CN103223086A - Traditional Chinese medicinal compound for controlling animal mycotoxin poisoning, and preparation method thereof - Google Patents
Traditional Chinese medicinal compound for controlling animal mycotoxin poisoning, and preparation method thereof Download PDFInfo
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- CN103223086A CN103223086A CN2013101664058A CN201310166405A CN103223086A CN 103223086 A CN103223086 A CN 103223086A CN 2013101664058 A CN2013101664058 A CN 2013101664058A CN 201310166405 A CN201310166405 A CN 201310166405A CN 103223086 A CN103223086 A CN 103223086A
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Abstract
The invention discloses a traditional Chinese medicinal compound for controlling animal mycotoxin poisoning. The traditional Chinese medicinal compound treats Phyllanthus urinaria L, Chinese Taxillus Twig, Himalayan Teasel Root, Herba Sedi, Chinese magnoliavine and Chinese yam as raw materials, and is obtained through primarily extracting the raw materials according to different characteristics of all the raw materials, uniformly mixing the obtained extract products of the raw materials in proportion, and carrying out vacuum drying to prepare a pulvis. The traditional Chinese medicinal compound has the advantages of unique and scientific formula and technology, and substantial treatment effect.
Description
Technical field
The present invention relates to the field of Chinese medicines for animals, be specifically related to a kind of Chinese medicine complex and preparation method that the poultry mycotoxin is poisoned of preventing and treating.
Background technology
Mycotoxin is common and dangerous fungal secondary metabolite, can pollute animal feed in each link of food chain.Mycete and mycotic spore are present in the soil usually, therefore very easy pollution feedstuff.Mycotoxin in the feedstuff be before results big field or results after produce under the holding conditions improperly.In recent years, the seriousness of the frequency of global feedstuff mycotoxin contamination and poultry mycotoxin poisoning increases year by year.Mycotoxin makes the fertility performance of animal descend usually, suppresses immune function, causes animal ill, and then enters in the human food chain health of harm humans by meat, milk and the internal organs of animal.
Poison for avoiding the poultry mycotoxin, can in animal and fowl fodder, add an amount of mold toxin sorbent, remove the mycotoxin in the feedstuff, but no matter the adsorbent effect of which kind of prescription all has self limitation, can not avoid the poultry mycotoxin to poison fully, and many adsorbents are because the selection of prescription, or defective workmanship, there is certain toxic and side effects, can causes certain injury the poultry body.Chinese herbal medicine is the employed unique medicine of prevention with Chinese medicine treatment disease, also is the important symbol that the traditional Chinese medical science is different from other medical science.The Chinese herbal medicine selection is from natural plants, through the science compatibility, rational processes, can strengthen its immunity and antibiotic property from poultry self, and have good detoxication and toxicant eliminating function effect, the culturist reinforces dual fail-safe for animal husbandry, reduces the murder by poisoning of mycotoxin to poultry, reduce loss, also can ensure the edible safety of consumer.
Summary of the invention
The object of the present invention is to provide a kind ofly to have poultry self the liver detoxification ability that strengthens, and can effectively prevent and treat the poultry mycotoxin and poison, alleviate the Chinese medicine complex of poultry poisoning symptom.
Another object of the present invention provides the preparation method of this Chinese medicine complex.
