CN103125933B - Liver and gallbladder calculus removing product - Google Patents
Liver and gallbladder calculus removing product Download PDFInfo
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- CN103125933B CN103125933B CN201310021588.4A CN201310021588A CN103125933B CN 103125933 B CN103125933 B CN 103125933B CN 201310021588 A CN201310021588 A CN 201310021588A CN 103125933 B CN103125933 B CN 103125933B
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Abstract
The invention provides food or a health care product having a liver and gallbladder calculus removing effect. A liver and gallbladder calculus removing product comprises a container A and a container B, wherein the container A contains food or drugs causing hypocatharsis, and the container B contains edible oil. In addition, the invention further provides application of the liver and gallbladder calculus removing product in the preparation of the food or the health care product having the liver and gallbladder calculus removing effect.
Description
Invention field
The invention belongs to food/field of health care products, particularly, the present invention relates to have discharging liver and bile stone (especially early stage calculus) food/health products and the application thereof for the treatment of/preventive effect.
Background of invention
The treatment of liver and bile stone mainly by medicine arrange stone, operation is carried out except methods such as stone or ultrasonic wave rubbles, carries out in process comparatively misery and medical treatment cost higher.
In addition, Chinese patent utilizes for No. 00117755 archen and the turpentine oil with cathartic effect to be mixed and made into calculus removal liquid, Chinese patent utilizes for No. 01144895 neurotransmitter phosphatid ylcholine and soybean oil to be mixed and made into the liquid for the treatment of Biliary Calculi, but the medicines such as the archen of pharmaceutical dosage and phosphatid ylcholine in these patents, have been used, Chinese patent 200510003162 grades have also been used the medicine of drug dose in addition, these all need to examine and approve through medicine, and the adding of medicine, also affected the popularization of this product.
And Chinese patent discloses the medicine that main active is the treatment gall stone of peppermint (element) oil for 01134090,200310113428,200410080513 and No. 200510124227, both do not had to point out the material that has the hypocatharsis of causing, and the cost of peppermint (element) oil is also far above oil with common edible.
More seriously, above these patent related products are medicine, can bring side effect, as abnormal in defecation frequency etc., and mouthfeel is not good, more do not have enlightenment to have under the prerequisite used of row's masonry, the material that causes hypocatharsis separates and takes to avoid adding of too much potent medicine with edible oil.
For this reason, the inventor is through long-term endeavour, furtherd investigate the mechanism of action of Dietotherapy method among the people, utilization is lubricated liver and gall pipeline and expands the mechanism that gall-bladder is discharged calculus after making gall-bladder accelerate to shrink, having developed can standardization, commercial product, its curative effect is reliable, convenient and healthy, more can be shortened to 1-2 days the course for the treatment of, especially food/health products of developing, more can accomplish all to use food source property material, take security guaranteed, and can save loaded down with trivial details medicine administrative examination and approval, also be convenient to promote.
Summary of the invention
It is new for discharging liver and bile stone (especially early stage calculus) resultful food/health products and application thereof that the technical problem to be solved in the present invention is to provide.
Particularly, in first aspect, the invention provides and have food or the health products that liver and gall row masonry is used, it comprises container A and container B, and wherein container A comprises the food that causes hypocatharsis, and container B comprises edible oil.Wherein, liver and bile stone is preferably early stage liver and bile stone.Material in container A and container B is separately to pack, and before not taking container A and container B apart, both cannot mix.Preferred container A only comprises the food that causes hypocatharsis.
In this article, " food " and " health products " can Alternate, refer to food or raw-food material that general public is understood, but wherein got rid of the pharmaceutical preparation that < < NF > > records or the bulk drug with pharmaceutically active, comprised the Chinese medicine of having got rid of integration of drinking and medicinal herbs.The use of food or health products only need to meet general health and quality requirement, and without national drug authorization, the approval that medicine is examined flow process is pressed by mechanism.In addition, " causing the food of hypocatharsis " is exactly to have certain profit to rush down food or the raw-food material that acts on but can use according to food.
