CN103194341A - Low-irritation baical skullcap root skin care soap - Google Patents
Low-irritation baical skullcap root skin care soap Download PDFInfo
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- CN103194341A CN103194341A CN2013101490272A CN201310149027A CN103194341A CN 103194341 A CN103194341 A CN 103194341A CN 2013101490272 A CN2013101490272 A CN 2013101490272A CN 201310149027 A CN201310149027 A CN 201310149027A CN 103194341 A CN103194341 A CN 103194341A
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Abstract
The invention discloses a low-irritation baical skullcap root skin care soap. The soap comprises the following raw materials in parts by weight: 0.05-0.15 part of baical skullcap root extract, 15-25 parts of sodium cocoate, 50-70 parts of sodium palmitate, 3-5 parts of N-oleoyl-N-sodium methyl taurate, 3-5 parts of olivamidopropylamine oxide and 20 parts of water. The low-irritation baical skullcap root skin care soap is exquisite and stable in foam, has mild properties and low skin irritation and can further moisten and protect the skin especially after the baical skullcap root extract is added.
Description
Technical field:
The present invention relates to a kind of perfumed soap, particularly the low skin care scented soap that stimulates of a kind of root of large-flowered skullcap.
Background technology:
Perfumed soap (soap) is one of skin, hair washing and nursing article, is a kind of daily necessities.Perfumed soap is to be main raw material with sodium soap and other tensio-active agents, adds quality improver and outward appearance modifying agent, through the product of making after the machine-shaping.
Perfumed soap is requisite washing and nursing article in the daily life, is main raw material with sodium soap and other tensio-active agents, adds quality improver and outward appearance modifying agent, through the product of making after the machine-shaping.The function of perfumed soap is the cleaning washing, be used in that yes above the skin and remove earth dirt, skin secretion, movement, chemical substance or bacterium etc., in today of stressing cosmetic result, makeup, skin care products or the medicine of removing skin surface also are one of its main purposes.
In the prior art, the many insights of perfumed soap are that fatty acid sodium salt is the Cake-shape soap of soap base, though have cleaning force, whipability and easy washability preferably, but not anti-hard water, can produce incrustation scale during washing, form the calcium magnesium soap, degreasing power is strong, the soap of human body life-time service meta-alkalescence can make skin feel dry and astringent, and excitement is arranged.
Root of large-flowered skullcap another name Radix Scutellariae, tsuchikane tea root.For the labiate root of large-flowered skullcap (Scutellaria baicalensis Georgi), be used as medicine with root.Heat-clearing and damp-drying drug is arranged, and cool blood is antiabortive, detoxicating functions.Cure mainly diseases such as febrile disease, upper respiratory tract infection, cough due to lung-heat, damp and hot jaundice, pneumonia, dysentery, hemoptysis, hot eyes, threatened abortion, hypertension, the swollen furuncle sore of carbuncle.
The pharmacological action of the root of large-flowered skullcap
1. cure mainly relevant pharmacological action with effect
(1) antibiotic, antiviral
1. scutellarin, wogonoside unit.
2. external: that multiple gram positive organism, gram-negative bacteria, pathogenic dermatophytes are had restraining effect.
3. antiviral: as to suppress influenza virus, hepatitis B virus.
(2) anti-inflammatory
Scutellarin, baicalin → inhibition acute inflammatory reaction.The inflammation-inhibiting model oozes out swelling, capillary permeability increases; Suppress rat assist agent arthritis.
1) mechanism: suppress inflammatory mediator and produce, discharge.
2) suppress histamine release
3) anti-arachidonic acid metabolism suppresses the generation of PGE (PGE), leukotrienes (LT), alleviates the inflammatory mediator vasodilation, increases vessel wall permeability, leukocytic chemotaxis.
(3) to Immune Effects
Suppress immune response: especially to I allergic reaction type (anaphylaxis) effect significantly.
The effect link:
1. stablize mast cell membrane, reduce inflammatory mediator and discharge.
2. influence arachidonic acid metabolism, suppress the generation of inflammatory mediator.
Improve body's immunity: baicalin, improve scavenger cell, NK cell function.
(4) analgesic.
(5) protect the liver, cholagogic (clearing liver courage): protect the liver: relevant with antioxidant radical damage.
(6) calmness: maincenter suppresses.