The technical scheme that realizes above-mentioned purpose is:
A kind of Chinese medicine complex of preventing and treating the poisoning of poultry mycotoxin is made by the following weight proportion raw material: Cacumen Securinegae Suffruticosae 10-25 part, Herba Taxilli 10-20 part, Radix Dipsaci 5-12 part, Herba Sedi 15-20 part, Fructus Schisandrae Chinensis 6-10 part, Rhizoma Dioscoreae 5-10 part;
The production method that above-mentioned each component is made Chinese medicine complex of the present invention is:
Herba Taxilli just extracts: get Herba Taxilli, add 10-15 times of mass fraction 80-90% of Herba Taxilli quality ethanol, in 65-80 ℃ of heating in water bath 2-3h, cross leaching filtrate, reclaim ethanol, get Herba Taxilli extract just;
Radix Dipsaci just extracts: get Radix Dipsaci and be crushed to 100 orders behind the 2-3h, add Radix Dipsaci quality 8-12 acetone backflow defat 1-2h doubly in 60 ℃ of oven dry, filter filtering residue, filtering residue adds 9-15 times of water gaging of filtering residue quality and decocts 2 times, each 1-2h, collecting decoction filters to such an extent that the first extracting solution of Radix Dipsaci is standby;
Rhizoma Dioscoreae is just extracted: get Rhizoma Dioscoreae and be crushed to 100 orders behind 50 ℃ of oven dry 3-5h, adding Rhizoma Dioscoreae quality 15-20 mass fraction doubly again is the ethanol of 80-90%, in 80-90 ℃ of reflux 2 times, each 2h, merge backflow,, get supernatant in the centrifugal 10-20min of 3000r/min, reclaim ethanol, just extract is standby to get Rhizoma Dioscoreae;
Cacumen Securinegae Suffruticosae, Herba Sedi, Fructus Schisandrae Chinensis powder are broken to 200 orders, each medical material after pulverizing and the first extract of Herba Taxilli, the first extracting solution of Radix Dipsaci, the first extract of Rhizoma Dioscoreae are mixed evenly, promptly through vacuum drying.
The effect of each component is as follows among the present invention:
Cacumen Securinegae Suffruticosae: mildly bitter flavor is sweet, and is cool in nature.Infringement has the effect of alleviating to its effective ingredient to hepatic pathology, and liver synthetic protein and glycogen generation are all had facilitation, can also improve the content of hepatocyte microsome cytochrome, thereby strengthen the function of detoxification of liver;
Fructus Schisandrae Chinensis: sour, sweet, temperature.Return lung, the heart, kidney channel.Has the astringing intestine to stop diarrhea of astringing the lung, the hidroschesis that promotes the production of body fluid, the function of reinforcing the kindey to control nocturnal emission.Also have the substance metabolism obstacle that alleviates toxic liver injury, have slight rising liver glycogen, alleviate hepatocellular degeneration, alleviate the poisoning virulence factor to liver cell mitochondria and lysosomal destruction, promote the synthetic effect of hepatocyte internal protein;
Herba Sedi: return liver, gallbladder, small intestine meridian.Has eliminating damp-heat, the antidotal function;
Herba Taxilli: bitter, sweet, flat.Return liver, kidney channel.Has wind-damp dispelling, invigorating the liver and kidney, the function of bone and muscle strengthening;
Rhizoma Dioscoreae: sweet, light, cold.Attach to the lung and stomach meridians.Has heat clearing away, the diuretic function;
Radix Dipsaci: bitter in the mouth; Hot; Slightly warm in nature.Return liver; Kidney channel.Promote the effect of tissue regeneration.
The mutual compatibility of each Chinese medicinal components, make product reach synergism from detoxifcation, toxin expelling and antitoxin each aspect, there are not other chemical raw materials, nontoxic to poultry, the effect that strengthens the antifungal toxin is arranged for normal poultry, have Detoxication for the calomel poisoning poultry, can alleviate poisoning symptom, and can unite use with other antidotes for the serious symptom poultry; The present invention need not decoct, and is easy to use, and controllability is strong.
Specific embodiment
The present invention is described further below in conjunction with specific embodiment, to help understanding content of the present invention.
