2821422C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA3219727A CA3219727A1 (en) 2010-12-22 2011-12-21 Vaccines comprising live aro mutant bordetella bronchiseptica

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201061425855P 2010-12-22 2010-12-22
US61/425,855 2010-12-22
EP11152829 2011-02-01
EP11152829.5 2011-02-01
US201161556975P 2011-11-08 2011-11-08
US61/556,975 2011-11-08
PCT/IB2011/003100 WO2012085642A1 (en) 2010-12-22 2011-12-21 Vaccines with live bacterial isolates for systemic administration

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA3219727A Division CA3219727A1 (en) 2010-12-22 2011-12-21 Vaccines comprising live aro mutant bordetella bronchiseptica

Publications (2)

Publication Number Publication Date
CA2821422A1 CA2821422A1 (en) 2012-06-28
CA2821422C true CA2821422C (en) 2024-01-02

Family

ID=43628729

Family Applications (2)

Application Number Title Priority Date Filing Date
CA2821422A Active CA2821422C (en) 2010-12-22 2011-12-21 Vaccines comprising live aro mutant bordetella bronchiseptica
CA3219727A Pending CA3219727A1 (en) 2010-12-22 2011-12-21 Vaccines comprising live aro mutant bordetella bronchiseptica

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA3219727A Pending CA3219727A1 (en) 2010-12-22 2011-12-21 Vaccines comprising live aro mutant bordetella bronchiseptica

Country Status (8)

Country Link
US (1) US8821852B2 (enExample)
EP (1) EP2655403A1 (enExample)
JP (1) JP6145046B2 (enExample)
CN (1) CN103261214B (enExample)
BR (1) BR112013015009B1 (enExample)
CA (2) CA2821422C (enExample)
RU (1) RU2593953C2 (enExample)
WO (1) WO2012085642A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106729683B (zh) * 2016-12-16 2019-12-03 青岛易邦生物工程有限公司 一种猪支气管败血波氏杆菌病疫苗
EP3906049A1 (en) * 2019-01-04 2021-11-10 Boehringer Ingelheim Animal Health USA Inc. Attenuated bordetella bronchiseptica strains, oral vaccines containing the attenuated strains, and methods of making & use thereof
WO2021101720A1 (en) * 2019-11-18 2021-05-27 Elanco Us Inc. Lyophilized cake in straight-walled vial
JP2023506304A (ja) * 2019-12-18 2023-02-15 インターベット インターナショナル ベー． フェー． 経口呼吸器ワクチン
EP3909971A1 (en) 2020-09-28 2021-11-17 Institute of Life Sciences (ILS) Whole cell livestock vaccine for respiratory diseases

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8730037D0 (en) * 1987-12-23 1988-02-03 Wellcome Found Vaccines
US5955089A (en) * 1993-04-20 1999-09-21 Uab Research Foundation Strain selection of pneumococcal surface proteins
US5840556A (en) 1996-05-08 1998-11-24 The United States Of America As Represented By The Department Of Agriculture Molecular genetic construction of vaccine strains of pasteurellaceae
EP0835928A1 (en) * 1996-10-11 1998-04-15 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Berlin Helicobacter pylori live vaccine
AUPR977601A0 (en) * 2001-12-28 2002-01-31 Delta Biotechnology Limited Defective entities and uses therefor
AU2004208556B2 (en) * 2003-01-29 2009-06-04 Zoetis Services Llc Canine vaccines against bordetella bronchiseptica
US7959929B2 (en) 2005-04-21 2011-06-14 University Of Florida Research Foundation, Inc. Materials and methods for respiratory disease control in canines
PH12011502633A1 (en) * 2005-10-07 2012-11-12 Zoetis P Llc Vaccines and methods to treat canine influenza
EP3800244A1 (en) 2006-03-10 2021-04-07 Institut Pasteur de Lille Live attenuated bordetella strains as a single dose vaccine against whooping cough
EP2134359A4 (en) 2007-02-23 2010-06-16 Penn State Res Found USE OF A NONVIRULENT BORDETELLA MUTANT AS LIVING VACCINE VECTOR
KR20080082883A (ko) * 2007-03-09 2008-09-12 전남대학교산학협력단 약독화된 보르데텔라 브론키셉티카 (ｂｂｓ) 균주 및 그의제조 방법, 그를 포함하는 면역원성 조성물 및 그를 이용한포유동물의 ｂｂｓ 감염증을 치료 또는 예방하는 방법
TWI468157B (zh) 2009-04-29 2015-01-11 Intervet Int Bv 形成錠劑的方法，進行該方法的系統及包含該錠劑的包裝物
CN101575586B (zh) * 2009-05-31 2011-01-19 华中农业大学 一种支气管败血波氏杆菌基因缺失疫苗及应用

Also Published As

Publication number Publication date
US20130273100A1 (en) 2013-10-17
RU2593953C2 (ru) 2016-08-10
EP2655403A1 (en) 2013-10-30
BR112013015009A2 (pt) 2016-08-09
US8821852B2 (en) 2014-09-02
CA3219727A1 (en) 2012-06-28
RU2013133856A (ru) 2015-01-27
BR112013015009B1 (pt) 2020-11-10
CN103261214A (zh) 2013-08-21
JP6145046B2 (ja) 2017-06-07
JP2014500302A (ja) 2014-01-09
WO2012085642A1 (en) 2012-06-28
CN103261214B (zh) 2016-10-26
CA2821422A1 (en) 2012-06-28

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