(7) blood system is influenced
Effect is complicated: scutellarin etc. → anticoagulant; Scutellarins etc. → anticoagulation: the scleroproein of anticoagulant enzyme induction produces.
Brief summary:
Antipathogen, anti-inflammatory, adjusting immunologic function, analgesic, calm, protect the liver, cholagogic etc.No antitumor action.
2. other pharmacological actions
(1) reducing blood-fat, atherosclerosis
Flavones ingredient.Reduce serum total cholesterol (TC), reduce serum triglyceride (TG) content, rising serum high-density LP cholesterol (HDL-C); Atherosclerosis.
(2) antioxidant radical damage: suppress the generation of lipid peroxide (LPO), remove free radical.
(3) step-down: directly expand peripheral blood vessel; Suppress vasomotor center.
Modern study proves that the root of large-flowered skullcap mainly contains baicaline, scutellarin, wogonin, compositions such as Wogonoside, neobaicalein, β-Gu Zaichun.Its antimicrobial spectrum is wider, and various bacteria, dermatophytes, Leptospira etc. are had restraining effect.Even it is to the streptococcus aureus that microbiotic such as penicillin develop immunity to drugs, still very sensitive to the root of large-flowered skullcap.The root of large-flowered skullcap hypotensive, calm, diuresis in addition, protect the liver, effect such as cholagogic, antianaphylaxis, releasing smooth muscle spasm.Use the respiratory tract infection of scutellaria for treating children's acute, infectious hepatitis, chronic tracheitis, acute bacillary dysentery, pyelonephritis etc. clinically, all can obtain good effect.
Yet, a kind of middle medicated perfumed soap is not arranged, contain root of large-flowered skullcap composition.
Summary of the invention:
At the prior art above shortcomings, technical problem to be solved by this invention provides the low skin care scented soap that stimulates of a kind of root of large-flowered skullcap.
Technical problem of the present invention is achieved by following technical proposals:
A kind of root of large-flowered skullcap hangs down stimulates skin care scented soap, comprises the raw material of following weight part: Radix Scutellariae extract 0.05-0.15 part, coconut oil sodium 15-25 part; Sodium pentadecanecarboxylate 50-70 part; N-oleoyl-N methyl taurine sodium 3-5 part, sweet oil acid amides propylamine oxide compound 3-5 part, 20 parts in water.
Preferably; the low skin care scented soap that stimulates of a kind of root of large-flowered skullcap; the raw material that comprises following weight part: Radix Scutellariae extract 0.05-0.15 part; sequestrant 0.5-1.5 part; N-oleoyl-N methyl taurine sodium 3-5 part, sweet oil acid amides propylamine oxide compound 3-5 part, coconut oil sodium 15-25 part; Sodium pentadecanecarboxylate 50-70 part, 20 parts in water.
Described sequestrant is made of by weight following component: methylglycine oxalic acid trisodium salt 40-60 part and hydroxyethyl diamine tetraacethyl trisodium salt 40-60 part.
Below, part material involved in the present invention is made simple declaration:
Radix Scutellariae extract of the present invention can pass through commercially available getting, as the Radix Scutellariae extract of Shenzhen BoDun spice Co., Ltd's production.This Radix Scutellariae extract also can adopt following method preparation and get: after the root of large-flowered skullcap is pulverized, the deionized water that adds the 6-10 times of weight, soaked 1-3 hour, ultrasonic extraction 10-15 minute, filter, centrifugal, discard precipitation with supernatant concentration, make Radix Scutellariae extract, control Radix Scutellariae extract density is at 1.05g/cm
3About.
N-oleoyl-N methyl taurine sodium, CAS accession number: 137-20-2.
Sweet oil acid amides propylamine oxide compound, CAS accession number: 124046-32-8.
Described methylglycine oxalic acid trisodium salt, CAS accession number: 170492-24-7, its English name: L-Alanine, N, N-bis (carboxymethyl)-, sodium salt (1:3).It has better biological degradability than sequestrant EDTA, NTA commonly used, and is more stable under wideer PH scope and high temperature, has higher calcium sequestration capacity, and inorganic sediment is had higher solubility property, and heavy metal is had sequestering power preferably.The Trilon that selects for use BASF AG to produce in the present invention
M liquid.
Described hydroxyethyl diamine tetraacethyl trisodium salt, CAS accession number: 207386-87-6, its English name: Glycine, N-[2-[bis (carboxymethyl) amino] ethyl]-N-(2-hydroxyethyl)-, trisodium salt, hydrate (9CI).
