CN103202786A - Traditional Chinese medicine composition extract with anti-dandruff function and application of same in cosmetic - Google Patents
Traditional Chinese medicine composition extract with anti-dandruff function and application of same in cosmetic Download PDFInfo
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- CN103202786A CN103202786A CN2012103773799A CN201210377379A CN103202786A CN 103202786 A CN103202786 A CN 103202786A CN 2012103773799 A CN2012103773799 A CN 2012103773799A CN 201210377379 A CN201210377379 A CN 201210377379A CN 103202786 A CN103202786 A CN 103202786A
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- 208000001840 Dandruff Diseases 0.000 title claims abstract description 46
- 239000000203 mixture Substances 0.000 title claims abstract description 40
- 239000003814 drug Substances 0.000 title claims abstract description 35
- 239000000284 extract Substances 0.000 title claims abstract description 34
- 239000002537 cosmetic Substances 0.000 title claims abstract description 11
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 41
- 239000007788 liquid Substances 0.000 claims abstract description 12
- 239000011347 resin Substances 0.000 claims abstract description 12
- 229920005989 resin Polymers 0.000 claims abstract description 12
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims abstract description 11
- 239000000706 filtrate Substances 0.000 claims abstract description 10
- 238000002360 preparation method Methods 0.000 claims abstract description 9
- 238000000605 extraction Methods 0.000 claims abstract description 8
- 238000010438 heat treatment Methods 0.000 claims abstract description 6
- 238000010992 reflux Methods 0.000 claims abstract description 6
- 239000002904 solvent Substances 0.000 claims abstract description 4
- 235000019441 ethanol Nutrition 0.000 claims description 22
- 230000006837 decompression Effects 0.000 claims description 10
- 238000010828 elution Methods 0.000 claims description 10
- 238000004064 recycling Methods 0.000 claims description 7
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical compound CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 claims description 6
- 239000003480 eluent Substances 0.000 claims description 5
- 239000012567 medical material Substances 0.000 claims description 5
- 230000000694 effects Effects 0.000 abstract description 9
- 239000000463 material Substances 0.000 abstract description 4
- 238000001914 filtration Methods 0.000 abstract description 2
- 238000000034 method Methods 0.000 abstract description 2
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 abstract 1
- 240000004510 Agastache rugosa Species 0.000 abstract 1
- 235000009051 Ambrosia paniculata var. peruviana Nutrition 0.000 abstract 1
- 235000003097 Artemisia absinthium Nutrition 0.000 abstract 1
- 240000001851 Artemisia dracunculus Species 0.000 abstract 1
- 235000017731 Artemisia dracunculus ssp. dracunculus Nutrition 0.000 abstract 1
- 235000003261 Artemisia vulgaris Nutrition 0.000 abstract 1
- 241000212948 Cnidium Species 0.000 abstract 1
- 241000717679 Mosla Species 0.000 abstract 1
- 240000002924 Platycladus orientalis Species 0.000 abstract 1
- 241001300193 Speranskia Species 0.000 abstract 1
- 239000001138 artemisia absinthium Substances 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 238000009833 condensation Methods 0.000 abstract 1
- 230000005494 condensation Effects 0.000 abstract 1
- 235000013399 edible fruits Nutrition 0.000 abstract 1
- 238000002156 mixing Methods 0.000 abstract 1
- 238000007873 sieving Methods 0.000 abstract 1
- 235000014347 soups Nutrition 0.000 abstract 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 abstract 1
- 238000012360 testing method Methods 0.000 description 9
- 241000555688 Malassezia furfur Species 0.000 description 8
- 241000233866 Fungi Species 0.000 description 5
- 239000000047 product Substances 0.000 description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- 230000000844 anti-bacterial effect Effects 0.000 description 4
- 230000003385 bacteriostatic effect Effects 0.000 description 4
- 239000003795 chemical substances by application Substances 0.000 description 4
- 239000002453 shampoo Substances 0.000 description 4
- 238000011282 treatment Methods 0.000 description 4
- 238000011161 development Methods 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 230000001408 fungistatic effect Effects 0.000 description 3
- 230000002401 inhibitory effect Effects 0.000 description 3
- 230000005764 inhibitory process Effects 0.000 description 3
