CN103141846A - Chicken heme microcapsule and manufacturing method thereof - Google Patents
Chicken heme microcapsule and manufacturing method thereof Download PDFInfo
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- CN103141846A CN103141846A CN2013101000269A CN201310100026A CN103141846A CN 103141846 A CN103141846 A CN 103141846A CN 2013101000269 A CN2013101000269 A CN 2013101000269A CN 201310100026 A CN201310100026 A CN 201310100026A CN 103141846 A CN103141846 A CN 103141846A
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Abstract
The invention belongs to the field of food processing, and in particular relates to a chicken heme microcapsule and a manufacturing method thereof. The manufacturing method provided by the invention can be used for solving the technical problem that current chicken blood is low in utilization ratio, and current chicken heme extraction method is large in toxic, high in cost, complex in process and not environmental-friendly. The technical scheme provided by the invention is as follows: the chicken heme microcapsule is mainly prepared from fresh chicken blood. Based on heme extracted from chicken blood as a core material and CMC-Na as a wall material, the raw material comprises the following components in parts by weight: 100 parts of fresh chicken blood, 1-4 parts of sodium citrate, 0.5-1.5 parts of alkaline protease and 25-50 parts of CMC-Na. The invention further provides a manufacturing method of the chicken heme microcapsule. The method comprises the following steps of: pre-treating, centrifugalizing, performing enzymolysis, deactivating enzyme, centrifugalizing, mixing, forming microcapsule, drying and packaging. The chicken heme microcapsule provided by the invention opens a novel path for comprehensively utilizing livestock processing byproducts.
Description
Technical field
The invention belongs to food processing field.Be specifically related to chicken ferroheme microcapsules and preparation method thereof.
Background technology
Blood is the byproduct in meat industry, and animal blood accounts for 8% of its body weight, butcher rear collectable blood account for its carcass heavy 4.5%.Animal blood contains abundant nutriment, protein especially, and its content can compare favourably with lean meat, so blood have the title of " liquid meat " in west, has good value.Along with China's bird industrial expansion, the annual production of chicken blood is considerable, but the discharge of most of form with discarded object.Not only cause the waste of resource, and caused serious environmental pollution.
Ferroheme is the important PORPHYRIN IRON compound of a class, extensively is present in animal blood, muscle and certain plants tissue.A lot of research about ferroheme at present mainly concentrates on ox blood and pig blood, and research contents comprises extracts the aspects such as ferroheme and purifying thereof, the domestic preparation that seldom has research to relate to chicken ferroheme microcapsules from ox blood, pig blood.The method for preparing at present ferroheme both at home and abroad has ultra-filtration and separation method, glacial acetic acid extraction method, pancreatin hydrolysis hemoglobin method, neutral proteinase and food flavor enzyme Hydrolyze method, pepsin or animal stomach lining to prepare edible heme etc.Utilize these chemical methodes to extract ferroheme and have the shortcomings such as toxicity is large, cost is high, complex process, not environmental protection.
A kind of preparation method of microcapsules iron-supplementing preparation is disclosed in " the extraction purifying of pig blood hemachrome and microcapsules are mended the preparation of chalybeate ".The method be take fresh pig blood and is passed through the standby ferroheme crude product of ultrasound wave auxiliary enzyme legal system as raw material, then through purification process such as oversalting, gel chromatographies, the ferroheme crude product made is further purified, finally the ferroheme obtained is carried out to encapsulation, prepare novel microcapsules iron-supplementing preparation.The ferroheme microcapsules that use ultrasonic wave assisted extraction ferroheme and microcapsules freeze-drying method to make in the method, but complete the equipment price costlinesses such as equipment ultrasonic cell disruption instrument that this technique needs, vacuum freeze drier, be more suitable for laboratory research.In ferroheme microcapsules preparation process, the time of vacuum freeze drying needs 13h simultaneously, and power consumption greatly.The deficiency of above-mentioned two aspects will limit the possibility of its suitability for industrialized production to a great extent.
For this area, for different target materials, character is different, needs suitable extraction ferroheme and the microencapsulation technology system of exploitation separately, to obtain satisfied product.And whether can adopt micro-encapsulation technology to prepare chicken ferroheme microcapsules for chicken blood, and how to prepare, have not been reported.
