CN103110861B - Granular preparation for preventing infants from getting inflamed and adjusting intestines and stomach and preparation method thereof - Google Patents

Granular preparation for preventing infants from getting inflamed and adjusting intestines and stomach and preparation method thereof Download PDF

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CN103110861B
CN103110861B CN201310073498.XA CN201310073498A CN103110861B CN 103110861 B CN103110861 B CN 103110861B CN 201310073498 A CN201310073498 A CN 201310073498A CN 103110861 B CN103110861 B CN 103110861B
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parts
stomach
preparation
infant
raw material
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CN103110861A (en
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王晓
贺长生
徐海峰
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BEIJING SAN QI MEDICAL TECHNOLOGY RESEARCH INSTITUTE CO., LTD.
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BEIJING SANQI MEDICAL TECHNOLOGY Co Ltd
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Abstract

The invention relates to a granular preparation for preventing infants from getting inflamed and adjusting intestines and stomach and a preparation method thereof. The granular preparation for preventing infants from getting inflamed and adjusting intestines and stomach comprises the following raw materials in parts by weight: 15-30 parts of rhizoma dioscoreae, 2-12 parts of chrysanthemum, 2-12 parts of honeysuckle, 2-12 parts of platycodon grandiflorum, 5-15 parts of cooked coix seeds, 5-25 parts of raw coix seeds, 5-15 parts of corncobs, 1-8 parts of endothelium corneum gigeriae galli, 3-15 parts of medicated leaven, 1-10 parts of radix ophiopogonis, 2-14 parts of roasted malts, 1-8 parts of dried tangerine or orange peels, 1-8 parts of poria cocos, 1-8 parts of fried hawthorns, 0.5-3 parts of xylooligosaccharide, 0.05-0.3 part of bifidobacterium infantis, and 0.05-0.3 part of Lactobacillus acidophilus. According to the invention, through the organic combination of the raw materials, various ingredients with different effects are fused into a product, and the ingredients are mutually cooperated, synergistically act, systemically and completely complement nutrition and regulate the body, thereby achieving the functional effect of preventing infants from getting inflamed and adjusting intestines and stomach.

Description

A kind of infant of prevention granule regulating stomach and preparation method thereof of getting angry
Technical field
The present invention relates to fight and there is granule regulating stomach effect and preparation method thereof on a kind of infant of prevention.
Background technology
Although China is publicizing and is advocating infant's breast-feeding always, but, due to many reasons, the pure breastfeeding rate of baby that current China is born in latter 6 months only 30%, a lot of childs adopt breast milk+artificial milk powder to feed, or adopt the method for artificial milk powder+diatery supplement nursing.Thus, often can cause infant to occur that collywobbles abdomen account, damp and hot constipation, skin sensitivity, agitation easily cry, sleep unpeaceful etc. and feed caused hot gas problem because of milk powder, meanwhile, also can be with symptoms such as halitosis, agitation, vomitings.
For this problem, most people adopt pure Chinese medicinal preparation allotment milk powder or bath, for infant, drink, and to lower because of milk powder, feed the stomach hot gas producing, and still, only this adjusting can not achieve the goal mostly; This is mainly because breast-feeding ratio is low or edible breast milk, in infant's enteron aisle bifidus bacillus than regular meeting fast reducing, and cause reduction and the imbalance of infant's functions of intestines and stomach.So, for the problems referred to above, be not only and will adopt Chinese medicine to regulate, also should increase prebiotics, improve the ratio of probiotic bacterium in infants, to promote growing up healthy and sound of infant.
Summary of the invention
The invention provides a kind of infant of prevention granule regulating stomach and preparation method thereof of getting angry.