Preferably, in the food or health products of first aspect present invention, the food that causes hypocatharsis comprises ferment, and plant enzyme especially, as Fructus Chaenomelis ferment, lemon ferment, pineapple ferment and/or apple ferment.It is pointed out that in this article, the definition that " ferment " strictly understood for field of food technical staff, thus be rich in the glycolysis extract that contributes to digestion to cause the protease of certain hypocatharsis effect, be mainly plant glycolysis extract.Conventionally, ferment provides with (freezing) dry powder form, and this can buy by market, also can oneself prepare.This " enzyme " of understanding from field of biological pharmacy technical staff is different concept.
Also preferred in the food or health products of first aspect present invention, the food that causes hypocatharsis comprises beneficial bacteria of intestinal tract, as lactic acid bacteria and/or Bifidobacterium.Wherein, beneficial bacteria of intestinal tract is alive.Preferably wherein beneficial bacteria of intestinal tract is highly active, as viable bacteria amount be wherein greater than 100,000,000/gram, be preferably greater than 500,000,000/gram, more preferably greater than 1,000,000,000/gram.Conventionally, beneficial bacteria of intestinal tract is usingd freeze-dried powder form provides (wherein generally using milk powder as filler), and this can buy by market, also can oneself preparation.
Most preferably all use food source property material.Therefore preferably in the food or health products of first aspect present invention, the food that causes hypocatharsis comprises ferment (as, the mixture of lemon ferment, pineapple ferment and apple ferment) and Bifidobacterium.Preferably wherein, the weight ratio of ferment and Bifidobacterium was 10～50:0.5～3, is preferably 20～35:0.8～1.5, as 24: 1.More preferably wherein, lemon ferment, pineapple ferment and the weight ratio of apple ferment in ferment are 1～20: 1～20: 10～100, be preferably 1.5～5:1.5～5:12～35, and more preferably 2～4: 2～4: 15～20, as 3:3:18.
In container B, except edible oil, can also comprise flavor enhancement, as fruit juice, sugar and/or essence.Container B can only comprise edible oil, also can only comprise edible oil and flavor enhancement.Edible oil can be animal fat, as being one or more mixture of fish oil, cod-liver oil and lard.But for more convenient gain, preferably in the food or health products of first aspect present invention, edible oil is vegetable edible oil, is preferably selected from one or more mixture of flaxseed seed oil, olive oil, coconut oil, sunflower oil, herb mixtures tea oil, rape oil, sunflower oil, sesame oil, apricot kernel oil, soybean oil, corn oil, pumpkin seed oil and peanut oil.
Preferably in the food or health products of first aspect present invention, also comprise and record the description of taking flow process, the described flow process of taking comprises the food of taking in container A, behind interval, take the edible oil in container B, preferably include the food of taking in container A, behind interval, take food or medicine in container A, then take the edible oil in container B.Wherein, be spaced apart 0.3-5 hour, be preferably 0.5-2 hour.Description is conventionally made of paper, also can directly be printed on container A, container B and/or food or health products vessel surface.
Preferably, in the food or health products of first aspect present invention, the quantity of container A is the twice of container B.For example, comprising two container A and a container B, or comprising four container A and two container B, the latter can make majority complete row's stone process.
In second aspect, the invention provides container A and container B and combine in preparation and there is food that liver and gall rows masonry uses or the application in health products, its container A and container B have the definition described in first aspect present invention.Preferably wherein, having food that liver and gall rows masonry uses or health products is food or the health products described in first aspect present invention.
Beneficial effect of the present invention has been to overcome the defect of prior art; effect is reliable; taking convenience, safety and sanitation, can not form by food source property raw material containing medicine; or greatly reduce the use of medicine; thereby avoid or reduced the administrative examination and approval cost of medicine, also avoid or greatly reduced the shortcomings such as side effect that medicine brings and compliance be not good, be convenient to promote; more, by standardized production, be conducive to scale, controlledization, can supervision produce.
Below will to the present invention, be described in detail by specific embodiment.It needs to be noted, these descriptions are only exemplary descriptions, do not form limitation of the scope of the invention.According to the discussion of this description, many variations of the present invention, change have been all obviously concerning one of ordinary skill in the art.In addition, the present invention has quoted open source literature, and these documents are in order more clearly to describe the present invention, its in full content all include in and carry out reference herein, just look like their in full in this article entire teachings gone over.
The specific embodiment
Following examples, for illustrating, are not construed as limiting the invention, and wherein raw materials usedly all can obtain by buying on market.