Summary of the invention
The technical problem to be solved in the present invention is that current chicken blood utilization rate is low, and the existing method toxicity of extracting ferroheme is large, cost is high, complex process, not environmental protection.
The technical scheme that the present invention solves first technical problem is to provide a kind of chicken ferroheme microcapsules.
The invention provides a kind of chicken ferroheme microcapsules, the ferroheme that the chicken blood of take extracts is core, usings the CMC-Na(sodium carboxymethylcellulose) as the wall material, be prepared from.
Above-mentioned chicken ferroheme microcapsules raw material used comprises by weight ratio: new freshly-slaughtered poultry blood is 100 parts, and natrium citricum is 1～4 part, and alkali protease is 0.5～1.5 part, and CMC-Na dry powder is 25～50 parts.
Preferably, raw materials usedly comprise by weight ratio: new freshly-slaughtered poultry blood is 100 parts, and natrium citricum is 1.5～3.5 parts, and alkali protease is 0.8～1.2 part, and CMC-Na dry powder is 30～45 parts.
Further preferred, raw materials usedly comprise by weight ratio: new freshly-slaughtered poultry blood is 100 parts, and natrium citricum is 3 parts, and alkali protease is 1.0 parts, and CMC-Na dry powder is 40 parts.
The present invention also provides the preparation method of above-mentioned chicken ferroheme microcapsules, comprises the following steps:
A, pretreatment: add sodium citrate solution in chicken blood, stir;
B, centrifugal: the chicken blood stirred is removed to crude fibre, take off a layer red blood cell blood plasma after centrifugal;
C, enzymolysis: add alkali protease in red blood cell blood plasma, enzymolysis, obtain hydrolyzate;
D, enzyme goes out: hydrolyzate, under 80～90 ℃ of conditions, heats 20～35min enzyme that goes out;
E, centrifugal: after the hydrolyzate after the enzyme that goes out is cooling, the centrifugal supernatant that obtains;
F, mixing: supernatant is mixed with CMC-Na solution, and regulator solution pH is 4～5;
G, microcapsules moulding, drying, packing.
Wherein, in the preparation method of above-mentioned chicken ferroheme microcapsules, the mass percent of the described sodium citrate solution of step a is 1～4%.
Wherein, in the preparation method of above-mentioned chicken ferroheme microcapsules, step b is described centrifugal, is at the centrifugal 10～15min of 5000～10000r/min.
Wherein, in the preparation method of above-mentioned chicken ferroheme microcapsules, the described enzymolysis of step c, wherein enzyme is lived as 30000-50000U/g.
Wherein, in the preparation method of above-mentioned chicken ferroheme microcapsules, the described enzymolysis of step c, be at 40 ℃, Water Under solution 8～12h that the pH value is 9～11.
Wherein, in the preparation method of above-mentioned chicken ferroheme microcapsules, step e is described centrifugal, is at the centrifugal 10～15min of 3000～5000r/min.
Wherein, in the preparation method of above-mentioned chicken ferroheme microcapsules, the mass concentration of the described CMC-Na solution of step f is 1～3%.
Wherein, in the preparation method of above-mentioned chicken ferroheme microcapsules, use NaHCO in step f
3Regulate the pH value.
Wherein, in the preparation method of above-mentioned chicken ferroheme microcapsules, the concrete operations of step g comprise: mixed liquor drops into the spray dryer spray shaping, nozzle bore size 0.5～0.8mm, and washing obtains wet capsule; The wet spray-dried machine of capsule carries out drying, and the drying process technological parameter is: 150～200 ℃ of 60～80 ℃ of feeding temperatures, rotating speed 10000～15000r/min, EAT; After dry microcapsules metering, in vacuum, be 0.7～0.9MPa vacuum packaging, get product.