Embodiment 1:
A kind of Chinese medicine complex of preventing and treating the poisoning of poultry mycotoxin is made by the following weight proportion raw material: 18 parts of Cacumen Securinegae Suffruticosaes, 16 parts of Herba Taxillis, 9 parts of Radix Dipsacis, 17 parts of Herba Sedis, 8 parts of Fructus Schisandrae Chinensis, 8 parts of Rhizoma Dioscoreaes;
The production method that above-mentioned each component is made Chinese medicine complex of the present invention is:
Herba Taxilli just extracts: get Herba Taxilli, add 13 times of mass fraction 85% ethanol of Herba Taxilli quality, in 70 ℃ of heating in water bath 2.5h, cross leaching filtrate, reclaim ethanol, get Herba Taxilli extract just;
Radix Dipsaci just extracts: get Radix Dipsaci and be crushed to 100 orders behind the 2.5h, add the acetone backflow defat 1.5h of 10 times of Radix Dipsaci quality in 60 ℃ of oven dry, filter filtering residue, filtering residue adds 12 times of water gagings of filtering residue quality and decocts 2 times, each 1.5h, collecting decoction filters to such an extent that the first extracting solution of Radix Dipsaci is standby;
Rhizoma Dioscoreae is just extracted: get Rhizoma Dioscoreae and be crushed to 100 orders in 50 ℃ of oven dry behind the 4h, the mass fraction that adds 17 times of Rhizoma Dioscoreae quality again is 85% ethanol, in 85 ℃ of reflux 2 times, each 2h merges backflow, in the centrifugal 15min of 3000r/min, get supernatant, reclaim ethanol, just extract is standby to get Rhizoma Dioscoreae;
Cacumen Securinegae Suffruticosae, Herba Sedi, Fructus Schisandrae Chinensis powder are broken to 200 orders, each medical material after pulverizing and the first extract of Herba Taxilli, the first extracting solution of Radix Dipsaci, the first extract of Rhizoma Dioscoreae are mixed evenly, promptly through vacuum drying.
Embodiment 2:
A kind of Chinese medicine complex of preventing and treating the poisoning of poultry mycotoxin is made by the following weight proportion raw material: 10 parts of Cacumen Securinegae Suffruticosaes, 10 parts of Herba Taxillis, 5 parts of Radix Dipsacis, 15 parts of Herba Sedis, 6 parts of Fructus Schisandrae Chinensis, 5 parts of Rhizoma Dioscoreaes;
The production method that above-mentioned each component is made Chinese medicine complex of the present invention is:
Herba Taxilli just extracts: get Herba Taxilli, add 10 times of mass fraction 80% ethanol of Herba Taxilli quality, in 65 ℃ of heating in water bath 2h, cross leaching filtrate, reclaim ethanol, get Herba Taxilli extract just;
Radix Dipsaci just extracts: get Radix Dipsaci and be crushed to 100 orders behind the 2h, add the acetone backflow defat 1h of 8 times of Radix Dipsaci quality in 60 ℃ of oven dry, filter filtering residue, filtering residue adds 9 times of water gagings of filtering residue quality and decocts 2 times, each 1h, collecting decoction, filter Radix Dipsaci just extracting solution is standby;
Rhizoma Dioscoreae is just extracted: get Rhizoma Dioscoreae and be crushed to 100 orders in 50 ℃ of oven dry behind the 3h, the mass fraction that adds 15 times of Rhizoma Dioscoreae quality again is 80% ethanol, in 80 ℃ of reflux 2 times, each 2h merges backflow, in the centrifugal 10min of 3000r/min, get supernatant, reclaim ethanol, just extract is standby to get Rhizoma Dioscoreae;
Cacumen Securinegae Suffruticosae, Herba Sedi, Fructus Schisandrae Chinensis powder are broken to 200 orders, each medical material after pulverizing and the first extract of Herba Taxilli, the first extracting solution of Radix Dipsaci, the first extract of Rhizoma Dioscoreae are mixed evenly, promptly through vacuum drying.
