CN103189745B - 肾损伤的生物标记物 - Google Patents

肾损伤的生物标记物 Download PDF

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Publication number
CN103189745B
CN103189745B CN201180053315.7A CN201180053315A CN103189745B CN 103189745 B CN103189745 B CN 103189745B CN 201180053315 A CN201180053315 A CN 201180053315A CN 103189745 B CN103189745 B CN 103189745B
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renal
risk
threshold
use according
urinary
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CN103189745A (zh
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K·辛格巴特尔
J·A·科勒姆
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University of Pittsburgh
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University of Pittsburgh
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475Assays involving growth factors
    • G01N2333/495Transforming growth factor [TGF]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70578NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30 CD40 or CD95
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/38Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence, e.g. gluco- or galactomannans, Konjac gum, Locust bean gum or Guar gum
    • G01N2400/40Glycosaminoglycans, i.e. GAG or mucopolysaccharides, e.g. chondroitin sulfate, dermatan sulfate, hyaluronic acid, heparin, heparan sulfate, and related sulfated polysaccharides
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/34Genitourinary disorders
    • G01N2800/347Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/50Determining the risk of developing a disease

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
CN201180053315.7A 2010-09-24 2011-09-19 肾损伤的生物标记物 Active CN103189745B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US38623010P 2010-09-24 2010-09-24
US61/386,230 2010-09-24
US13/235,005 US10557856B2 (en) 2010-09-24 2011-09-16 Biomarkers of renal injury
US13/235,005 2011-09-16
PCT/US2011/052082 WO2012040073A2 (en) 2010-09-24 2011-09-19 Biomarkers of renal injury

Publications (2)

Publication Number Publication Date
CN103189745A CN103189745A (zh) 2013-07-03
CN103189745B true CN103189745B (zh) 2018-05-01

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US (3) US10557856B2 (enExample)
EP (1) EP2619577B1 (enExample)
JP (1) JP5998143B2 (enExample)
KR (1) KR101981745B1 (enExample)
CN (1) CN103189745B (enExample)
AU (1) AU2011305786B2 (enExample)
BR (1) BR112013006935B1 (enExample)
CA (1) CA2811658C (enExample)
EA (1) EA030622B1 (enExample)
MX (1) MX365029B (enExample)
NZ (1) NZ608384A (enExample)
WO (1) WO2012040073A2 (enExample)

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Publication number Publication date
AU2011305786A1 (en) 2013-04-11
EP2619577A2 (en) 2013-07-31
US20200150132A1 (en) 2020-05-14
CN103189745A (zh) 2013-07-03
BR112013006935A2 (pt) 2017-05-30
CA2811658C (en) 2021-03-30
EP2619577B1 (en) 2017-08-16
CA2811658A1 (en) 2012-03-29
KR20140001863A (ko) 2014-01-07
US11693014B2 (en) 2023-07-04
JP2013539030A (ja) 2013-10-17
AU2011305786B2 (en) 2015-04-23
EA201390439A1 (ru) 2013-09-30
EA030622B1 (ru) 2018-09-28
NZ608384A (en) 2014-12-24
US20240118289A1 (en) 2024-04-11
KR101981745B1 (ko) 2019-05-27
EP2619577A4 (en) 2014-04-30
US10557856B2 (en) 2020-02-11
MX2013003321A (es) 2013-10-25
WO2012040073A2 (en) 2012-03-29
MX365029B (es) 2019-05-21
WO2012040073A3 (en) 2012-06-14
BR112013006935B1 (pt) 2021-02-23
JP5998143B2 (ja) 2016-09-28
US20120077690A1 (en) 2012-03-29

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