CN103751613A - Traditional Chinese medicinal liniment for treating seborrhoeic dermatitis due to wind heat and blood dryness - Google Patents
Traditional Chinese medicinal liniment for treating seborrhoeic dermatitis due to wind heat and blood dryness Download PDFInfo
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- CN103751613A CN103751613A CN201410020766.6A CN201410020766A CN103751613A CN 103751613 A CN103751613 A CN 103751613A CN 201410020766 A CN201410020766 A CN 201410020766A CN 103751613 A CN103751613 A CN 103751613A
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Abstract
The invention discloses a traditional Chinese medicinal liniment for treating seborrhoeic dermatitis due to wind heat and blood dryness. Seborrhoeic dermatitis belongs to the fields of seborrhea sicca and seborrheic eczema in traditional Chinese medicine. Seborrhoeic dermatitis due to wind heat and blood dryness is caused by blood dryness, wind heat, skin dystrophy, wind pathogen, and hematozemia. Traditional Chinese medicinal materials including Herba Ainsliaeae Fragrantis, Gentiana rhodantha, Odontites serotina, Dracocephalum rupestre, Apium graveolens, Panicum repens, Artemisia rupetris, Mosla caualeriei and Daucus carota are selected to be made into liniment. According to clinical trials, the total effective rate is up to 97.7%, which is significantly higher than the total effective rate (83.7%) of a control group.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of Chinese medicinal liniment for the treatment of wind heat blood-dryness type seborrheic dermatitis.
Background technology
Seborrheic dermatitis claims again seborrheic eczema, is to occur in sebaceous gland to enrich the chronic pimple squama of the one inflammatory skin disease at position.Primary disease is more common in adult and neonate, is apt to occur in the sebaceous gland such as women's head-ornaments, trunk and enriches district.Its cause of disease pathogeny it be unclear that, and thinks at present and paraplasm and the infection of the microorganism such as local fungal, staphylococcus aureus, and patient immune function's is abnormal, the shortage of trace element zinc, androgen raises, and sebum secretion is vigorous, heredodiathesiies etc. are relevant, psychentonia in addition, dietary habit, vitamin B complex lacks, ring mirror factor, the many factors such as congenital skin barrier function obstacle can bring out and increase the weight of primary disease, are easy to clinically diagnosis, after treatment, can control the state of an illness, but tend to recurrence.Western medical treatment generally adopts the method treatments such as sebum steroid and antifungal, androgen antagonist, antiinflammatory, but relapse rate is high, and drug kinds is few, and price is more expensive, and side effect is large.Clinical practice for many years proves, external treatment of Chinese medicine is simple to operate, and easy honest and clean effect is easy to use, low price, and curative effect is reliable.External treatment of Chinese medicine, by medicine or treatment operation, directly acts on diseased region, rapid-action, plays a role fully, and local efficacy is better than treatment by oral administration of medicines.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicinal liniment for the treatment of wind heat blood-dryness type seborrheic dermatitis.Seborrheic dermatitis belongs to the traditional Chinese medical science " seborrhea ichthyosis ", " seborrheic dermatitis " category.Wind heat blood-dryness type seborrheic dermatitis, due to the dry cloudy wound of blood usually, is felt wind heat again, strongly fragrant for a long time then dryness-transformation, failure of skin and muscle to be nourished, even ailment said due to cold or exposure is strongly fragrant for a long time, hematozemia impairment of YIN, skin loses that in child, to support raw air slaking dry, both reciprocal causations, so that pachylosis, show as dryness skin lesion more.
The object of the invention is to be achieved through the following technical solutions, the Chinese medicinal liniment of this treatment wind heat blood-dryness type seborrheic dermatitis is made by the Chinese medicine of following weight portion: Herba Ainsliaeae Fragrantis 12-16 part, Gentiana rhodantha Franch. 9-15 part, Herba Odontitis Serotinae 3-9 part, Herba Dracocephali Rupestris 7-10 part, Herba Apii graveolentis 9-15 part, Radix panici repentics 30-40 part, Herba Erigerontis Canadensis (Herba Conyzae Canadensis) 25-35 part, Herba Moslae Cavaleriei 9-15 part, Herba dauci carotae (Fructus Dauci Carotae) 6-10 part.
Preferred: 14 parts of Herba Ainsliaeae Fragrantiss, 12 parts of Gentiana rhodantha Franch.s, 6 parts of Herba Odontitis Serotinae, 8.5 parts of Herba Dracocephali Rupestriss, 12 parts of Herba Apii graveolentis, 35 parts of Radix panici repentics, 30 parts of Herba Erigerontis Canadensis (Herba Conyzae Canadensisies, 12 parts of Herba Moslae Cavalerieis, 8 parts of Herba dauci carotae (Fructus Dauci Carotae)s.
Preparation method is soaked above-mentioned Chinese crude drug after 30min, decocts the 1st 1h 3 times, 2nd, 3 each 40min, merge 3 times decocting liquid, filter, under the condition of 50 ℃, it is 1.20 that filtrate is concentrated into relative density, adds ethanol and makes to reach 60% containing alcohol amount, stir, static 24h, leaching supernatant, reclaim ethanol, simmer down to 200mL, and use flowing steam sterilization 30min, subpackage both obtained.