- 210000002374 sebum Anatomy 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 238000003756 stirring Methods 0.000 description 3
- OWEGWHBOCFMBLP-UHFFFAOYSA-N 1-(4-chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethylbutan-2-one Chemical compound C1=CN=CN1C(C(=O)C(C)(C)C)OC1=CC=C(Cl)C=C1 OWEGWHBOCFMBLP-UHFFFAOYSA-N 0.000 description 2
- 208000003251 Pruritus Diseases 0.000 description 2
- 230000001476 alcoholic effect Effects 0.000 description 2
- 229940088710 antibiotic agent Drugs 0.000 description 2
- 230000001580 bacterial effect Effects 0.000 description 2
- 229960003344 climbazole Drugs 0.000 description 2
- 238000010790 dilution Methods 0.000 description 2
- 239000012895 dilution Substances 0.000 description 2
- 238000011156 evaluation Methods 0.000 description 2
- 239000000796 flavoring agent Substances 0.000 description 2
- 235000019634 flavors Nutrition 0.000 description 2
- 244000005700 microbiome Species 0.000 description 2
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- 230000028327 secretion Effects 0.000 description 2
- PICXIOQBANWBIZ-UHFFFAOYSA-N zinc;1-oxidopyridine-2-thione Chemical compound [Zn+2].[O-]N1C=CC=CC1=S.[O-]N1C=CC=CC1=S PICXIOQBANWBIZ-UHFFFAOYSA-N 0.000 description 2
- XMAYWYJOQHXEEK-OZXSUGGESA-N (2R,4S)-ketoconazole Chemical compound C1CN(C(=O)C)CCN1C(C=C1)=CC=C1OC[C@@H]1O[C@@](CN2C=NC=C2)(C=2C(=CC(Cl)=CC=2)Cl)OC1 XMAYWYJOQHXEEK-OZXSUGGESA-N 0.000 description 1
- LOEUPVXIWVJADW-UHFFFAOYSA-N 2-aminoethanol;1h-pyridin-2-one Chemical compound NCCO.O=C1C=CC=CN1 LOEUPVXIWVJADW-UHFFFAOYSA-N 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 208000035143 Bacterial infection Diseases 0.000 description 1
- 244000025254 Cannabis sativa Species 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- 208000007271 Substance Withdrawal Syndrome Diseases 0.000 description 1
- 208000022362 bacterial infectious disease Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000021403 epidermal cell division Effects 0.000 description 1
- IDGUHHHQCWSQLU-UHFFFAOYSA-N ethanol;hydrate Chemical compound O.CCO IDGUHHHQCWSQLU-UHFFFAOYSA-N 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 210000003128 head Anatomy 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 229960004125 ketoconazole Drugs 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 1
- 229950001046 piroctone Drugs 0.000 description 1
- BTSZTGGZJQFALU-UHFFFAOYSA-N piroctone olamine Chemical compound NCCO.CC(C)(C)CC(C)CC1=CC(C)=CC(=O)N1O BTSZTGGZJQFALU-UHFFFAOYSA-N 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 229960001141 pyrithione zinc Drugs 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 229960004889 salicylic acid Drugs 0.000 description 1
- 210000004761 scalp Anatomy 0.000 description 1
- 229940095673 shampoo product Drugs 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 229940043810 zinc pyrithione Drugs 0.000 description 1
Landscapes
- Cosmetics (AREA)
Abstract
The invention discloses a traditional Chinese medicine composition extract with an anti-dandruff function. The traditional Chinese medicine composition extract is characterized by comprising the following traditional Chinese medicine components by weight: 1 to 35% of wrinkled giant hyssop, 1 to 50% of speranskia herb, 1 to 40% of Chinese arborvitae twig and leaf, 1 to 35% of virgate wormwood herb, 1 to 30% of common cnidium fruit and 1 to 40% of Chinese mosla. A preparation method for the extract comprises the following steps: crushing a composition of the above-mentioned traditional Chinese medicine components; carrying out sieving at first and uniform mixing next; adding an extraction solvent and carrying out heating for reflux extraction once to three times; combining obtained liquid extracts together; subjecting a filtrate to pressure reduction condensation until the filtrate is 100 mL; rinsing the filtrate on a macroporous resin column with a resin model of D101 or AB-8 until the filtrate is colorless; eluting the filtrate with ethanol having a concentration of 20 to 80% until eluates are colorless and respectively collecting the ethanol eluates; recovering ethanol at a temperature of 50 to 80 DEG C under the condition of reduced pressure until a ratio of a soup to medicinal materials is 1:2 to 1: 10; adding butylene glycol with a concentration of 10 to 60% for dissolving; and carrying out decoloring with active carbon and filtration so as to prepare the traditional Chinese medicine composition extract. The traditional Chinese medicine composition extract prepared by using the method has bacteriostasis and anti-dandruff functions and presents bacteriostasis and anti-dandruff effects when used in an anti-dandruff cosmetic.