In addition, in the present invention, can also add other functional ingredient commonly used in the common perfumed soap, for example: antiseptic-germicide, pigment, essence, oxidation inhibitor, titanium dioxide etc., to realize corresponding function respectively.As add the antiseptic-germicide of 0.2-0.8 weight part, the antioxidant of 0.05-0.20 weight part, the sanitas of 0.02-0.2 weight part, the white dyes of the titanium dioxide of 0.02-2 weight part, 0.001-0.05 weight part or the essence of 0.2-1.2 weight part on prescription of the present invention basis.
The low skin care scented soap that stimulates of the root of large-flowered skullcap of the present invention can adopt the general soapmaking step of the common perfumed soap of the industry to be prepared, as:
(a) spice of kneading: the various raw materials of said components are taken by weighing in proportion join in the kneading machine that conventional soapmaking uses, kneading mixes.
(b) grind: the material after mixing will kneaded, enter in the shredder, carry out soap body and grind.
(c) vacuum press strip: the soap body after will grinding, enter vacuum plodder, carry out the vacuum press strip.
(d) print: the rectangular soap body that plodder extrudes directly enters printer and prints, and obtains the soap body of moulding.
The low skin care scented soap that stimulates of the root of large-flowered skullcap of the present invention, foam is fine and smooth stable, the performance gentleness is low to the pungency of skin, add Radix Scutellariae extract especially after, more can moisten and protect skin.
Embodiment:
Following embodiment further specifies of the present invention, rather than limits the scope of the invention.In the present invention, if no special instructions, each raw material is 100% in working substance content all.
Embodiment 1
Embodiment 1 data by table 1 correspondence take by weighing each raw material.
(a) spice of kneading: various raw materials are joined soap with in the kneading machine, and kneading mixes.
(b) grind: the material after mixing will kneaded, enter in the shredder, carry out soap body and grind.
(c) vacuum press strip: the soap body after will grinding, enter vacuum plodder, carry out the vacuum press strip.
(d) print: the rectangular soap body that plodder extrudes directly enters printer and prints, and obtains the soap body of moulding.
Embodiment 2
Embodiment 2 data by table 1 correspondence take by weighing each raw material.Method by embodiment 1 prepares perfumed soap.
Embodiment 3
Embodiment 3 data by table 1 correspondence take by weighing each raw material.Method by embodiment 1 prepares perfumed soap.
Embodiment 4
Embodiment 4 data by table 1 correspondence take by weighing each raw material.Method by embodiment 1 prepares perfumed soap.
Comparative Examples 1
Comparative Examples 1 data by table 1 correspondence take by weighing each raw material.Method by embodiment 1 prepares perfumed soap.
Table 1: perfumed soap formula table unit: kilogram
| ? | Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 | Comparative Examples 1 |
| Radix Scutellariae extract | 0.1 | 0.1 | 0.1 | 0.1 | 0.1 |
| Coconut oil sodium | 20 | 20 | 20 | 20 | 20 |
| Sodium pentadecanecarboxylate | 60 | 60 | 60 | 60 | 60 |
| N-oleoyl-N methyl taurine sodium | 4 | 4 | 4 | 4 | / |
| Sweet oil acid amides propylamine oxide compound | 4 | 4 | 4 | 4 | / |
| Methylglycine oxalic acid trisodium salt | / | 1 | / | 0.5 | / |
| Hydroxyethyl diamine tetraacethyl trisodium salt | / | / | 1 | 0.5 | / |
| Water | 20 | 20 | 20 | 20 | 20 |
Test case 1:
Experiment is 5wt% with soap lye concentration, and when consumption was 0.3ml, by HET VAM measurements determination skin reaction classification (values classification relatively), intense stimulus＞2.0 stimulated 1.2-2.0, medium stimulation 0.8-1.2, minimal irritation 0.0-0.8.
Use the Luo Shi Latherometer to carry out the foaming properties test, soap lye concentration is 2.5wt%, tests the foam height of 0 minute and 5 minutes respectively.
Table 2: test data table
The test data of experiment of associative list 2, the present invention selects N-oleoyl-N methyl taurine sodium and sweet oil acid amides propylamine oxide compound built-up soap fundamental mode anion surfactant coconut oil sodium and Sodium pentadecanecarboxylate for use initiatively, can effectively reduce the pungency of perfumed soap; Select the composite interpolation of sequestrant methylglycine oxalic acid trisodium salt and hydroxyethyl diamine tetraacethyl trisodium salt initiatively for use, further can promote foaming power and the foam stability of perfumed soap.Above-mentioned difference technical characterictic did not have open in the prior art, was not common practise yet.