Beneficial effect of the present invention is: the present invention utilizes the byproduct production ferroheme in the processing of poultry meat both can improve the utilization rate of raiseeing blood resource, can reduce again and abandon the environmental pollution that a large amount of poultry blood causes.The present invention adopts enzyme process to prepare ferroheme, with organic solvent extraction methods such as traditional acetic acid, acid acetone, chloroforms, compare, the simple environmental protection of this preparation method, do not use toxic reagent, for meat products processing or man-hour that adds of mending iron class health food, there is higher edible safety.The present invention has also used microencapsulation technology to produce chicken ferroheme microcapsules, the extraction rate reached to 85% of ferroheme wherein, and embedding rate reaches 89.14%.The microcapsules of chicken ferroheme can directly be absorbed by intestinal mucosa cells, and solubility increases, and has higher bioavailability, and the microencapsulation of chicken ferroheme can improve the tolerance of ferroheme to ambient influnence simultaneously.It is raw material that new freshly-slaughtered poultry blood is take in the present invention, the ferroheme extracted wherein prepares microcapsules, to in medicine food, health products and cosmetic industry, have using value widely, greatly improved nutritive value and the range of application of ferroheme, this comprehensive utilization to the livestock and poultry processed side product will be also the development trend of meat product industry.In the present invention, preparation method's technique of chicken ferroheme microcapsules is simple, is suitable for industrialization and produces continuously, has more wide market prospects.
The specific embodiment
Chicken ferroheme microcapsules, the ferroheme that the chicken blood of take extracts is core, using the CMC-Na(sodium carboxymethylcellulose) as the wall material, be prepared from, raw materials usedly comprise by weight ratio: new freshly-slaughtered poultry blood is 100 parts, natrium citricum is 1～4 part, alkali protease is 0.5～1.5 part, and CMC-Na is 25～50 parts.
The preparation method of above-mentioned chicken ferroheme microcapsules comprises the following steps:
A, pretreatment: add the sodium citrate solution that mass percent is 1～4% in new freshly-slaughtered poultry blood, stir;
B, centrifugal: the chicken blood mixed is removed crude fibre, at the centrifugal 10～15min of 5000～10000r/min, takes off a layer red blood cell blood plasma;
C, enzymolysis: add alkali protease in red blood cell blood plasma, enzyme is lived as 30000-50000U/g, in temperature, is 40 ℃, Water Under solution 8～12h that the pH value is 9～11;
D, enzyme goes out: hydrolyzate, under 80～90 ℃ of conditions, heats 20～35min enzyme that goes out;
E, centrifugal: after the hydrolyzate after the enzyme that goes out is cooling, at the centrifugal 10～15min of 3000～5000r/min, obtain supernatant;
F, mixing: the CMC-Na solution that supernatant is 1～3% with mass concentration mixes, then uses NaHCO
3Regulator solution pH is 4～5;
G, microcapsules moulding, drying, packing: mixed liquor drops into the spray dryer spray shaping, nozzle bore size 0.5～0.8mm, and washing obtains wet capsule; The wet spray-dried machine of capsule carries out drying, wherein: 150～200 ℃ of 60～80 ℃ of feeding temperatures, rotating speed 10000～15000r/min, EAT; After dry microcapsules metering, in vacuum, be 0.7～0.9MPa vacuum packaging, get product.
Wherein, the sodium citrate solution that adds 1～4%wt is to use as anti-coagulants, if the citric acid use amount continues to increase, reconciles suitable pH while being unfavorable for enzymolysis process.
Alkali protease is the bacillus licheniformis 2709 gone out by the bacterium Protoplasts Mutagenesis, through submerged fermentation, extraction and the refining a kind of proteolytic enzyme formed, its Major Enzymes composition is bacillus licheniformis protease, a kind of nontoxic, protein of having no side effect, belong to serine-type inscribe egg, it can generate polypeptide or amino acid by aminosal molecule peptide chain, alkali protease is applied in food service industry hydrolyzable protein molecule peptide chain and generates polypeptide or amino acid, forms the protein hydrolyzate with peculiar flavour.The alkali protease CAS that uses in the present invention numbering: 9014-01-1, used under the alkali condition that to be suitable at 40～55 ℃, pH value be 9～11, and the vigor that exceeds above temperature and pH value scope enzyme can descend.