The scale preparation of embodiment 1 fruit ferment
Fruit (pawpaw, lemon, pineapple or apple) ferment can be prepared according to conventional method, but take for convenient, by its preparation method according to improving to adapt to large-scale production, detailed process is as follows: get clean, the mature fruit pulp of peeling and stoning or son, be cut into 1cm square, with pure water, soak 2 times, each 1 minute, then drain away the water, evenly add sucrose (sucrose: fruit pulp (weight ratio)=5:100), be placed in sterile closed container (fermentation tank), in 15 ± 2 ℃ of natural glycolysis 14 days, then filter and remove alcoholic moisture, the solid retaining and semi-solid part stirring are pulverized postlyophilization to water content and are no more than 5% (weight ratio), obtain respectively can large-scale production all kinds of fruit ferment, after testing, basically identical with quality index prepared by conventional method, can alternative each otherly use.
Embodiment 2 does not arrange the preparation of stone product containing the liver and gall of drug ingedient
Use for fear of any drug ingedient, the fruit ferment mixture that can adopt conventional method to prepare, preferably adopt lemon ferment 3g, pineapple ferment 3g and the apple ferment 18g preparing according to the method for embodiment 1, with Bifidobacterium freeze-dried powder 1g (wherein, Bifidobacterium can detect number of viable for being greater than 1,000,000,000/gram, can nourish forests and streams bio tech ltd purchased from Shaoguan) mix, and can add 5g fructose further to improve mouthfeel, use aseptic In Aluminium Foil Packing, obtain container A; Olive oil 65ml and lemon juice 25ml is simultaneously canned in aseptic aluminium foil, and sealing, obtains container B.
The curative effect of embodiment 3 liver and gall row stone products
The in the situation that of informed consent, by 18, have the volunteer of early stage calculus symptom to be divided at random 3 groups:
Group 3,6 people, take the product of the embodiment of the present invention 2, taking flow process is to open container A at 6 in evening to take, and opens another container A at 8 in evening and takes, opening container B at 10 in evening takes, then 6 of the next mornings open container A and take, 8 of mornings open another container A and take, morning, 8 semi-open container B were taken, main-process stream is no more than 2 days, while taking the liquid of container B, need to first shake up.
Control group: 2 people, according to its daily life, do not take product of the present invention.
Second day starts to observe the excretion situation of respectively organizing volunteer, wherein organizing 3 observes 4 people and has calculus to discharge, and control group is not observed someone and is had calculus to discharge, wherein surprisingly, significantly reduce olive oil consumption and do not used group 3 effects of any drug ingedient not to be weaker than other groups, be but more convenient for taking of volunteer; From compliance, group 3 volunteer feed back container A to take mouthfeel good, each group does not all change volunteer's daily life rhythm substantially, wherein the more daily increase of 2 people's times of defecation is 1 time, it is more daily rarer that 4 people feed back stool, by daily life, more there is not other observable side effects per capita in other.
Claims (20)
1. container A and container B are combined in preparation and are had the application in the food that liver and gall rows masonry uses, wherein container A comprises fruit ferment and the beneficial bacteria of intestinal tract that causes hypocatharsis, container B only comprises edible oil or container B only comprises edible oil and flavor enhancement, take flow process and comprise fruit ferment and the beneficial bacteria of intestinal tract of taking in container A, behind interval, take the edible oil in container B.
2. application claimed in claim 1, wherein the preparation method of fruit ferment is as follows:
Get the mature fruit pulp of clean, peeling and stoning or son, be cut into 1cm square, with pure water, soak 2 times, each 1 minute, then drain away the water, evenly add sucrose, sucrose: the weight ratio=5:100 of fruit pulp, is placed in sterile closed container, in 15 ± 2 ℃ of natural glycolysis 14 days, then filter the alcoholic moisture of removal, the solid of reservation and semi-solid part stir pulverizing postlyophilization to water content and are no more than 5% weight ratio.
3. application claimed in claim 1, wherein fruit ferment is Fructus Chaenomelis ferment, lemon ferment, pineapple ferment and/or apple ferment.
4. application claimed in claim 1, wherein beneficial bacteria of intestinal tract is lactic acid bacteria and/or Bifidobacterium.
5. application claimed in claim 1, wherein container A comprises lemon ferment, pineapple ferment, apple ferment and Bifidobacterium.