Described a kind of infant of prevention gets angry and regulates the granule of stomach, the raw material that contains following weight proportion:
15~30 parts of Chinese yams, 2~12 parts of chrysanthemums, 2~12 parts of Japanese Honeysuckles, 2~12 parts of balloonflower roots, 5~15 parts of the ripe seeds of Job's tears, 5~25 parts of raw pearl barleys, 5~15 parts of corn cobs, 1~8 part of Membrane of Chicken Gizzard, 3~15 parts of Divine Comedy, 1~10 part of the tuber of dwarf lilyturf, 2~14 parts of roasted malts, 1~8 part of dried orange peel, 1~8 part, Poria cocos, 1~8 part of stir-baked FRUCTUS CRATAEGI, 0.5~3 part of xylo-oligosaccharide, 0.05~0.3 part of bifidobacteria infantis, 0.05~0.3 part of Lactobacterium acidophilum;
Described prevention infant gets angry and regulates the granule of stomach, preferably contains the raw material of following weight proportion:
18~26 parts of Chinese yams, 4~10 parts of chrysanthemums, 4~10 parts of Japanese Honeysuckles, 4~10 parts of balloonflower roots, 7~12 parts of the ripe seeds of Job's tears, 8~20 parts of raw pearl barleys, 8~12 parts of corn cobs, 2~6 parts of Membrane of Chicken Gizzard, 5~12 parts of Divine Comedy, 2~7 parts of the tubers of dwarf lilyturf, 5~12 parts of roasted malts, 3~6 parts of dried orange peels, 3~8 parts, Poria cocos, 3~6 parts of stir-baked FRUCTUS CRATAEGIs, 1~2 part of xylo-oligosaccharide, 0.1~0.25 part of bifidobacteria infantis, 0.1~0.25 part of Lactobacterium acidophilum;
Described prevention infant gets angry and regulates the granule of stomach, further preferably contains the raw material of following weight proportion:
20~24 parts of Chinese yams, 5~7 parts of chrysanthemums, 5~7 parts of Japanese Honeysuckles, 5~7 parts of balloonflower roots, 8~11 parts of the ripe seeds of Job's tears, 10~15 parts of raw pearl barleys, 9~11 parts of corn cobs, 3~5 parts of Membrane of Chicken Gizzard, 7~10 parts of Divine Comedy, 3~6 parts of the tubers of dwarf lilyturf, 8~10 parts of roasted malts, 4~5 parts of dried orange peels, 5~7 parts, Poria cocos, 4~5 parts of stir-baked FRUCTUS CRATAEGIs, 1~2 part of xylo-oligosaccharide, 0.1~0.25 part of bifidobacteria infantis, 0.1~0.25 part of Lactobacterium acidophilum.
Described part is the weight unit such as g, kg, ton.
Described have prevention and fight on infant and regulate the granule day dose of stomach effect to be recommended as, every bag of 2g, every day 2-3 time, 1~2g/ time.
Described prevention infant gets angry and regulates the granule of stomach, and preparation method comprises the following steps:
1) raw material extracts: by chrysanthemum, and Japanese Honeysuckle, the ripe seed of Job's tears, raw pearl barley, corn cob, Membrane of Chicken Gizzard, Divine Comedy, the tuber of dwarf lilyturf, roasted malt, dried orange peel, Poria cocos, stir-baked FRUCTUS CRATAEGI, balloonflower root mixes, then adopt the water of 65 ℃-95 ℃ to carry out 2 extractions, extract 5-10 times that amount of water is raw material weight for the 1st time, 3 hours extraction times; Extract 3-5 times that amount of water is raw material weight for the 2nd time, 2 hours extraction times; No. 2 extracting solutions are merged, adopt 200 orders to filter, then vacuum concentration, making proportion is 1.1-1.35g/cm 3concentrated solution;
2) Rhizoma Dioscoreae powder preparation: Chinese yam is pulverized, add the pure water stirring and dissolving of 3~8 times of weight, be heated to 65~85 ℃, gelatinization (30min), vacuum concentration, spraying is dry, is prepared into Chinese yam dry powder;
3) particle preparation: by the concentrated solution of above-mentioned preparation and Chinese yam dry powder blend, then adopt conventional drying method, the dry particle that is prepared into;
4) particle is pulverized: above-mentioned dried particles is pulverized, be prepared into 30~80 object particle fine powders;
5) mix: xylo-oligosaccharide, bifidobacteria infantis, Lactobacterium acidophilum are mixed with above-mentioned particle fine powder, obtain.
Infants milk powder and diatery supplement feed the reason of getting angry be mainly because, infant's stomach is in the etap, the functions such as digestion are not yet sound, assimilate and Self-regulation ability a little less than, due to the food not science of arranging in pairs or groups, superfluous nutritive substance is difficult to digestion, causes production of heat due to retention of food and " getting angry ".In addition, the traditional Chinese medical science is thought: children's is " pure-yang constituent ", and i.e. " getting angry " phenomenon of overabundance of yang hyperactivity of fire easily appears in physique partial heat.
