CN103153286A - 药物组合物及其施用 - Google Patents

药物组合物及其施用 Download PDF

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Publication number
CN103153286A
CN103153286A CN2011800475471A CN201180047547A CN103153286A CN 103153286 A CN103153286 A CN 103153286A CN 2011800475471 A CN2011800475471 A CN 2011800475471A CN 201180047547 A CN201180047547 A CN 201180047547A CN 103153286 A CN103153286 A CN 103153286A
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pharmaceutical composition
weight
compound
solid dispersion
composition
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CN2011800475471A
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English (en)
Chinese (zh)
Inventor
E·多考
S·詹姆扎得
L·达斯
M·J·伊斯兰尼
D·克内日奇
A·G·库兹米森
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Vertex Pharmaceuticals Inc
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Vertex Pharmaceuticals Inc
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Publication of CN103153286A publication Critical patent/CN103153286A/zh
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  • Veterinary Medicine (AREA)
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  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
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  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Reproductive Health (AREA)
  • Psychology (AREA)
  • Inorganic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Otolaryngology (AREA)
  • Pain & Pain Management (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Ophthalmology & Optometry (AREA)
  • Psychiatry (AREA)
CN2011800475471A 2010-08-27 2011-08-26 药物组合物及其施用 Pending CN103153286A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US37787310P 2010-08-27 2010-08-27
US61/377,873 2010-08-27
PCT/US2011/049467 WO2012027731A2 (en) 2010-08-27 2011-08-26 Pharmaceutical composition and administrations thereof

Publications (1)

Publication Number Publication Date
CN103153286A true CN103153286A (zh) 2013-06-12

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ID=44645205

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Application Number Title Priority Date Filing Date
CN2011800475471A Pending CN103153286A (zh) 2010-08-27 2011-08-26 药物组合物及其施用

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US (2) US20120064157A1 (cg-RX-API-DMAC10.html)
EP (1) EP2608775A2 (cg-RX-API-DMAC10.html)
JP (1) JP2013536251A (cg-RX-API-DMAC10.html)
CN (1) CN103153286A (cg-RX-API-DMAC10.html)
AU (1) AU2011293135A1 (cg-RX-API-DMAC10.html)
BR (1) BR112013004130A2 (cg-RX-API-DMAC10.html)
CA (1) CA2809263A1 (cg-RX-API-DMAC10.html)
MX (1) MX2013002353A (cg-RX-API-DMAC10.html)
NZ (1) NZ607494A (cg-RX-API-DMAC10.html)
RU (1) RU2013113627A (cg-RX-API-DMAC10.html)
WO (1) WO2012027731A2 (cg-RX-API-DMAC10.html)
ZA (1) ZA201301419B (cg-RX-API-DMAC10.html)

Cited By (2)

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CN116456968A (zh) * 2020-09-09 2023-07-18 克林提克斯医药股份有限公司 生长抑素调节剂的制剂
WO2024104031A1 (zh) * 2022-11-16 2024-05-23 四川科伦药业股份有限公司 一种枸橼酸西地那非口崩片及其生产制备方法

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* Cited by examiner, † Cited by third party
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US7973169B2 (en) 2003-09-06 2011-07-05 Vertex Pharmaceuticals Incorporated Modulators of ATP-Binding Cassette transporters
US7977322B2 (en) 2004-08-20 2011-07-12 Vertex Pharmaceuticals Incorporated Modulators of ATP-binding cassette transporters
CA2881078C (en) 2004-06-24 2018-10-02 Vertex Pharmaceuticals Incorporated Modulators of atp-binding cassette transporters
RU2008109031A (ru) 2005-08-11 2009-09-20 Вертекс Фармасьютикалз Инкорпорейтед (Us) Модуляторы муковисцидозного трансмембранного регулятора проводимости
PT2404919E (pt) 2005-11-08 2013-10-22 Vertex Pharma Composto heterocíclico útil como um modulador de transportadores de cassete de ligação a atp
LT1993360T (lt) 2005-12-28 2017-06-12 Vertex Pharmaceuticals Incorporated N-[2,4-bis(1,1-dimetiletil)-5-hidroksifenil]-1,4-dihidro-4-oksochinolin-3-karboksamido kieta forma
EP2016065B1 (en) 2005-12-28 2012-09-19 Vertex Pharmaceuticals Incorporated 1-(benzo[d][1,3]dioxol-5-yl)-n-(phenyl)cyclopropane-carboxamide derivatives and related compounds as modulators of atp-binding cassette transporters for the treatment of cystic fibrosis
US7645789B2 (en) * 2006-04-07 2010-01-12 Vertex Pharmaceuticals Incorporated Indole derivatives as CFTR modulators
USRE50453E1 (en) 2006-04-07 2025-06-10 Vertex Pharmaceuticals Incorporated Indole derivatives as CFTR modulators
JP5420395B2 (ja) 2006-04-07 2014-02-19 バーテックス ファーマシューティカルズ インコーポレイテッド Ａｔｐ結合カセット輸送体の調節剤
US10022352B2 (en) 2006-04-07 2018-07-17 Vertex Pharmaceuticals Incorporated Modulators of ATP-binding cassette transporters
US8563573B2 (en) * 2007-11-02 2013-10-22 Vertex Pharmaceuticals Incorporated Azaindole derivatives as CFTR modulators
EP2164840A2 (en) 2007-05-09 2010-03-24 Vertex Pharmaceuticals Incorporated Modulators of cftr
CA2696298C (en) 2007-08-24 2016-09-06 Vertex Pharmaceuticals Incorporated Modulators of cystic fibrosis transmembrane conductance regulator
CN102743385B (zh) 2007-11-16 2014-09-17 沃泰克斯药物股份有限公司 Atp结合盒转运蛋白的异喹啉调节剂
US20100036130A1 (en) 2007-12-07 2010-02-11 Vertex Pharmaceuticals Incorporated Processes for producing cycloalkylcarboxamido-pyridine benzoic acids
CA2989620C (en) 2007-12-07 2022-05-03 Vertex Pharmaceuticals Incorporated Processes for producing cycloalkylcarboxamido-pyridine benzoic acids
HUE049642T2 (hu) 2007-12-07 2020-09-28 Vertex Pharma 3-(6-(1-(2,2-Difluorbenzo[d][1,3]dioxol-5-il)-ciklopropánkarboxamido)-3-metilpiridin-2-il)-benzoesav szilárd formái
AU2008335439A1 (en) * 2007-12-07 2009-06-18 Vertex Pharmaceuticals Incorporated Formulations of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid
CA2716109C (en) 2008-02-28 2016-07-19 Vertex Pharmaceuticals Incorporated Heteroaryl derivatives as cftr modulators
NZ616097A (en) 2008-03-31 2015-04-24 Vertex Pharma Pyridyl derivatives as cftr modulators
US20100074949A1 (en) 2008-08-13 2010-03-25 William Rowe Pharmaceutical composition and administration thereof
US12458635B2 (en) 2008-08-13 2025-11-04 Vertex Pharmaceuticals Incorporated Pharmaceutical composition and administrations thereof
WO2010037066A2 (en) * 2008-09-29 2010-04-01 Vertex Pharmaceuticals Incorporated Dosage units of 3-(6-(1-(2,2-difluorobenzo [d] [1,3] dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid
MX2011004375A (es) 2008-10-23 2013-03-07 Vertex Pharma Moduladores del regulador de conductancia transmembrana de fibrosis quistica.
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