In side: Herba Ainsliaeae Fragrantis, Gentiana rhodantha Franch. clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body; Herba Odontitis Serotinae, Herba Dracocephali Rupestris's heat clearing and damp drying, cooling blood for hemostasis; Herba Apii graveolentis heat clearing away suppressing the hyperactive liver, expelling wind and removing dampness; Radix panici repentics heat clearing away suppressing the hyperactive liver, detoxification and promoting urination; Herba Erigerontis Canadensis (Herba Conyzae Canadensis) dispelling wind for relieving itching, anthelmintic removing toxic substances; Herba Moslae Cavaleriei dispelling wind for relieving itching, counteracting toxic substances, the skin ulcer that disappears swell; Herba dauci carotae (Fructus Dauci Carotae) killing parasites for relieving itching, detumescence.
Clinical data
1. the routine patient of physical data 86 all carrys out the medical patient of self-institute, wherein male's 44 examples, women's 42 examples, 6～64 years old age, average 37.1 years old, the course of disease 1 month～9 years, average 2.2 years, be divided at random treatment group and matched group, two groups of patients there was no significant difference (P>0.05) aspect age, sex, the course of disease, has comparability.
2. person between twenty and fifty are more common in diagnostic criteria (1), and the course of disease is chronic, outbreak repeatedly, time heavy when light.(2) be apt to occur in the position of being rich in sebaceous gland, as scalp, face, particularly eye, around mouth and nose, throat, oxter, front etc. locate.(3) skin lesion boundary is clear, and form is not of uniform size.From the beginning of being hair follicle red hillock recover around, then merge in flakes, typical skin lesion is yellowish red color or pale red patch, coated with greasy or dryness squama and crust, severe patient can be with alopecia.(4) conscious pruritus in various degree.(5) Chinese medical discrimination disease: skin lesion is yellowish red color, dry desquamation macule, has a large amount of canescence pityrosporum sample squamas at head, hair is withered to come off, and red tongue tongue is few, stringy and rolling pulse.
3. Therapeutic Method treatment group patient uses Chinese medicinal liniment of the present invention, takes Herba Ainsliaeae Fragrantis 14g, Gentiana rhodantha Franch. 12g, Herba Odontitis Serotinae 6g, Herba Dracocephali Rupestris 8.5g, Herba Apii graveolentis 12g, Radix panici repentics 35g, Herba Erigerontis Canadensis (Herba Conyzae Canadensis) 30g, Herba Moslae Cavaleriei 12g, Herba dauci carotae (Fructus Dauci Carotae) 8g.Above Chinese crude drug is soaked after 30min, decocts the 1st 1h 3 times, 2nd, 3 each 40min, merge 3 times decocting liquid, filter, under the condition of 50 ℃, it is 1.20 that filtrate is concentrated into relative density, adds ethanol and makes to reach 60% containing alcohol amount, stir, static 24h, leaching supernatant, reclaim ethanol, simmer down to 200mL, and use flowing steam sterilization 30min, subpackage both obtained.Patient gets this product every day and is evenly applied in affected part, massages every day twice, continuous 4 weeks 5 minutes.Matched group patient uses Xi Ersheng (selenium sulfide lotion), new Asia, Shanghai, port Pharmaceutical (Yangzhou) company limited; The accurate word of traditional Chinese medicines: H10890059.Patient is first drenched hair with clear water, then smears Xi Ersheng lotion, and employing is rubbed, the method for massaging scalp, after 5min, with clear water, rinses.2 times weekly, after continuous 4 weeks (8 times), carry out efficacy determination.
4. criterion of therapeutical effect (1) is cured: transference cure, skin lesion disappears completely.(2) effective: symptom obviously alleviates, skin lesion is clearly better.(3) effective: symptom, skin lesion take a favorable turn.(4) invalid: symptom, skin lesion be without improvement, though or skin lesion alleviate and still have new skin lesion to occur.
5. two groups of patient treatments of therapeutic effect carry out curative effect comparison after 4 weeks, and treatment group 43 examples are wherein cured 28 examples (65.1%), 14 examples that take a turn for the better (32.6%), invalid 1 example (2.3%), total effective rate 97.7%.Matched group 43 examples, wherein cure 12 examples (27.9%), 24 examples that take a turn for the better (55.8%), invalid 7 examples (16.3%), total effective rate 83.7%.Two groups of comparisons, treatment group cure rate, total effective rate are obviously better than matched group, have comparability (P<0.05).