So, for infant, producing the reason of stomach hot gas, the present invention selects to have the health care food materials of strengthening the spleen to promote digestion, promoting diuresis to eliminate damp pathogen targetedly, adjusts and strengthen children's's spleen and stomach function; Select clearing heat and detoxicating health care food materials effectively to dispel disease and evil in child's body, and can build up health; Meanwhile, be aided with the functions of intestines and stomach that probiotic bacterium is improved children's self.Avoid using merely herbal medicine and Chinese herbal medicine decoction, do not increase the weight of children's's liver and taste burden, also can not damage children's self human body function.
One, strengthening the spleen to promote digestion
1, Membrane of Chicken Gizzard: refer to the gizzard inwall of a chicken, these product are that tradition is used for the diseases such as maldigestion, and effect is splendid, so name with " gold ".Membrane of Chicken Gizzard taste is sweet, cold in nature.Return spleen, stomach, small intestine, urinary bladder channel.There is food digesting stomach fortifying, wide middle invigorating the spleen, the effect of the mill stomach that helps digestion.Control children's's breast food knot stagnant, the large muscle of tripe is blue or green, mass in the abdomen infantile malnutrition due to digestive disturbances or intestinalparasites.
2, Divine Comedy: for after the medicines such as polygonum flaccidum, sweet wormwood, almond add flour or wheat bran mixed, the herbal leaven forming through fermentation.Taste is sweet, pungent, warm in nature.Return spleen, stomach warp.Have invigorating the spleen and regulating the stomach, mediation helps digestion.For eating accumulation card.This product has the merit of food digesting stomach fortifying and middle antidiarrheal.
3, Fructus Hordei Germinatus: for the mature fruit of grass barley is through dry the obtaining of germinateing.Taste is sweet, and property is flat.Return spleen, stomach warp, Liver Channel.Promote qi circulation digestion promoting, spleen benefiting and stimulating the appetite.Fructus Hordei Germinatus: be longer than stomach invigorating.Roasted malt: be partial to promote qi circulation digestion promoting.
4, hawthorn: taste is sweet, slightly warm in nature is sour.Energy appetite-stimulating indigestion-relieving, offsets carnivorous stagnant effect better especially, in a lot of digestant medicines, has all adopted hawthorn; Hawthorn can single or with other foods, compatibility of drugs to improve its dietary function.Hawthorn adds the Charred Triplet that Fructus Hordei Germinatus, Divine Comedy etc. are made, and the abdomen that can be used for maldigestion, retention of food and drink is full, heating installation, do not think the diseases such as food.Hawthorn adds Membrane of Chicken Gizzard, invigorating the spleen and regulating the stomach, and long-pendingization that disappear is stagnant, for children's infantile malnutrition symptom due to stopping in dyspepsia, poor appetite, abdominal distention, maldigestion, stool imbalance.Stir-baked FRUCTUS CRATAEGI, function of promoting blood circulation to disperse blood clots reduces, and the effect of promoting digestion and removing stagnated food is strengthened.
Two, promoting diuresis to eliminate damp pathogen
1, the seed of Job's tears: the seed of Job's tears is long at China's cultivation history is one of all good grain kind of the ancient medicine food of China.All produce most areas, the whole nation, take the provinces such as Fujian, Hebei as main, because the nutritive value of the seed of Job's tears is very high, is described as " king of world grass " and " standing grain of life and health ".Seed of Job's tears slightly sweet flavor, cool in nature.Return spleen, stomach, lung channel.There is invigorating the spleen excreting dampness, clearing away heat and eliminating pus, except the function of numbness, Li Shui.Raw pearl barley is partially cold and cool, is longer than promoting diuresis to eliminate damp pathogen; The ripe seed of Job's tears goes its micro-cool property, and property is partially gentle, is longer than invigorating the spleen to arrest diarrhea, so raw ripe seed of Job's tears use is simultaneously got its function and is not afraid of too cold and cool.
2, corn cob: the excellent core after corn rod threshing.Corn cob has identical effect with Stigma Maydis, and meanwhile, because of its sugar that contains 50% left and right, while extracting juice use, local flavor is better.Property slightly sweet flavor and putting down, enters liver, kidney, urinary bladder channel, has the function of inducing diuresis to remove edema, flat liver cholagogic.
3, Poria cocos: for colonizing in the fungi plant on pine root, ancients claim that Poria cocos is " god medicine " at 4 o'clock, because its effect is very extensive, regardless of the four seasons, by it and various compatibility of drugs, no matter cold, temperature, wind, all diseases that wets can be brought into play its unique effects.Poria cocos taste is sweet, light, property flat, thoughts of returning home warp, lung channel, the spleen channel, kidney channel.Be used as medicine there is promoting diuresis to eliminate damp pathogen, the function of beneficial spleen and stomach, tranquillizing by calming the heart.