6. application claimed in claim 1, wherein edible oil is vegetable edible oil.
7. application claimed in claim 6, wherein edible oil is one or more mixture of flaxseed seed oil, olive oil, coconut oil, sunflower oil, herb mixtures tea oil, rape oil, sunflower oil, sesame oil, apricot kernel oil, soybean oil, corn oil, pumpkin seed oil and peanut oil.
8. application claimed in claim 1, wherein the quantity of container A is the twice of container B.
9. application claimed in claim 8 is wherein two container A and a container B.
10. application claimed in claim 8 is wherein four container A and two container B.
11. container A and container B are combined in preparation and are had the application in the health products that liver and gall rows masonry uses, wherein container A comprises fruit ferment and the beneficial bacteria of intestinal tract that causes hypocatharsis, container B only comprises edible oil or container B only comprises edible oil and flavor enhancement, take flow process and comprise fruit ferment and the beneficial bacteria of intestinal tract of taking in container A, behind interval, take the edible oil in container B.
Application described in 12. claims 11, wherein the preparation method of fruit ferment is as follows:
Get the mature fruit pulp of clean, peeling and stoning or son, be cut into 1cm square, with pure water, soak 2 times, each 1 minute, then drain away the water, evenly add sucrose, sucrose: the weight ratio=5:100 of fruit pulp, is placed in sterile closed container, in 15 ± 2 ℃ of natural glycolysis 14 days, then filter the alcoholic moisture of removal, the solid of reservation and semi-solid part stir pulverizing postlyophilization to water content and are no more than 5% weight ratio.
Application described in 13. claims 11, wherein fruit ferment is Fructus Chaenomelis ferment, lemon ferment, pineapple ferment and/or apple ferment.
Application described in 14. claims 11, wherein beneficial bacteria of intestinal tract is lactic acid bacteria and/or Bifidobacterium.
Application described in 15. claims 11, wherein container A comprises lemon ferment, pineapple ferment, apple ferment and Bifidobacterium.
Application described in 16. claims 11, wherein edible oil is vegetable edible oil.
Application described in 17. claims 16, wherein edible oil is one or more mixture of flaxseed seed oil, olive oil, coconut oil, sunflower oil, herb mixtures tea oil, rape oil, sunflower oil, sesame oil, apricot kernel oil, soybean oil, corn oil, pumpkin seed oil and peanut oil.
Application described in 18. claims 11, wherein the quantity of container A is the twice of container B.
Application described in 19. claims 18 is wherein two container A and a container B.
Application described in 20. claims 18 is wherein four container A and two container B.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310021588.4A CN103125933B (en) | 2012-07-16 | 2013-01-05 | Liver and gallbladder calculus removing product |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210253794 | 2012-07-16 | ||
| CN201210253794.3 | 2012-07-16 | ||
| CN201310021588.4A CN103125933B (en) | 2012-07-16 | 2013-01-05 | Liver and gallbladder calculus removing product |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103125933A CN103125933A (en) | 2013-06-05 |
| CN103125933B true CN103125933B (en) | 2014-02-12 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201310021588.4A Active CN103125933B (en) | 2012-07-16 | 2013-01-05 | Liver and gallbladder calculus removing product |
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| CN (1) | CN103125933B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110089754A (en) * | 2019-04-02 | 2019-08-06 | 大连双迪科技股份有限公司 | Liver and gallbladder health care product |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1184994C (en) * | 2001-12-29 | 2005-01-19 | 中国人民解放军第二六一医院 | Medicine for treating cholecithes and its preparation method |
| CN1981806A (en) * | 2005-12-13 | 2007-06-20 | 李永岚 | Four-component prescription against urethral calculus |
| CN102120005B (en) * | 2010-10-16 | 2014-11-05 | 秦皇岛皇威制药有限公司 | Traditional Chinese medicine for soothing liver, regulating qi and promoting bile flow and preparation method and quality standard thereof |
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Address after: 200331 room 306, Lane 4703, traffic road, Putuo District, Shanghai 306 Patentee after: Hekang Trade Co., Ltd. Address before: 200042 12F, block B, 1118 Changshou Road, Putuo District, Shanghai. Patentee before: Hekang Trade Co., Ltd. |
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