The factor that affects the rate of release of microcapsules is mainly wall material and core to the tolerance of gastro-intestinal Fluid pH and the molecular size range of wall material and core.In the preparation process of microcapsules, the composition of wall material with select most importantly to the character of microcapsules, and this is also one of the essential condition that obtains the microcapsule product of high microencapsulation efficiency, superior performance.For the apolegamy of wall material, at first consider wanting can be compatible but chemical reaction can not occur with core, and considers in addition the physico-chemical property of macromolecule embedded material self, as dissolubility.Hygroscopicity, stability, mechanical strength, film forming and emulsibility etc.; In addition, the also reasonable and easy preparation of dutiable value of wall material.Wall material commonly used can be divided into carbohydrate, hydrophilic colloid class and protein-based by its chemical property.Carbohydrate, comprise that starch, corn syrup solids, maltodextrin, shitosan, small molecular sugar class etc. are often used as microcapsule wall material, and this is because they still show lower viscosity when highly filled, and has good dissolubility.Hydrophilic colloid typically refers to and can be dissolved in water, and under certain condition fully aquation form the macromolecular substances of thickness, satiny or jelly solution, extensive use in food, medicine, chemical industry and other many fields.Hydrophilic colloid by sources can be divided into: the plant secretion thing, as pectin, guar gum, Arabic gum etc.; Microorganism fermentation, metabolite, as xanthans, gellan gum etc.; The algin extract, as carragheen, agar, alginate etc.Protein is used as the wall material and is widely used in the microcapsules field because it has good functional characteristic, and it can play and promote emulsion to form, and by reducing interfacial tension and form the effect that layer protecting film reaches the stable emulsion shape around oil droplet.The protein the most often used comprises the lactalbumin, casein, gelatin of animal origin etc., and the soybean protein of plant origin etc.Simultaneously, the initial soln that modulation is comprised of core and wall material is also very large on the impact of whole microencapsulation process.Its major influence factors comprises: the viscosity of mixed liquor, uniformity, the concentration of core and wall material, the ratio of formation core and wall material, the speed of spraying, spray method and rate of drying.
The present invention chooses the wall material of comparatively ideal compound as chicken ferroheme microcapsules through a large amount of previous experiments, at numerous gelatin and CMC-Na of filtering out in can be used as the material that the wall material uses as the wall material.Then filter out again viscosity, the uniformity of the applicable mixed liquor of gelatin and CMC-Na and chicken ferroheme by a large amount of preliminary experiments, the concentration of core and wall material, the ratio of formation core and wall material.Further by preliminary experiment, obtained again the preliminary addition of wall material: choose respectively gelatin and CMC-Na as the wall material, preparation chicken ferroheme microcapsules, gelatin solution and CMC-Na concentration of polymer solution are 1%, choose core wall mass ratio and be respectively 1:1,2:1,3:1,4:1, choosing the pH value is respectively 4,4.2,4.4,4.6,4.8,5.0 and prepares respectively microcapsules, then observe the form of microcapsules, measure the productive rate of microcapsules.Experiment draws, CMC-Na all has at least one can form the form pH condition of spherical microcapsule preferably in a plurality of core wall mass ratios, and therefore choosing CMC-Na is the wall material, and CMC-Na output is large, and cost is low.Take output as index, and corresponding CMC-Na addition when microcapsules output is maximum, tentatively be decided to be the addition of wall material.
Below in conjunction with embodiment, the present invention will be further described.
The spray dryer model of using in embodiments of the invention is GPQ-type spray-drying experimental machine, and manufacturer is: Qianjiang Drying Equipment Co., Ltd., Hangzhou.
Embodiment 1
(i) fill a prescription:
New freshly-slaughtered poultry blood 100kg, natrium citricum 1kg, alkali protease 0.5kg, CMC-Na 33.3kg.
(ii) manufacturing process:
A, pretreatment: new freshly-slaughtered poultry blood adds the 1%(mass ratio) the anti-coagulants sodium citrate solution, stir;
B, centrifugal: the chicken blood mixed is removed crude fibre by 120 order filtered through gauze, and filtrate is inserted in centrifuge, 5000r/min, and centrifugal 10min, take off a layer red blood cell blood plasma;
C, enzymolysis: add alkali protease in red blood cell blood plasma, red blood cell PC 3%(mass percent), the 0.5%(mass percent that enzyme concentration is red blood cell blood plasma), enzyme is lived as 50000U/g, and pH 9, in 40 ℃ of hydrolysis 9h;
D, enzyme goes out: 80 ℃ of heating 30min of hydrolyzate make the enzyme loss of activity;
E, centrifugal: after the enzyme that goes out, hydrolyzate is naturally cooling, and is placed on centrifuge, 3000r/min, and centrifugal 12min, obtain supernatant;
F, mixing: the CMC-Na solution that supernatant is 1% with mass concentration mixes, and mixing ratio (mass ratio) is 4:1, and pH is 4;
G, microcapsules moulding: mixed liquor drops into the spray dryer spray shaping, nozzle bore size 0.5mm, and washing obtains wet capsule;
Dry: the wet spray-dried machine of capsule carries out drying, and Operating parameters is: 200 ℃ of 60 ℃ of feeding temperatures, rotating speed 10000r/min, EAT.