Poria cocos and Chinese yam, the Fructus Hordei Germinatus collocation infantile dyspepsia that can disappear, anorexia; Have loose bowels with the seed of Job's tears, the dried orange peel collocation infantile spleen deficiency that can disappear, dysuria; Poria cocos and the collocation tuber of dwarf lilyturf can be used for eliminating insufficiency of heart-YIN, ambition dysphoria with smothery sensation, palpitation with fear insomnia, dry mouth and tougue.
Three, clearing heat and detoxicating
1, chrysanthemum: be the conventional clearing heat and detoxicating drink of China, there is the effect of dispelling wind, heat-clearing, improving eyesight, removing toxic substances.
2, Japanese Honeysuckle: be from ancient times described as clearing heat and detoxicating good medicine.The sweet cold air of its property fragrance, clearing away heat with drugs sweet in flavor and cold in nature and not injuring one's stomach, fragrance thoroughly reaches and can be eliminating evil.There are clearing heat and detoxicating, dispelling wind and heat pathogens, dredge the effect of throat, the relieving restlessness of relieving summer heat.
Four, help is promoted the production of body fluid
1, the tuber of dwarf lilyturf: sweet, micro-hardship, is slightly cold.The thoughts of returning home, lung, stomach warp.Have nourishing Yin and promoting production of body fluid, moistening lung clears away heart-fire, the effect that relieving restlessness is quenched the thirst.For dryness of the lung dry cough, Tianjin wound is thirsty, vexed insomnia, and interior heat is quenched one's thirst, the dry constipation of intestines.
2, balloonflower root: bitter, pungent, property is flat.Return lung channel.There is a surname's lung, eliminate the phlegm, relieve sore throat, apocenosis, sharp the five internal organs, the effect that fills blood, mend the exhaustion or lesion of the five internal organs, foster the spirit of nobility.
3, dried orange peel: warm in nature, taste is pungent, bitter.Enter the spleen channel, stomach warp, lung channel.Have regulating qi-flowing for strengthening spleen, in tune, eliminating dampness, reduces phlegm.Cure mainly the distension and fullness in the abdomen of the taste stagnation of the circulation of vital energy or pain, maldigestion.Dried orange peel has three major types effect, and the one, lead cold-evil in the heart, two broken stagnant gas, three beneficial taste.This three greatly on, Main Function is row QI of the spleen and stomach.
4, Chinese yam: Chinese yam contains the materials such as amylase, polyphenoloxidase, is conducive to taste digestion and absorption function is the good merchantable brand of the medicine-food two-purpose of flat tonifying the spleen and stomach simply.Chinese yam, taste is sweet, and property is flat.Return spleen, lung, kidney channel.Tonifying spleen nourishing the stomach, the beneficial lung that promotes the production of body fluid, the puckery essence of kidney tonifying.Few for insufficiency of the spleen food, chronic diarrhea, the deficiency syndrome of the lung is breathed with cough, emission due to deficiency of the kidney, under band, frequent micturition, abnormal heat is quenched one's thirst.
Five, prebiotics
1, xylo-oligosaccharide: claiming again wood oligose, is the functional polymerization sugar being combined into β-Isosorbide-5-Nitrae glycosidic link by 2-7 wood sugar molecule.The soybean oligosaccharide used with common people, oligofructose, oligomeric isomaltose etc. are compared has unique advantage, and it can optionally promote the proliferation activity of intestinal bifidobacteria.Xylo-oligosaccharide is in polymerization carbohydrate, to breed one of kind that bifidus bacillus function is the strongest, its effect is nearly 20 times of other polymerization carbohydrates, in human gastrointestinal tract, be not hydrolyzed the enzyme of xylo-oligosaccharide, so it can directly enter and be preferably bifidus bacillus in large intestine and utilize, promote bifidus bacillus propagation to produce multiple organic acid simultaneously.Reduce enteron aisle pH value, suppress harmful bacteria growth, probiotic bacterium is bred in a large number at enteron aisle.
2, bifidobacteria infantis: in human intestinal, bacterial flora is along with people's age increase is changed significantly.Within after baby due 3~4 days, in enteron aisle, occur bifidus bacillus, infant's bifidobacteria accounts for 25% of about intestinal bacterium total amount; Along with the increase at age, bifidus bacillus reduces even disappearance gradually, the old man of over-65s, and bifidobacteria reduces to and only accounts for 7.9%, and the putrefactive bacteriums such as aerogenesis pod clostridium, intestinal bacteria roll up; Because bifidus bacillus goods are able to widespread use at world wide, broad masses have recognized that its importance.Particularly can for infant's intestinal health, provide unique provide protection, effectively reduce the sickness rate of infant's intestinal tract infections.