Claims (3)
1. the low skin care scented soap that stimulates of the root of large-flowered skullcap is characterized in that, comprises the raw material of following weight part: Radix Scutellariae extract 0.05-0.15 part; coconut oil sodium 15-25 part, Sodium pentadecanecarboxylate 50-70 part, N-oleoyl-N methyl taurine sodium 3-5 part; sweet oil acid amides propylamine oxide compound 3-5 part, 20 parts in water.
2. root of large-flowered skullcap perfumed soap as claimed in claim 1; it is characterized in that; the raw material that comprises following weight part: Radix Scutellariae extract 0.05-0.15 part; sequestrant 0.5-1.5 part; N-oleoyl-N methyl taurine sodium 3-5 part, sweet oil acid amides propylamine oxide compound 3-5 part, coconut oil sodium 15-25 part; Sodium pentadecanecarboxylate 50-70 part, 20 parts in water.
3. the root of large-flowered skullcap as claimed in claim 2 hangs down stimulates skin care scented soap, it is characterized in that: described sequestrant, formed by weight by following component: methylglycine oxalic acid trisodium salt 40-60 part and hydroxyethyl diamine tetraacethyl trisodium salt 40-60 part.
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| CN201310149027.2A CN103194341B (en) | 2013-04-25 | 2013-04-25 | Low-irritation baical skullcap root skin care soap |
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| CN201310149027.2A CN103194341B (en) | 2013-04-25 | 2013-04-25 | Low-irritation baical skullcap root skin care soap |
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| CN103194341A true CN103194341A (en) | 2013-07-10 |
| CN103194341B CN103194341B (en) | 2014-12-24 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107312640A (en) * | 2017-07-05 | 2017-11-03 | 芜湖慧宇商贸有限公司 | A kind of preparation method of the Traditional Chinese medicine laundry detergent containing Baical Skullcap root P.E |
| CN111449989A (en) * | 2020-05-14 | 2020-07-28 | 上海应用技术大学 | Whitening and moisturizing face cleaning powder and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4743395A (en) * | 1986-09-12 | 1988-05-10 | The Drackett Company | Thickened acid cleaner compositions containing quaternary ammonium germicides and having improved thermal stability |
| CN101077079A (en) * | 2006-05-25 | 2007-11-28 | 西安格润森生物制药股份有限公司 | Plant-type antibacterial agent |
| CN102363740A (en) * | 2010-12-10 | 2012-02-29 | 江南大学 | Low-irritation and high-foaminess fancy soap formula |
-
2013
- 2013-04-25 CN CN201310149027.2A patent/CN103194341B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4743395A (en) * | 1986-09-12 | 1988-05-10 | The Drackett Company | Thickened acid cleaner compositions containing quaternary ammonium germicides and having improved thermal stability |
| CN101077079A (en) * | 2006-05-25 | 2007-11-28 | 西安格润森生物制药股份有限公司 | Plant-type antibacterial agent |
| CN102363740A (en) * | 2010-12-10 | 2012-02-29 | 江南大学 | Low-irritation and high-foaminess fancy soap formula |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107312640A (en) * | 2017-07-05 | 2017-11-03 | 芜湖慧宇商贸有限公司 | A kind of preparation method of the Traditional Chinese medicine laundry detergent containing Baical Skullcap root P.E |
| CN111449989A (en) * | 2020-05-14 | 2020-07-28 | 上海应用技术大学 | Whitening and moisturizing face cleaning powder and preparation method thereof |
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| Publication number | Publication date |
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| CN103194341B (en) | 2014-12-24 |
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Inventor after: Cao Dakang Inventor before: Huang Meirong |
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| TR01 | Transfer of patent right |
Effective date of registration: 20171122 Address after: 225000 Guangling District, Yangzhou City, Jiangsu Province, Sha Tau Town Patentee after: The vertical daily use chemicals company limited in Eurasia, Jiangsu Address before: 201604 Shanghai Songjiang District Shihudang mayor road 1000 Lane 2, room 219 Patentee before: Shanghai Bafang Fine Chemical Engineering Co., Ltd. |