Description
Technical field
The present invention relates to a kind of composite Chinese medicine composition, said composition has the anti-dandruff function, can be applied to remove the shampoo product of the dandruff.
Background technology
Along with making rapid progress of science and technology, progressively sectionalization and the variation of development of anti-dandruff product on the current market.How using anti-dandruff product and having better anti-dandruff effect is the important topic that the cosmetology field is inquired into.In the dandruff medically and not serious, but from the cosmetology angle, often bring a lot of worries to people.Discover that the adult Chinese 60% is subjected to the dandruff puzzlement to some extent, the dandruff problem is more more general than American-European countries.This mainly is because Chinese Consumer's is not noted skin of head health care, bad hygienic habit and selected for use the uncomfortable hair products of washing to cause.
The reason that the dandruff produces mainly contains two aspects: the one, and microorganism (as fungus and antibacterials such as Malassezia furfurs) is infected and is caused the hypodermal cell division to be accelerated; The 2nd, sebum secretion is too vigorous, and sebum is attached on the scalp with the cell that comes off, and just becomes the dandruff in small, broken bits after the drying.So anti-dandruff the best way suppresses microbial growth exactly and suppresses sebum secretion.
Anti-dandruff dose that present anti-dandruff dose of product is commonly used has salicylic acid, pyrithione zinc (ZPT), ketoconazole, climbazole (climbazole) and pyridone ethanolamine (Octopirox) etc., and these dandruff removing agents mainly reach the anti-dandruff purpose by suppressing microorganism.These dandruff removing agents are the material of chemosynthesis, and are bigger to the zest of human body, are cosmetics and limit the use of material.Development along with society, the raising of people's living standard, also more and more higher to the cosmetics safety requirement, particularly many safety issues have appearred in cosmetic industry in recent years, impel people more and more higher to green, safe, healthy cry, thereby advanced the Application and Development of natural dandruff removing agent.The present invention then adopts the Chinese medicine composition low to the human body zest, that toxicity is low as fungus and bacterial inhibitors such as Malassezia furfurs, reaches the purpose of anti-dandruff.
Summary of the invention
The objective of the invention is in order to overcome the defective of chemosynthesis dandruff removing agent, providing a kind of is that having of being prepared from of primary raw material is antibacterial with the natural Chinese medicinal herb, the medium-height grass compositions extract of anti-dandruff effect, this Chinese medicine composition component is reasonable, Synergistic, its extract can suppress fungus and antibacterials such as Malassezia furfur, has the function of anti-dandruff.
To achieve the object of the present invention, the present invention has adopted following technical scheme:
A kind of Chinese medicine composition with anti-dandruff function is characterized in that comprising the Chinese medicinal components of following percentage by weight:
Herba Pogostemonis 1-35%;
Herba speranskiae tuberculatae 1-50%;
Cacumen Platycladi 1-40%;
Herba Artemisiae Scopariae 1-35%;
Fructus Cnidii 1-30%;
Herba Moslae 1-40%.