Improve bifidus bacillus quantity in vivo and have two kinds of methods: " viable bacteria is external takes a tonic or nourishing food to build up one's health " and " viable bacteria proliferation in vivo "." viable bacteria is external takes a tonic or nourishing food to build up one's health " is exactly the oral active bacteria formulation that has some amount bifidus bacillus.
3, Lactobacterium acidophilum: there is the intestinal microflora of adjustment balance, suppress the effect of the propagation of enteron aisle undesirable microorganism.One mentions bifidus bacillus, and much people know, it is the main probiotic bacterium in large intestine; And Lactobacterium acidophilum is not only under one's belt, the main probiotic bacterium in it or human small intestine.This two quantity is huge, mutually helps, and by safeguarding whole GI microecological balance, plays the effect promoting health.
Lactobacterium acidophilum in the whole gi tract of human body, " from top to down " microecosystem regulation environment.D score refers in large intestine, they also can releasing beneficial bifidus bacillus etc. the material of other probiotic bacteriums growths, increase probiotic bacterium in large intestine quantity, strengthen their vitality.
Preparation method's advantage of the present invention is:
1) with roasted malt, stir-baked FRUCTUS CRATAEGI, Membrane of Chicken Gizzard, Divine Comedy is monarch, invigorating the spleen and regulating the stomach, helps digestion and amasss; With chrysanthemum, Japanese Honeysuckle is minister, clearing heat and detoxicating, dispelling wind and heat pathogens; Take the tuber of dwarf lilyturf, balloonflower root, dried orange peel, Chinese yam as assistant, help is promoted the production of body fluid, regulating qi-flowing for strengthening spleen; With the seed of Job's tears, corn cob, Poria cocos for making, inducing diuresis to remove edema, tranquillizing by calming the heart.Monarch is mutually auxiliary to multiply each other, and reaches strengthening the spleen to promote digestion, promoting diuresis to eliminate damp pathogen, alleviate and eliminate infant due to assimilate and Self-regulation ability compared with weak collywobbles abdomen account, damp and hot constipation, skin sensitivity, the agitation the causing symptom such as unpeaceful of easily crying, sleep.
2) add especially prebiotics, be conducive to improve infant's enteron aisle function, improve Self-regulation ability, promote pharmaceutically-active performance.
3) Chinese yam is one of invention product effective constituent, and it has tonifying spleen nourishing the stomach, and the effect of the beneficial lung that promotes the production of body fluid has good curative effect to baby's maldigestion, pre-anti-diarrhea simultaneously.Utilize Chinese yam as the carrier of other material compositions, and avoid using other food auxiliary materials, cause infant's gastrointestinal upset, or infant's physique is caused to other adverse influences.
4) effective constituent in raw material, through extracting and decocting, then loads to effective constituent on the Rhizoma Dioscoreae powder after overcuring, is conducive to instant edible.
5) dried particles is pulverized again, mixed with prebiotics, because prebiotics consumption is less, can guarantee to be uniformly dispersed, meanwhile, fine powder is dissolved is more conducive to quick dissolving, and concentrated liquid also more can discharge fast and spread in water.
6) preparation method provided by the present invention, due to Chinese yam has been carried out to gelatinization processing, so, make product of the present invention not only there is quick dissolving, meanwhile, can also directly adopt warm water to take after mixing it with water, edible more convenient.
The present invention, by above raw material is organically combined, incorporates multiple different efficacies composition in product, and these compositions cooperatively interact, synergy, and system supplements the nutrients all sidedly, conditioning engine body, reaches on prevention infant and fights and regulate the functional effect of stomach.Product of the present invention can regulate infant's body, lowers because of milk powder and feeds the stomach hot gas producing, and also by increasing prebiotics, improves the ratio of probiotic bacterium in infants, improves infant's functions of intestines and stomach, to promote growing up healthy and sound of infant.