Embodiment 3:
A kind of Chinese medicine complex of preventing and treating the poisoning of poultry mycotoxin is made by the following weight proportion raw material: 25 parts of Cacumen Securinegae Suffruticosaes, 20 parts of Herba Taxillis, 12 parts of Radix Dipsacis, 20 parts of Herba Sedis, 10 parts of Fructus Schisandrae Chinensis, 10 parts of Rhizoma Dioscoreaes;
The production method that above-mentioned each component is made Chinese medicine complex of the present invention is:
Herba Taxilli just extracts: get Herba Taxilli, add 15 times of mass fraction 90% ethanol of Herba Taxilli quality, in 80 ℃ of heating in water bath 3h, cross leaching filtrate, reclaim ethanol, get Herba Taxilli extract just;
Radix Dipsaci just extracts: get Radix Dipsaci and be crushed to 100 orders behind the 3h, add the acetone backflow defat 2h of 12 times of Radix Dipsaci quality in 60 ℃ of oven dry, filter filtering residue, filtering residue adds 15 times of water gagings of filtering residue quality and decocts 2 times, each 2h, collecting decoction, filter Radix Dipsaci just extracting solution is standby;
Rhizoma Dioscoreae is just extracted: get Rhizoma Dioscoreae and be crushed to 100 orders in 50 ℃ of oven dry behind the 5h, the mass fraction that adds 20 times of Rhizoma Dioscoreae quality again is 90% ethanol, in 90 ℃ of reflux 2 times, each 2h merges backflow, in the centrifugal 20min of 3000r/min, get supernatant, reclaim ethanol, just extract is standby to get Rhizoma Dioscoreae;
Cacumen Securinegae Suffruticosae, Herba Sedi, Fructus Schisandrae Chinensis powder are broken to 200 orders, each medical material after pulverizing and the first extract of Herba Taxilli, the first extracting solution of Radix Dipsaci, the first extract of Rhizoma Dioscoreae are mixed evenly, promptly through vacuum drying.
Embodiment 4:
A kind of Chinese medicine complex of preventing and treating the poisoning of poultry mycotoxin is made by the following weight proportion raw material: 9 parts of Cacumen Securinegae Suffruticosaes, 8 parts of Herba Taxillis, 5 parts of Radix Dipsacis, 12 parts of Herba Sedis, 5 parts of Fructus Schisandrae Chinensis, 12 parts of Rhizoma Dioscoreaes;
All the other are with embodiment 1.
Embodiment 5:
A kind of Chinese medicine complex of preventing and treating the poisoning of poultry mycotoxin is made by the following weight proportion raw material: 28 parts of Cacumen Securinegae Suffruticosaes, 23 parts of Herba Taxillis, 15 parts of Radix Dipsacis, 22 parts of Herba Sedis, 12 parts of Fructus Schisandrae Chinensis, 12 parts of Rhizoma Dioscoreaes;
All the other are with embodiment 1.
Comparative Examples 1:
A kind of Chinese medicine complex of preventing and treating the poisoning of poultry mycotoxin is made by the following weight proportion raw material: 18 parts of Cacumen Securinegae Suffruticosaes, 9 parts of Radix Dipsacis, 17 parts of Herba Sedis, 8 parts of Fructus Schisandrae Chinensis, 8 parts of Rhizoma Dioscoreaes;
The production method that above-mentioned each component is made Chinese medicine complex of the present invention is:
Radix Dipsaci just extracts: get Radix Dipsaci and be crushed to 100 orders behind the 2.5h, add the acetone backflow defat 1.5h of 10 times of Radix Dipsaci quality in 60 ℃ of oven dry, filter filtering residue, filtering residue adds 12 times of water gagings of filtering residue quality and decocts 2 times, each 1.5h, collecting decoction filters to such an extent that the first extracting solution of Radix Dipsaci is standby;
Rhizoma Dioscoreae is just extracted: get Rhizoma Dioscoreae and be crushed to 100 orders in 50 ℃ of oven dry behind the 4h, the mass fraction that adds 17 times of Rhizoma Dioscoreae quality again is 85% ethanol, in 85 ℃ of reflux 2 times, each 2h merges backflow, in the centrifugal 15min of 3000r/min, get supernatant, reclaim ethanol, just extract is standby to get Rhizoma Dioscoreae;
Cacumen Securinegae Suffruticosae, Herba Sedi, Fructus Schisandrae Chinensis powder are broken to 200 orders, each medical material after pulverizing are mixed evenly with the first extracting solution of Radix Dipsaci, the first extract of Rhizoma Dioscoreae, promptly through vacuum drying.