The specific embodiment
Embodiment mono-: take Herba Ainsliaeae Fragrantis 14g, Gentiana rhodantha Franch. 12g, Herba Odontitis Serotinae 6g, Herba Dracocephali Rupestris 8.5g, Herba Apii graveolentis 12g, Radix panici repentics 35g, Herba Erigerontis Canadensis (Herba Conyzae Canadensis) 30g, Herba Moslae Cavaleriei 12g, Herba dauci carotae (Fructus Dauci Carotae) 8g.Above Chinese crude drug is soaked after 30min, decocts the 1st 1h 3 times, 2nd, 3 each 40min, merge 3 times decocting liquid, filter, under the condition of 50 ℃, it is 1.20 that filtrate is concentrated into relative density, adds ethanol and makes to reach 60% containing alcohol amount, stir, static 24h, leaching supernatant, reclaim ethanol, simmer down to 200mL, and use flowing steam sterilization 30min, subpackage both obtained.
Embodiment bis-: take Herba Ainsliaeae Fragrantis 16g, Gentiana rhodantha Franch. 9g, Herba Odontitis Serotinae 9g, Herba Dracocephali Rupestris 10g, Herba Apii graveolentis 15g, Radix panici repentics 30g, Herba Erigerontis Canadensis (Herba Conyzae Canadensis) 25g, Herba Moslae Cavaleriei 9g, Herba dauci carotae (Fructus Dauci Carotae) 10g, preparation method is with embodiment mono-.
Embodiment tri-: take Herba Ainsliaeae Fragrantis 12g, Gentiana rhodantha Franch. 15g, Herba Odontitis Serotinae 3g, Herba Dracocephali Rupestris 7g, Herba Apii graveolentis 9g, Radix panici repentics 40g, Herba Erigerontis Canadensis (Herba Conyzae Canadensis) 35g, Herba Moslae Cavaleriei 15g, Herba dauci carotae (Fructus Dauci Carotae) 6g, preparation method is with embodiment mono-.
Claims (2)
1. treat a Chinese medicinal liniment for wind heat blood-dryness type seborrheic dermatitis, it is characterized in that this Chinese medicinal liniment made by the Chinese medicine of following weight portion: Herba Ainsliaeae Fragrantis 12-16 part, Gentiana rhodantha Franch. 9-15 part, Herba Odontitis Serotinae 3-9 part, Herba Dracocephali Rupestris 7-10 part, Herba Apii graveolentis 9-15 part, Radix panici repentics 30-40 part, Herba Erigerontis Canadensis (Herba Conyzae Canadensis) 25-35 part, Herba Moslae Cavaleriei 9-15 part, Herba dauci carotae (Fructus Dauci Carotae) 6-10 part.
2. a kind of Chinese medicinal liniment for the treatment of wind heat blood-dryness type seborrheic dermatitis as claimed in claim 1, is characterized in that this Chinese medicinal liniment made by the Chinese medicine of following weight portion: 14 parts of Herba Ainsliaeae Fragrantiss, 12 parts of Gentiana rhodantha Franch.s, 6 parts of Herba Odontitis Serotinae, 8.5 parts of Herba Dracocephali Rupestriss, 12 parts of Herba Apii graveolentis, 35 parts of Radix panici repentics, 30 parts of Herba Erigerontis Canadensis (Herba Conyzae Canadensisies, 12 parts of Herba Moslae Cavalerieis, 8 parts of Herba dauci carotae (Fructus Dauci Carotae)s.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104689141A (en) * | 2015-04-07 | 2015-06-10 | 范永启 | Compound tea tree essential oil capable of achieving therapeutic effect on seborrheic dermatitis and preparation method thereof |
| CN104873765A (en) * | 2015-05-28 | 2015-09-02 | 王玉波 | Traditional Chinese medicine liniment for treating head-wind white scaling |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1954859A (en) * | 2005-10-26 | 2007-05-02 | 西乌珠穆沁旗蒙医医院 | Mongolia medicine composite for treating chronic cholecystitis, cholecystalgia and its method |
| CN101947259A (en) * | 2010-01-11 | 2011-01-19 | 徐林猛 | Chinese medicine preparation for treating cholecystitis |
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- 2014-01-12 CN CN201410020766.6A patent/CN103751613B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1954859A (en) * | 2005-10-26 | 2007-05-02 | 西乌珠穆沁旗蒙医医院 | Mongolia medicine composite for treating chronic cholecystitis, cholecystalgia and its method |
| CN101947259A (en) * | 2010-01-11 | 2011-01-19 | 徐林猛 | Chinese medicine preparation for treating cholecystitis |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104689141A (en) * | 2015-04-07 | 2015-06-10 | 范永启 | Compound tea tree essential oil capable of achieving therapeutic effect on seborrheic dermatitis and preparation method thereof |
| CN104873765A (en) * | 2015-05-28 | 2015-09-02 | 王玉波 | Traditional Chinese medicine liniment for treating head-wind white scaling |
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| CN103751613B (en) | 2016-06-08 |
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Effective date of registration: 20170516 Address after: Nanjing road 226100 Jiangsu Sijia town of Haimen city of Nantong province No. 78 Patentee after: HAIMEN RUITAI TEXTILE TECHNOLOGY Co.,Ltd. Address before: 271016 middle of the Great Wall Road, Shandong, Tai'an Province, Taishan Medical University Patentee before: You Guirong |
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