CN103083676A - Hollow hard capsules - Google Patents
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- CN103083676A CN103083676A CN 201110340463 CN201110340463A CN103083676A CN 103083676 A CN103083676 A CN 103083676A CN 201110340463 CN201110340463 CN 201110340463 CN 201110340463 A CN201110340463 A CN 201110340463A CN 103083676 A CN103083676 A CN 103083676A
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Abstract
The invention belongs to the technical field of enteric-coated capsules, and especially relates to hollow hard capsules with a sweet taste. The capsules are prepared from gelatin, starch, cellulose, and glycerol. The capsules also comprise, by weight, 10-30 parts of auxiliary materials and 1-5 parts of a sweetening agent. According to the invention, traditional Chinese medicines mint with a sweet and cooling taste and licorice root, and a proper amount of a sweetening agent are adopted, such that the produced hard hollow capsules are provided with a good taste. The capsules can be used for coating children-use medicines with bitter or irritating tastes. With the capsules, children medication pains can be greatly relieved. The capsules are also suitable for various populations. According to the invention, preparation raw materials and medicine materials have no toxic or side effects. The process is simple and reasonable, the cost is low, and the capsules are safe and reliable. According to the invention, no added device is needed, and production can be carried out by pharmaceutical factories or capsule production factories. The capsules are suitable for large-scale productions of pharmacy-related enterprises, and have good market prospect.
Description
Technical field
The invention belongs to the technical field of enteric coated capsule, relate in particular to a kind of empty hard capsule with fragrant and sweet mouthfeel.
Background technology
At present; the capsule that generally uses both at home and abroad is all a kind of shells of protecting medicine; be used for the powder charge thing; and capsule commonly used is all to place some to esophagus and gastric mucosa powder excitatory or granular medicine; or mouthfeel bad, be easy to volatilization, easily decomposed and the medicine that easily sucks trachea by saliva in the oral cavity.These medicines incapsulate, and have both protected the medicine property of medicine not to be destroyed, and have also protected digestive organs and respiratory tract.In addition, some medicine need to be at the enteral solution absorption, and capsule is also as a kind of medicament protection shell, and the protection medicine is not by stomach acids destroy.
The raw material of Capsules is gelatin, and pharmagel is raw material with Os Bovis seu Bubali or Os Sus domestica.Capsule is used extraordinary filmogen pharmaceutically typically referring to, the bladder of making as gelatin, cellulose etc., then content; As powdery, liquid various kinds of drug etc. or according to dosage pack into wherein, be convenient to swallow.Usually arranged dividing of hard capsule and soft capsule.Hard capsule claims again Capsules, is comprised of cap body two parts; Soft capsule is that filmogen and content are processed into product simultaneously.Hard capsule divides according to raw material, and it is in the world most popular two-segment type capsule that capsule generally comprises gelatine capsule.These capsules one commonly used are all to add adjuvant with gelatin to be prepared into, and are tasteless, and the mouthfeel that has nothing special is unsuitable for children taking.
In daily life, some irritant tastes of children taking or more pained medicine are to thing that is difficult to accomplish of head of a family Lai Shuoshi, especially some young infant.Mouthfeel bad medicine child can not like taking, and concerning some ill children, original sick is exactly the thing of a misery, takes again the bitter medicine that tastes bad, and does not like concerning the adult, in addition be child.For this worldwide ubiquitous problem, how to produce a kind of existing bitter medicine that can be used for replacing, or tasteless capsule without any mouthfeel encases bitter medicine, children are taken under joyful mood, slight illness is obtained medical treatment early, is also the present large technical problem of constantly researching and solving of workers of pharmaceuticals industry.
Summary of the invention
The present invention is directed to problems of the prior art, purpose is to provide a kind of empty hard capsule, and it has fragrant and sweet mouthfeel, the distinguishing feature that is easy to take.
The objective of the invention is to be achieved through the following technical solutions:
Empty hard capsule is formulated by gelatin, starch, cellulose, glycerol, and it also comprises: the adjuvant of 10-30 part and 1-5 part sweeting agent by ratio of weight and the number of copies.
Described adjuvant comprises: Herba Menthae, Radix Glycyrrhizae.
Described sweeting agent comprises: glucose, fructose, sucrose, maltose, starch sugar and lactose.
Herba Menthae is one of Chinese conventional Chinese medicine.It can be used for hot cool property sweating antipyretic medicine, controls influenza, headache, conjunctival congestion, fever of the body, throat, the dental bed disease such as swell and ache.But external training the mind dysmenorrhoea, skin pruritus, erythra and eczema etc.Herba Menthae again can be as the fresh vegetable on people's dining table, and is clearly good to eat.Usually all right Herba Menthae is for tea, and clearing away heart-fire makes eye bright.Herba Menthae has extremely strong sterilization antibacterial action, often drinks its energy preventing viral flu, oral disease, makes breath freshening.
Radix Glycyrrhizae is a kind of tonification Chinese herbal medicine.Medicinal part is root and rhizome, and the Medicinal Materials Characters root is cylindrical, and the crust degree of tightness differs, the brown or taupe brown of surface red.Rhizome is cylindrical, and there is the bud trace on the surface, and marrow is arranged in the middle part of section.The feeble QI flavor is sweet and special, and function cures mainly heat-clearing and toxic substances removing, expelling phlegm for arresting cough, gastral cavity abdomen etc.Radix Glycyrrhizae is the clinical medicine of the most often using, Radix Glycyrrhizae energy heat-clearing and toxic substances removing, nourishing the lung to arrest cough, coordinating the actions of various ingredients in a prescription; Radix Glycyrrhizae Preparata energy invigorating the spleen and replenishing QI, quantity is especially big, and export volume is large.Except medicinal, also cook the cake additive with Radix Glycyrrhizae in a large number on food, its sugariness is the Radix Achyranthis Bidentatae of sucrose.