Comparative Examples 2:
A kind of Chinese medicine complex of preventing and treating the poisoning of poultry mycotoxin is made by the following weight proportion raw material: 12 parts of Cacumen Securinegae Suffruticosaes, 14 parts of Herba Taxillis, 9 parts of Radix Dipsacis, 12 parts of Herba Sedis, 8 parts of Fructus Schisandrae Chinensis, 8 parts of Rhizoma Dioscoreaes, 6 parts in Poria, 7 parts of Rhizoma Atractylodis;
The production method that above-mentioned each component is made Chinese medicine complex of the present invention is:
Herba Taxilli just extracts: get Herba Taxilli, add 13 times of mass fraction 85% ethanol of Herba Taxilli quality, in 70 ℃ of heating in water bath 2.5h, cross leaching filtrate, reclaim ethanol, get Herba Taxilli extract just;
Radix Dipsaci just extracts: get Radix Dipsaci and be crushed to 100 orders behind the 2.5h, add the acetone backflow defat 1.5h of 10 times of Radix Dipsaci quality in 60 ℃ of oven dry, filter filtering residue, filtering residue adds 12 times of water gagings of filtering residue quality and decocts 2 times, each 1.5h, collecting decoction filters to such an extent that the first extracting solution of Radix Dipsaci is standby;
Rhizoma Dioscoreae is just extracted: get Rhizoma Dioscoreae and be crushed to 100 orders in 50 ℃ of oven dry behind the 4h, the mass fraction that adds 17 times of Rhizoma Dioscoreae quality again is 85% ethanol, in 85 ℃ of reflux 2 times, each 2h merges backflow, in the centrifugal 15min of 3000r/min, get supernatant, reclaim ethanol, just extract is standby to get Rhizoma Dioscoreae;
Cacumen Securinegae Suffruticosae, Herba Sedi, Fructus Schisandrae Chinensis, Poria, Rhizoma Atractylodis are crushed to 200 orders, each medical material after pulverizing and the first extract of Herba Taxilli, the first extracting solution of Radix Dipsaci, the first extract of Rhizoma Dioscoreae are mixed evenly, promptly through vacuum drying.
Comparative Examples 3:
A kind of Chinese medicine complex of preventing and treating the poisoning of poultry mycotoxin is made by the following weight proportion raw material: 18 parts of Cacumen Securinegae Suffruticosaes, 16 parts of Herba Taxillis, 9 parts of Radix Dipsacis, 17 parts of Herba Sedis, 8 parts of Fructus Schisandrae Chinensis, 8 parts of Rhizoma Dioscoreaes;
The production method that above-mentioned each component is made Chinese medicine complex of the present invention is:
Cacumen Securinegae Suffruticosae, Herba Taxilli, Radix Dipsaci, Herba Sedi, Fructus Schisandrae Chinensis, Rhizoma Dioscoreae powder are broken to 60 orders, with each the medical material mix homogeneously after pulverizing, promptly through vacuum drying.
The test example
Choose 200 of the healthy broiler in 1 age in week, be divided into 10 groups at random, 20 every group.Blank group feeding basal diet, the positive controls feeding daily ration that goes mouldy, other organize respectively the feeding daily ration that goes mouldy, and add the product of 3% embodiment 1-5, Comparative Examples 1-3 preparation respectively; Basal diet is made up of the prescription of following mass ratio: 65% corn, 15% bean cake, 4.6% fish flour, 5.4% cottonseed meal, 5% wheat bran, 3% premix material, 2% calcium hydrogen phosphate; The daily ration that goes mouldy is to come in the equivalent substitution basal diet corn gained with equal proportion by 10% the corn that goes mouldy.