Packing: after the microcapsules metering that drying obtains, vacuum packaging (vacuum 0.7-0.9MPa), get product.
Wherein, the extraction rate reached to 80% of chicken ferroheme, embedding rate is 84.79%.
Embodiment 2
(i) fill a prescription:
New freshly-slaughtered poultry blood 100kg, natrium citricum 2kg, alkali protease 1.5kg, CMC-Na 25kg.
(ii) manufacturing process:
A, pretreatment: new freshly-slaughtered poultry blood adds the 2%(mass ratio) the anti-coagulants sodium citrate solution, stir;
B, centrifugal: the chicken blood mixed is removed crude fibre by 120 order filtered through gauze, and filtrate is inserted centrifuge, 5000r/min, and centrifugal 12min, take off a layer red blood cell blood plasma;
C, enzymolysis: add alkali protease in red blood cell blood plasma, red blood cell PC 4%(mass percent), the 1.5%(mass percent that enzyme concentration is red blood cell blood plasma), enzyme is lived as 40000U/g, and pH 10, in 40 ℃ of hydrolysis 8h;
D, enzyme goes out: 85 ℃ of heating 20min of hydrolyzate make the enzyme loss of activity;
E, centrifugal: after the enzyme that goes out, hydrolyzate is naturally cooling, and is placed on centrifuge 3000r/min, and centrifugal 10min, obtain supernatant;
F, mixing: the CMC-Na solution that supernatant is 1% with concentration mixes, and mixing ratio (mass ratio) is 3:1, pH value of solution: 4.5;
G, microcapsules moulding: mixed liquor drops into the spray dryer spray shaping, nozzle bore size 0.6mm, and washing obtains wet capsule;
Dry: the wet spray-dried machine of capsule carries out drying, and Operating parameters is: 70 ℃ of feeding temperatures, turn 150 ℃ of 12000r/min, EATs.
Packing: after the microcapsules metering that drying obtains, vacuum packaging (vacuum 0.7-0.9MPa), get product.
Wherein, the extraction rate reached to 83% of chicken ferroheme, embedding rate is 86.05%.
Embodiment 3
(i) fill a prescription:
New freshly-slaughtered poultry blood 100kg, natrium citricum 3kg, alkali protease 1.5kg, CMC-Na 50kg.
(ii) manufacturing process:
A, pretreatment: new freshly-slaughtered poultry blood adds the 3%(mass ratio) the anti-coagulants sodium citrate solution, stir;
B, centrifugal: the chicken blood mixed is removed crude fibre by 120 order filtered through gauze, and filtrate is inserted centrifuge, 10 000r/min, and centrifugal 15min, take off a layer red blood cell blood plasma;
C, enzymolysis: add alkali protease in red blood cell blood plasma, red blood cell PC 5%(mass percent), the 1.5%(mass percent that enzyme concentration is red blood cell blood plasma), enzyme is lived as 50000U/g, and pH 9.0, in 40 ℃ of hydrolysis 12h;
D, enzyme goes out: 80 ℃ of heating 35min of hydrolyzate make the enzyme loss of activity;
E, centrifugal: after the enzyme that goes out, hydrolyzate is naturally cooling, and is placed on centrifuge 5000r/min, and centrifugal 15min, obtain supernatant;
F, mixing: the CMC-Na solution that supernatant is 1% with concentration mixes, and mixing ratio (mass ratio) is 2:1, pH value of solution 5;
G, microcapsules moulding: mixed liquor drops into the spray dryer spray shaping, nozzle bore size 0.8mm, and washing obtains wet capsule;
Dry: the wet spray-dried machine of capsule carries out drying, and Operating parameters is: 200 ℃ of feeding temperature 60-80 ℃, rotating speed 15000r/min, EAT.
Packing: after the microcapsules metering that drying obtains, vacuum packaging (vacuum 0.7-0.9MPa), get product.
Wherein, the extraction rate reached to 85% of ferroheme, embedding rate is 89.14%.