Embodiment
Embodiment 1
Prevention infant gets angry and regulates granule and the preparation method of stomach:
1, take the raw material of following weight proportion:
7 parts of chrysanthemums, 6 parts of Japanese Honeysuckles, 7 parts of balloonflower roots, 10 parts of the ripe seeds of Job's tears, 10 parts of raw pearl barleys, 10 parts of corn cobs, 3 parts of Membrane of Chicken Gizzard, 10 parts of Divine Comedy, 5 parts of the tubers of dwarf lilyturf, 8 parts of roasted malts, 5 parts of dried orange peels, 5 parts, Poria cocos, 5 parts of stir-baked FRUCTUS CRATAEGIs.
2, above-mentioned raw materials is adopted the water of 65 ℃-95 ℃ carry out 2 times and extract, extract 8 times that amount of water is raw material weight, 3 hours extraction times the 1st time; Extract 4 times that amount of water is raw material weight, 2 hours extraction times the 2nd time; No. 2 extracting solutions are merged, adopt 200 orders to filter, then vacuum concentration, making proportion is 1.2g/cm 3concentrated solution.
3, by 20 parts of pulverizing of Chinese yam, add the pure water of 5 times of weight to dissolve, be under agitation heated to 75 ℃ ± 5 ℃, keep 30min, make Chinese yam dry powder after then concentrated, spray-dried.
4, take the Chinese yam dry powder that step 3 is made, under agitation condition, add the prepared concentrated solution of step 2, make according to a conventional method dried particles.
5, dried particles is pulverized, crossed 60 mesh sieves, then with 1.5 parts of xylo-oligosaccharides, 0.2 part of bifidobacteria infantis, 0.2 part of mixing of Lactobacterium acidophilum, after mixing, according to the packaged of 2g/ bag, is prevention infant and gets angry and regulate the granule finished product of stomach.
Embodiment 2
Prevention infant gets angry and regulates granule and the preparation method of stomach:
1, take the raw material of following weight proportion:
4 parts of chrysanthemums, 4 parts of Japanese Honeysuckles, 4 parts of balloonflower roots, 7 parts of the ripe seeds of Job's tears, 8 parts of raw pearl barleys, 8 parts of corn cobs, 2 parts of Membrane of Chicken Gizzard, 5 parts of Divine Comedy, 2 parts of the tubers of dwarf lilyturf, 5 parts of roasted malts, 3 parts of dried orange peels, 3 parts, Poria cocos, 3 parts of stir-baked FRUCTUS CRATAEGIs.
2, above-mentioned raw materials is adopted the water of 65 ℃-95 ℃ carry out 2 times and extract, extract 5 times that amount of water is raw material weight, 3 hours extraction times the 1st time; Extract 3 times that amount of water is raw material weight, 2 hours extraction times the 2nd time; No. 2 extracting solutions are merged, adopt 200 orders to filter, then vacuum concentration, making proportion is 1.3g/cm 3concentrated solution.
3, by 18 parts of pulverizing of Chinese yam, with the pure water of 4 times of weight, dissolve, be under agitation heated to 75 ℃ ± 5 ℃, keep 30 minutes, then, make Chinese yam dry powder after concentrated, spray-dried.
4, take the Chinese yam dry powder that step 3 is made, under agitation condition, add the prepared concentrated solution of step 2, make according to a conventional method dried particles.
5, dried particles is pulverized, crossed 60 mesh sieves, then with 1 part of xylo-oligosaccharide, 0.1 part of bifidobacteria infantis, 0.1 part of mixing of Lactobacterium acidophilum, after mixing, according to the packaged of 2g/ bag, is prevention infant and gets angry and regulate the granule finished product of stomach.
Embodiment 3
Prevention infant gets angry and regulates granule and the preparation method of stomach:
1, take the raw material of following weight proportion:
10 parts of chrysanthemums, 10 parts of Japanese Honeysuckles, 10 parts of balloonflower roots, 12 parts of the ripe seeds of Job's tears, 20 parts of raw pearl barleys, 12 parts of corn cobs, 6 parts of Membrane of Chicken Gizzard, 12 parts of Divine Comedy, 7 parts of the tubers of dwarf lilyturf, 12 parts of roasted malts, 6 parts of dried orange peels, 8 parts, Poria cocos, 6 parts of stir-baked FRUCTUS CRATAEGIs.
2, above-mentioned raw materials is adopted the water of 65 ℃-95 ℃ carry out 2 times and extract, extract 10 times that amount of water is raw material weight, 3 hours extraction times the 1st time; Extract 5 times that amount of water is raw material weight, 2 hours extraction times the 2nd time; No. 2 extracting solutions are merged, adopt 200 orders to filter, then vacuum concentration, making proportion is 1.15g/cm 3concentrated solution.