Chicken health status, the behavior of searching for food are observed and write down to duration of test every day; 30 days experimental periods;
One, the Chinese medicine complex is to the influence of daily gain
Respectively test chicken is carried out live body when experimental period begins and finishes and weighs, the results are shown in Table 1:
Each test group test chicken daily gain situation of table 1
As seen from the above table: obviously there is influence in the daily ration that goes mouldy to the daily gain of test chicken, has added the Chinese medicine complex of the present invention's preparation, and test chicken daily gain situation makes moderate progress, wherein embodiment 1 effect optimum.Lacked Herba Taxilli simply in Comparative Examples 1 prescription, effect is obviously not as embodiment 1-5, many Poria and Rhizoma Atractylodis in the prescription of Comparative Examples 2, Comparative Examples 3 technologies are fairly simple, but effect not as embodiment 1-3, visible prescription of the present invention and technology are more scientific and reasonable.
Two, the mensuration of serum mesophytization enzymatic activity
After feeding experiment finished, the random choose test chicken was 8 from every group, and totally 80, freely drink water, to butcher behind the fasting 12h, after the depilation blood-letting, it is standby to get liver cold preservation, title carcass weight, record.
Blood serum sample: access blood sample with disposal plastic cup when butchering, in 37 ℃ of water-baths, leave standstill, treat after serum is separated out it to be sub-packed in the centrifuge tube, the centrifugal 1Omin of 3000rpm, get supernatant and be sub-packed in the eppendorf pipe, immerse liquid nitrogen immediately, put-30 ℃ of cryogenic refrigerators and preserve, adopt biochemistry analyzer to measure the activity of serum neutral and alkali phosphatase (AKP), glutamate pyruvate transaminase (GPT), glutamic oxaloacetic transaminase, GOT (GOT), the results are shown in Table 2:
The activity of serum mesophytization enzyme in each test group of table 2
As seen from the above table: the Chinese medicine complex of the present invention's preparation can improve the immunologic function of test chicken, compare with positive controls, embodiment 1-5 group enzymatic activity is all higher, embodiment 1 best results wherein, this with embodiment 1 in each component formulation ratio, technology and technological parameter rationally relevant.Comparative Examples 1-2 is different with Example formulations, Comparative Examples 3 technology differences, and effect is all not as embodiment 1-3.
Three, the mensuration of liver mesophytization enzymatic activity
Liver sample: get the about 20g in liver middle part of the test chicken after above-mentioned the butchering, in the plastic bag of packing into, preserve in the immersion liquid nitrogen postposition-30 ℃ cryogenic refrigerator.Adopt semi-automatic biochemical analyzer to measure in the hepatic homogenate liquid glutathion reductase (GR), glutathione S-transferase (GST), gland former times deaminase (ADA) activity.The results are shown in Table 3:
The preparation of 10% tissue homogenate: get about liver organization 0.5g, the cold saline of adding 0.86%, the volume total amount that makes normal saline is 9 times of a liver organization weight, be mixed with 10% hepatic homogenate liquid, composition grinds in 10ml homogenizer, make tissue homogenateization: the tissue homogenate for preparing is got supernatant and is carried out enzyme activity determination behind the centrifugal 10min of generic centrifuge 3000rpm.
The activity of each test group liver mesophytization enzyme of table 3
As seen from the above table: through the Chinese medicine complex of feeding the present invention preparation, test chicken liver mesophytization enzymatic activity all is significantly increased than positive controls, show that this complex can improve the test chicken liver function, wherein embodiment 1 best results, and Comparative Examples 1-3 effect is all not as embodiment 1.
Claims (5)
1. prevent and treat the Chinese medicine complex that the poultry mycotoxin is poisoned for one kind, it is characterized in that: it is the medicament of being made by following raw material: Cacumen Securinegae Suffruticosae, Herba Taxilli, Radix Dipsaci, Herba Sedi, Fructus Schisandrae Chinensis, Rhizoma Dioscoreae.
2. prevent and treat the Chinese medicine complex that the poultry mycotoxin is poisoned for one kind, it is characterized in that: it is the medicament of being made by the following weight proportion raw material: Cacumen Securinegae Suffruticosae 10-25 part, Herba Taxilli 10-20 part, Radix Dipsaci 5-12 part, Herba Sedi 15-20 part, Fructus Schisandrae Chinensis 6-10 part, Rhizoma Dioscoreae 5-10 part.