For obtaining above-mentioned Chinese medicine composition extract, the present invention has adopted following manufacture method: with Herba Pogostemonis, Herba speranskiae tuberculatae, Cacumen Platycladi, Herba Artemisiae Scopariae, Fructus Cnidii, Herba Moslae is pulverized, the back mix homogeneously sieves, add and extract solvent, heating and refluxing extraction 1-3 time, merge extractive liquid,, filtrate decompression is concentrated into 100ml, the macroporous resin column that goes up the resin model again and be D101 or AB-8 be washed to colourless after, use the 20%-80% ethanol elution colourless to eluent again, and collect ethanol elution respectively, be 1: 2～1: 10 in 50 ℃ of-80 ℃ of decompression recycling ethanols to medicinal liquid with the medical material ratio again, add the dissolving of 10%-60% butanediol, use activated carbon decolorizing, filter, make Chinese medicine active site extract.The extraction solvent that uses among the present invention can adopt water, ethanol, ethanol water.
Second purpose of the present invention is that above-mentioned Chinese medicine composition extract is used for anti-dandruff product, makes stable in properties, respond well anti-dandruff cosmetics.
For realizing second purpose of the present invention, the present invention has adopted following technical scheme: above-mentioned Chinese medicine composition extract is used for the anti-dandruff cosmetics of preparation, it is characterized in that containing in the anti-dandruff cosmetics above-mentioned Chinese medicine composition extract, its consumption is 0.1-25%, and preferable amount is 1-10%.
Beneficial effect of the present invention: Chinese medicine composition extract of the present invention has very strong fungus and bacterial actions such as inhibition Malassezia furfur, has the dandruff of removal function.
The specific embodiment
Below come by specific embodiment that the present invention is further illustrated, but these embodiment are not limitations of the present invention just in order to illustrate.
The preparation of embodiment 1 Chinese medicine composition extract (I)
Get Herba Pogostemonis, Herba speranskiae tuberculatae, Cacumen Platycladi, Herba Artemisiae Scopariae, Fructus Cnidii, each 10g of Herba Moslae, pulverize, cross mix homogeneously behind 60 mesh sieves, add pure water 1.2kg, heating and refluxing extraction 60min, repeat to extract 2 times, merge extractive liquid, is concentrated into 100m1 with filtrate decompression, the macroporous resin column that goes up the resin model again and be D101 or AB-8 be washed to colourless after, use 20% ethanol elution colourless to eluent again, and collect ethanol elution respectively, and be 1: 5 in 60 ℃ of decompression recycling ethanols to medicinal liquid with the medical material ratio again, add the dissolving of 10% butanediol, with activated carbon decolorizing, filtration, namely.
The preparation of embodiment 2 Chinese medicine composition extracts (II)
Get Herba Pogostemonis 5g, Herba speranskiae tuberculatae 5g, Cacumen Platycladi 10g, Herba Artemisiae Scopariae 15g, Fructus Cnidii 15g, Herba Moslae 10g, pulverize, cross mix homogeneously behind 60 mesh sieves, add 30% ethanol 1.2kg, heating and refluxing extraction 60min, repeat to extract 2 times, merge extractive liquid,, with filtrate in 60 ℃ of decompression recycling ethanols after do not have the alcohol flavor, add 2 times of water gaging dilutions, the macroporous resin column that goes up the resin model again and be D101 or AB-8 be washed to colourless after, use 40% ethanol elution colourless to eluent again, and collect ethanol elution, be 1: 6 in 60 ℃ of decompression recycling ethanols to medicinal liquid with the medical material ratio again, add the dissolving of 30% butanediol, use activated carbon decolorizing, filter, namely.
The preparation of embodiment 3 Chinese medicine composition extracts (III)
Get Herba Pogostemonis 5g, Herba speranskiae tuberculatae 5g, Cacumen Platycladi 5g, Herba Artemisiae Scopariae 20g, Fructus Cnidii 20g, Herba Moslae 5g, pulverize, cross mix homogeneously behind 60 mesh sieves, add 70% ethanol 1.2kg, heating and refluxing extraction 60min, repeat to extract 2 times, merge extractive liquid,, with filtrate in 65 ℃ of decompression recycling ethanols after do not have the alcohol flavor, add 2 times of water gaging dilutions, the macroporous resin column that goes up the resin model again and be D101 or AB-8 be washed to colourless after, use 70% ethanol elution colourless to eluent again, and collect ethanol elution, be 1: 6 in 65 ℃ of decompression recycling ethanols to medicinal liquid with the medical material ratio again, add the dissolving of 50% butanediol, use activated carbon decolorizing, filter, namely.