The present invention is owing to adopting the Herba Menthae with fragrant and sweet refrigerant taste in Chinese medicine and Radix Glycyrrhizae and appropriate sweeting agent as adjuvant, make the hard Capsules of producing have mouthfeel preferably, be fit to pack as the medicine of some mouthfeels hardships or irritant taste to the child and take.Can alleviate widely the misery that the sufferer Children's Solving is taken medicine, make ill children take medicine under a kind of joyful mood, to help their early recovery, also reduce numerous father and mother and mediated the difficulty that child takes medicine.Simultaneously product of the present invention also is suitable for all kinds of crowds and uses, and the present invention also has conveniently and takes, and effectively covers medicine taste and abnormal smells from the patient, and the transparent visible advantage of content more has the unexistent fragrant and sweet taste of traditional gelatine capsule simultaneously.
The present invention compares with tasteless capsule in the past, and easily by people, especially the child accepts.Also have good bioavailability, can be rapid, reliable and dissolved safely.Raw materials of the present invention and medical material all have no side effect, technique advantages of simple, cost are low, safe and reliable, pharmaceutical factory or capsule manufacture enterprise need not increase original production equipment and can produce, and are applicable to the pharmacy relevant enterprise and produce in enormous quantities, have market prospect preferably.
Below in conjunction with specific embodiment to the present invention's detailed being described below in addition.
The specific embodiment
Embodiment 1:
The present invention is a kind of empty hard capsule, is formulated by gelatin, starch, cellulose, glycerol: also comprise adjuvant and 1 part of sweeting agent of 10 parts by ratio of weight and the number of copies.Described adjuvant is Herba Menthae, and the sweeting agent of stating is glucose.Its production technology gets final product according to existing traditional processing technology.
Embodiment 2:
The present invention is a kind of empty hard capsule, is formulated by gelatin, starch, cellulose, glycerol: also comprise adjuvant and 3 parts of sweeting agents of 20 parts by ratio of weight and the number of copies.Described adjuvant is Radix Glycyrrhizae, and described sweeting agent is fructose.Its production technology gets final product according to existing traditional processing technology.
Embodiment 3:
The present invention is a kind of empty hard capsule, is formulated by gelatin, starch, cellulose, glycerol: also comprise adjuvant and 5 parts of sweeting agents of 30 parts by ratio of weight and the number of copies.Described adjuvant is Herba Menthae, and the sweeting agent of stating is sucrose.Its production technology gets final product according to existing traditional processing technology.
Embodiment 4:
The present invention is a kind of empty hard capsule, is formulated by gelatin, starch, cellulose, glycerol: also comprise adjuvant and 2 parts of sweeting agents of 15 parts by ratio of weight and the number of copies.Described adjuvant is Herba Menthae, and the sweeting agent of stating is maltose.Its production technology gets final product according to existing traditional processing technology.
Embodiment 5:
The present invention is a kind of empty hard capsule, is formulated by gelatin, starch, cellulose, glycerol: also comprise adjuvant and 5 parts of sweeting agents of 25 parts by ratio of weight and the number of copies.Described adjuvant is Herba Menthae, and the sweeting agent of stating is starch sugar.Its production technology gets final product according to existing traditional processing technology.
Embodiment 6:
The present invention is a kind of empty hard capsule, is formulated by gelatin, starch, cellulose, glycerol: also comprise adjuvant and 4 parts of sweeting agents of 15 parts by ratio of weight and the number of copies.Described adjuvant is Radix Glycyrrhizae, and described sweeting agent is lactose.Its production technology gets final product according to existing traditional processing technology.
Claims (3)
1. empty hard capsule is formulated by gelatin, starch, cellulose, glycerol, it is characterized in that: also comprise: the adjuvant of 10-30 part and 1-5 part sweeting agent by ratio of weight and the number of copies.
2. empty hard capsule according to claim 1, it is characterized in that: described adjuvant comprises: Herba Menthae, Radix Glycyrrhizae.
3. empty hard capsule according to claim 1, it is characterized in that: described sweeting agent comprises: glucose, fructose, sucrose, maltose, starch sugar and lactose.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110340463 CN103083676A (en) | 2011-11-02 | 2011-11-02 | Hollow hard capsules |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110340463 CN103083676A (en) | 2011-11-02 | 2011-11-02 | Hollow hard capsules |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103083676A true CN103083676A (en) | 2013-05-08 |
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ID=48197147
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201110340463 Pending CN103083676A (en) | 2011-11-02 | 2011-11-02 | Hollow hard capsules |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103083676A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105769811A (en) * | 2016-05-05 | 2016-07-20 | 夏放军 | Empty starch capsule and preparation method thereof |
| CN105816439A (en) * | 2016-05-12 | 2016-08-03 | 夏放军 | Gelatin empty capsule and preparation method thereof |
| CN105853390A (en) * | 2016-05-20 | 2016-08-17 | 夏放军 | Natural harmless hollow capsules and preparation method thereof |
-
2011
- 2011-11-02 CN CN 201110340463 patent/CN103083676A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105769811A (en) * | 2016-05-05 | 2016-07-20 | 夏放军 | Empty starch capsule and preparation method thereof |
| CN105816439A (en) * | 2016-05-12 | 2016-08-03 | 夏放军 | Gelatin empty capsule and preparation method thereof |
| CN105853390A (en) * | 2016-05-20 | 2016-08-17 | 夏放军 | Natural harmless hollow capsules and preparation method thereof |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20130508 |