3. a kind of Chinese medicine complex that the poultry mycotoxin is poisoned of preventing and treating according to claim 2, it is characterized in that: wherein the weight proportion of each raw material is: 18 parts of Cacumen Securinegae Suffruticosaes, 16 parts of Herba Taxillis, 9 parts of Radix Dipsacis, 17 parts of Herba Sedis, 8 parts of Fructus Schisandrae Chinensis, 8 parts of Rhizoma Dioscoreaes.
4. a kind of Chinese medicine complex that the poultry mycotoxin is poisoned of preventing and treating according to claim 2, it is characterized in that: preparation method is:
Herba Taxilli just extracts: get Herba Taxilli, add 10-15 times of mass fraction 80-90% of Herba Taxilli quality ethanol, in 65-80 ℃ of heating in water bath 2-3h, cross leaching filtrate, reclaim ethanol, get Herba Taxilli extract just;
Radix Dipsaci just extracts: get Radix Dipsaci and be crushed to 100 orders behind the 2-3h, add Radix Dipsaci quality 8-12 acetone backflow defat 1-2h doubly in 60 ℃ of oven dry, filter filtering residue, filtering residue adds 9-15 times of water gaging of filtering residue quality and decocts 2 times, each 1-2h, collecting decoction filters to such an extent that the first extracting solution of Radix Dipsaci is standby;
Rhizoma Dioscoreae is just extracted: get Rhizoma Dioscoreae and be crushed to 100 orders behind 50 ℃ of oven dry 3-5h, adding Rhizoma Dioscoreae quality 15-20 mass fraction doubly again is the ethanol of 80-90%, in 80-90 ℃ of reflux 2 times, each 2h, merge backflow,, get supernatant in the centrifugal 10-20min of 3000r/min, reclaim ethanol, just extract is standby to get Rhizoma Dioscoreae;
Cacumen Securinegae Suffruticosae, Herba Sedi, Fructus Schisandrae Chinensis powder are broken to 200 orders, the mixing medical material after pulverizing and the first extract of Herba Taxilli, the first extracting solution of Radix Dipsaci, the first extract of Rhizoma Dioscoreae are mixed evenly, promptly through vacuum drying.
5. a kind of Chinese medicine complex that the poultry mycotoxin is poisoned of preventing and treating according to claim 3, it is characterized in that: preparation method is:
Herba Taxilli just extracts: get Herba Taxilli, add 13 times of mass fraction 85% ethanol of Herba Taxilli quality, in 70 ℃ of heating in water bath 2.5h, cross leaching filtrate, reclaim ethanol, get Herba Taxilli extract just;
Radix Dipsaci just extracts: get Radix Dipsaci and be crushed to 100 orders behind the 2.5h, add the acetone backflow defat 1.5h of 10 times of Radix Dipsaci quality in 60 ℃ of oven dry, filter filtering residue, filtering residue adds 12 times of water gagings of filtering residue quality and decocts 2 times, each 1.5h, collecting decoction filters to such an extent that the first extracting solution of Radix Dipsaci is standby;
Rhizoma Dioscoreae is just extracted: get Rhizoma Dioscoreae and be crushed to 100 orders in 50 ℃ of oven dry behind the 4h, the mass fraction that adds 17 times of Rhizoma Dioscoreae quality again is 85% ethanol, in 85 ℃ of reflux 2 times, each 2h merges backflow, in the centrifugal 15min of 3000r/min, get supernatant, reclaim ethanol, just extract is standby to get Rhizoma Dioscoreae;
Cacumen Securinegae Suffruticosae, Herba Sedi, Fructus Schisandrae Chinensis powder are broken to 200 orders, each medical material after pulverizing and the first extract of Herba Taxilli, the first extracting solution of Radix Dipsaci, the first extract of Rhizoma Dioscoreae are mixed evenly, promptly through vacuum drying.
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