The research of embodiment 4 fungistatic effects
By the Chinese medicine composition extract that above-described embodiment 3 makes, numbering A has carried out hair (skin) is easily grown, and the bacteriostatic test of bacterial infection and fungus is tested as follows:
1. test specimen
Totally 4 groups, number as follows
A Chinese medicine composition extract
B 50% butanediol
C ZPT Zinc Pyrithione
2. test index
Inhibition zone diameter (mm); Minimal inhibitory concentration (MIC, %)
3. result of the test
3.1 broad spectrum activity bacteriostatic test result
Table 1 broad spectrum activity bacteriostatic test result
According to experimental result as can be known, the strain subject of A, C is comparatively responsive, contrast ZPT (ZPT concentration was at 0.4% o'clock, and the inhibition zone diameter maximum increases the ZPT consumption again, and antibacterial ring increases not obvious), and the Chinese medicine composition extract can reach good fungistatic effect.
3.2. feature bacterium bacteriostatic test result
Table 2 minimum inhibitory concentration (MIC)
| The sample title | Strain subject | Minimum inhibitory concentration (MIC) |
| A | Malassezia furfur | 0.05％ |
| B | Malassezia furfur | 20％ |
| C | Malassezia furfur | 0.005％ |
Annotate: Malassezia furfur liquid concentration is 4 * 10
5Cfu/m1.
According to test data as can be known, this Chinese medicine composition extract can reach the fungistatic effect of ZPT substantially.
Embodiment 5 anti-dandruff effect assessment tests
Embodiment 3 preparation Chinese medicine composition extracts are dissolved in 10% alcoholic solution, are made into 1% Chinese medicine composition extract solution, as specimen; With 10% alcoholic solution as blank.
Select 25-45 year dandruff patient 80 people, be divided into 2 groups, wherein every group of male 20 people, women 20 people, crowd on probation.
Therapeutic Method: the patient will try out sample and embrocate the affected part gently with absorbent cotton, kowtow gently at the coating place with finger and hit 2min, and morning every day, 7 was a course for the treatment of, treats 2 courses for the treatment of continuously with 1 time.Follow up a case by regular visits to record result, drug withdrawal post-evaluation curative effect before and after all patient treatments.
Curative effect determinate standard: recovery from illness (dandruff disappears, no scratchiness); Effectively (dandruff reduces, and pruritus disappears); Invalid (dandruff slightly reduces or no change, and pruritus is slightly clear or the same).Efficacy result is shown in Table 3.
Table 3 therapeutic evaluation result
Table 3 is the result show, Chinese medicine composition extract of the present invention has very obvious effects to the treatment dandruff, and effectively above ratio reaches 95%.
Embodiment 6 soft and moist anti-dandruff shampoos and preparation method thereof
Table 4 provides the soft and moist anti-dandruff shampoo prescription that contains the Chinese medicine composition extract, and the consumption of each material is represented with mass fraction.
The soft and moist anti-dandruff shampoo prescription of table 4
The described anti-dandruff shampoo step of this implementation column preparation technology:
1, the powder among the A is added to the water while stirring; Be stirred and heated to 80 ℃ of dissolvings fully;
2, add B successively, be stirred to table dissolving fully alive;
3, while stirring the C item is added system successively, be stirred to dissolving and cool to room temperature fully;
4, add D successively, stir;
5, adjust viscosity with salt at last, approximately always proper with salt amount 1.0 left and right sides.
Claims (2)
1. Chinese medicine composition extract with anti-dandruff function is characterized in that comprising the Chinese medicinal components of following percentage by weight: Herba Pogostemonis 1-35; Herba speranskiae tuberculatae 1-50; Cacumen Platycladi 1-40; Herba Artemisiae Scopariae 1-35; Fructus Cnidii 1-30; Herba Moslae 1-40.The Chinese medicine composition preparation method of extract is that Chinese medicine composition is pulverized, the back mix homogeneously sieves, add and extract solvent, heating and refluxing extraction 1-3 time, merge extractive liquid,, filtrate decompression is concentrated into 100mL, the macroporous resin column that goes up the resin model again and be D101 or AB-8 be washed to colourless after, use the 20%-80% ethanol elution colourless to eluent again, and collect ethanol elution respectively, and be 1: 2～1: 10 in 50 ℃ of-80 ℃ of decompression recycling ethanols to medicinal liquid with the medical material ratio again, add the dissolving of 10%-60% butanediol, use activated carbon decolorizing, filter, make the Chinese medicine composition extract.