The chicken ferroheme microcapsules that method provided by the invention makes, in whole preparation process, not with an organic solvent, product safety is natural, is conducive to the consumer health.Chicken ferroheme microcapsules prepared by the present invention, form because of its microcapsules, make the contact area of its air less, adding of colloid its susceptibility to temperature is reduced simultaneously, than similar chicken ferroheme product, the chicken ferroheme existed with the microcapsules form strengthens the tolerance of air and high temperature.
Claims (10)
1. chicken ferroheme microcapsules is characterized in that: these microcapsules are that to take the ferroheme that chicken blood extracts be core, and the CMC-Na of usining is prepared from as the wall material.
2. chicken ferroheme microcapsules according to claim 1 is characterized in that: raw materials usedly comprise by weight ratio: new freshly-slaughtered poultry blood is 100 parts, and natrium citricum is 1～4 part, and alkali protease is 0.5～1.5 part, and CMC-Na dry powder is 25～50 parts;
Preferably, natrium citricum is 1.5～3.5 parts, and alkali protease is 0.8～1.2 part, and CMC-Na dry powder is 30～45 parts;
Preferably, natrium citricum is 3 parts, and alkali protease is 1.0 parts, and CMC-Na dry powder is 40 parts.
3. the preparation method of the described chicken ferroheme of claim 1 or 2 microcapsules is characterized in that: comprise the following steps:
A, pretreatment: add sodium citrate solution in chicken blood, stir;
B, centrifugal: the chicken blood stirred is removed to crude fibre, take off a layer red blood cell blood plasma after centrifugal;
C, enzymolysis: add alkali protease in red blood cell blood plasma, enzymolysis, obtain hydrolyzate;
D, enzyme goes out: hydrolyzate, under 80～90 ℃ of conditions, heats 20～35min enzyme that goes out;
E, centrifugal: after the hydrolyzate after the enzyme that goes out is cooling, the centrifugal supernatant that obtains;
F, mixing: supernatant is mixed with CMC-Na solution, and regulator solution pH is 4～5;
G, microcapsules moulding, drying, packing.
4. the preparation method of chicken ferroheme microcapsules according to claim 3, it is characterized in that: the mass percent of the described sodium citrate solution of step a is 1～4%.
5. the preparation method of chicken ferroheme microcapsules according to claim 3, it is characterized in that: step b is described centrifugal, is at the centrifugal 10～15min of 5000～10000r/min.
6. the preparation method of chicken ferroheme microcapsules according to claim 3 is characterized in that: the described enzymolysis of step c, wherein enzyme is lived as 30000-50000U/g.
7. the preparation method of chicken ferroheme microcapsules according to claim 3, it is characterized in that: the described enzymolysis of step c is at 40 ℃, Water Under solution 8～12h that pH is 9～11.
8. the preparation method of chicken ferroheme microcapsules according to claim 3, it is characterized in that: step e is described centrifugal, is at the centrifugal 10～15min of 3000～5000r/min.
9. the preparation method of chicken ferroheme microcapsules according to claim 3, it is characterized in that: the mass concentration of the described CMC-Na solution of step f is 1～3%.
10. the preparation method of chicken ferroheme microcapsules according to claim 3, it is characterized in that: the concrete operations of step g comprise: mixed liquor drops into the spray dryer spray shaping, nozzle bore size 0.5～0.8mm, washing obtains wet capsule; The wet spray-dried machine of capsule carries out drying, and the drying process technological parameter is: 150～200 ℃ of 60～80 ℃ of feeding temperatures, rotating speed 10000～15000r/min, EAT; After dry microcapsules metering, in vacuum, be 0.7～0.9MPa vacuum packaging, get product.
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| CN105433371A (en) * | 2015-10-26 | 2016-03-30 | 浙江海洋学院 | Iron-supplementing medicinal granules based on tuna hemoglobin and preparation method thereof |
| CN105901706A (en) * | 2016-04-21 | 2016-08-31 | 长江大学 | Goose blood anti-oxidizing hydrolysate and preparation method of microcapsule therewith |
| CN108651995A (en) * | 2017-04-01 | 2018-10-16 | 新疆喀什昆仑翠翎鸽业有限责任公司 | One kind is rich in active peptides dove Blood piece agent and preparation method thereof of enriching blood |
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| CN105901706B (en) * | 2016-04-21 | 2019-01-25 | 长江大学 | A kind of preparation method of the anti-oxidant hydrolysate of goose blood and its microcapsules |
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Application publication date: 20130612 |