3, by 26 parts of pulverizing of Chinese yam, with the pure water of 7 times of weight, dissolve, be under agitation heated to 75 ℃ ± 5 ℃, keep 30min, make Chinese yam dry powder after then concentrated, spray-dried.
4, take the Chinese yam dry powder that step 3 is made, under agitation condition, add the prepared concentrated solution of step 2, make according to a conventional method dried particles.
5, dried particles is pulverized, crossed 60 mesh sieves, then with 2 parts of xylo-oligosaccharides, 0.25 part of bifidobacteria infantis, 0.25 part of mixing of Lactobacterium acidophilum, after mixing, according to the packaged of 2g/ bag, is prevention infant and gets angry and regulate the granule finished product of stomach.
Embodiment 4
The raw material that prevention infant gets angry and regulates the granule of stomach to contain following weight proportion:
20 parts of Chinese yams, 7 parts of chrysanthemums, 6 parts of Japanese Honeysuckles, 7 parts of balloonflower roots, 10 parts of the ripe seeds of Job's tears, 10 parts of raw pearl barleys, 10 parts of corn cobs, 3 parts of Membrane of Chicken Gizzard, 10 parts of Divine Comedy, 5 parts of the tubers of dwarf lilyturf, 8 parts of roasted malts, 5 parts of dried orange peels, 5 parts, Poria cocos, 5 parts of stir-baked FRUCTUS CRATAEGIs, 1.5 parts of xylo-oligosaccharides, 0.2 part of bifidobacteria infantis, 0.2 part of Lactobacterium acidophilum.
Preparation method is with embodiment 1.
Product crowd test-meal effect observation test of the present invention
(test sample is the granule of embodiment 1 preparation)
1, crowd's screening: choose 50 effect tests that participate in product of the present invention of infant of 3-12 month, wherein, 32 of male sex infants, 18 of women infants.Participate in the experiment and have the auxiliary milk powder of 30 breast milks by name to feed in infant, with the auxiliary meal food of milk powder, feed for 20.
2, eating method:
1) 6 months Infants Belows, each half bag (approximately 1 gram), every day 2-3 time, after dissolving by warm water, place of water is drunk, or for dissolved milk powder, feeding.
2) 6 months above infants, each 1 bag (2 grams), every day 2-3 time, after dissolving by warm water, place of water is drunk, or for dissolved milk powder and other complementary food, feeding.
3, result is observed:
1) damp and hot constipation: June Infants Below 5 people, be the auxiliary milk powder of breast milk and feed, take continuously after 5 days effective 3 people, efficient 60%; June above infant 15 people, wherein, the auxiliary milk powder of breast milk is fed 9 people, the auxiliary meal food of milk powder is fed 6 people, take continuously 5 days, it is 7 people (efficient is 77.8%) that the auxiliary milk powder of breast milk is fed efficiently individual quantity, and it is 5 people (efficient is 83.3%) that the auxiliary meal food of milk powder is fed efficiently individual quantity, amounting to efficiently individual quantity is 12 people, and average effectiveness level is 80%.
2) agitation is easily cried, sleeps unpeaceful: June Infants Below 10 people, wherein 7 people are the auxiliary milk powder nursing of breast milk, 3 people are the auxiliary meal food nursing of milk powder, take continuously after 5 days, it is 2 people (efficient is 28.6%) that the auxiliary milk powder of breast milk is fed efficiently individual quantity, the auxiliary meal food of milk powder is fed 3 people all effective (efficient is 100%), and amounting to efficiently individual quantity is 5 people, and average effectiveness level is 50%;
June above infant 20 people, wherein 12 people are the auxiliary milk powder nursing of breast milk, 8 people are the auxiliary meal food nursing of milk powder, take continuously 5 days, it is 8 people (efficient is 66.7%) that the auxiliary milk powder of breast milk is fed efficiently individual quantity, it is 7 people (efficient is 87.5%) that the auxiliary meal food of milk powder is fed efficiently individual quantity, amounts to effective 15 people, and average effectiveness level is 75%.
Above-mentioned test-results explanation, the present invention is for adopting the auxiliary milk powder of breast milk to feed, or the infant who adopts the auxiliary meal food of milk powder to feed the collywobbles abdomen account, damp and hot constipation, the agitation that the occur problem such as unpeaceful of easily crying, sleep all has significant alleviation and health care prophylactic effect.