2. the anti-dandruff cosmetics that contain the Chinese medicine composition extract of claim 1 is characterized in that containing in the anti-dandruff cosmetics the described Chinese medicine composition extract of claim 1, and its consumption is 0.1-25%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210377379.9A CN103202786B (en) | 2012-09-29 | 2012-09-29 | Traditional Chinese medicine composition extract with anti-dandruff function and application of same in cosmetic |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210377379.9A CN103202786B (en) | 2012-09-29 | 2012-09-29 | Traditional Chinese medicine composition extract with anti-dandruff function and application of same in cosmetic |
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| Publication Number | Publication Date |
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| CN103202786A true CN103202786A (en) | 2013-07-17 |
| CN103202786B CN103202786B (en) | 2014-12-10 |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103961291A (en) * | 2014-05-30 | 2014-08-06 | 广州丹奇日用化工厂有限公司 | Elsholtzia ciliata hyland extract, preparation method and application thereof |
| CN109464317A (en) * | 2018-12-14 | 2019-03-15 | 上海辉文生物技术股份有限公司 | A kind of composition and its preparation method and application containing Thuja extract |
| CN112006957A (en) * | 2020-09-08 | 2020-12-01 | 赣州佰珍堂生物科技有限公司 | Extraction process of effective components of cosmetic extracting solution |
| CN112274469A (en) * | 2020-11-10 | 2021-01-29 | 广州环亚化妆品科技有限公司 | Traditional Chinese medicine composition and application thereof |
| CN115414301A (en) * | 2022-10-21 | 2022-12-02 | 广州德谷个人护理用品有限公司 | Plant anti-dandruff composition and preparation method and application thereof |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103961291A (en) * | 2014-05-30 | 2014-08-06 | 广州丹奇日用化工厂有限公司 | Elsholtzia ciliata hyland extract, preparation method and application thereof |
| CN109464317A (en) * | 2018-12-14 | 2019-03-15 | 上海辉文生物技术股份有限公司 | A kind of composition and its preparation method and application containing Thuja extract |
| CN112006957A (en) * | 2020-09-08 | 2020-12-01 | 赣州佰珍堂生物科技有限公司 | Extraction process of effective components of cosmetic extracting solution |
| CN112274469A (en) * | 2020-11-10 | 2021-01-29 | 广州环亚化妆品科技有限公司 | Traditional Chinese medicine composition and application thereof |
| CN115414301A (en) * | 2022-10-21 | 2022-12-02 | 广州德谷个人护理用品有限公司 | Plant anti-dandruff composition and preparation method and application thereof |
| CN115414301B (en) * | 2022-10-21 | 2024-02-27 | 广州德谷个人护理用品有限公司 | Plant anti-dandruff composition and preparation method and application thereof |
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| CN103202786B (en) | 2014-12-10 |
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Address after: 510663 No. 15, Colin Road, Guangzhou Science City, Guangzhou high tech Industrial Development Zone, Guangdong Province Patentee after: Guangzhou Huanya cosmetics technology Co.,Ltd. Address before: 510663 Guangzhou High-tech Industrial Development Zone, Guangzhou, Guangdong Province, 15 Kelin Road, Guangzhou Science City Patentee before: GUANGZHOU HUANYA COSMETICS TECHNOLOGY Co.,Ltd. |
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Application publication date: 20130717 Assignee: Guangzhou Novi Biotechnology Co.,Ltd. Assignor: Guangzhou Huanya cosmetics technology Co.,Ltd. Contract record no.: X2024980013201 Denomination of invention: A traditional Chinese medicine compound extract with dandruff removing function and its application in cosmetics Granted publication date: 20141210 License type: Common License Record date: 20240828 |
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