Claims (4)

1. prevent infant to get angry and regulate a granule for stomach, by the raw material of following weight proportion, made:
15~30 parts of Chinese yams, 2~12 parts of chrysanthemums, 2~12 parts of Japanese Honeysuckles, 2~12 parts of balloonflower roots, 5~15 parts of the ripe seeds of Job's tears, 5~25 parts of raw pearl barleys, 5~15 parts of corn cobs, 1~8 part of Membrane of Chicken Gizzard, 3~15 parts of Divine Comedy, 1~10 part of the tuber of dwarf lilyturf, 2~14 parts of roasted malts, 1~8 part of dried orange peel, 1~8 part, Poria cocos, 1~8 part of stir-baked FRUCTUS CRATAEGI, 0.5~3 part of xylo-oligosaccharide, 0.05~0.3 part of bifidobacteria infantis, 0.05~0.3 part of Lactobacterium acidophilum.
2. prevent according to claim 1 infant to get angry and regulate the granule of stomach, by the raw material of following weight proportion, made:
18~26 parts of Chinese yams, 4~10 parts of chrysanthemums, 4~10 parts of Japanese Honeysuckles, 4~10 parts of balloonflower roots, 7~12 parts of the ripe seeds of Job's tears, 8~20 parts of raw pearl barleys, 8~12 parts of corn cobs, 2~6 parts of Membrane of Chicken Gizzard, 5~12 parts of Divine Comedy, 2~7 parts of the tubers of dwarf lilyturf, 5~12 parts of roasted malts, 3~6 parts of dried orange peels, 3~8 parts, Poria cocos, 3~6 parts of stir-baked FRUCTUS CRATAEGIs, 1~2 part of xylo-oligosaccharide, 0.1~0.25 part of bifidobacteria infantis, 0.1~0.25 part of Lactobacterium acidophilum.
3. prevent according to claim 1 infant to get angry and regulate the granule of stomach, by the raw material of following weight proportion, made:
20~24 parts of Chinese yams, 5~7 parts of chrysanthemums, 5~7 parts of Japanese Honeysuckles, 5~7 parts of balloonflower roots, 8~11 parts of the ripe seeds of Job's tears, 10~15 parts of raw pearl barleys, 9~11 parts of corn cobs, 3~5 parts of Membrane of Chicken Gizzard, 7~10 parts of Divine Comedy, 3~6 parts of the tubers of dwarf lilyturf, 8~10 parts of roasted malts, 4~5 parts of dried orange peels, 5~7 parts, Poria cocos, 4~5 parts of stir-baked FRUCTUS CRATAEGIs, 1~2 part of xylo-oligosaccharide, 0.1~0.25 part of bifidobacteria infantis, 0.1~0.25 part of Lactobacterium acidophilum.
4. according to the arbitrary described prevention infant of claim 1-3, get angry and regulate the granule of stomach, preparation method comprises the following steps:
1) raw material extracts: by chrysanthemum, and Japanese Honeysuckle, the ripe seed of Job's tears, raw pearl barley, corn cob, Membrane of Chicken Gizzard, Divine Comedy, the tuber of dwarf lilyturf, roasted malt, dried orange peel, Poria cocos, stir-baked FRUCTUS CRATAEGI, balloonflower root mixes, then adopt the water of 65 ℃-95 ℃ to carry out 2 extractions, extract 5-10 times that amount of water is raw material weight for the 1st time, 3 hours extraction times; Extract 3-5 times that amount of water is raw material weight for the 2nd time, 2 hours extraction times; No. 2 extracting solutions are merged, adopt 200 orders to filter, then vacuum concentration, making density is 1.1-1.35g/cm 3concentrated solution;
2) Rhizoma Dioscoreae powder preparation: Chinese yam is pulverized, add the pure water stirring and dissolving of 3~8 times of weight, be heated to 65~85 ℃, gelatinization 30min, vacuum concentration, spraying is dry, is prepared into Chinese yam dry powder;
3) particle preparation: by the concentrated solution of above-mentioned preparation and Chinese yam dry powder blend, then adopt conventional drying method, the dry particle that is prepared into;
4) particle is pulverized: above-mentioned dried particles is pulverized, be prepared into 30~80 object particle fine powders;
5) mix: xylo-oligosaccharide, bifidobacteria infantis, Lactobacterium acidophilum are mixed with above-mentioned particle fine powder, obtain.
CN201310073498.XA 2013-03-07 2013-03-07 Granular preparation for preventing infants from getting inflamed and adjusting intestines and stomach and preparation method thereof Expired - Fee Related CN103110861B (en)

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